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,

You wrote:

>... Now, it makes no sense at all to me why my tsh would be so high (32+,

>indicating it was trying so hard to produce hormones, right?), and then my

>Free Throxine would be " normal " (1.0 ng/dL) according to the " lab normal "

>standards of .8-1.5. (My doc actually noted that 1.0 was low, but I don't

>see how that's the case...).

>

Perhaps the " lab normal " reading was lower than would be expected under

the circumstance of your having just taken the supplement. The normal

(or natural) range is based on healthy, untreated subjects, not someone

taking that specific medication, in which case concentrations would peak

about an hour after taking it, and then would gradually decrease through

the day or night until the next dose. On the other hand, if you had been

taking the supplement regularly for awhile and the blood test was done

right before taking a dose, then his note might have meant that he

expected it to be low, but was surprised to see that it wasn't.

Be sure to ask him what he meant. All we can do is guess.

The elevation of TSH is a function of both reduced levels of various

thyroid hormones and the TIME those hormones have been missing. TSH

keeps creeping up the longer the condition persists without the desired

response. That is why TSH level is not proportional to how badly you

feel. It is more like a complicated product of degree of illness and the

time you have felt that way.

One part of this is that T3 and the other hormones that affect TSH can

only go so low. Concentration cannot go negative. So, the pituitary

responds to a drop with a little TSH. If that doesn't work, it tries a

little harder, and so on. Consequently, a TSH of 8 can be associated

with symptoms just as bad as those with a TSH of 32. The 32 just

indicates longer suffering. The tricky part in using TSH for titration

is finding where the crossover to feeling well again is. For some, a TSH

of 1.0 may be fine. For others, 0.1 is still too high. I start feeling

pretty miserable above 3.0.

Chuck

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,

You wrote:

>... Now, it makes no sense at all to me why my tsh would be so high (32+,

>indicating it was trying so hard to produce hormones, right?), and then my

>Free Throxine would be " normal " (1.0 ng/dL) according to the " lab normal "

>standards of .8-1.5. (My doc actually noted that 1.0 was low, but I don't

>see how that's the case...).

>

Perhaps the " lab normal " reading was lower than would be expected under

the circumstance of your having just taken the supplement. The normal

(or natural) range is based on healthy, untreated subjects, not someone

taking that specific medication, in which case concentrations would peak

about an hour after taking it, and then would gradually decrease through

the day or night until the next dose. On the other hand, if you had been

taking the supplement regularly for awhile and the blood test was done

right before taking a dose, then his note might have meant that he

expected it to be low, but was surprised to see that it wasn't.

Be sure to ask him what he meant. All we can do is guess.

The elevation of TSH is a function of both reduced levels of various

thyroid hormones and the TIME those hormones have been missing. TSH

keeps creeping up the longer the condition persists without the desired

response. That is why TSH level is not proportional to how badly you

feel. It is more like a complicated product of degree of illness and the

time you have felt that way.

One part of this is that T3 and the other hormones that affect TSH can

only go so low. Concentration cannot go negative. So, the pituitary

responds to a drop with a little TSH. If that doesn't work, it tries a

little harder, and so on. Consequently, a TSH of 8 can be associated

with symptoms just as bad as those with a TSH of 32. The 32 just

indicates longer suffering. The tricky part in using TSH for titration

is finding where the crossover to feeling well again is. For some, a TSH

of 1.0 may be fine. For others, 0.1 is still too high. I start feeling

pretty miserable above 3.0.

Chuck

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