Guest guest Posted November 9, 2007 Report Share Posted November 9, 2007 I have been on Enbrel shots for 2 weeks now and also on 20mg of methotrexate and 10mg a day of prednisone. HOW LONG does it take for the Enbrel to kick? My ankles are horrible and I have a stand up job. I can only do about 4 hours at the most right now and am in horrible pain the entire time.I wear ankle supports but things aren't improving. Quote Link to comment Share on other sites More sharing options...
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