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This is very interesting! Just one more reason to take fish oil.

Thanks Michele!

> " The finding that in the depressive rats the omega-3 fatty acid

> levels were not decreased, but arachidonic acid was substantially

> increased as compared to controls, is somewhat unexpected, " the

> researchers reported. " But the finding lends itself nicely to the

> theory that increased omega-3 fatty acid intake may shift the

> balance between the two fatty acid families in the brain. It has

> been demonstrated in animal studies that increased omega-3 fatty

> acid intake may result in decreased brain arachidonic acid. "

>

> I'm just beside myself with excitement and posting stuff about AA

to

> various lists. :-) Please excuse me if it isn't of interest to you.

>

> Thanks!

>

>

>

> Michele

> http://www.healthgazelle.org

> http://www.kidslikemine.org

>

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> I guess a few weeks ago, Andy mentioned that peanuts and peanut oil

> are high in arachidonic acid (AA). So I asked around on some cystic

> fibrosis (CF) lists and it turns out that, yes, people with CF are

> typically high in AA. I asked around because I gave up peanuts and

> peanut oil about 3 years ago and I have done much better since

> then. I assumed it was some weird allergy -- " weird " because it

> didn't make me itch or have hives and so forth. Andy's remark was

> an Aha! moment for me because it potentially explains why I am doing

> better without peanuts and peanut oil even though I have no signs of

> an allergic reaction to them. AA is inflammatory and inflammation

> is a major issue for people with CF.

This may be one of the pieces of info that I have been searching for,

for my #4, who still has severe mito issues despite years of mito

cocktail and fish oil [and despite being the most NT of my kids before

I started biomedical, she was ADHD]. She DOES complain of

body-itchiness at times, and an upset stomach. One of those times was

yesterday, and she did eat a peanut butter sandwich yesterday.

> Anyway, I know most folks on this list don't have CF so my reasons

> for surfing the web for info on AA aren't directly related to the

> interests of this group.

Don't assume this. My #4 does not have CF. She DOES have

mitochondrial dysfunction, just like my other three kids, but hers has

been the most difficult to correct.

Dana

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>

> This may be one of the pieces of info that I have been searching

for,

> for my #4,

:-) Glad it's of interest.

who still has severe mito issues despite years of mito

> cocktail and fish oil [and despite being the most NT of my kids

before

> I started biomedical, she was ADHD]. She DOES complain of

> body-itchiness at times, and an upset stomach. One of those times

was

> yesterday, and she did eat a peanut butter sandwich yesterday.

I hope you can get her better.

>

>

> > Anyway, I know most folks on this list don't have CF so my

reasons

> > for surfing the web for info on AA aren't directly related to

the

> > interests of this group.

>

>

> Don't assume this. My #4 does not have CF. She DOES have

> mitochondrial dysfunction, just like my other three kids, but hers

has

> been the most difficult to correct.

>

> Dana

>

Well, it isn't directly related. It's not a CF list. Though,

really, my inquisitive interest in snippets of info like this is

generally received better here than it typically is on CF lists.

Even though a lot of people with CF take supplements, eat carefully,

etc., the general assumption is still that if one has CF, one has to

be on medication permanently (what I refer to as " life long drug

addict, with the help of the conventional drug lords " ).

Anyway, I hope it helps you help your daughter. I'm glad I did my

excited rambling and didn't just post the article. Thanks for

letting me know. :-)

Michele

http://www.healthgazelle.org

http://www.kidslikemine.org

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>

> This is very interesting! Just one more reason to take fish oil.

> Thanks Michele!

You are welcome!

I react allergically to fish oil if I take more than a little, so I

haven't taken it in recent years. But I am so working on better

understanding oils and how they impact my health. :-)

Michele

http://www.healthgazelle.org

http://www.kidslikemine.org

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> PS --

> Dana, I have an email (or three) I sent myself last night with several

> links and little snippets of things I tripped across in my search for

> info on arachidonic acid. I can post that if you are interested.

Sure. I am also researching the Omega 3,6,9 content of foods, if you

have any info on that.

Dana

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>

> Sure. I am also researching the Omega 3,6,9 content of foods, if you

> have any info on that.

