Guest guest Posted May 1, 2010 Report Share Posted May 1, 2010 As someone who carries this gene mutation and has ason on the spectrum i know about this and the homocysteine issues,could this be the genetic connection? they talk about the mutationin the sence it causesblood clotting but they treat it with B12 and B2 and folic acid. Crystal NY > > There are 5 types of B 12 > B12 (cobalamin) is a vitamin “family†with five unique family members that each do different things: a) cyanocobalamin; hydroxycobalamin; c) adenosylcobalamin; d) glutathionylcobalamin; e) methylcobalamin. Out of the B12 family, only Methyl-B12 has the ability to activate the methionine/homocysteine biochemical pathway directly. It is this pathway that is responsible for the body’s entire sulfur-based detoxification system. > The most common form of dietary B12 is cyanocobalamin. This is mainly found in meat products. This variety is found only in certain vegetable sources like spirulina. Therefore, vegetarians are more susceptible to a dietary deficiency of B12.While cyanocobalamin form of vitamin B12 works well to prevent anemia, it is the methylcobalamin form that is required to maintain neurological health.Methylcobalamin is the active co-enzyme form of B12 and is the only type present in the brain and central nervous system required for transporting the vitally important methyl groups to proteins in the myelin sheath surrounding nerves.The liver naturally converts a small amount of cyanocobalamin into methylcobalamin, but to regenerate neurons and the myelin sheath that protects axons and peripheral nerves, higher doses of methylcobalamin are necessary. Therefore, for healthy nervous system development additional methylcobalamin is advocated.Most vitamin B12 > (cyanocobalamin and methylcobalamin) are derived from meat products, and meat eaters are rarely lack of dietary B12.Methylcobalamin form is crucial in the treatment of autism. Higher dosages may be required and be given by injection. There is no known toxicity effect. > > Vitamin B12 supplements are not well absorbed orally. 94% of children have been found to respond to Methyl-B12 therapy. Executive function is improved in 90% of children things like awareness, cognition, appropriateness, eye contact when called, and “just being more like a normal kid.†Speech and language is improved in 80% of children all phases including spontaneous language, more complex sentences, increased vocabulary, etc. Socialization and emotion is improved in 70% of the children initiation and interactive play, understanding and feeling emotions, possibly for the first time or to a much more normal degree, etc. > Total dose 85% of children 64.5 mcg/kg/every 3 days works well. > > 35 pounds x 64.5 mcg every 3 days no less than 18 to 24 months of treatment is the protocol. first 5 weeks of Methyl-B12 use must allow absolutely no additions and allow absolutely no deletions to the child’s current program. You need to order through a compounding pharmacy. I am using B-12 methylcobalamin powder Kirkman but next week we are start with the shots. > > > > ________________________________ > De: dmniemes <dmniemes@...> > Para: > Enviado: vie, abril 30, 2010 4:13:44 PM > Asunto: [ ] Methylcobalamin B12 1000mcg > > > We found this at the health food store today and was wondering if anyone can tell me what it's best used for and how much is recommended for a 22 month old, 35 pounds child? > > Thank you in advance:) > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 1, 2010 Report Share Posted May 1, 2010 Good morning, We did the Yasko testing Nutrigenomic. This test tested the genes related to the methylation cycle. We have good information now for my son to address his ammonia, BH$ deficiency, glutathione levels, and methylation. http://www.knowyourgenetics.com/Welcome.html http://www.knowyourgenetics.com/The%20Methylation%20Pathway.html Just another perspective. I am still keeping with all my other treatments and with this information tailor the supplements to get my son's methylation pathways working to increase glutathione and decrease ammonia. Hope this helps. Jerry > > > > There are 5 types of B 12 > > B12 (cobalamin) is a vitamin “family†with five unique family members that each do different things: a) cyanocobalamin; hydroxycobalamin; c) adenosylcobalamin; d) glutathionylcobalamin; e) methylcobalamin. Out of the B12 family, only Methyl-B12 has the ability to activate the methionine/homocysteine biochemical pathway directly. It is this pathway that is responsible for the body’s entire sulfur-based detoxification system. > > The most common form of dietary B12 is cyanocobalamin. This is mainly found in meat products. This variety is found only in certain vegetable sources like spirulina. Therefore, vegetarians are more susceptible to a dietary deficiency of B12.While cyanocobalamin form of vitamin B12 works well to prevent anemia, it is the methylcobalamin form that is required to maintain neurological health.Methylcobalamin is the active co-enzyme form of B12 and is the only type present in the brain and central nervous system required for transporting the vitally important methyl groups to proteins in the myelin sheath surrounding nerves.The liver naturally converts a small amount of cyanocobalamin into methylcobalamin, but to regenerate neurons and the myelin sheath that protects axons and peripheral nerves, higher doses of methylcobalamin are necessary. Therefore, for healthy nervous system development additional methylcobalamin is advocated.Most vitamin B12 > > (cyanocobalamin and methylcobalamin) are derived from meat products, and meat eaters are rarely lack of dietary B12.Methylcobalamin form is crucial in the treatment of autism. Higher dosages may be required and be given by injection. There is no known toxicity effect. > > > > Vitamin B12 supplements are not well absorbed orally. 94% of children have been found to respond to Methyl-B12 therapy. Executive function is improved in 90% of children things like awareness, cognition, appropriateness, eye contact when called, and “just being more like a normal kid.†Speech and language is improved in 80% of children all phases including spontaneous language, more complex sentences, increased vocabulary, etc. Socialization and emotion is improved in 70% of the children initiation and interactive play, understanding and feeling emotions, possibly for the first time or to a much more normal degree, etc. > > Total dose 85% of children 64.5 mcg/kg/every 3 days works well. > > > > 35 pounds x 64.5 mcg every 3 days no less than 18 to 24 months of treatment is the protocol. first 5 weeks of Methyl-B12 use must allow absolutely no additions and allow absolutely no deletions to the child’s current program. You need to order through a compounding pharmacy. I am using B-12 methylcobalamin powder Kirkman but next week we are start with the shots. > > > > > > > > ________________________________ > > De: dmniemes <dmniemes@> > > Para: > > Enviado: vie, abril 30, 2010 4:13:44 PM > > Asunto: [ ] Methylcobalamin B12 1000mcg > > > > > > We found this at the health food store today and was wondering if anyone can tell me what it's best used for and how much is recommended for a 22 month old, 35 pounds child? > > > > Thank you in advance:) > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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