Guest guest Posted May 30, 2006 Report Share Posted May 30, 2006 And here's one from Hopkins linking chronic pain and depression: http://www.hopkins-arthritis.som.jhmi.edu/mngmnt/depression.html (this article also discusses the analgesic affects of antidepressants. OK, I'll stop now, but I did want to point out that what you are feeling is as PHYSICAL as psychological and can be treated medically as well as by talking and dealing with it!) A biological vulnerability to affective disorder in patients with chronic pain is also supported by studies of biological markers. Decreased REM latency, decreased serum melatonin and lower density of 3H-imipramine binding sites on platelets have been found in patients with chronic pain (Blumer et al. 1982; Magni et al. 1987; von Knorring and Ekselius 1994; von Knorring et al. 1983). Depression is not simply a comorbid condition but interacts with chronic pain to increase morbidity and mortality. Depressed chronic pain patients report greater pain intensity, less life control, and more use of passive–avoidant coping strategies. They also describe greater interference from pain and exhibit more pain behaviors than chronic pain patients without depression (Haythornthwaite et al 1991; Herr et al. 1993; Weickgenant 1993). The presence of preoperative depression in patients undergoing lumbar discectomy was predictive of poorer surgical outcome at 1 year follow–up (Junge et al. 1995). In patients with rheumatoid arthritis, depressive symptoms were significantly associated with negative health and functional outcomes as well as increased health services utilization (Katz and Yelin 1993). Quote Link to comment Share on other sites More sharing options...
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