Re: Confused about mito dysfunction

[Guest guest]

I'm under the impression that it is the age old curiosity - " which came

first, the chicken or the egg. " Remember when they did the study year

back that alcoholics had altered brains, therefore, alcoholism must be

genetic. But, then, there was a whole different set of research that

said that alcoholism itself is what alters the brain,not the other way

around. A shining example of why I'll take real life experience over

research any day. The obvious mito dys in our family is our NT

daughter. The mito cocktail worked wonders, and we are now chelating.

We have switched to algae pills from the mito cocktail, and I see

obvious signs of improvement since chelation. She also doesn't need

enzymes at every meal any more. So, what I'm wondering is, if mito dys

is genetic, then how in the world is chelation healing it? Hmmmmm. .

.. I was under the impression that the genes don't change. To me

another of those imponderables. I'll just keep chelating and removing

extra supplements and diet changes until she's 100% again. :-) Which,

by the way, I suspect she never has been, since she was terribly fussy

as a baby. I'm thinking, yes, she was born with the problem, but maybe

it was because I was mercury toxic while I carried her, so she just

started out that way. Of course, that would be indication to some

researchers that it was genetic.

P.

kellyjeffmaxmark wrote:

>

> If you have this SNP, SOD2 +/+, which affects

> the mitochondria, is this a genetic predisposition

> for getting Autism? Does the environment alter

> the genes, whether that was with an ancestor or a new

> toxin that overloads the system? And if you eliminate

> the toxins, the genes work better with an improved

> environment?

>

>

[Guest guest]

I think there has always been genetically autstic people in the population but

it was fairly rare 4 in 10,000. When I say genetic autism I mean due to a

inherited defect or deletion in the mitochondrial DNA (mtDNA) .  

 

That said I also think there is a new population of children like Hannah Poling

who have an acquired mito dysfunction due to exposure to viruses and toxins.

This is why the # of kids with autistic symptoms has exploded. The number could

be 72,000 + according to

Dr. Poling.  It is unlikely that there would be a mass explosion of a genetic

defect so it has to be due to something environmental.  

 

The ASD symptoms in many kids are likely an indication of an underlying mito

problem.  These kids would likely not improve so much with treatment if there

autism was genetic in origin.  Also if their autism were genetic there would

likely be signs present from birth vs a child who developed normally then had a

regression later.  My son would be in the later group.

 

 

>

> If you have this SNP, SOD2 +/+, which affects

> the mitochondria, is this a genetic predisposition

> for getting Autism? Does the environment alter

> the genes, whether that was with an ancestor or a new

> toxin that overloads the system? And if you eliminate

> the toxins, the genes work better with an improved

> environment?

>

>

[Guest guest]

Not " always " . The first case of autism was discovered by Leo Kanner

after mercury was introduced into the medical field.

My first child developed normally then regressed into autism with his

18 month vaccinations, but my second seemed different (autistic?)

from birth. The difference for my kids was that the second child got

the hepatitis b shot at birth. Who knows what that did to his little

body, we had to go to the ER less than a week after he was born for

high fever and constant crying.

Hep B vaccine has been accused of molecular mimicry and they don't

know enough about it to be giving it to anyone, it's a tragedy they

allow it to be given at birth.

So, given the fact that babies are getting vaccinations at birth,

it's impossible to say that their autism is genetic, how would you

know anymore?

I believe that genetic disorders are due to environmental insults

that have altered the body at the cellular level (DNA/mito) and

this " defect " is sometimes passed down the family line.

Interestingly, many of our kids have sensitivities to the food

ingredients contained in the vaccinations. If food particles are in

with the adjuvants of the vaccinations, have they triggered immune

response (autoantibodies) against the foods as well? I am curious.

Have you read this study?

Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from

mothers of children with autism.

Authors:

, Loren A.1

Ashwood, 2,3

Braunschweig, 4

Cabanlit, Maricel4

Van de Water, Judy3,4

Amaral, G.1,3 dgamaral@...

