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L-Tryptophan

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I have used trypto from almost the beginning of my full-time illness in the late

'70's. It is a mainstay of my protocol. There was a year or so when I could not

get it, and life got much worse-and the 5 hydroxy form barely made up the

difference.

I have ben buying it for many years now from biochemicals.com. (You can get

their 800# there.) They sell it as a veterinary product.

If you prefer to spend more money, this firm requires a prescription-but not

necessarily from an MD. Apothecure: 800-969-6601.

I encourage anyone with sleep difficulties to try it. When I use it, ti actually

shortens my sleep- but I awaken much more refreshed and mentally organized and

clear.

Adrienne

L-Tryptophan

Hi all,

Quick question for the group. Has anyone had an experience using l-tryptophan?

Good? Bad? Also, where can you get it?

Melinda

Melinda Kaufman

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Yes I tried L-tryptophan for sleep and it didn't help - just made me feel

strange

sorry I can't remember the site I bought it from but a member of this list

posted it - it was a vetinary supplies site

L-Tryptophan

> Hi all,

>

> Quick question for the group. Has anyone had an experience using

l-tryptophan? Good? Bad? Also, where can you get it?

>

> Melinda

>

> Melinda Kaufman

>

>

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  • 1 year later...
Guest guest

Hi all,

I thought I'd read that L-tryptophan was 'newly' available again with

out RX for human use recently. . .

Did a quick google search, this APPEARS to be L-tryptophan available

without RX and for human use (not vet), as best as I can tell:

http://www.iherb.com/bestltrypto.html

V

> > > > > Hi, all.

> > > > >

> > > > > As you may know, a subset of PWCs find benefits from taking

> > > NADH.

> > > > > This has always been a curious fact to me, because

available

> > > > > evidence in the literature suggests that this molecule is

> > broken

> > > > > down in the gut, so that the most significant absorbed

> species

> > > from

> > > > > taking NADH is niacinamide, which is a form of vitamin B3.

> I

> > > have

> > > > > suggested in the past that perhaps the same benefits could

> be

> > > > gained

> > > > > by these PWCs from simply taking niacinamide, which is less

> > > > > expensive.

> > > > >

> > > > > I've been giving some more thought to this. Niacinamide is

> > used

> > > in

> > > > > the body to reform NADH inside the cells, and this molecule

> is

> > > used

> > > > > to carry energetic electrons from the glycolysis chain and

> the

> > > > Krebs

> > > > > cycle to the respiratory chain, thus helping to produce

ATP,

> > the

> > > > > energy currency of the cell. In the past, I've suggested

> that

> > > this

> > > > > is how taking NADH supplement benefits some PWCs.

> > > > >

> > > > > It has now occurred to me that perhaps another benefit, and

> > > maybe

> > > > > even a more significant benefit, would come from the fact

> that

> > > the

> > > > > body can also use niacinamide to form the amino acid

> > > tryptophan.

> > > > It

> > > > > is known from the work of Bralley and Lord several years

ago

> > > that

> > > > > the amino acid that is most deficient in the blood plasma

of

> > > PWCs

> > > > is

> > > > > tryptophan. Tryptophan is needed to make serotonin and

> > > melatonin,

> > > > > which affect pain sensitivity, sleep and other functions.

> (Some

> > > > PWCs

> > > > > take 5-HTP or 5-hydroxytryptophan, the form that is sold

> over-

> > > the-

> > > > > counter in the U.S., to help build serotonin and melatonin,

> > > > > particularly to improve sleep.)

