Guest guest Posted July 16, 2008 Report Share Posted July 16, 2008 prednisone is a very bad treatment with many side effects.the ldn might help also with the antibodies.if it is possible the the best is to use only ldn. > > Is LDN a better alternative to prednisone(10mg). I was prescribed > prednisone for ANA and antibodies. I was prescibed LDN for anxiety and > other issues.Are the two drugs treating the same thing or are they for > different purpose? Will there be side effects if I take both? I am > trying to conceive. > > Thanks! > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 16, 2008 Report Share Posted July 16, 2008 > > > > > Is LDN a better alternative to prednisone(10mg). I was prescribed > > prednisone for ANA and antibodies. I was prescibed LDN for anxiety > and > > other issues.Are the two drugs treating the same thing or are they > for > > different purpose? Will there be side effects if I take both? I am > > trying to conceive. > > > > Thanks! > > *********************************************** I took Prednisone on 2 different occassions (many years ago) to reduce inflammation and had bad side effects (mood swings, moon face, etc.). This occurs when taking it on a " long-term " basis. Since taking it back then, I have refused to take it. It is my understanding that Prednisone can be taken in low dose (10 mg or less) on a short-term basis to assist with Crohn's flares, etc. (inflammation) and it can be taken in low dose with LDN. If it were " my choice " I would go with the LDN only but the decision is yours. Best of luck to you! Kindly, Patti (a/k/a livinwithcrohns) *dx Crohn's - June 1978 *surgery - Dec. 2002 - Ileocolectomy/resection *dx Crohn's/Colitis/Acid Reflux - Feb. 2005 (2006) *4.5 mg LDN user since March 2008 " History is made by those who do not go blindly into the night... " [ L. Ware, Private Investigator - 5/14/08 The Daily Advisor] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2008 Report Share Posted July 17, 2008 Why would they prescribe prednisone for positive ANA antibodies? I have lupus and they will only prescribe me these medications if I have enough symptoms to warrant the treatment. The level of ANA antibodies rarely reflects the degree of activity in the disease. I could be 1:1280 and have zero symptoms or 1:320 and having serious pain issues. Prednisone has many, many side effects ranging from annoying (acne, mood swings, weight gain) to dangerous (osteoporosis, liver problems, etc.). If you do not have symptoms, you should slowly wean yourself off of the prednisone. Do you mind if I ask if you had symptoms before being prescribed this? I would assume yes if they thought to check for the positive antibodies. LDN should regulate both, and it's not good to be taking both together. A normal maintenance dose for lupus and some other autoimmune on Prednisone is around 7-10 mg. 7 mg is considered what your body normally produces, but there are still a lot of side effects for various reasons (one of which being that the drug is a synthetic and not a natural cortisol). Higher dosages in the thousands of mg have been used for crises, but not generally long term. Your dosage sounds standard for autoimmune maintenance, but without more background, I can't tell you if you should have ever been on both. Cami Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2008 Report Share Posted July 17, 2008 Thanks everyone for your reply. A reproductive immunologist prescribed prednisone and I am really uncomfortable taking it after reading the side effects although there are some people who do get pregnant.They usually test for ANA and also antithyroid antibodies because they believe these factors can cause miscarriage. My ATA is going down. Another catholic doctor prescribed LDN. I seem okay with LDN although it seem to be more expensive than prednisone like about $20 over for a month's supply whereas predisone is like maybe $2. So does LDN have the exact same benefit of helping the antibodies with out the side effects of prednisone. Am I right? I plan to ask my doctor to refill my LDN when I meet him again. Thanks! > > Why would they prescribe prednisone for positive ANA antibodies? I have lupus and they will only prescribe me these medications if I have enough symptoms to warrant the treatment. The level of ANA antibodies rarely reflects the degree of activity in the disease. I could be 1:1280 and have zero symptoms or 1:320 and having serious pain issues. Prednisone has many, many side effects ranging from annoying (acne, mood swings, weight gain) to dangerous (osteoporosis, liver problems, etc.). If you do not have symptoms, you should slowly wean yourself off of the prednisone. > > Do you mind if I ask if you had symptoms before being prescribed this? I would assume yes if they thought to check for the positive antibodies. > > LDN should regulate both, and it's not good to be taking both together. > > A normal maintenance dose for lupus and some other autoimmune on Prednisone is around 7-10 mg. 7 mg is considered what your body normally produces, but there are still a lot of side effects for various reasons (one of which being that the drug is a synthetic and not a natural cortisol). Higher dosages in the thousands of mg have been used for crises, but not generally long term. Your dosage sounds standard for autoimmune maintenance, but without more background, I can't tell you if you should have ever been on both. > > Cami > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2008 Report Share Posted July 17, 2008 if the prednisone is related to become pregnant,then it make a lot of sense.we have this experince. > > > > Why would they prescribe prednisone for positive ANA antibodies? I > have lupus and they will only prescribe me these medications if I have > enough symptoms to warrant the treatment. The level of ANA antibodies > rarely reflects the degree of activity in the disease. I could be > 1:1280 and have zero symptoms or 1:320 and having serious pain issues. > Prednisone has many, many side effects ranging from