Source:

Brain, Behavior & Immunity; Aug2008, Vol. 22 Issue 6, p806-816, 11p

Abstract: Autism together with Asperger syndrome and pervasive

developmental disorder not otherwise specified form a spectrum of

conditions (autism spectrum disorders or ASD) that is characterized

by disturbances in social behavior, impaired communication and the

presence of stereotyped behaviors or circumscribed interests. Recent

estimates indicate a prevalence of ASD of 1 per 150 (). The cause(s)

of most cases of ASD are unknown but there is an emerging consensus

that ASD have multiple etiologies. One proposed cause of ASD is

exposure of the fetal brain to maternal autoantibodies during

pregnancy [Dalton, P., Deacon, R., Blamire, A., Pike, M., McKinlay,

I., Stein, J., Styles, P., , A., 2003. Maternal neuronal

antibodies associated with autism and a language disorder. Ann.

Neurol. 53, 533–537]. To provide evidence for this hypothesis, four

rhesus monkeys were exposed prenatally to human IgG collected from

mothers of multiple children diagnosed with ASD. Four control rhesus

monkeys were exposed to human IgG collected from mothers of multiple

typically developing children. Five additional monkeys were untreated

controls. Monkeys were observed in a variety of behavioral paradigms

involving unique social situations. Behaviors were scored by trained

observers and overall activity was monitored with actimeters. Rhesus

monkeys gestationally exposed to IgG class antibodies from mothers of

children with ASD consistently demonstrated increased whole-body

stereotypies across multiple testing paradigms. These monkeys were

also hyperactive compared to controls. Treatment with IgG purified

from mothers of typically developing children did not induce

stereotypical or hyperactive behaviors. These findings support the

potential for an autoimmune etiology in a subgroup of patients with

neurodevelopmental disorders. This research raises the prospect of

prenatal evaluation for neurodevelopmental risk factors and the

potential for preventative therapeutics.

> >

> > If you have this SNP, SOD2 +/+, which affects

> > the mitochondria, is this a genetic predisposition

> > for getting Autism? Does the environment alter

> > the genes, whether that was with an ancestor or a new

> > toxin that overloads the system? And if you eliminate

> > the toxins, the genes work better with an improved

> > environment?

> >

> >

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[Guest guest]

> My first child developed normally then regressed into autism with his

> 18 month vaccinations, but my second seemed different (autistic?)

> from birth. The difference for my kids was that the second child got

> the hepatitis b shot at birth. Who knows what that did to his little

> body, we had to go to the ER less than a week after he was born for

> high fever and constant crying.

My #2 has a dx of " classic Kanner's autism " , severe, low functioning.

My other kids all have various presentations of spectrum also. None

of them really " regressed " .

My #2 received his HepB vax at birth. He cried immediately following

the shot, and nonstop for 12 months afterward. It has taken me 9

years to recover him. That vax, at birth, is NASTY.

> I believe that genetic disorders are due to environmental insults

> that have altered the body at the cellular level (DNA/mito) and

> this " defect " is sometimes passed down the family line.

I know of 3 families who reversed a celiac dx with chelation, and

celiac is also supposed to be genetic.

Dana

[Guest guest]

I had to rush my dd to the ER about 10 days after the Hep B vaccine

too. She was really agitated and had a walnut sized lump under her

right ear. Oh I am sooooo mad!!! It messed my dd up!

On Aug 20, 2008, at 11:00 AM, wrote:

> Not " always " . The first case of autism was discovered by Leo Kanner

> after mercury was introduced into the medical field.

>

> My first child developed normally then regressed into autism with his

> 18 month vaccinations, but my second seemed different (autistic?)

> from birth. The difference for my kids was that the second child got

> the hepatitis b shot at birth. Who knows what that did to his little

> body, we had to go to the ER less than a week after he was born for

> high fever and constant crying.

>

> Hep B vaccine has been accused of molecular mimicry and they don't

> know enough about it to be giving it to anyone, it's a tragedy they

> allow it to be given at birth.

>

> So, given the fact that babies are getting vaccinations at birth,

> it's impossible to say that their autism is genetic, how would you

> know anymore?

>

> I believe that genetic disorders are due to environmental insults

> that have altered the body at the cellular level (DNA/mito) and

> this " defect " is sometimes passed down the family line.

>

> Interestingly, many of our kids have sensitivities to the food

> ingredients contained in the vaccinations. If food particles are in

> with the adjuvants of the vaccinations, have they triggered immune

> response (autoantibodies) against the foods as well? I am curious.

>

> Have you read this study?