>

> Dana

>

No, unfortunately, I don't have that info.

-----------

http://www.revolutionhealth.com/forums/asthma-allergies/asthma/134871

aspirin, asthma, arachidonic acid

" Approximately 10 percent of asthmatics have a very bad reaction to

aspirin. It can cause severe, and occasionally fatal, asthma

attacks. This is because their airways are very sensitive to a

chemical found in aspirin. "

" Prostaglandins, hormone like substances, are formed from the

oxygenation of arachidonic acid, a polyunsaturated fatty acid.

Prostaglandins are not stored in tissue in anticipation of need. They

are synthesized within seconds, act in low concentration, and are

rapidly destroyed. Prostaglandin E (PGE) is a vasodilator, while the

F (PGF) form is vasoconstrictive. Aspirin acts by inhibiting the

conversion of arachidonic acid to PGE & PGF. "

http://www.revolutionhealth.com/search/results?q=arachidonic%

20acid & src=more_related_searches

This is the source of the link above this one and the link below this

one.

http://www.revolutionhealth.com/healthy-living/mens-

health/mind/depression/fishing-good-mood

This is the article already posted to this list.

-----------------------

http://jasn.asnjournals.org/cgi/content/abstract/7/7/1024

Corn oil " is a rich source of linoleic acid (LA; 18:2n-6), a GLA and

arachidonic acid (AA; 20:4n-6) precursor. "

**This might explain why I am not that fond of corn oil, even though I

eat a lot of corn.

-----

http://aem.asm.org/cgi/reprint/57/4/1255.pdf

Arachidonic Acid Production by Fungi

------------------------

http://www.encyclopedia.com/doc/1O39-arachidonicacid.html

arachidonic acid

A Dictionary of Food and Nutrition | Date: 2005

arachidonic acid A long chain polyunsaturated fatty acid (20 : 4 Ăą6).

Not strictly an essential fatty acid, since it can be formed from

linoleic acid, but three times more potent than linoleic acid in

curing the signs of essential fatty acid deficiency. Found in animal

tissues, especially fish, eggs, liver, and brain.

http://www.websters-online-dictionary.org/Ar/Arachidonic_Acid.html

------------

http://www.lef.org/magazine/mag2003/dec2003_report_omega_01.htm

Besides " crowding out " excess arachidonic acid, the omega-3s aid the

body in other ways, too. They have been shown to act on intracellular

signaling pathways, to influence transcription factor activity, and to

modulate gene expression. All of these effects may combine to

alleviate inflammation and disease. As one researcher noted: " Many of

the placebo-controlled trials of fish oil in chronic inflammatory

diseases reveal significant benefit, including decreased disease

activity and lowered use of anti-inflammatory drugs. " 32 Another

scientist reviewed nearly two decades of published research on the use

of fish oil in the treatment of rheumatoid arthritis and

concluded: " Treatment with fish oil has been associated with

improvement…in rheumatoid arthritis. " 34

-------------------

http://www.powerbutter.com/peanut_pb_compare.html

But is regular natural peanut butter really all it's cracked up to be?

I'm afraid the answer to that question is " not really " . When you strip

away all the rhetoric and assumptions surrounding natural peanut

butter, and boil it down to its true nutritional essence, you'll find

that it's really just a dense source of decent calories. That's it. I

say this for two reasons.

First, the " good " fats contained in peanuts are really not so

much " good " as they are " not bad. " They are mainly composed of

monounsaturated fats. And being such they don't pose any health risks

like saturated (or " bad " ) fats do. But because monounsaturated fats

are not considered " essential fatty acids " (in other words you don't

have to consume them in your diet, because your body can make them

from other fats) they also don't really provide any specific health or

athletic benefits. There is no research connecting the intake of

monounsaturated fats with enhancement of any muscular performance or

growth parameter. They simply supply calories.

