Guest guest Posted December 21, 2003 Report Share Posted December 21, 2003 My fiend has a large size tumor on his kidney. I's like to use alternative to surgery to kill it. Has anyone done this? sincerely gp Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2003 Report Share Posted December 22, 2003 GP, Radiofrequency ablation (RFA) can be used very effectively for kidney tumors. This can be done with some of the progesterones, e.g., hydroxyprogesterone or megace. Dipyridamole 300mg and cimetidine 1,200 mg per day --> 80% remission in one study but I haven't been able to verify. IL-2 can be used with Naltrexone (below). Neuroendocrinol Lett 2002 Jun;23(3):255-8 A new neuroimmunotherapeutic strategy of subcutaneous low-dose interleukin-2 plus the long-acting opioid antagonist naltrexone in metastatic cancer patients progressing on interleukin-2 alone. Lissoni P, Malugani F, Bordin V, Conti A, Maestroni G, Tancini G. Division of Radiation Oncology, S. Gerardo Hospital, Monza, Milan, Italy. OBJECTIVES: Recent advances in knowledge of Psychoneuroimmunology have shown that several neuroactive substances, including neurohormones and neuropeptides, may exert immunomodulatory effects. However, despite the great variety of potential neuroimmune interactions, at present we may recognize two major neuroendocrine systems exerting a physiological neuroimmunomodulatory function, consisting of the pineal gland and the brain opioid system, provided by immunostimulatory and immunosuppressive effects, respectively. Recent in human studies have demonstrated the possibility to amplify the biological activity of IL-2, the major anticancer cytokine, by pineal indoles. MATERIALS & METHODS: The present study was carried out to draw some preliminary in human results on the possible immunomodulatory effects of the inhibition of the brain opioid activity by a long-acting opioid antagonist, naltrexone (NTX). The study was performed in 10 metastatic renal cell cancer patients, who had progressed on a previous immunotherapeutic cycle with IL-2 alone. Patients were treated with the same doses of IL-2 (6 million lU/day subcutaneously for 6 days/week for 4 weeks) plus an oral administration of NTX at a dose of 100 mg every 2 days. RESULTS: The clinical response consisted of a partial response in 1 and a stable disease in 5 patients, whereas the other 4 patients progressed. Therefore, the percent of non-progressive disease was 6/10 (60%). Moreover, mean lymphocyte increase achieved during IL-2 plus NTX was significantly higher (P<0.05) than that obtained during the previous treatment with IL-2 alone. CONCLUSIONS: This study shows that a blockade of the brain opioid system, which plays a physiological immunosuppressive role, may improve the anticancer effects of IL-2 in humans. [ ] need help curing a kidney tumor > My fiend has a large size tumor on his kidney. I's like to use > alternative to surgery to kill it. Has anyone done this? > > sincerely gp > Quote Link to comment Share on other sites More sharing options...
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