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Re: Re: MTX usage*

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Janet,

I've been taking MTX since 1994, I take 10 (25mgs) each week. I've never had

any ill effects from it. So maybe you won't either. Good luck. Other then

the fatigue, MTX has been a good med for me. I got relief from the fatigue when

I went on Enbrel a couple of years ago.

Becky Raine

Hi Marti,

I started the mtx this evening. the rheumy started me on 4 pills and I took

two after dinner and will take the other two when I go to sleep. Can anyone

tell me when the nausea usually starts after taking the pills.

Janet

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In a message dated 8/21/2003 4:10:07 AM Eastern Daylight Time,

braine@... writes:

> Janet,

>

> I've been taking MTX since 1994, I take 10 (25mgs) each week. I've never

> had any ill effects from it. So maybe you won't either.

I spoke too soon Becky but the side effects I have are not horrible. I took

the mtx on Tuesday and since then I have been a little quesy but not horrible.

I have no additional fatigue. I do have the worst taste in my mouth kind of

like a metallic taste (bitter). I looked up mtx in some sites and cannot find

any side effects listed like this. Does anyone have this??

Janet

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This is interesting to me. I am wondering if that metallic taste a few of

you have mentioned is the MTX itself or a shift in hormone levels such as

cortisol and/or adrenaline caused by the MTX? A metallic taste likened to

sucking

on a copper penny is sometimes associated with significant releases of

adrenaline. I dont know if you could actually taste elevated cortisol levels

but the

salivary glands do a good job of concentrating cortisol and as such a fairly

accurate serum cortisol level can be determined by measuring the cortisol

content in saliva. Didnt one of our female members mention that her spouse

could

predict her impending flare based on the flavor of a kiss or was it the smell

on the breath? Orin

In a message dated 8/22/03 3:12:09 AM Central Daylight Time, fam24@...

writes:

> I spoke too soon Becky but the side effects I have are not horrible. I

> took

> the mtx on Tuesday and since then I have been a little quesy but not

> horrible.

> I have no additional fatigue. I do have the worst taste in my mouth kind of

>

> like a metallic taste (bitter). I looked up mtx in some sites and cannot

> find

> any side effects listed like this. Does anyone have this??

> Janet

>

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  • 4 weeks later...

I personally take Protonix, which helps tremendously with the nausea. I also

know that our founder recommends Zofran, which is an antiemetic.

Also, if you are taking MTX orally, you might want to consider going to

injections

instead. A lot of people, including me tolerate the MTX injections better

than oral medication. I still get a little tired the next day, but at least I

don't feel like I'm recovering from a week-long drinking binge.

Hope this helps.

Carol in Vancouver, Washington

In a message dated 9/16/03 2:39:26 AM Pacific Daylight Time,

intothavoid1@... writes:

I have been taking MTX since 97'. Recently the nausea and headaches

have gotten worse. I have to take the weekly dose Friday evenings

because I am unable to function the next morning. The 'hangover'

and 'fog' lasts most of Saturday. Tylenol does not touch the headache.

Is there a med that could help with the headache and nausea?

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