Guest guest Posted July 30, 2006 Report Share Posted July 30, 2006 HCG is an alternative option to coming off all meds if your testicles work and you are definitely secondary, but it will not help your HPTA recover. In fact quite the reverse HCG will surpress your HPTA because it replaces LH with an analogue and when you come off it LH will be rock bottom. Clomid or Arimidex in small doses could boost your HPTA by lowering esradiol. But that would only be appropriate if your estradiol isn't low to start with. In fact your test results are missing estradiol. It would be helpful for you to get it tested. If it is high it could be accouting for your sluggish pituitary and signal a requirement for the use of an anti estrogen or arimidex in order to get the HPTA fired up and free testosterone increased. > > Hello, > > I am 22 years old with secondary hypogonadism, induced a couple of > years ago after having lost a lot of weight with an athletics- > related eating disorder. After recovering from the disorder and > regaining some weight, I still felt poor and went to see an > endocrinologist. My T, LH and FSH levels were all low, indicating > secondary hypogonadism. I was put on Androgel 5g for a few months, > managed to gain a few more pounds in the gym, but my T levels were > still low. I increased to 10g, added further mass, and got my T > levels within range. > > I was confident after a pituitary scan turned up negative that my > HPTA could kick back in, and I tapered off of TRT last fall. After > feeling like junk, I desperately went back to the doc and requested > a protocol of hCG/Clomid/Nolva to kick-start my HPTA, but the > confused endo was under the impression that I wasn't a solveable > case and decided to put me on injections. In January of this year, > he called me up with results from bloodwork that I had done after my > earlier time off of TRT and told me that I was right, my HPTA would > eventually kick in, and asked me to taper off of injections. > > Right now, I have been TRT free since February, but my latest blood > work isn't very impressive: > > STSH: 2.23 (0.35-5.00 mU/L) > LH: 3.0 (1-9 IU/L) > FSH: 3.0 (1-14 IU/L) > TESTOSTERONE: 11.1 (8.0-38.0 nmol/L) > PROLACTIN: 7.0 (< 18 ug/L) > FREE TESTOSTERONE: 15.9 (40.0-85.0 pmol/L) > > Clearly my HPTA is still in remission. Although there are days where > my sexual function works (with much coaxing) and my workouts are > good and although I am a generally chipper guy, I still feel tired > most of the time and my libido is waning. I know it takes a while > for the HPTA to kick back in (especially considering it was shut > down for two years), but am I wrong to believe that I should do a > protocol of hCG/Clomid/Nolva to kick-start my system? > > I live in Canada and I have been looking for a good doctor who will > help me with this protocol. However, I may have to wait months to > see another specialist, and he/she will probably shrug off my > suggestion and try to put me back on TRT, which I do not need! > > What do you suggest I do? Should I wait it out a bit longer? If so, > is there anything that will help 'speed along' the HPTA's restarting > process? I could obtain hCG, Clomid and Nolva on my own and do my > own protocol, but I would rather be supervised during my treatment. > > Thanks! > > - Ken > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2006 Report Share Posted July 30, 2006 Thanks. I'd really like for my case to be easily solved with an AI. I'm currently taking an OTC AI, Novedex XT by Gaspari, which is essentially a less effective version of Nolvedex. I don't have blood work slated until early September; should I get some Arimidex and try a small cycle to see if I feel any better? - Ken > > > > Hello, > > > > I am 22 years old with secondary hypogonadism, induced a couple of > > years ago after having lost a lot of weight with an athletics- > > related eating disorder. After recovering from the disorder and > > regaining some weight, I still felt poor and went to see an > > endocrinologist. My T, LH and FSH levels were all low, indicating > > secondary hypogonadism. I was put on Androgel 5g for a few months, > > managed to gain a few more pounds in the gym, but my T levels were > > still low. I increased to 10g, added further mass, and got my T > > levels within range. > > > > I was confident after a pituitary scan turned up negative that my > > HPTA could kick back in, and I tapered off of TRT last fall. After > > feeling like junk, I desperately went back to the doc and > requested > > a protocol of hCG/Clomid/Nolva to kick-start