annoying (acne, > mood swings, weight gain) to dangerous (osteoporosis, liver problems, > etc.). If you do not have symptoms, you should slowly wean yourself > off of the prednisone. > > > > Do you mind if I ask if you had symptoms before being prescribed > this? I would assume yes if they thought to check for the positive > antibodies. > > > > LDN should regulate both, and it's not good to be taking both together. > > > > A normal maintenance dose for lupus and some other autoimmune on > Prednisone is around 7-10 mg. 7 mg is considered what your body > normally produces, but there are still a lot of side effects for > various reasons (one of which being that the drug is a synthetic and > not a natural cortisol). Higher dosages in the thousands of mg have > been used for crises, but not generally long term. Your dosage sounds > standard for autoimmune maintenance, but without more background, I > can't tell you if you should have ever been on both. > > > > Cami > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 17, 2008 Report Share Posted July 17, 2008 Cami, I forgot to add.I actually had bad IBS problems 2-4 years ago but after doing a lot of detoxing and alternative treatments I am much better now. I believe I may still have infections which caused these IBS problems and this may be affecting me to TTC for 3 years.My ANA Titer last tested in Jun 08 was 1:160 Homeogeneous(autoantibodies to nDNA, DNA-histone complexes or deoxyribonucleoprotein) and ANA Titer 2 1:80 speckled which is suggestive of antoantibodies to Sm, RNP, Scl-70, SSA, SSb or other extractable nuclear antigens. My rhematologist testings came back negative but when I tested with Reproductive immunologist, they say this can affect implantation.I did not have any pain when I tested with her in Nov last year but recently because I also started taking lovenox(blood thinner) I have started to get pain on my left knee on the back and also on my righthand below my thumb. Is this due to arthritis? I need to check with doctor why I am having this pain. Thanks for your help! > > Why would they prescribe prednisone for positive ANA antibodies? I have lupus and they will only prescribe me these medications if I have enough symptoms to warrant the treatment. The level of ANA antibodies rarely reflects the degree of activity in the disease. I could be 1:1280 and have zero symptoms or 1:320 and having serious pain issues. Prednisone has many, many side effects ranging from annoying (acne, mood swings, weight gain) to dangerous (osteoporosis, liver problems, etc.). If you do not have symptoms, you should slowly wean yourself off of the prednisone. > > Do you mind if I ask if you had symptoms before being prescribed this? I would assume yes if they thought to check for the positive antibodies. > > LDN should regulate both, and it's not good to be taking both together. > > A normal maintenance dose for lupus and some other autoimmune on Prednisone is around 7-10 mg. 7 mg is considered what your body normally produces, but there are still a lot of side effects for various reasons (one of which being that the drug is a synthetic and not a natural cortisol). Higher dosages in the thousands of mg have been used for crises, but not generally long term. Your dosage sounds standard for autoimmune maintenance, but without more background, I can't tell you if you should have ever been on both. > > Cami > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2008 Report Share Posted July 18, 2008 Initially my antibodies increased, but it appears LDN may bring out candida in the system (others seem to experience something similar). After being treated with Nystatin for intestinal overgrowth, the antibodies actually greatly decreased (from 1:1280 to 1:640). It's still early on and I just increased to a full 4.5 mg last night, so I can't know for sure. It sounds like others have had success with lowering ANA levels with LDN alone. $20 a month is a very cheap treatment. In addition to LDN, I take a lot of allergy shots, supplements (liquid, pill and injectable) and spend big bucks on food. It's important to consider allergies, yeast, etc. Cami Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2008 Report Share Posted July 18, 2008 We have some things in common I had a lot of childhood problems that calmed down, but started out with IBS problems and they morphed into more autoimmune problems. Just today I went to a doctor I trust very much who is an M.D. and specializes in environmental medicine. He tested me for many allergies, and boy do I have a lot! I'm allergic to foods, dander, dust, plus odd things like plastics and the mold/fungus that occurs naturally in very small amounts on our skin. I have to do a total overhaul on my lifestyle. It is overwhelming, but I started a new diet plan weeks ago and it is really helping. I took a spit hormone test (have you had this done?) and the patterns were very strange. He wondered if I was allergic to my own hormones, and sure enough, I seem to be allergic to my estrodiol. I know this doesn't sound possible, but it is. Do you have access to this kind of testing? It may be helpful for you if you are trying to be pregnant. Now did you test positive for all of these autoantibodies, or did they simply do the ANA by IFA that separates into different pattern types? If you were not specifically tested for anti-nDNA and SSA, SSb, then I'm not sure how you can be certain you are positive. I have a 1:640 (was 1:1280) speckled, but have not actually tested positive for the SSA or SSb nuclear antigens (so far as I know). You sound very read up on all of this which is fantastic I fear we are going very off topic but please e-mail me directly. I would love to discuss this all with you as it appears I will also have a very hard time having children (unless LDN helps that as well Take Care, Cami Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2008 Report Share Posted July 18, 2008 Hi , Sorry to jump in here without seeing any previous posts or getting more background info. I'm just