Guest guest Posted April 28, 2000 Report Share Posted April 28, 2000 http://abcnews.go.com/sections/living/SecondOpinion/mail_secondopinion ..html Write to Rush and give him ideas for new stories. Do you disagree with Regush on this issue? Would you like to give him a compliment, or story tip? He's eager to know what you think ____________________________ http://abcnews.go.com/sections/living/SecondOpinion/secondopinion_72.h tml Chronic Parasite Syndrome? Tiny Worms May Explain Mysterious Disease Commentary By Regush What next? Medical research is full of intriguing surprises - if you keep an open mind and can somehow prevent your vested interests from spoiling all the fun. It's been my experience that much of what we think we know about disease is a microscopic fragment of what we really need to know before we decide to get all huffy and puffy and full of ourselves. Take chronic fatigue syndrome, a collection of symptoms including fatigue, malaise, memory problems, painful muscles and joints and so on. To this day, there are a bunch of scientific know-it-alls at the National Institutes of Health who continue to insist CFS is an all-in-the-mind disease. Good grief! Have they no imagination? Do they need special counseling? Does the American Psychiatric Association have an intimidating dossier on them? Well, here's one of those fun scientific surprises for the imagination-deprived. It's an account from California (I know what you 're thinking, so stop) that suggests a novel contributor to CFS. It's a parasite. What? Surely I jest. The all-in-the-mind camp reading this is hysterical, no doubt. No, this one's for real, or at the very least we should give it a fair hearing. It turns out that what looks like a new type of roundworm (named cryptostrongylus pulmoni) has been identified in the sputum of CFS patients and not in control subjects. This comes from a very small study conducted by parasite expert Lawrence Kaplow, who knows full well that he needs more research data before anyone really takes this seriously. This all started when Kaplow followed up on a case of a CFS patient who had strange body rashes. With some difficulty (because the parasite is not King Kong; it's less than a millimeter long), he managed to flesh it out in sputum - mainly bits and pieces of it, such as mouth parts and genitals. (Ugh! Is this why the psychogenically-challenged NIH crowd avoids discussion of the body parts of CFS patients and focuses on the so-called mind?) Casualties of War? Kaplow used an imaging system which allowed him to twirl the worm specimens around for detailed examination. That's when he was able to determine that the parasite had anatomical features that were related to roundworms found in the jungles of Southeast Asia. Did soldiers returning from the Vietnam War bring these roundworms to the U.S.? Maybe, because there is some history about how soldiers bring back parasitic infections from far-off war zones. So does this mean that these roundworms are passed on from person to person? Kaplow thinks not because he has not identified a stage of the parasite in sputum that would suggest casual transmission. The samples he has fished out have emerged in various states of decay. So how do people become infected? Kaplow suggests the parasite may be found in food because that's typically how roundworms are contracted. And because the parasite appears to take its time reproducing, Kaplow sees a possible relationship between outbreaks of CFS that continue over several months and even years. Imagine, a food-borne infection possibly involved in CFS. I find it fascinating that this tiny bit of research also points to the possibility that this type of roundworm infection affects a person's immune system. Roundworm infections are known to be associated with immune abnormalities, such as low serum cortisol (a steroid hormone produced by the body), altered anti-viral responses, and changes in certain white blood cells. Once there is any assault on the immune system, chronic microbes hanging out in the body - such as herpes viruses - may awaken and get involved in the attack. CFS research certainly suggests a strong viral input. So, what do we make of this? Well, we obviously need more research in this area. Disease is complex and science has to be on its toes. Otherwise, it will dig itself a big ditch - much like the all-in-the-mind crowd has done in its piffle of effort to understand CFS. Regush produces medical features for ABCNEWS. In his weekly column, published Wednesdays, he looks at medical trouble spots, heralds innovative achievements and analyzes health trends that may greatly influence our lives. His latest book is The Breaking Point: Understanding Your Potential for Violence; go here to preview his new book, The Virus Within: A Coming Epidemic. Quote Link to comment Share on other sites More sharing options...
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