Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 I compounded my own DMSA/ALA caps and I used milk thistle as the filler as the only size caps I could use was 0. Each cap has 350 mg of milk thistle. Is this too much milk thistle since I'll be giving a cap every 3 hours? I know that milk thistle in extremely high doses can affect the half life of drugs but I don't know what the threshold is. Cheryl ~http://www.gryffins-tail.blogspot.com ~@midian42~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 Hi Cheryl, The dosage does seem high to me, but then to my knowledge, milk thistle isn't harmful in high amounts. In our house, I base the dosage of milk thistle on stool colour & consistency and bowel movements/intestinal upset. When the dosage is too low, we have lighter stool and constipation; too high and there is diarrhea or gas & intestinal upset. I give 150 mg of milk thistle with meals outside of rounds and more during rounds. I had to more than double the amount for two of my kids because their stool gets much lighter on rounds which is a sign of reduced bile flow. I didn't know that very high milk thistle affects the half-life of drugs. Can you point me to more info about that? Have you used milk thistle before? If not, then I suggest starting at a lower amount & I also recommend using it outside the round to see the differences on rounds. HTH, > > I compounded my own DMSA/ALA caps and I used milk thistle as the > filler as the only size caps I could use was 0. Each cap has 350 mg > of milk thistle. Is this too much milk thistle since I'll be giving a > cap every 3 hours? I know that milk thistle in extremely high doses > can affect the half life of drugs but I don't know what the threshold > is. > > Cheryl Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 That's about a daily dose for most kids. We give our kids 300mg a day, spread out throughout the day. I believe the recommended dose is 250mg per day spread out. I would find some other edible powder to compound with. TJ ________________________________ From: Cheryl Lowrance <cheryl.lowrance@...> Sent: Fri, November 6, 2009 7:36:02 AM Subject: [ ] When have you reached too much Milk Thistle? Â I compounded my own DMSA/ALA caps and I used milk thistle as the filler as the only size caps I could use was 0. Each cap has 350 mg of milk thistle. Is this too much milk thistle since I'll be giving a cap every 3 hours? I know that milk thistle in extremely high doses can affect the half life of drugs but I don't know what the threshold is. Cheryl ~http://www.gryffins -tail.blogspot. com ~@midian42~ Quote Link to comment Share on other sites More sharing options...
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