going to base this on your last post ... Everyone trying to get pregnant should be supplementing with the RDA of Folic Acid. There are supplement combos available at most pharmacies that include the recommended daily doses of Folic Acid, iodine, etc for prospective mums. If you've had more than one miscarriage, your doctor should have ordered some tests to determine cause. Did he? In particular, he should have checked your Folic Acids levels - because if they're low they can cause miscarriage. I learned this from personal experience. I had two miscarriages, followed by a Dilatation & Curettage before my low Folic Acid was found. I was then able to supplement prior to and during every pregnancy - without any further problems. My personal opinion is that this is an important first step that's gone missing from the doctor's deskpad - that simple blood test resulted in my taking a daily supplement that cost around $2 month and gave me three beautiful children! Kind regards, Cris 14a. Re: LDN vs prednisone Posted by: " angelinevic " angelinevic@... angelinevic Date: Thu Jul 17, 2008 12:47 pm ((PDT)) Thanks everyone for your reply. A reproductive immunologist prescribed prednisone and I am really uncomfortable taking it after reading the side effects although there are some people who do get pregnant.They usually test for ANA and also antithyroid antibodies because they believe these factors can cause miscarriage. My ATA is going down. Another catholic doctor prescribed LDN. I seem okay with LDN although it seem to be more expensive than prednisone like about $20 over for a month's supply whereas predisone is like maybe $2. So does LDN have the exact same benefit of helping the antibodies with out the side effects of prednisone. Am I right? I plan to ask my doctor to refill my LDN when I meet him again. Thanks! > > Why would they prescribe prednisone for positive ANA antibodies? I have lupus and they will only prescribe me these medications if I have enough symptoms to warrant the treatment. The level of ANA antibodies rarely reflects the degree of activity in the disease. I could be 1:1280 and have zero symptoms or 1:320 and having serious pain issues. Prednisone has many, many side effects ranging from annoying (acne, mood swings, weight gain) to dangerous (osteoporosis, liver problems, etc.). If you do not have symptoms, you should slowly wean yourself off of the prednisone. > > Do you mind if I ask if you had symptoms before being prescribed this? I would assume yes if they thought to check for the positive antibodies. > > LDN should regulate both, and it's not good to be taking both together. > > A normal maintenance dose for lupus and some other autoimmune on Prednisone is around 7-10 mg. 7 mg is considered what your body normally produces, but there are still a lot of side effects for various reasons (one of which being that the drug is a synthetic and not a natural cortisol). Higher dosages in the thousands of mg have been used for crises, but not generally long term. Your dosage sounds standard for autoimmune maintenance, but without more background, I can't tell you if you should have ever been on both. > > Cami Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 21, 2008 Report Share Posted July 21, 2008 Thanks Cami, I might ask my doctor for Nystatin.Hopefully that will bring the ANA down. I also have nail fungus and a bit of white tongue > > Initially my antibodies increased, but it appears LDN may bring out candida in the system (others seem to experience something similar). After being treated with Nystatin for intestinal overgrowth, the antibodies actually greatly decreased (from 1:1280 to 1:640). It's still early on and I just increased to a full 4.5 mg last night, so I can't know for sure. It sounds like others have had success with lowering ANA levels with LDN alone. > > $20 a month is a very cheap treatment. In addition to LDN, I take a lot of allergy shots, supplements (liquid, pill and injectable) and spend big bucks on food. It's important to consider allergies, yeast, etc. > > Cami > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 21, 2008 Report Share Posted July 21, 2008 Thanks Cris, I do take extra folic acid of 2000mg on top of my prenatal and lots of other supplements like iodine etc. Not a BFP in 3 years. My next step will be doing a lap. > > > > Why would they prescribe prednisone for positive ANA antibodies? I > have lupus and they will only prescribe me these medications if I have > enough symptoms to warrant the treatment. The level of ANA antibodies > rarely reflects the degree of activity in the disease. I could be > 1:1280 and have zero symptoms or 1:320 and having serious pain issues. > Prednisone has many, many side effects ranging from annoying (acne, > mood swings, weight gain) to dangerous (osteoporosis, liver problems, > etc.). If you do not have symptoms, you should slowly wean yourself > off of the prednisone. > > > > Do you mind if I ask if you had symptoms before being prescribed > this? I would assume yes if they thought to check for the positive > antibodies. > > > > LDN should regulate both, and it's not good to be taking both together. > > > > A normal maintenance dose for lupus and some other autoimmune on > Prednisone is around 7-10 mg. 7 mg is considered what your body > normally produces, but there are still a lot of side effects for > various reasons (one of which being that the drug is a synthetic and > not a natural cortisol). Higher dosages in the thousands of mg have > been used for crises, but not generally long term. Your dosage sounds > standard for autoimmune maintenance, but without more background, I > can't tell you if you should have ever been on both. > > > > Cami > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 22, 2008 Report Share Posted July 22, 2008 Hi Angel, My ANA antibodies came down with LDN alone. Maybe you could try LDN first... and see how it does...then make a decision about Prednisone later. Best wishes... Jann Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.