> > > > >

> > > > > In the past, I have suggested that the low plasma

tryptophan

> > > level

> > > > > is a result of the fact that tryptophan is transported

> across

> > > the

> > > > > blood-brain barrier more rapidly than normal in PWCs,

> because

> > of

> > > > the

> > > > > lack of competition from the branched-chain amino acids,

> which

> > > use

> > > > > the same transporter in the blood-brain barrier, and which

> are

> > > also

> > > > > found to be low in the blood plasma. I have suggested that

> the

> > > > > branched-chain amino acids are low because they are burned

> by

> > > the

> > > > > muscle cells in lieu of being able to burn carbohydrates

and

> > > fats

> > > > > efficiently in the Krebs cycle, due to the partial blockade

> > from

> > > > > peroxynitrite, as a result of glutathione depletion. I

> still

> > > think

> > > > > this is true for many PWCs. Logan and also Werbach

reviewed

> > the

> > > > > evidence for elevated serotonergic effects in CFS, which

> would

> > > be

> > > > > consistent with elevated transport of tryptophan into the

> > brain,

> > > > > since the rate of production of serotonin has been shown to

> be

> > > > > sensitive to the amount of available tryptophan.

> > > > >

> > > > > However, there are some PWCs who don't have elevated

> > > serotonergic

> > > > > activity, and most PWFs don't have it, either. So now I'm

> > > > > suggesting that this subset needs more tryptophan, and one

> way

> > > of

> > > > > supplying it is by supplementing niacinamide, which I

> believe

> > is

> > > > > what taking NADH as a supplement really does.

> > > > >

> > > > > This may sound pretty convoluted, but I think it may be

> true.

> > > The

> > > > > presence of subsets in these disorders complicates things.

> > > > >

> > > > > I guess my bottom line question is to those PWCs who have

> > > noticed

> > > > > benefits from taking NADH: Have you tried just taking

> > > niacinamide

> > > > > (a form of vitamin B3), and if so, have you received the

> same

> > > > > benefits from it?

> > > > >

> > > > > Rich

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Guest guest

That's the one that is labeled for veterinary use. I have used it for many

years. (When my doggie sleeps well, I too sleep so much better!)If you want it

marked for humans, you need a scrip. Hardly likely it is two different products.

Adrienne

Re: Re: L-tryptophan

See the following link for getting tryptophan without a prescription:

http://www.alternativementalhealth.com/articles/tryptophan.htm

wrote:

> Hi all,

> I thought I'd read that L-tryptophan was 'newly' available again with

> out RX for human use recently. . .

>

> Did a quick google search, this APPEARS to be L-tryptophan available

> without RX and for human use (not vet), as best as I can tell:

>

> http://www.iherb.com/bestltrypto.html

>

> V

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

------------------------------------------------------------------------------

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Guest guest

The one I linked to does NOT appear to be for vet use but for human

use as it says it is approved for vegetarians' use -- don't think most

vet formulas specify what is for vegetarian dogs :)

" Best L-Tryptophan, Doctor's Best, 500 mg, 90 Veggie Caps

Label Information:

Best L-Tryptophan, Doctor's Best, 500 mg, 90 Veggie Caps

• USP Pharmaceutical Grade

• Science-Based Nutrition

• Suitable for vegetarians

• Dietary Supplement

L-tryptophan is an essential amino acid (protein building block) in

human nutrition. Essential amino acids are not synthesized by the body

and must be obtained in the diet. The L-tryptophan in this product is

manufactured and tested for purity according to the United States

Pharmacopeia (USP) standards.*

Suggested Use: Take 1 or 2 capsules daily, or as directed by a health

practitioner. For optimum absorption, take separately from

protein-containing foods and dietary supplements containing protein or

amino acids. "

http://www.iherb.com/bestltrypto.html

all the best,

>

> > Hi all,

> > I thought I'd read that L-tryptophan was 'newly' available again

with

> > out RX for human use recently. . .

> >

> > Did a quick google search, this APPEARS to be L-tryptophan available

> > without RX and for human use (not vet), as best as I can tell:

> >

> > http://www.iherb.com/bestltrypto.html

> >

> > V

>

>

>

>

> This list is intended for patients to share personal experiences

with each other, not to give medical advice. If you are interested in

any treatment discussed here, please consult your doctor.