Second, the level and type of protein found in regular natural peanut

butter is very modest. Containing only 14% of calories as protein, a 2-

ounce serving provides about 14 grams of protein. However, due to an

incomplete amino acid profile, your body is only able to use about

half of that protein to build muscle. So you really only net about 7

grams of usable protein from a hefty 2-ounce serving - which also

contains about 380 calories, with 75% of those calories (25 grams) as

fat. Not a great ratio.

http://www.fatsforhealth.com/introduction/faqs.php

Eicosanoids derived from Arachidonic Acid (AA)

The body processes AA into potentially harmful eicosanoids, the

strongest of which is prostaglandin E2 (PGE2). PGE2 strongly increases

inflammation, constricts blood vessels, and encourages blood clotting.

These properties come into play when the body suffers a wound or

injury - without these eicosanoids, you would bleed to death from the

slightest of cuts. However, in excess, these eicosanoids may be

harmful. Many diseases are directly linked to excessive inflammation

and blood clotting - for example, rheumatoid arthritis and some forms

of stroke and heart attack. High levels of eicosanoids derived from AA

in the body have also been linked to other diseases including diabetic

nerve damage, high blood pressure, allergies, skin inflammations and

cancer.

Arachidonic Acid in the diet also affects our need for GLA

supplementation…

At the same time, the average North American is affected by excessive

intake of Arachidonic Acid which, in high concentrations, causes ill

effects such as inflammation, blood clotting, and blood vessel

constriction.

The GLA solution…

GLA does not require the potentially impaired D6D enzyme for breakdown

by the body. The production of good eicosanoids from GLA will also

counteract the ill effects of excess Arachidonic Acid. The average

North American should therefore supplement the diet with a good source

of GLA such as borage oil or evening primrose oil

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Omega 3,6,and 9 are in chia seed. It comes in little seeds you can

put in food/drinks or in oil capsules. I prefer because vegetarian

and no fish oil risk. Very powerful food...can send you a sheet on it

separately if you like.

:)

Liz

>

> >

> > Sure. I am also researching the Omega 3,6,9 content of foods, if you

> > have any info on that.

> >

> > Dana

> >

>

> No, unfortunately, I don't have that info.

> -----------

> http://www.revolutionhealth.com/forums/asthma-allergies/asthma/134871

> aspirin, asthma, arachidonic acid

>

> " Approximately 10 percent of asthmatics have a very bad reaction to

> aspirin. It can cause severe, and occasionally fatal, asthma

> attacks. This is because their airways are very sensitive to a

> chemical found in aspirin. "

>

> " Prostaglandins, hormone like substances, are formed from the

> oxygenation of arachidonic acid, a polyunsaturated fatty acid.

> Prostaglandins are not stored in tissue in anticipation of need. They

> are synthesized within seconds, act in low concentration, and are

> rapidly destroyed. Prostaglandin E (PGE) is a vasodilator, while the

> F (PGF) form is vasoconstrictive. Aspirin acts by inhibiting the

> conversion of arachidonic acid to PGE & PGF. "

>

>

> http://www.revolutionhealth.com/search/results?q=arachidonic%

> 20acid & src=more_related_searches

> This is the source of the link above this one and the link below this

> one.

>

> http://www.revolutionhealth.com/healthy-living/mens-

> health/mind/depression/fishing-good-mood

> This is the article already posted to this list.

>

>

>

> -----------------------

> http://jasn.asnjournals.org/cgi/content/abstract/7/7/1024

> Corn oil " is a rich source of linoleic acid (LA; 18:2n-6), a GLA and

> arachidonic acid (AA; 20:4n-6) precursor. "

>

> **This might explain why I am not that fond of corn oil, even though I

> eat a lot of corn.

>

> -----

>

> http://aem.asm.org/cgi/reprint/57/4/1255.pdf

>

> Arachidonic Acid Production by Fungi

>

> ------------------------

>

> http://www.encyclopedia.com/doc/1O39-arachidonicacid.html

> arachidonic acid

>

> A Dictionary of Food and Nutrition | Date: 2005

> arachidonic acid A long chain polyunsaturated fatty acid (20 : 4 Ăą6).

> Not strictly an essential fatty acid, since it can be formed from

> linoleic acid, but three times more potent than linoleic acid in

> curing the signs of essential fatty acid deficiency. Found in animal

> tissues, especially fish, eggs, liver, and brain.

