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Thank you and ....you both made me feel really good and

just in time too....I'm sitting around dreading tonight when I take

the MTX for the first time. I'm so afraid of the fatigue people are

talking about. I'm so tired now with the PA and two young children

that I can not imagine being more tired.

Is there anything that can combat the fatigue (other than rest)?

best to all....

[Glad to have been of any help at all. And, if this is of use (case studies are

all we've got, huh?): I've been taking Methotrexate (15 to 25 mg) for 23 years.

(Searching for wood....there, knock knock.)I've never been nauseous, never had

any fatigue. Just another %$^ & ^% pill or two. I do remember how long I lay there

(I was having one of those delightful flares, and was confined to bed) , staring

at those little pills, for the first time, with all the warnings running around

in my head, then finally taking the plunge. That was back in the day when you

had to have a liver biopsy every couple of years you were on it. Thankfully,

experience has shown that, in the PA and RA doses, it's considerably safer than

originally thought.

So: Maybe you'll be like me, and there won't be a bit of difference, before and

after taking it! I sure hope so.

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