>

>

>

>

------------------------------------------------------------------------------

>

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Guest guest

See the following link for getting tryptophan without a prescription:

http://www.alternativementalhealth.com/articles/tryptophan.htm

wrote:

> Hi all,

> I thought I'd read that L-tryptophan was 'newly' available again with

> out RX for human use recently. . .

>

> Did a quick google search, this APPEARS to be L-tryptophan available

> without RX and for human use (not vet), as best as I can tell:

>

> http://www.iherb.com/bestltrypto.html

>

> V

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  • 8 months later...
Guest guest

Dear Marge, thanks for the information. I'm glad you agree with what

is recommended here.

Bee

Marge wrote:

>

> ==>Wasn't that the l-tryptophan that was tainted by something?

> <snip>

> Yes, it was the tainted L-t. There are theories among the

> researchers who followed those who were injured that there

> were earlier hot batches, just not AS hot as the 1989 batch.

>

> And there is some evidence that L-tryptophan use may have

> caused neuro-psychiatric injuries all along..without being tainted.

>

> Our specialist (one of a handful in the world who studied that

> disaster) has identified cases of the same disease from both

> one of the B vitamins and from L-lysine. In all cases the

incidentsby genetically engineered product. He told us that

> there is no question it will occur again, just where, when and how

> bad.

>

> So you get a better picture as to why I was greatly relieved to

> see you cautious about recommending one particular amino

> acid, and a precaution regarding supplements outside simple and

> naturally occuring ones. That and the good sense regarding

> cleanses have made me comfortable enough to think I can do

> this.

<snip>

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Guest guest

Kudos go out to Drs. Phil Zapf and Bonnie McDowell of Forest Grove who had a feature story on their practice, and the practice of chiropractic in yesterday's Oregonian Business Section for Washington County.....the extra piece that comes out on Thursday. I guess each section of the city has a specific insert for their area. Anyway, I thought it was a good representation of chiropractic.

Congratulations!!

Dr. Don WHite

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Guest guest

Ron,

You can get Hydroxy-tryptophan (5-HTP from NF or TIT) which just has a

hydroxyl group attatched to the amino acid. (Probably made by dipping

turkeys in hydrogen peroxide.)

It has the same action as tryptophan without the lawsuits.

( E. Abrahamson, D.C.)

Chiropractic physician

Lake Oswego Chiropractic Clinic

315 Second Street

Lake Oswego, OR 97034

503-635-6246

Website: http://www.lakeoswegochiro.com

> From: rongrice01 <rongrice@...>

> Date: Fri, 24 Mar 2006 22:15:38 -0000

> < >

> Subject: L-Tryptophan

>

> Docs.

>

> I just received several free samples of L-Tryptophan. I thought this

> had been removed from the market and was only available by

> prescription from an MD.

>

> Anyone have any idea as to the legality of this supplement?

>

> Grice, DC

> Albany, OR

>

>

>

>

>

> OregonDCs rules:

> 1. Keep correspondence professional; the purpose of the listserve is to foster

> communication and collegiality. No personal attacks on listserve members will

> be tolerated.

> 2. Always sign your e-mails with your first and last name.

> 3. The listserve is not secure; your e-mail could end up anywhere. However, it

> is against the rules of the listserve to copy, print, forward, or otherwise

> distribute correspondence written by another member without his or her

> consent, unless all personal identifiers have been removed.

>

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Guest guest

It's probably fine....FDA beholding to the drug Co. banned it because of a

contaminated lot out of Japan.....bottom-line it was competing to much with

the likes of Prozac!

Vern

L-Tryptophan

> Docs.

>

> I just received several free samples of L-Tryptophan. I thought this

> had been removed from the market and was only available by

> prescription from an MD.

>

> Anyone have any idea as to the legality of this supplement?

>

> Grice, DC

> Albany, OR

>

>

>

>

>

> OregonDCs rules:

> 1. Keep correspondence professional; the purpose of the listserve is to

foster communication and collegiality. No personal attacks on listserve

members will be tolerated.

