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Re: Test tesults after Arimidex therapy

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Looks dam good you will know if your go to low your wood will stop.

Co-Moderator

Phil

> From: wayback44 <no_reply >

> Subject: Test tesults after Arimidex therapy

>

> Date: Thursday, August 28, 2008, 4:00 PM

> I just got back my lab test results (LabCorp/LEF). I am not

> on TRT at

> all, but have been taking Arimidex at the extremely low

> dose of 1/128

> mg/day, or roughly the equivalent of 1 mg every four

> months. I did not

> test T levels before starting Arimidex, but did do a

> baseline E2 test,

> which was also LabCorp. The baseline E2 was 48 pg/ml, and

> I believe

> that high level resulted from a blood pressure medicine I

> take. Well,

> here are the test results after one month on the current

> dose:

>

> Total Testosterone, Serum (241-827) 763 ng/dl

> Free Testosterone (Direct) (6.6-18.1) 17.1 pg/ml

> Estradiol (0-53) 21 pg/ml

>

> Well, I don't know what I would want to change. I

> think it looks

> pretty good. But it does show that some men may be very

> sensitive to

> aromatase inhibitors, so you really do have to test every

> now and then

> to make sure you aren't taking E2 too low.

>

>

>

>

>

> ------------------------------------

>

>

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Hi WB,

Could you explain about your comment " that high level resulted from a

blood pressure medicine I take "

I missed the memo on that!

Neil

wayback44 wrote:

>

>

> I just got back my lab test results (LabCorp/LEF). I am not on TRT at

> all, but have been taking Arimidex at the extremely low dose of 1/128

> mg/day, or roughly the equivalent of 1 mg every four months. I did not

> test T levels before starting Arimidex, but did do a baseline E2 test,

> which was also LabCorp. The baseline E2 was 48 pg/ml, and I believe

> that high level resulted from a blood pressure medicine I take. Well,

> here are the test results after one month on the current dose:

>

> Total Testosterone, Serum (241-827) 763 ng/dl

> Free Testosterone (Direct) (6.6-18.1) 17.1 pg/ml

> Estradiol (0-53) 21 pg/ml

>

> Well, I don't know what I would want to change. I think it looks

> pretty good. But it does show that some men may be very sensitive to

> aromatase inhibitors, so you really do have to test every now and then

> to make sure you aren't taking E2 too low.

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG.

> Version: 7.5.524 / Virus Database: 270.6.11/1639 - Release Date: 8/28/2008

7:39 AM

>

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I have to say that I don't have complete proof of this, but I have read

that the two older calcium channel blockers diltiazem and verapamil

moderately suppress the enzymes which are responsible for metabolizing

(removing from the body) estradiol and perhaps other estrogens. The

result is that estrogen levels tend to increase for those taking these

drugs for blood pressure. I take the maximum dose of diltiazem, which

works really well for my blood pressure, and seems not to have any

other adverse effects, so I would like to keep taking it. Nothing else

I've tried does much good.

This does not apply to the newer dihydropyridine CCBs, including

Norvasc.

In techincal terms, the two older CCBs are moderate inhibitors of CYP-

3A4, and perhaps other enzymes that are involved in estrogen

metabolism. They slow down the removal of estrogens from the body.

They were listed as problematic drugs in Shippen's book, and both may

cause gynecomastia in a very small number of men (whose E2 levels are

presumably already high).

>

> Hi WB,

>

> Could you explain about your comment " that high level resulted from

a

> blood pressure medicine I take "

>

> I missed the memo on that!

>

> Neil

>

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Hi WB,

Nothing wrong with having an opinion! :-)

I was concerned though, I take Lisinopril and got freaked out for a minute!

You didn't mention that drug....so that means I'm OK????

Neil

wayback44 wrote:

>

> I have to say that I don't have complete proof of this, but I have read

> that the two older calcium channel blockers diltiazem and verapamil

> moderately suppress the enzymes which are responsible for metabolizing

> (removing from the body) estradiol and perhaps other estrogens. The

> result is that estrogen levels tend to increase for those taking these

> drugs for blood pressure. I take the maximum dose of diltiazem, which

> works really well for my blood pressure, and seems not to have any

> other adverse effects, so I would like to keep taking it. Nothing else

> I've tried does much good.

>

> This does not apply to the newer dihydropyridine CCBs, including

> Norvasc.

>

> In techincal terms, the two older CCBs are moderate inhibitors of CYP-

> 3A4, and perhaps other enzymes that are involved in estrogen

> metabolism. They slow down the removal of estrogens from the body.