>

> Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from

> mothers of children with autism.

>

> Authors:

> , Loren A.1

> Ashwood, 2,3

> Braunschweig, 4

> Cabanlit, Maricel4

> Van de Water, Judy3,4

> Amaral, G.1,3 dgamaral@...

> Source:

> Brain, Behavior & Immunity; Aug2008, Vol. 22 Issue 6, p806-816, 11p

>

> Abstract: Autism together with Asperger syndrome and pervasive

> developmental disorder not otherwise specified form a spectrum of

> conditions (autism spectrum disorders or ASD) that is characterized

> by disturbances in social behavior, impaired communication and the

> presence of stereotyped behaviors or circumscribed interests. Recent

> estimates indicate a prevalence of ASD of 1 per 150 (). The cause(s)

> of most cases of ASD are unknown but there is an emerging consensus

> that ASD have multiple etiologies. One proposed cause of ASD is

> exposure of the fetal brain to maternal autoantibodies during

> pregnancy [Dalton, P., Deacon, R., Blamire, A., Pike, M., McKinlay,

> I., Stein, J., Styles, P., , A., 2003. Maternal neuronal

> antibodies associated with autism and a language disorder. Ann.

> Neurol. 53, 533–537]. To provide evidence for this hypothesis, four

> rhesus monkeys were exposed prenatally to human IgG collected from

> mothers of multiple children diagnosed with ASD. Four control rhesus

> monkeys were exposed to human IgG collected from mothers of multiple

> typically developing children. Five additional monkeys were untreated

> controls. Monkeys were observed in a variety of behavioral paradigms

> involving unique social situations. Behaviors were scored by trained

> observers and overall activity was monitored with actimeters. Rhesus

> monkeys gestationally exposed to IgG class antibodies from mothers of

> children with ASD consistently demonstrated increased whole-body

> stereotypies across multiple testing paradigms. These monkeys were

> also hyperactive compared to controls. Treatment with IgG purified

> from mothers of typically developing children did not induce

> stereotypical or hyperactive behaviors. These findings support the

> potential for an autoimmune etiology in a subgroup of patients with

> neurodevelopmental disorders. This research raises the prospect of

> prenatal evaluation for neurodevelopmental risk factors and the

> potential for preventative therapeutics.

>

>

> > >

> > > If you have this SNP, SOD2 +/+, which affects

> > > the mitochondria, is this a genetic predisposition

> > > for getting Autism? Does the environment alter

> > > the genes, whether that was with an ancestor or a new

> > > toxin that overloads the system? And if you eliminate

> > > the toxins, the genes work better with an improved

> > > environment?

> > >

> > >

> >

> >

> >

> >

> >

> >

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> >

[Guest guest]

External factors, such as diet, can alter which genes are expressed.

One example of this is the ketogenic diet and epilepsy. Many of these

kids have intractable epilepsy and are able to come off their seizure

meds. I don't know why these kids have epilepsy. Was it genetic or the

environment. Remember the movie, First Do No Harm? It was based upon

the true story of a family which cured their son by using the ketogenic

diet. The medical establishment wanted to put the child on medications

which resulted in some really bad side effects. The mother rediscovered

the diet in some medical journal articles written in the 1920s and

found a program which allowed him to enroll.

IMHO, most cases of autism are induced by external factors, such as

vaccines, mercury, viruses, etc. How else would you explain the

increasing numbers? I'm very hopeful that diet, chelation, supplements,

etc. will be able to address any *genetic or environmental issues*

we're facing. In case you are interested, here's a link to an article

on gene expression and the ketogenic diet.

http://tinyurl.com/atzyv

>

> If you have this SNP, SOD2 +/+, which affects

> the mitochondria, is this a genetic predisposition

> for getting Autism? Does the environment alter

> the genes, whether that was with an ancestor or a new

> toxin that overloads the system? And if you eliminate

> the toxins, the genes work better with an improved

> environment?

>

[Guest guest]

SAMe methylates DNA among many other things, so if methylation is

impaired (mercury does this very well), then this too can effect gene

expression.

I agree with Andy. The polling mitochondria argument is a red herring.

And from what I gather it is working really well.

orelindel wrote:

>

> External factors, such as diet, can alter which genes are expressed.

