GH def./Meridian Valley Test ?-ANDY & OTHERS

May 12, 2010

My 15 yo son was recently diagnosed with growth hormone deficiency (he is 6'2 " ).

His mainstream Endo did 2 growth hormone stimulation test using clonidine for

one test and carbidopa on 2nd test. Test results were: .06 & .05 with ref.

range of .10-8.80

The Endo did the testing b/c of my concerns with hg poisoning/injury to

pituitary and the fact my son had many of the gh def. symptoms: weight gain,

very low energy, high triglycerides, etc.

During the process of getting insurance to approve the 8k per month gh treatment

I sought out the help of another medical provider b/c the mainsream Endo was not

getting the approval/faxing over info to insurance company. The 2nd medical

provider is a alternative NP who specializes in hormones and did a Meridian

Valley Comprehensive PLUS Hormone Profile with HGH.

The Meridian Valley test is a urine test. My son's hgh level on this test was

in ref range. Amount excreted in 24 hr. urine was 3328 with ref. range of

1065-4722 (MV test was completed within 4 months of 2 GH stim tests).

My husband and I along with the alternative NP did a telephone consult with

Meridian Valley Lab and they had no explanation for how someone could have gh

stimulation test results which show he is gh def., but then on a urine test show

his gh is in range. Meridian Valley suggested that we have his

neurotransmitters tested and minerals tested as well.

I am totally freaking out tonight as my son has been on gh 2 months (finally got

insurance to approve it) and the labs we received today show he is insulin

resistant. He receives .30 mg of gh nightly. 5/3/10 lab results: hemoglobin A1C

is 5.8 (high); triglycerides are high (as usual); insulin is 72.1 (high); and

C-peptide is 7.4 (high). The NP hand wrote on lab " very insulin resistant. "

My questions:

1. Any ideas as to why 2 stimulation tests shows he is gh def. and urine test

results show gh in range? Could this have anything to do with the hg poisoning?

2. Should I stop the gh?

As always, thank you so very much-

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