> They were listed as problematic drugs in Shippen's book, and both may

> cause gynecomastia in a very small number of men (whose E2 levels are

> presumably already high).

>

>

> >

> > Hi WB,

> >

> > Could you explain about your comment " that high level resulted from

> a

> > blood pressure medicine I take "

> >

> > I missed the memo on that!

> >

> > Neil

> >

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG.

> Version: 7.5.524 / Virus Database: 270.6.11/1639 - Release Date: 8/28/2008

7:39 AM

>

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Share on other sites

How did you divide the Arimidex pill into 128 parts?

>

>

> I just got back my lab test results (LabCorp/LEF). I am not on TRT

at

> all, but have been taking Arimidex at the extremely low dose of

1/128

> mg/day, or roughly the equivalent of 1 mg every four months. I did

not

> test T levels before starting Arimidex, but did do a baseline E2

test,

> which was also LabCorp. The baseline E2 was 48 pg/ml, and I

believe

> that high level resulted from a blood pressure medicine I take.

Well,

> here are the test results after one month on the current dose:

>

> Total Testosterone, Serum (241-827) 763 ng/dl

> Free Testosterone (Direct) (6.6-18.1) 17.1 pg/ml

> Estradiol (0-53) 21 pg/ml

>

> Well, I don't know what I would want to change. I think it looks

> pretty good. But it does show that some men may be very sensitive

to

> aromatase inhibitors, so you really do have to test every now and

then

> to make sure you aren't taking E2 too low.

>

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Share on other sites

I was wondering that myself. Must be Liquidex.

Re: Test tesults after Arimidex therapy

How did you divide the Arimidex pill into 128 parts?

>

>

> I just got back my lab test results (LabCorp/LEF) . I am not on TRT

at

> all, but have been taking Arimidex at the extremely low dose of

1/128

> mg/day, or roughly the equivalent of 1 mg every four months. I did

not

> test T levels before starting Arimidex, but did do a baseline E2

test,

> which was also LabCorp. The baseline E2 was 48 pg/ml, and I

believe

> that high level resulted from a blood pressure medicine I take.

Well,

> here are the test results after one month on the current dose:

>

> Total Testosterone, Serum (241-827) 763 ng/dl

> Free Testosterone (Direct) (6.6-18.1) 17.1 pg/ml

> Estradiol (0-53) 21 pg/ml

>

> Well, I don't know what I would want to change. I think it looks

> pretty good. But it does show that some men may be very sensitive

to

> aromatase inhibitors, so you really do have to test every now and

then

> to make sure you aren't taking E2 too low.

>

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Some men get there arimidex compounded and there is a site that sell a LiquiDex.

You would need to send me an Emile for the link to the site.

Co-Moderator

Phil

> From: gin2c <no_reply >

> Subject: Re: Test tesults after Arimidex therapy

>

> Date: Friday, August 29, 2008, 9:03 AM

> How did you divide the Arimidex pill into 128 parts?

>

>

>

>

>

> >

> >

> > I just got back my lab test results (LabCorp/LEF). I

> am not on TRT

> at

> > all, but have been taking Arimidex at the extremely

> low dose of

> 1/128

> > mg/day, or roughly the equivalent of 1 mg every four

> months. I did

> not

> > test T levels before starting Arimidex, but did do a

> baseline E2

> test,

> > which was also LabCorp. The baseline E2 was 48 pg/ml,

> and I

> believe

> > that high level resulted from a blood pressure

> medicine I take.

> Well,

> > here are the test results after one month on the

> current dose:

> >

> > Total Testosterone, Serum (241-827) 763

> ng/dl

> > Free Testosterone (Direct) (6.6-18.1) 17.1

> pg/ml

> > Estradiol (0-53) 21

> pg/ml

> >

> > Well, I don't know what I would want to change. I

> think it looks

> > pretty good. But it does show that some men may be

> very sensitive

> to

> > aromatase inhibitors, so you really do have to test

> every now and

> then

> > to make sure you aren't taking E2 too low.

> >

>

>

>

> ------------------------------------

>

>

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I bought " generic " anastrozole in liquid form from Innovative Research,

1 mg/ml, and further dilute that 16x, so that it's 1 mg per 16 ml.

then I take .125 ml of that solution every day with an oral syringe.

>

> How did you divide the Arimidex pill into 128 parts?

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I don't know about lisinopril. It's a completely different class of

drug, and I don't know of any E2 effect from it.

>

> Hi WB,

>

> Nothing wrong with having an opinion! :-)

>

> I was concerned though, I take Lisinopril and got freaked out for a

minute!

>

> You didn't mention that drug....so that means I'm OK????

>

> Neil

>

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