> 2. Always sign your e-mails with your first and last name.

> 3. The listserve is not secure; your e-mail could end up anywhere.

However, it is against the rules of the listserve to copy, print, forward,

or otherwise distribute correspondence written by another member without his

or her consent, unless all personal identifiers have been removed.

>

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  • 4 months later...
Guest guest

It's available again -- has been for a couple years. I think the internet

sellers first had to

say they were selling it for veterinary purposes, but now it's available in most

supplement

stores (like Super Supplements -- they have an online store too). It's pricey

however --

last time I checked it was around $55?

d.

> >

> >

> > (Hey, ! Thanks for prodding me to open that jar of

> > tryptophan I was too tired to bother with before; a spoonful of that

> > before turning in has helped me fall asleep a LOT faster!)

> >

>

>

>

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Guest guest

Beyond-a-century.com has 100 grams (bulk) available for $15 (as of

their printed catalog anyway) (suggested retail $79.99, which tells

you something about mark-ups!).

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Guest guest

Conversion...

100 gram = 3.527 396 195 ounce

http://www.onlineconversion.com/weight.htm

That seems like so little! Powders are " big, " though, right? How do

you take it, may I ask? By the teaspoon, or something else? Can you

figure how many teaspoons or servings are in the container?

>

> Beyond-a-century.com has 100 grams (bulk) available for $15 (as of

> their printed catalog anyway) (suggested retail $79.99, which tells

> you something about mark-ups!).

>

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Guest guest

The usual dose of tryptophan in a cap is 500 mg. I take 2 at bedtime.

I DO NOT think youwant to be taking trypto by the spoonful. Too much serotonin

can cause illness.

Adrienne

Re: L-tryptophan

Conversion...

100 gram = 3.527 396 195 ounce

http://www.onlineconversion.com/weight.htm

That seems like so little! Powders are " big, " though, right? How do

you take it, may I ask? By the teaspoon, or something else? Can you

figure how many teaspoons or servings are in the container?

>

> Beyond-a-century.com has 100 grams (bulk) available for $15 (as of

> their printed catalog anyway) (suggested retail $79.99, which tells

> you something about mark-ups!).

>

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

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Guest guest

Adrienne...can you take it, without using any other Sleep agents, and it

works?!

Amelia

***Absolutely. And it does not lose its effect. I have been on it for, I

think, a decade or so.

Adrienne

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  • 3 months later...

I get mine from iherb link I take anywhere from 500 mg to 2 grams,

depending. Start small and work up. MUST be on an empty stomach to optimize

effectivenss.

_http://www.iherb.com/store/ProductsList.aspx?c=Herbs & cid=l_tryptophan_

(http://www.iherb.com/store/ProductsList.aspx?c=Herbs & cid=l_tryptophan)

Remember, that I also take SAM-e, another amino acid, in the morning on an

empty stomach and Magnesium+B6 three or four times a day.

Hot baths with EPsom salt before bed help the body relax.

You had listed several things that you were taking without giving doseages

or how long you were taking them before you decided they did not help you

sleep.

Posted by: " sb2boys " _sb2boys@... _

(mailto:sb2boys@...?Subject=Re: L-Tryptophan) _sb2boys _

(sb2boys)

Sun Oct 29, 2006 1:12 pm (PST)

Many of you have said that L-Tryptophan helps you fall asleep. Where

do you buy it and how much do you have to take? I have to take quite

a bit of anything I try, for it to help me sleep at all. Thank you!

Sue

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

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Another question--

Is any brand better than another (more pure)? What does the powder

form taste like? Thank you so much for your help!

Sue

>

> Many of you have said that L-Tryptophan helps you fall asleep. Where

> do you buy it and how much do you have to take? I have to take quite

> a bit of anything I try, for it to help me sleep at all. Thank you!

> Sue

>

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At first I didn't need it to fall asleep, and then after I got used to it, I

did. The main thing it does for me is make my sleep more restful. I wake up

clearer and more energetic. I buy it from www.biochemicals.com

I use 500-1000mg.

