Humira and enbrel

[Guest guest]

Hi all...

I took Enbrel first and was very satisfied with that medication. I had to mix it myself when first prescribed. Then, i started to get mouth sores. My rheumy took me off the enbrel. Since then, i have had all my teeth removed ( thanks to Sjogrens disease, etc) and have dentures. I feel that i could give the enbrel another try since i am not having problems with my mouth anymore. I will ask to have the enbrel that I mix myself since the premix burns like heck. I also tried Humira which gave me a bad allergic reaction..burning that didn't stop....red and black and blue area at the injection site and hardness. I developed a pressure ulcer from the scab that developed on the injection site that I had to go to wound care center for 3 months to get it taken care of. With the humira burning, i couldn't sleep and had my leg outside the covers with ceiling fan blowing on it. My rheumy told me to use benaryl before my shot and that would take care of the reaction but it didn't. I contacted the Humira site...Abbott... and made my complaint ...also the FDA. It was horrible. It took weeks for the burning to go away. I believe it is the premix only that gave me the problems.

Hopefully, no one else will experience this.

Hugs..paula

[Guest guest]

I had a similar experience with Humira. So I stopped it. Now my new rheummy

is talking about it again. I refused to take it. The burning was horrible. It

was getting longer and longer.

I tried Enbrel and it did not work well for me. But if he insists I will

have to try to try it again. I will NOT take the Humira or even try the pre-mix

Enbrel. The really sad part was when I posted how bad it burned. I got bashed

that the burning was better than the pain of RA. Hmmmmm...I am thinking

this people are crazy and they have no idea what is like to inject burning acid

into your skin...cause that is what if felt like.

I am glad someone else understands..

Toni

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[Guest guest]

That's terrible, a. I'm really sorry you experienced that and

lost a chunk of your leg, too.

It's so important that these side effects are reported. Good that you

did that.

It does seem to be true that, in our group, members generally have a

harder time tolerating the premixed formulations, especially Humira.

Good luck with Enbrel. I hope it's smooth sailing from now on.

Not an MD

>

> I had a bad allergic reaction to the Humira. I was able to take if

for about

> 2 months and the burning would go away after a few minutes. BUT

after taking

> it for about 2 months, I had a very bad reaction...the burning did

not stop.

> It stayed with me..didn't go away. I couldn't even put pants on

or a

> bedsheet over my leg, it hurt so bad. I had to have the ceiling

fan on the whole

> time to cool off my leg. I called the rheumy and he suggested that

I take

> benadryl before my next injection.....the next injection burnt and

stayed with me

> again, was bad but not AS bad. The bad injection site ended up

causing a

> decubitis ulcer (bedsore..pressure sore) on my upper leg. It took

out part of my

> muscle and now there is a indentation in my leg. I ended up having

to go to the

> wound care center for it and had to pack it for about 2 months to

get it

> healed. I did file a report with Abbot and the FDA.

>

> I ended up going with Enbrel. I now use the enbrel self mix...and

inject

> myself 25 mg 2x a week. I believe the premix with the Humira

caused the burn and

> reaction. The premix Humira contains a caustic soda which is a

caustic

> metallic base acid (sodium hydroxide) NaOH which I think may be a

cause of the burn

> and reaction I had. I decided then to go to the enbrel which

doesn't contain

> it.. I have the ingredients printed out for my rheumy to see and

gave them to

> him to see the difference. I printed out the Enbrel premix and it

does not

> contain the sodium hydroxide so I may be okay with it but decided

not to even

> try it since I have had a good result with the premix. If it ain't

broke,

> don't fix it.

>

> That is just my experience with Humira and I am probably only a

very small

> percent since I know others on it and they are doing fine with it.

>

> The Enbrel has always helped me more than the Humira though. I

feel much

> better using the Enbrel. I am also on 5 mg prednisone and 10 mg

arava.

>

> Hope this helps some.

>

> I just wanted to let you know my experience with the Humira. I am

58 and

> have been on so many meds for arth since i was dx'd in 1983.

>

> Hugs..a

[Guest guest]

I TRIED HUMIRA,BUT GOT SEVERE HEADACHES THAT NEVER STOPPED

I CALLED MY RHEUMMY,HE SAID ITS NOT FROM HUMIRA,I STOPPED HUMIRA HEADACHES

WENT AWAY.TOLD MY RHEUMMY HE SAID OH.I WAS ON ENBREL FOR 5 YEARS

IT WORKED WELL,THEN IT STOPPED WORKING,THATS WHY I WENT ON HUMIRA,

NOW I'M BACK ON ENBREL AGAIN,A LITTLE RELIEF IS BETTER THEN NO RELIEF,

I HAVE NO SIDE AFFECTS FROM ENBREL,JUST WHEN I INJECT MYSELF IT BURNS

ANN NJ

aclavern33@... wrote:

I had a similar experience with Humira. So I stopped it. Now my new

rheummy

is talking about it again. I refused to take it. The burning was horrible. It

was getting longer and longer.

I tried Enbrel and it did not work well for me. But if he insists I will

have to try to try it again. I will NOT take the Humira or even try the pre-mix

Enbrel. The really sad part was when I posted how bad it burned. I got bashed

that the burning was better than the pain of RA. Hmmmmm...I am thinking

this people are crazy and they have no idea what is like to inject burning acid

into your skin...cause that is what if felt like.

I am glad someone else understands..

Toni

************************************** Get a sneak peek of the all-new AOL at

http://discover.aol.com/memed/aolcom30tour