WebMD Link Sent By A Friend

March 24, 2008

this article discusses the shingles vaccine it was developed to use only in

adults 60 years and older.

nancie

--------------------------------------------------

From: <deifspirit@...>

Sent: Monday, March 24, 2008 7:37 PM

<deifspirit@...>

Subject: WebMD Link Sent By A Friend

> nancie barnett recently visited WebMD and thought that you would be

> interested in the information below.

>

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>

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> INFORMATION FROM WEBMD

>

> FDA Approves Shingles Vaccine

>

http://www.webmd.com/skin-problems-and-treatments/Shingles/news/20060526/fda-app\

roves-shingles-vaccine

>

> To view, click on the address above or copy and paste it into your Web

> browser.

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March 25, 2008

I am in that age group. What kind of results have they gotten from this vaccine?

Have they

had any negative physical reactions, like allergy?

Roni

nancie barnett <deifspirit@...> wrote:

this article discusses the shingles vaccine it was developed to use only in

adults 60 years and older.

nancie

--------------------------------------------------

From:

Sent: Monday, March 24, 2008 7:37 PM

To:

Subject: WebMD Link Sent By A Friend

> nancie barnett recently visited WebMD and thought that you would be

> interested in the information below.

>

________________________________________________________________________________\

_______________________

>

________________________________________________________________________________\

_______________________

>

> INFORMATION FROM WEBMD

>

> FDA Approves Shingles Vaccine

>

http://www.webmd.com/skin-problems-and-treatments/Shingles/news/20060526/fda-app\

roves-shingles-vaccine

>

> To view, click on the address above or copy and paste it into your Web

> browser.

>

________________________________________________________________________________\

_______________________

>

> LEARN MORE AT WEBMD - the nation's most trusted health and wellness

> resource. http://www.webmd.com/

>

> WebMD's Most Popular Features & Resources

> . Symptom Checker: http://symptoms.webmd.com/

> . Search WebMD: http://www.webmd.com/search/

> . Drug Information: http://www.webmd.com/drugs/index-drugs.aspx

> . Health Video Library:

> http://www.webmd.com/a-to-z-guides/videos/default.htm

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>

> WebMD is committed to your privacy. For more information please visit -

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>

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> WebMD Inc., c/o WebMD Office of Privacy, 1175 Peachtree Street, Suite

> 2400, 100 Colony Square, Atlanta, GA 30361

>

> WebMD provides this " Email a Friend " service as a convenience for you to

> send and receive links to content on our site. It is not intended to

> encourage or promote SPAM in any way. Your email address will only be used

> for the sole purpose of facilitating this email communication and will not

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>

------------------------------------

March 25, 2008

The agency cleared the vaccine -- known as Zostavax -- for use in adults age 60

and older: studies showed it can prevent shingles roughly half the time.

But experts say they're worried that partial insurance coverage of the vaccine

may slow its acceptance by doctors and patients.

Shingles causes a rash with blisters that usually lasts for two to four weeks.

The pain associated with the blisters can be quite intense. Once this initial

phase is over, nerve pain called postherpetic neuralgia can set in. This pain

lasts anywhere from 30 days to months or even years. It can be so severe in some

people that it disrupts their lives.

The illness is caused by varicella, the same virus that causes chickenpox.

Shingles occurs when the chickenpox virus lying dormant in nerve cells " wakes

up " in older people or others with health problems. The vaccine, Zostavax, is

actually a boosted dose of the chickenpox vaccine currently given to children.

Postherpetic neuralgia is more common in people older than 60. It occurs in less

than 10% of people younger than 60 after a bout of shingles but in more than 40%

of people older than 60.

Large Market for Vaccine

There are approximately 50 million Americans over age 60: more than 95% had

chickenpox as children, making them vulnerable to shingles.

" The market is large, " says Fanelle, a spokeswoman for Merck & Co.,

the vaccine's manufacturer.

The company originally sought approval to sell the vaccine to adults 50 and

older. But the FDA declined after expert advisors said in December 2005 that

Zostavax hadn't been studied in patients younger than 60. The agency also

rejected a bid to approve the vaccine for preventing postherpetic neuralgia.

Up to one in ten older patients won't be candidates for the vaccine because of

weakened immune systems due to cancer therapy, organ transplants, HIV/AIDS, or

other causes. The vaccine contains live but weakened varicella virus that could

overwhelm the immune systems of those patients.

Markovitz, MD, a professor of internal medicine at the University of

Michigan who reviewed Zostavax for the FDA, calls it a " highly useful " vaccine.

" It's clear the vaccine markedly reduces the incidence " of shingles, he says.

Markovitz says that doctors may be tempted to offer " off-label " vaccinations to

adults age 50 to 59 in hopes of providing earlier protection against shingles.