L-Tryptophan

Many of you have said that L-Tryptophan helps you fall asleep. Where

do you buy it and how much do you have to take? I have to take quite

a bit of anything I try, for it to help me sleep at all. Thank you!

Sue

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

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  • 3 months later...

If you can't get l-tryptophan then just use 5-Hydroxytryptophan

(5-HTP)instead. It's been on the market for several years. You can

read about it at http://en.wikipedia.org/wiki/5-HTP

I used to take l-tryptophan as a sleep aid, but no longer need to do

so. You can read about it at http://en.wikipedia.org/wiki/Tryptophan

Best regards,

Celeste

wrote:

> Years back before it was banned, we used L-Tryptophan for sleep.

> After the ban we switched to melatonin and other herbs.

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On Saturday 24 February 2007 4:16 pm, a1thighmaster wrote:

> If you can't get l-tryptophan then just use 5-Hydroxytryptophan

> (5-HTP)instead. It's been on the market for several years. You can

> read about it at http://en.wikipedia.org/wiki/5-HTP

>

> I used to take l-tryptophan as a sleep aid, but no longer need to do

> so. You can read about it at http://en.wikipedia.org/wiki/Tryptophan

>

> Best regards,

> Celeste

>

> wrote:

> > Years back before it was banned, we used L-Tryptophan for sleep.

> > After the ban we switched to melatonin and other herbs.

L-tryptophan has been available for purchase for at least 8 years because I

was buying it back then sometimes in sizes of 1000 grams of powder. It never

did work as a sleep aid for me but I was using it for other reasons. The FDA

used a manufacturing contamination to remove it from the market just as

Prozac was introduced. Early last year, the FDA finally removed it's

restrictions completely but its been available retail for a long time.

http://froogle.google.com/froogle?hl=en & q=tryptophan & btnG=Search & ie=UTF-8 & oe=UTF\

-8 & um=1 & sa=N & tab=wf

--

Steve - dudescholar3@...

" Man's mind, once stretched by a new idea, never regains its original

dimensions. "

--Oliver Wendell Holmes

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  • 1 year later...

Can LDN be taken with other medications such as tranquilizers or

chemotherapy? How about interactions with alcohol or tobacco?

LDN can be taken along with any other medication or substance, so

long as it is not narcotic-containing. Naltrexone is a pure opioid

antagonist and it will block the action of narcotics. Some examples

of narcotic-containing drugs are Ultram, morphine, Percocet,

Duragesic patch and any codeine-containing medication.

http://www.low dose naltrexone.org/further_q_and_a.htm

Art

---

>

> I'm still waiting for my RX of LDN to arrive, in the meantime, does

anyone know if L-Tryptophan is a good alternative for dealing with

the sleep disturbances. I've used Melatonin when I can't sleep, but L-

Tryptophan seems to work better for me if I take it 20 minutes before

bed on an empty stomach. This may be a question for the chemists out

there. Just wondering if it would interfere with the LDN?

> Thanks,

> Jo

> Prescott, AZ

>

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  • 3 weeks later...

I was wondering if anyone uses anything to help with Jet Lag?

Melatonin doesn't really agree with me- I was wondering if people have

experience with L-Tryp helping with sleeplessness?

Jodi

Can I take this after LDN?

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Jodi...

I am hypothyroid and currently dealing with adrenal fatigue and high

cortisol. I take a number of things to help me sleep. Tryptophan

does help me fall asleep. It doesn't keep me asleep, though. I also

take melatonin, LDN and 25 mgs of elavil. I am currently in the

process of weaning off the elavil.

Lorie

>

> I was wondering if anyone uses anything to help with Jet Lag?

>

> Melatonin doesn't really agree with me- I was wondering if people have

> experience with L-Tryp helping with sleeplessness?

>

> Jodi

>

> Can I take this after LDN?

>

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