>

>

> http://www.websters-online-dictionary.org/Ar/Arachidonic_Acid.html

> ------------

>

> http://www.lef.org/magazine/mag2003/dec2003_report_omega_01.htm

>

> Besides " crowding out " excess arachidonic acid, the omega-3s aid the

> body in other ways, too. They have been shown to act on intracellular

> signaling pathways, to influence transcription factor activity, and to

> modulate gene expression. All of these effects may combine to

> alleviate inflammation and disease. As one researcher noted: " Many of

> the placebo-controlled trials of fish oil in chronic inflammatory

> diseases reveal significant benefit, including decreased disease

> activity and lowered use of anti-inflammatory drugs. " 32 Another

> scientist reviewed nearly two decades of published research on the use

> of fish oil in the treatment of rheumatoid arthritis and

> concluded: " Treatment with fish oil has been associated with

> improvement…in rheumatoid arthritis. " 34

>

> -------------------

> http://www.powerbutter.com/peanut_pb_compare.html

>

> But is regular natural peanut butter really all it's cracked up to be?

>

> I'm afraid the answer to that question is " not really " . When you strip

> away all the rhetoric and assumptions surrounding natural peanut

> butter, and boil it down to its true nutritional essence, you'll find

> that it's really just a dense source of decent calories. That's it. I

> say this for two reasons.

> First, the " good " fats contained in peanuts are really not so

> much " good " as they are " not bad. " They are mainly composed of

> monounsaturated fats. And being such they don't pose any health risks

> like saturated (or " bad " ) fats do. But because monounsaturated fats

> are not considered " essential fatty acids " (in other words you don't

> have to consume them in your diet, because your body can make them

> from other fats) they also don't really provide any specific health or

> athletic benefits. There is no research connecting the intake of

> monounsaturated fats with enhancement of any muscular performance or

> growth parameter. They simply supply calories.

>

>

> Second, the level and type of protein found in regular natural peanut

> butter is very modest. Containing only 14% of calories as protein, a 2-

> ounce serving provides about 14 grams of protein. However, due to an

> incomplete amino acid profile, your body is only able to use about

> half of that protein to build muscle. So you really only net about 7

> grams of usable protein from a hefty 2-ounce serving - which also

> contains about 380 calories, with 75% of those calories (25 grams) as

> fat. Not a great ratio.

>

>

>

> http://www.fatsforhealth.com/introduction/faqs.php

>

> Eicosanoids derived from Arachidonic Acid (AA)

> The body processes AA into potentially harmful eicosanoids, the

> strongest of which is prostaglandin E2 (PGE2). PGE2 strongly increases

> inflammation, constricts blood vessels, and encourages blood clotting.

> These properties come into play when the body suffers a wound or

> injury - without these eicosanoids, you would bleed to death from the

> slightest of cuts. However, in excess, these eicosanoids may be

> harmful. Many diseases are directly linked to excessive inflammation

> and blood clotting - for example, rheumatoid arthritis and some forms

> of stroke and heart attack. High levels of eicosanoids derived from AA

> in the body have also been linked to other diseases including diabetic

> nerve damage, high blood pressure, allergies, skin inflammations and

> cancer.

>

> Arachidonic Acid in the diet also affects our need for GLA

> supplementation…

> At the same time, the average North American is affected by excessive

> intake of Arachidonic Acid which, in high concentrations, causes ill

> effects such as inflammation, blood clotting, and blood vessel

> constriction.

>

> The GLA solution…

> GLA does not require the potentially impaired D6D enzyme for breakdown

> by the body. The production of good eicosanoids from GLA will also

> counteract the ill effects of excess Arachidonic Acid. The average

> North American should therefore supplement the diet with a good source

> of GLA such as borage oil or evening primrose oil

>

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> Omega 3,6,and 9 are in chia seed. It comes in little seeds you can

> put in food/drinks or in oil capsules. I prefer because vegetarian

> and no fish oil risk. Very powerful food...can send you a sheet on it

> separately if you like.

I am researching the Omega 3,6,9 content of all/most foods. But

thanks for the idea.

Dana

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