Methyl Jasmonate kills cancer

[Guest guest]

The Anti-Cancer Fragrance Methyl Jasmonate Can Be Effectively

Introduced Into the Blood with a Simple Steam Inhaler

This essay is reprinted from our subscription blog in the public interest.

One of the members sent me this idea. Go to Amazon and purchase a

Vicks Personal Steam Inhaler. It only cost about $25. You put the

methyl jasmonate in the distilled water and inhale the vapors from the

mask. It is adjustable so you only get the amount of steam that you

want. This way there is no loss of MJ into the air.

MJ is probably the most potent anti-cancer and anti-leukemia agent

known to man. And it is completely non-toxic to normal cells. You

can't say that about chemotherapy or radiation therapies. But it is

insoluble in water so the oral ingestion of MJ is out of the question.

So... the crazy people here at Grouppe Kurosawa figured out that MJ

could be introduced into the lungs (and blood) almost instantly if it

was in an aerosol form. MJ is a fragrance and is, by definition,

volatile. This inexpensive Vicks Inhaler is perfect for the job.

Not everything in life has to be complicated.

--------

Grouppe Kurosawa. Medicine in the Public Interest

http://www.grouppekurosawa.com/

posted by Dr. Steve at 7:59 AM 10 comments

Wednesday, December 05, 2007

The Medicinal Use of Methyl Jasmonate

This essay is reposted from our subscription blog in the public interest.

One of the members found an inexpensive source of MJ. Unfortunately,

it isn't as inexpensive as it sounds. This company does not

manufacture this product. They simply repackage it and sell to the

general public. That's fine...I have no complaints.

I do not believe that MJ needs to be taken daily nor should it. The

effective dose of MJ, which cannot be taken orally, is 3mM. This

" acute " dose will kill virtually every cancer or leukemia cell in the

body. Of course, we will use MJ with other products that will further

increase its effectiveness.

I believe we can use MJ in an aerosol form 5 times a month and that

should be sufficient. Remember, we do not want to induce a massive

necrosis in the body, but we need some cancer and leukemia cell

necrosis in order to activate both the innate and adaptive immune

responses. MJ, unlike virtually any other compound, serves two

purposes. It directly induces apoptosis and necrosis in malignant

cells, and it activates both innate and adpative immunity against the

remaining cancer/leukemia cells. Realistically, you can't ask for a

better anti-cancer/leukemia agent.

$12.50 seems inexpensive for 250 mgs of MJ, but at 2 grams five times

a month this equates to $500.00 a month. I can purchase it in bulk and

sell it for $170.00 a month, a significant cost savings.

http://www.phytotechlab.com/detail.aspx?ID=392

Nevertheless, 250 mgs of MJ could be quite beneficial if applied

topically in DMSO to a specific cancer, such as breast cancer. A

MJ/DMSO gel could also be applied up the nose for the treatment of

brain cancer.

For systemic cancers, MJ, a water insoluble compound, could be added

to the surface of very hot water. Since it is volatile, it will

rapidly enter the air. Gently put the MJ on the surface of a bowl of

hot water, put your face over it and wrap your head and the bowl in a

towel. Breathe deeply with both your nose and mouth. Any compound that

enters the lungs will rapidly be introduced into the blood. (see

following blog essay on the use of a personal steamer as a tool to

administer MJ).

MJ does not have to be taken for the rest of your life. A three month

treatment " may " be enough. Once the innate and adaptive immune

responses are activated, they should be able to control the cancer on

their own. Never forget the story of the cancer resistant mice. They

have super activated innate immune responses which makes them " immune "

to any and all cancers.

I will sell ten grams of MJ for $170. This is a one month supply. If I

receive orders for at least $2000 of MJ, I will order it. Otherwise, I

will not. I cannot afford to order products that people do not want.

Orders should be sent via PayPal to smartin@....

Simply notate MJ and the cost, $170 per month. If I do not receive the

appropriate orders for MJ within the next 30 days or so, I will refund

your money.

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

posted by Dr. Steve at 1:17 PM 3 comments

Tuesday, December 04, 2007

The Powerful Anti-Cancer and Anti-Leukemia Properties of Methyl Jasmonate

As discussed in a previous essay, one of the " wonders " of methyl

jasmonate as a anti-cancer agent is its ability to rapidly induce

necrosis. MJ accomplishes this goal by interfering the integrity of

the mitochondrial membrane of cancer but not normal cells. This

results in the release of cytochrome C and the initiation of the

apoptosis death process. MJ also inhibits ATP synthesis resulting in

necrosis. Although apoptosis can take 24 hours to promote death, it is

inhibited by a host of different genetic defects, such as those in the

p53 tumor suppressor gene. Necrosis can be initiated in seconds and is

COMPLETELY independent of defects in apoptosis inducing genes.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17549642 & itool=pubmed_docsum

Chemotherapy and radiation damage DNA in both cancer and normal cells.

This damage activates the p53 pathway and apoptosis is initiated.