my HPTA, but the > > confused endo was under the impression that I wasn't a solveable > > case and decided to put me on injections. In January of this year, > > he called me up with results from bloodwork that I had done after > my > > earlier time off of TRT and told me that I was right, my HPTA > would > > eventually kick in, and asked me to taper off of injections. > > > > Right now, I have been TRT free since February, but my latest > blood > > work isn't very impressive: > > > > STSH: 2.23 (0.35-5.00 mU/L) > > LH: 3.0 (1-9 IU/L) > > FSH: 3.0 (1-14 IU/L) > > TESTOSTERONE: 11.1 (8.0-38.0 nmol/L) > > PROLACTIN: 7.0 (< 18 ug/L) > > FREE TESTOSTERONE: 15.9 (40.0-85.0 pmol/L) > > > > Clearly my HPTA is still in remission. Although there are days > where > > my sexual function works (with much coaxing) and my workouts are > > good and although I am a generally chipper guy, I still feel tired > > most of the time and my libido is waning. I know it takes a while > > for the HPTA to kick back in (especially considering it was shut > > down for two years), but am I wrong to believe that I should do a > > protocol of hCG/Clomid/Nolva to kick-start my system? > > > > I live in Canada and I have been looking for a good doctor who > will > > help me with this protocol. However, I may have to wait months to > > see another specialist, and he/she will probably shrug off my > > suggestion and try to put me back on TRT, which I do not need! > > > > What do you suggest I do? Should I wait it out a bit longer? If > so, > > is there anything that will help 'speed along' the HPTA's > restarting > > process? I could obtain hCG, Clomid and Nolva on my own and do my > > own protocol, but I would rather be supervised during my treatment. > > > > Thanks! > > > > - Ken > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2006 Report Share Posted July 30, 2006 Hi Ken: You sure to get lots of answers. Take them all (Including mine) with a grain of salt. I think the best bet is to try to find a Doctor with more experience in this. If your 'secondary " then Androgel was the (My amateur two cents) wrong drug to prescribe. Another option which has worked for me in the past is to either mail or bring some material for the Doctor to bone up on. I was caught in the situation where my Testosterone readings were slightly above the lab lower range but they were using the numbers from 1998 standards. I brought the AACE guidelines from 2002 and the Age vrs Testosterone chart from here and my Doctor actualy sat down and read them. I also brought a copy of a book called " The Testosterone Syndrome " as a gift. I asked her to tell me if it was good material for me to use or not. She said " It was " btw. ;-) While your stuck with low numbers your very apt to feel all those lousy symptoms. Hang in there and lets hope that treatment can get your natural system firing correctly. If not you can always go back to testosterone but don't jump into that without trying everything else first. There are drawbacks to HRT (probably testicular atrophy, possible gynocomastia) > > Hello, > > I am 22 years old with secondary hypogonadism, induced a couple of > years ago after having lost a lot of weight with an athletics- > related eating disorder. After recovering from the disorder and > regaining some weight, I still felt poor and went to see an > endocrinologist. My T, LH and FSH levels were all low, indicating > secondary hypogonadism. I was put on Androgel 5g for a few months, > managed to gain a few more pounds in the gym, but my T levels were > still low. I increased to 10g, added further mass, and got my T > levels within range. > > I was confident after a pituitary scan turned up negative that my > HPTA could kick back in, and I tapered off of TRT last fall. After > feeling like junk, I desperately went back to the doc and requested > a protocol of hCG/Clomid/Nolva to kick-start my HPTA, but the > confused endo was under the impression that I wasn't a solveable > case and decided to put me on injections. In January of this year, > he called me up with results from bloodwork that I had done after my > earlier time off of TRT and told me that I was right, my HPTA would > eventually kick in, and asked me to taper off of injections. > > Right now, I have been TRT free since February, but my latest blood > work isn't very impressive: > > STSH: 2.23 (0.35-5.00 mU/L) > LH: 3.0 (1-9 IU/L) > FSH: 3.0 (1-14 IU/L) > TESTOSTERONE: 11.1 (8.0-38.0 nmol/L) > PROLACTIN: 7.0 (< 18 ug/L) > FREE TESTOSTERONE: 15.9 (40.0-85.0 pmol/L) > > Clearly my HPTA is still in remission. Although