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Why maximum 4.5?

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Hi all, I'm new to this forum and to LDN. I have RRMS, diagnosed in 2004 and

have been on Rebif and Plaquenil for five years. I started 3.0 mg. LDN last

month. Only side effect was headache and irritability for a few days, marked

enough that after two very grumpy days I opened several of my capsules and

tipped out about a third to reduce my dose for three days. After that, 3 mg was

fine, but I never felt much improvement; numbness and fatigue were pretty much

the same. Then last week I accidentally doubled my 3 mg. dose forgetting which

pills were in my tray. The next day I felt like a whole new person. I tried

that again last night and felt like a zombie til this afternoon.

Please tell me why 4.5 is the maximum recommended dose, and who, if anyone, goes

higher.

--Steph

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