methotrexate and leg weakness

[Guest guest]

Hi,

I am new to this group. I've had psoriasis for approximately 8 years

and finally a dermatologist in Manhattan has cleared up my areas

through monitoring methotrexate and an Humira injection every 2 weeks.

However, now I am experiencing burning sensation in my lower

extremities along with weakness. I have an appt with a rheumatologist

next week, who hopefully can get me straightened out.

Any suggestions?

Thanks,

Doris

[Guest guest]

I think some of us have had burning due to Enbrel or Humira. I myself

was just hospitalized with extreme weakness and sensations in my legs.

You might want to call your Rheumy and ask if he/she thinks you should

discontinue the Humira until you are seen.....just in case. I hesitate

to say anything to you because I feel it is very important for us to

take caution and not attempt to " diagnose " each other. Sounds so

familiar to me though. Can you go to a drug store and check your blood

pressure to see if it's lower than usual? This seems to be what caused

my weakness and then dizziness when I stand up. What caused the blood

pressure drop is unanswered at this point but the Enbrel I was on is

suspected so I am off of that and will be starting a new IV medication

approved for RA called Orencia as soon as we determine that my Blood

pressure medication is well established and not going to cause

problems. For the record, I still think that Enbrel and Humira are

fabulous drugs who have helped many people get their lives back. I had

two amazing months or normalacy on Enbrel. It just did not work out for

me in the long run. One of the problems with these drugs can be the

getting on it and off of it as infections occur. This shocks our bodies

and it seems to be better to stay on it if you can rather than get off

of it with every little sniffle. It's all pretty tricky but most things

are that effect your life so greatly. I hope this helped you some. Feel

free to contact me with more questions if you have them. I'd like to

wekcome you to the group but I'm sorry you had need to find us. This

group has been my rock. Hoping that you are able to find solace here as

well. -Betz

>

> Hi,

> I am new to this group. I've had psoriasis for approximately 8 years

> and finally a dermatologist in Manhattan has cleared up my areas

> through monitoring methotrexate and an Humira injection every 2 weeks.

> However, now I am experiencing burning sensation in my lower

> extremities along with weakness. I have an appt with a rheumatologist

> next week, who hopefully can get me straightened out.

> Any suggestions?

> Thanks,

> Doris

>

[Guest guest]

Welcome, Doris. Your post caught my eye because you mention leg

weakness with Humira. My rheumy is considering adding Humira to my

mix of meds and just this a.m. gave me some literature on it to read.

I notice that weakness in the legs is one possible side effect of

Humira indicating a possible effect on the nervous system. I wouldn't

panic, but I would let my rheumy or derm know about this development

right away. Probably not serious, but always best to err on the side

of caution.

best regards,

sherry z

>

> Hi,

> I am new to this group. I've had psoriasis for approximately 8 years

> and finally a dermatologist in Manhattan has cleared up my areas

> through monitoring methotrexate and an Humira injection every 2

weeks.

> However, now I am experiencing burning sensation in my lower

> extremities along with weakness. I have an appt with a rheumatologist

> next week, who hopefully can get me straightened out.

> Any suggestions?

> Thanks,

> Doris

>

[Guest guest]

In a message dated 20/10/2006 12:41:25 GMT Standard Time,

premanolita25@... writes:

I am new to this group. I've had psoriasis for approximately 8 years

and finally a dermatologist in Manhattan has cleared up my areas

through monitoring methotrexate and an Humira injection every 2 weeks.

However, now I am experiencing burning sensation in my lower

extremities along with weakness. I have an appt with a rheumatologist

next week, who hopefully can get me straightened out.

Any suggestions?

Thanks,

Doris

Hi Doris,

Welcome to the group. I hope the Rheumy has been able to help you in some

way. This is a great group you have joined, full of knowledgeable and caring

people.

Just read on and see you will be starting Remicade. I hope it works really

well for you.

Good luck,