Re: TOTAL T vs Bioavailable T ?

[Guest guest]

Here is a cut & amp; paste about this from this site.

http://www.t-nation.com/readTopic.do?id=460554

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However, when in the blood, 60% of the big T released from the boys down below

is bound up by a protein known as SHBG, or sex-hormone binding globulin. SHBG is

produced and released by the liver. The important point is that the Testosterone

bound to SHBG is biologically inactive and this is why there's an important

distinction between total T and bioavailable T.

Total T represents all the Testosterone in the blood, while bioavailable T

represents the non SHBG bound Testosterone. There are other proteins in the

blood that bind Testosterone, too, but their binding is rather weak, so this T

is bioavailable and these proteins can still enter the cells to produce and

effect all the things we're interested in.

As I said, bioavailable T represents the Testosterone that is not SHBG bound,

while free T represents the Testosterone that's not bound to any blood proteins

at all. It's tricky, I know, but I hope that it's now evident that although only

about 2% of the T in blood is technically considered free T, there is a larger

percentage of T (about 40% or so) that is bioavailable because it's only weakly

bound to non SHBG blood proteins.

Co-Moderator & amp;quot;Don & amp;#39;t believe anything you hear and only half of

what you see. & amp;quot;

Phil

From: manraj2005 & lt;manraj2005@... & gt;

Subject: TOTAL T vs Bioavailable T ?

Date: Thursday, June 5, 2008, 11:50 AM

Hi

I was just wandering can someone explain to me the difference in the

measurements of these 2 variables and what exactly they are measuring

and talking about?

Thank you

Manraj

[Guest guest]

Hi Phil

thanks for the post !!!! makes much more sense now.

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> From: manraj2005 manraj2005@...

> Subject: TOTAL T vs Bioavailable T ?

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> Date: Thursday, June 5, 2008, 11:50 AM

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> I was just wandering can someone explain to me the difference in

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> measurements of these 2 variables and what exactly they are

measuring

> and talking about?

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> Thank you

> Manraj

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[Guest guest]

Great thats what we are here for.

Co-Moderator & amp;quot;Don & amp;#39;t believe anything you hear and only half of

what you see. & amp;quot;

Phil

From: manraj2005 & lt;manraj2005@... & gt;

Subject: Re: TOTAL T vs Bioavailable T ?

Date: Thursday, June 5, 2008, 4:18 PM

Hi Phil

thanks for the post !!!! makes much more sense now.

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& gt; From: manraj2005 manraj2005@. ..

& gt; Subject: TOTAL T vs Bioavailable T ?

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& gt; Date: Thursday, June 5, 2008, 11:50 AM

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& gt; Hi

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& gt; I was just wandering can someone explain to me the difference in

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& gt; Thank you

& gt; Manraj

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