there are days where > my sexual function works (with much coaxing) and my workouts are > good and although I am a generally chipper guy, I still feel tired > most of the time and my libido is waning. I know it takes a while > for the HPTA to kick back in (especially considering it was shut > down for two years), but am I wrong to believe that I should do a > protocol of hCG/Clomid/Nolva to kick-start my system? > > I live in Canada and I have been looking for a good doctor who will > help me with this protocol. However, I may have to wait months to > see another specialist, and he/she will probably shrug off my > suggestion and try to put me back on TRT, which I do not need! > > What do you suggest I do? Should I wait it out a bit longer? If so, > is there anything that will help 'speed along' the HPTA's restarting > process? I could obtain hCG, Clomid and Nolva on my own and do my > own protocol, but I would rather be supervised during my treatment. > > Thanks! > > - Ken > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2006 Report Share Posted July 30, 2006 Hey Ken - welcome to the group. This is not my area of expertise so I rely on what I have read. Body builders typically have to restart their HPTA following cycles of steroid use so it makes since to me if you have not damaged one of your organs that you too should be able to restart especially at your age. Listed below is a post from intense training. It describes how they use clomid to restart and why. You may want to investigate this further before pursuing it. Good Luck and keep us posted - Arkansas This is from slat1. Lots of good info, seems to cover everything. Why Bodybuilders Use Clomid Clomid is a generic name for Clomiphene Citrate and is a synthetic oestrogen. It is prescribed medically to aid ovulation in low fertility females. Another generic name is Serophene. Most anabolic steroids, especially the androgens, cause inhibition of the body's own testosterone production. When a bodybuilder comes off a steroid cycle, natural testosterone production is zero and the levels of the steroids taken in the blood are diminishing. This leaves the ratios of catabolic : anabolic hormones in the blood high, hence the body is in a state of catabolism, and, as a result, much of the muscle tissue that was gained on the cycle is now going to be lost. Clomid stimulates the hypothalamus to, in turn stimulant the anterior pituitary gland (aka hypophysis) to release gonadotrophic hormones. The gonadotrophic hormones are follicle stimulating hormone (FSH) and luteinizing hormone (LH - aka interstitial cell stimulating hormone (ICSH)). FSH stimulates the testes to produce more testosterone, and LH stimulates them to secrete more testosterone. This feedback mechanism is known as the hypothalamic-pituitary-testes axis (HPTA), and results in an increase of the body's own testosterone production and blood levels rise, to, in part, compensate for the diminishing levels of exogenous steroids. This is vital to minimise post cycle muscle losses. Not all steroids do cause shut down of the feedback mechanism. Everyone is different and you must also take into account how long you have been using a certain steroid and at what dose in order to determine if you need Clomid or not. Clomid also works as an anti-oestrogen. As it's a weak synthetic oestrogen, it binds to oestrogen receptors on cells blocking them to oestrogen in the blood. This minimises the negative effects like gynecomastia and water retention that may be a result of oestrogen that has aromatised from testosterone. It's effect as an anti-oestrogen are quite weak though, and it should not be relied upon if you are going to be using androgenic steroids that aromatise at a rapid rate, or if you are pre-disposed to gynecomastia. Arimidex and Nolvadex (Tamoxifen) are far more effective anti-oestrogens. Important note: Clomid does not, as is often thought, stimulate the release of natural testosterone, but rather works at reducing the oestrogenic inhibition caused by the steroid cycle. It does this in a similar manner to the way it and Nolvadex block oestrogen receptors in nipples to combat gyno development, i.e. by blocking the oestrogen receptors in the hypothalamus and pituitary thus reducing the inhibition from the elevated oestrogen. This allows LH levels to return to normal, or even above normal levels, and in turn, natural testosterone levels to also normalise. Inhibition of the HPTA is caused by either elevated androgen, oestrogen or progesterone levels. On cessation of the steroid cycle, androgen levels begin to fall and Clomid dosing is normally commenced according to the half-life of the longest acting drug in the system (see below). This may also explain the reason individuals often find post-deca recovery more difficult, as the progesterone presence is untouched by the Clomid. We know that Clomid and Nolvadex (being very similar chemically) are both ineffective with regard to reducing progesterone related gyno, so it is reasonable to assume that Clomid has little effect against progesterone levels. ken_gildner <kengildner@...