> One example of this is the ketogenic diet and epilepsy. Many of these

> kids have intractable epilepsy and are able to come off their seizure

> meds. I don't know why these kids have epilepsy. Was it genetic or the

> environment. Remember the movie, First Do No Harm? It was based upon

> the true story of a family which cured their son by using the ketogenic

> diet. The medical establishment wanted to put the child on medications

> which resulted in some really bad side effects. The mother rediscovered

> the diet in some medical journal articles written in the 1920s and

> found a program which allowed him to enroll.

>

> IMHO, most cases of autism are induced by external factors, such as

> vaccines, mercury, viruses, etc. How else would you explain the

> increasing numbers? I'm very hopeful that diet, chelation, supplements,

> etc. will be able to address any *genetic or environmental issues*

> we're facing. In case you are interested, here's a link to an article

> on gene expression and the ketogenic diet.

>

> http://tinyurl.com/atzyv <http://tinyurl.com/atzyv>

>

>

> >

> > If you have this SNP, SOD2 +/+, which affects

> > the mitochondria, is this a genetic predisposition

> > for getting Autism? Does the environment alter

> > the genes, whether that was with an ancestor or a new

> > toxin that overloads the system? And if you eliminate

> > the toxins, the genes work better with an improved

> > environment?

> >

>

>

[Guest guest]

> >

> > If you have this SNP, SOD2 +/+, which affects

> > the mitochondria, is this a genetic predisposition

> > for getting Autism? Does the environment alter

> > the genes, whether that was with an ancestor or a new

> > toxin that overloads the system? And if you eliminate

> > the toxins, the genes work better with an improved

> > environment?

> >

> >

>

> hi there, I would like to add a comment about parents who think

there children born autistic, because he or she never was o.k from

birth., we have to remember, our first vaccine goes when our little

one is either 2 or 4 months old, and that is DPT, if we take a look

at the side effect of each one of them " if we have a gene that is

suseptable to toxin such as tetanus or pertusis " , we will see a child

who is behaving obnormal, there is a movie name " Vaccine Nation " ,

that Dr. Null made that movie, won lots of prizes, it is showing what

devestating effect that vaccine causes even from the beginning,

including Sudden Infent Death, BSS, Autism and so on, we start the

vaccine so soon, that it wont allow us to see our child in a normal

state, one vaccine after another, till we knock them out and we take

the life out of them, NOT FOR a moment let them to tell, that our

child was born autistic, some boxeres get nocked out in the first

round and some in the round 12, that is the same in our kids, some of

our kids were out in the first vaccine and some of 'em in the last,

so treating the vaccine will bring our kids back I hope.

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[Guest guest]

If methylation is impaired then SAMe doesn't methylate a whole lot of

things including DNA. This will effect gene expression and can be

another way you end up with a mitochondrial disorder.

I think Andy is right. The mitochondrial issue is a red herring to

distract people from the real issues.

And it is working.

arvinseroj wrote:

>

>

> > >

> > > If you have this SNP, SOD2 +/+, which affects

> > > the mitochondria, is this a genetic predisposition

> > > for getting Autism? Does the environment alter

> > > the genes, whether that was with an ancestor or a new

> > > toxin that overloads the system? And if you eliminate

> > > the toxins, the genes work better with an improved

> > > environment?

> > >

> > >

> >

> > hi there, I would like to add a comment about parents who think

> there children born autistic, because he or she never was o.k from

> birth., we have to remember, our first vaccine goes when our little

> one is either 2 or 4 months old, and that is DPT, if we take a look

> at the side effect of each one of them " if we have a gene that is

> suseptable to toxin such as tetanus or pertusis " , we will see a child

> who is behaving obnormal, there is a movie name " Vaccine Nation " ,

> that Dr. Null made that movie, won lots of prizes, it is showing what

> devestating effect that vaccine causes even from the beginning,

> including Sudden Infent Death, BSS, Autism and so on, we start the

> vaccine so soon, that it wont allow us to see our child in a normal

> state, one vaccine after another, till we knock them out and we take

> the life out of them, NOT FOR a moment let them to tell, that our

> child was born autistic, some boxeres get nocked out in the first

> round and some in the round 12, that is the same in our kids, some of

> our kids were out in the first vaccine and some of 'em in the last,

> so treating the vaccine will bring our kids back I hope.

> >

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