" Off-label " refers to drugs that are used in ways that have not been not

approved by the FDA. But he stressed that the vaccine remains unstudied in such

patients and that researchers still don't know how long immunity lasts after

vaccination.

" I don't think I would rush out and get it myself, " Markovitz, who is 52, tells

WebMD.

Insurance Coverage Worries

Other experts worried about the vaccine's cost. Zostavax is slated for coverage

under Medicare's Part D prescription program. But under the program, individual

private insurance plans set prices, meaning that coverage for the vaccine could

vary substantially among hundreds of plans nationwide.

Medicare and private insurers often base coverage decisions on counsel from the

Advisory Committee on Immunization Practices (ACIP) at the CDC.

The committee is expected to make recommendations next fall advising the

government, insurers, and doctors, on how many older Americans should receive

the shingles vaccine.

Insurance coverage inside and outside of Medicare could have a large impact on

how many adults seek the vaccine. " We certainly think that's very important, "

Fanelle says.

Schaffner, MD, chair of the department of preventative medicine at

Vanderbilt University and an ACIP member, says that partial insurance coverage

could impede lower-income people from purchasing the vaccine and limit its

spread among patients who could benefit.

" Many of us are distressed about that possibility, " notes Schaffner, who says he

received financial payment from Merck to discuss Zostavax with reporters.

Follow-Up Study

The company followed patients in its study for four years. Officials told the

FDA that they plan to follow patients for 10 years to determine how long

patients retain immunity before requiring boosters. The company is also planning

to study the vaccine in immunocompromised patients, officials said in December.

Markovitz says the company's original study focused on whites and that the

company should also expand testing in minorities, who can have varying immune

responses.

" Realistically, we can say this works in white people, and it's just too bad

this continues to happen in every darn study, " he said.

roni-

so, what the results show is that it is only effective 50% of the time and it

is more effective in Caucasians. the vaccine is so new that we are not sure of

the effectiveness- it is basically if you are predisposed to having shingles

then it might be worth it to try the vaccine, but only if you have a healthy

immune system. the vaccine is still so new and all the studies have not been

done on all the population groups, so I believe the jury is still out.

personally, I am not sure I would get the vaccine,.

nancie.

From: Roni Molin

Sent: Tuesday, March 25, 2008 8:22 AM

hypothyroidism

Subject: Re: Fw: WebMD Link Sent By A Friend

I am in that age group. What kind of results have they gotten from this vaccine?

Have they

had any negative physical reactions, like allergy?

Roni

nancie barnett <deifspirit@...> wrote:

this article discusses the shingles vaccine it was developed to use only in

adults 60 years and older.

nancie

>

..

May 14, 2008

I really needed this information too. Thanks for providing it.

and Kaylee, 5 poly, uveitis, osteopenia and DBD

WebMD Link Sent By A Friend

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September 2, 2009

[low dose naltrexone] WebMD Link Sent By A Friendlow dose naltrexone Date: Tuesday, September 1, 2009, 11:05 PM

karen recently visited WebMD and thought that you would be interested in the information below. Here is a personal message for you._______________________________________________________________________________________________________PERSONAL MESSAGE : I'm confused...should it be used with ldn? Aren't there different kinds of vit D?_______________________________________________________________________________________________________INFORMATION FROM WEBMDHigh Doses of Vitamin D Cut MS Relapseshttp://www.webmd.com/mental-health/news/20090428/high-doses-vitamin-d-cut-ms-relapsesTo view, click on the address above or copy and paste it into your Web browser._______________________________________________________________________________________________________LEARN MORE AT WEBMD - the nation's most trusted health and wellness resource. http://www.webmd.com/WebMD's Most Popular Features & Resources. Symptom Checker: http://symptoms.webmd.com/. Search WebMD: http://www.webmd.com/search/. Drug Information: http://www.webmd.com/drugs/index-drugs.aspx. Health Video Library: http://www.webmd.com/a-to-z-guides/videos/default.htm. Find a Doctor: http://doctor.webmd.com/. Personal Health Manager: http://www.webmd.com/health-manager. Free Newsletters: http://newsletter.webmd.comWebMD is committed to your privacy. For more information please visit - http://www.webmd.com/policies/about-privacy-policy WebMD's Address:WebMD Inc., c/o WebMD Office of Privacy, 1175 Peachtree Street, Suite 2400, 100 Colony Square, Atlanta, GA 30361WebMD provides this "Email a Friend" service as a convenience for you to send and receive links to content on our site. It is not intended to encourage or promote SPAM in any way. Your email address will only be used for the sole purpose of facilitating this email communication and will not be used for any other purpose. WebMD does not validate the authenticity of the sender's email address or identity.© 2007 WebMD, Inc. All rights reserved.WebMD does not provide medical advice, diagnosis or treatment.------------------------------------