Unfortunately, over half of all cancers and leukemias have

inactivating mutations in the p53 gene. Under these circumstances, the

cancer cells are resistant to both chemo drugs and radiation.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17230559 & itool=pubmed_docsum

The following study, which can be read online, is an excellent example

of how methyl jasmonate could potentially replace all forms of toxic

chemotherapy and radiation. Further, MJ is completely non-toxic to

normal cells.

In this study, two clones of a highly malignant B cell lymphoma were

selected for their p53 status. One line harbored a normal p53 gene

while the other expressed a mutated, inactive p53 protein. The cells

were treated independently with MJ, a chemo drug or a drug that was a

mimic of radiation. These treatments independently killed the lymphoma

cells harboring the normal p53 protein by initiating apoptosis.

However, the cells harboring the mutant p53 protein were NOT killed by

the chemo drug or radiation mimic. However, MJ did kill these highly

malignant, resistant cells by blocking oxidative phosphorylation

thereby drastically reducing ATP levels. Within seconds of a severe

ATP depletion, membrane pumps, which require ATP for activity, fail

causing the cells to swell and literally explode.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16170329 & itool=pubmed_docsum

Chronic lymphocytic leukemia is a very common, slow growing cancer

which is resistant to apoptosis. However, a subpopulation of fast

growing CLL cells is known to harbor the mutant p53 gene. This

mutation is predictive of the clinical course of the disease.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17707839 & itool=pubmed_docsum

MJ selectively kills CLL cells in the presence of normal lymphocytes.

It does so by depolarizing the mitochondrial membranes of leukemic but

not normal cells. Since the activity of MJ is independent of p53

status, it is an excellent treatment vehicle for p53 resistant

leukemia cells.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15753398 & itool=pubmed_docsum

This study of the effects of MJ on acute myeloid leukemia is very

interesting. AML is one of the worst forms of leukemia, because it is

largely resistant to chemo drugs and other forms of therapy.

AML blasts are immature myeloid cells. Experimentally, these cells can

be induced to differentiate into completely normal, functional myeloid

cells by a number of different chemicals. Unfortunately, many of these

chemicals are too toxic to be used clinically. MJ stopped the growth

of these blast cells and promoted their differentiation to completely

normal cells. And it did so at the incredibly low dose of 0.4mM.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15229618 & itool=pubmed_docsum

MJ kills lymphoma and leukemia cells without harming normal immune

functioning. Since MJ induces necrosis, an inflammatory process which

activates both innate and adaptive immunity by the release of HMGB1,

MJ acts as an indirect immune adjuvant as well.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15272298 & itool=pubmed_docsum

And it turns highly malignant AML blasts into normal cells.

Amazing.

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

posted by Dr. Steve at 10:02 AM 2 comments

Sunday, December 02, 2007

The Anti-Cancer Properties of Methyl Jamonates. Part One

This essay is republished from our subscription blog in the public

interest.

There is good news. I found a manufacturer of MJ that will sell to me

in bulk. The price is expensive but affordable, but it must be

imported. It is a pure product. There is only one manufacturer of this

product in the US and they won't sell to the public. Further, they

won't sell to me in bulk because we want to use the product for

medicinal purposes. They can't seem to grasp the concept that

fragrances might have a therapeutic value against a host of different

diseases. I get the impression that they are afraid of an FDA raid.

We will deal with these issues later. The following is a mini-review

of some of the anti-cancer properties of methyl jasmonate. Additional

essays will follow.

A scientific study published this month shows that MJ kills prostate

cancer cells via the inactivation of the 5-lipoxygenase enzyme. This

is a critical issue so we will review the biochemistry of 5-LOX

activation and cancer cell growth in this essay.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=18038760 & itool=pubmed_docsum

Products of the 5-LOX gene are involved in the growth of all cancers.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17762961 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17552358 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17434678 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=17220595 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16903934 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16462489 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16289380 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16250846 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16024599 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15944770 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15661803 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15637091 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15454480 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=15375079 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve &

dopt=Abstract & list_uids=15363593 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve &

dopt=Abstract & list_uids=15010818 & itool=pubmed_docsum

As these studies suggest, the combination of -2 and 5-LOX

inhibitors powerfully inhibits the growth of many different cancer and

leukemia cells. The combination of MJ and acetaminophen (Tylenol) can

accomplish this therapeutic goal.

Prostate cancer cells appear to be EXTREMELY sensitive to the

inhibition of the 5-LOX enzyme. As this study shows, 5-LOX inhibitors

can induce apoptosis/necrosis in extremely malignant prostate cancer

cells within hours.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=9789062 & itool=pubmed_docsum

5-LOX is also overexpressed in brain cancers. Since MJ must be applied

either topically in DMSO or via an aerosol, this makes MJ a PERFECT

treatment for brain cancers. There are no blood brain barrier problems

associated with the use of this product.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16462489 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=1357659 & itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstr\

act & list_uids=16708542 & itool=pubmed_docsum

There is MUCH more to discuss.

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

posted by Dr. Steve at 12:55 PM 2 comments

Wednesday, November 28, 2007

[Guest guest]

for myself.....I would rather stick to someting with a proven track record...if

time is off essence.....K

From: mcnjnj

The Anti-Cancer Fragrance Methyl Jasmonate Can Be Effectively

Introduced Into the Blood with a Simple Steam Inhaler........