> wrote: Hello, I am 22 years old with secondary hypogonadism, induced a couple of years ago after having lost a lot of weight with an athletics- related eating disorder. After recovering from the disorder and regaining some weight, I still felt poor and went to see an endocrinologist. My T, LH and FSH levels were all low, indicating secondary hypogonadism. I was put on Androgel 5g for a few months, managed to gain a few more pounds in the gym, but my T levels were still low. I increased to 10g, added further mass, and got my T levels within range. I was confident after a pituitary scan turned up negative that my HPTA could kick back in, and I tapered off of TRT last fall. After feeling like junk, I desperately went back to the doc and requested a protocol of hCG/Clomid/Nolva to kick-start my HPTA, but the confused endo was under the impression that I wasn't a solveable case and decided to put me on injections. In January of this year, he called me up with results from bloodwork that I had done after my earlier time off of TRT and told me that I was right, my HPTA would eventually kick in, and asked me to taper off of injections. Right now, I have been TRT free since February, but my latest blood work isn't very impressive: STSH: 2.23 (0.35-5.00 mU/L) LH: 3.0 (1-9 IU/L) FSH: 3.0 (1-14 IU/L) TESTOSTERONE: 11.1 (8.0-38.0 nmol/L) PROLACTIN: 7.0 (< 18 ug/L) FREE TESTOSTERONE: 15.9 (40.0-85.0 pmol/L) Clearly my HPTA is still in remission. Although there are days where my sexual function works (with much coaxing) and my workouts are good and although I am a generally chipper guy, I still feel tired most of the time and my libido is waning. I know it takes a while for the HPTA to kick back in (especially considering it was shut down for two years), but am I wrong to believe that I should do a protocol of hCG/Clomid/Nolva to kick-start my system? I live in Canada and I have been looking for a good doctor who will help me with this protocol. However, I may have to wait months to see another specialist, and he/she will probably shrug off my suggestion and try to put me back on TRT, which I do not need! What do you suggest I do? Should I wait it out a bit longer? If so, is there anything that will help 'speed along' the HPTA's restarting process? I could obtain hCG, Clomid and Nolva on my own and do my own protocol, but I would rather be supervised during my treatment. Thanks! - Ken --------------------------------- How low will we go? Check out Messenger’s low PC-to-Phone call rates. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2006 Report Share Posted July 30, 2006 Thanks for the reading material, it's making me consider doing a standalone Clomid cycle to try to boost my HPTA. Just curious, however, I have heard that Clomid has a number of negative side effects. Does it not cause emotions to flare up and problems with eyesight? Thanks, - Ken > > Hey Ken - welcome to the group. This is not my area of expertise so I rely on what I have read. Body builders typically have to restart their HPTA following cycles of steroid use so it makes since to me if you have not damaged one of your organs that you too should be able to restart especially at your age. Listed below is a post from intense training. It describes how they use clomid to restart and why. You may want to investigate this further before pursuing it. Good Luck and keep us posted - > > Arkansas > > This is from slat1. Lots of good info, seems to cover everything. > > Why Bodybuilders Use Clomid > Clomid is a generic name for Clomiphene Citrate and is a synthetic oestrogen. It is prescribed medically to aid ovulation in low fertility females. Another generic name is Serophene. > > Most anabolic steroids, especially the androgens, cause inhibition of the body's own testosterone production. When a bodybuilder comes off a steroid cycle, natural testosterone production is zero and the levels of the steroids taken in the blood are diminishing. This leaves the ratios of catabolic : anabolic hormones in the blood high, hence the body is in a state of catabolism, and, as a result, much of the muscle tissue that was gained on the cycle is now going to be lost. > > Clomid stimulates the hypothalamus to, in turn stimulant the anterior pituitary gland (aka hypophysis) to release gonadotrophic hormones. The gonadotrophic hormones are follicle stimulating hormone (FSH) and luteinizing hormone (LH - aka interstitial cell stimulating hormone (ICSH)). FSH stimulates the testes to produce more testosterone, and LH stimulates them to secrete more testosterone. This feedback mechanism is known as the hypothalamic- pituitary-testes axis (HPTA), and results in an increase of the body's own testosterone production and blood levels rise, to, in part, compensate for the diminishing levels of exogenous steroids. This is vital to minimise post cycle muscle losses. > > Not all steroids do cause shut down of the feedback mechanism. Everyone is different and you must also take into account how long you have been using a certain steroid and at what dose in order to determine if you need Clomid or not. > > Clomid also works as an anti-oestrogen. As it's a weak synthetic oestrogen, it binds to oestrogen receptors on cells blocking them to oestrogen in the blood. This minimises the negative effects like gynecomastia and water retention that may be a result of oestrogen that has aromatised from testosterone. > > It's effect as an anti-oestrogen are quite weak though, and it should not be relied upon if you are going to be using androgenic steroids that aromatise at a rapid rate, or if you are pre-disposed to gynecomastia. Arimidex and Nolvadex (Tamoxifen) are far more effective anti-oestrogens. > > Important note: Clomid does not, as is often thought, stimulate the release of natural testosterone, but rather works at reducing the oestrogenic inhibition caused by the steroid cycle. It does this in a similar manner to the way it and Nolvadex block oestrogen receptors in nipples to combat gyno development, i.e. by blocking the oestrogen receptors in the hypothalamus and pituitary thus reducing the inhibition from the elevated oestrogen. This allows LH levels to return to normal, or even above normal levels, and in turn, natural testosterone levels to also normalise. > > Inhibition of the HPTA is caused by either elevated androgen, oestrogen or progesterone levels. On cessation of the steroid cycle, androgen levels begin to fall and Clomid dosing is normally commenced according to the half-life of the longest acting drug in the system (see below). > > This may also explain the reason individuals often find post-deca recovery more difficult, as the progesterone presence is untouched by the Clomid. We know that Clomid and Nolvadex (being very similar chemically) are both ineffective with regard to reducing progesterone related gyno, so it is reasonable to assume that Clomid has little effect against progesterone levels. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 30, 2006 Report Share Posted July 30, 2006 Thank you, . I will bring in some reading info for the next specialist that I see and I'll be sure to hang tough. It makes sense that my HPTA doesn't want to kick back in so quickly as it has been shut down for over two years. - Ken > > Hi Ken: > > You sure to get lots of answers. Take them all (Including mine) with > a grain of salt. I think the best bet is to try to find a Doctor with > more experience in this. If your 'secondary " then Androgel was the > (My amateur two cents) wrong drug to prescribe. > > Another option which has worked for me in the past is to either mail > or bring some material for the Doctor to bone up on. I was caught in > the situation where my Testosterone readings were slightly above the > lab lower range but they were using the numbers from 1998 standards. > I brought the AACE guidelines from 2002 and the Age vrs Testosterone > chart from here and my Doctor actualy sat down and read them. I also > brought a copy of a book called " The Testosterone Syndrome " as a gift. > I asked her to tell me if it was good material for me to use or not. > She said " It was " btw. ;-) > > While your stuck with low numbers your very apt to feel all those > lousy symptoms. Hang in there and lets hope that treatment can get > your natural system firing correctly. If not you can always go back > to testosterone but don't jump into that without trying everything > else first. There are drawbacks to HRT (probably testicular atrophy, > possible gynocomastia) > Quote Link to comment Share on other sites More sharing options...
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