Re: Iodine Patch Test

[Guest guest]

Hi - I live in Australia and cant get the iodine test here. So I am doing the

patch tests. (Fortunately I can get Iodine tincture because that is becoming

hard to get here as well because evidently can be turned into an explosive).

Someone mentions it is not reliable or accurate. There is nothing in

Brownstein's book about it, much to my disappointment.

I tested myself prior to Iodoral and it lasted 3 hours. After 1 week on 1

tablet a day it lasted 8 hours and now after my second week on 1 tab it lasted 8

hours again. So next week I will step up to 2. I must say it seems to be a

fairly good indicator. Does anyone know any websites that mention it?

Do you think what I am doing is reasonable?

Toni

[Guest guest]

Just wondering if you've found any information on this test that isn't 80 years

old? As you know science has changed dramatically and there may be other

opinions out there.

Tami

________________________________

From: Chuck B <gumboyaya@...>

hypothyroidism

Sent: Tue, September 7, 2010 7:04:25 PM

Subject: Iodine patch test

Tami,

You wrote:

>

> Have you read anything newer than 1932? Believe anything new or

> historical for

> that matter?

>

Sure, and this well established paper continues to be cited. No

experiment has challenged the results. It was significant in showing

that a percentage of any drug can be absorbed through healthy skin, but

the amount is completely independent of thyroid status and depends on

diffusion only. In the case of iodine, most of it evaporates, which

depends on humidity and temperature but most definitely not on an iodine

deficiency.

This was Dr. Derry's comment a couple of years ago on the 1932

paper relayed through Shomon:

[begin quote]

The " test " of putting iodine on the skin to watch how fast it disappears

is not an indicator of anything. The iodine disappearance rate is

unrelated to thyroid disease or even iodine content of the body.(1-2)

Meticulous research by Nyiri and Jannitti in 1932 showed clearly when

iodine is applied to the skin in almost any form, 50% evaporates into

the air within 2 hours and between 75 and 80 percent evaporates into the

air within 24 hours. (1) A total of 88 percent evaporates within 3 days

and it is at this point that the evaporation stops. The remaining 12

percent that is absorbed into the skin has several fates. Only 1-4% of

the total iodine applied to the skin is absorbed into the blood stream

within the first few hours. The rest of the iodine within the skin

(8-11%) is slowly released from the skin into the blood stream. [end quote]

1. Nyiri,W., Jannitti,M.. About the fate of free iodine upon application

to the unbroken animal skin. J Pharmacol Exp Ther 45:85-107, 1932.

2. Biskind,M.S. Penetration through tissue of iodine in different

solvents. Proc Soc Exp Biol Med 30:35-37, 1932.

Abstract of the original 1932 paper, which has not been disputed:

The paper deals with the fate of free iodine upon application to the

unbroken animal skin. The experiments were made on rabbits and dogs, and

gave the following results:

1. Free iodine pentrates through the unbroken skin. This penetration

only takes place in the form of compounds. Iodine upon external

application was detected (/a/) in the urine of dogs, (/b/) on the inner

surface of the pouched rabbit skin, (/c/) in the efferent blood vessels

of the perfused isolated rabbit ear.

2. Quantitative experiments made on rabbits concerning penetration,

absorption and evaporation of iodine offer a fair conception concerning

the fate of iodine applied to the surface of animal skin:

/a./ Approximately 88 per cent of the iodine evaporate from the surface

within three days. The rate of evaporation is highest within the first

few minutes after application. Within the first two hours 50 per cent of

the material escape into the air; at the end of twenty-four hours the

loss amounts to about 75 to 80 per cent; only small amounts evaporate

during the second day, and even less during the third day. The

evaporation ceases after this time.

/b./ The rest, approximately 12 per cent is at the disposal of the body,

and penetrates through the skin. The removal of these 12 per cent into

the body is very gradual. Only 1 to 4 per cent are absorbed within the

first few hours. The rest forms a depôt in the skin from which about 5

to 6 per cent are taken up within three days. The remaining 3 to 5 per

cent are gradually absorbed after this time.

3. Following application to the skin of the dog, 1 to 3 per cent of

iodine are excreted in the urine within three days. Although this

percentage is very low, it suggests that the fate of iodine in the dog

is similar to that in the rabbit, considering the slow rate of urinary

excretion following various modes of administration, and the marked

iodine storing power of the body.

4. The percentage of iodine penetration through the skin is the same,

irrespective of whether the cells have a high or low vitality, or are

dead, and irrespective of the direction of penetration. Activity of the

cells, therefore, does not seem to be indispensable for the penetration

of iodine.

5. The fate of iodine in all above experiments is the same whether

iodine is applied to the skin in the form of an alcoholic solution or in

colloidal suspension.

6. When the isolated ear and isolated kidney of rabbits are perfused at

a moderate rate with a solution containing free iodine, the iodine is

quantitatively reduced to iodides.

Chuck

[Guest guest]

On 9/8/2010 11:39 AM, Tami wrote:

>

> Just wondering if you've found any information on this test that isn't

> 80 years

> old? As you know science has changed dramatically and there may be other

> opinions out there.

>

The 1932 paper has been cited repeatedly, as recently as last year that

I know of. Most of the citations were in the 1950s through the 1990s.

Not one research paper contradicted it or presented experimental

evidence that did not support it. The quotations from Shomon and

Dr. Derry that I posted were from 2008. No one is likely to research

something which has been settled long ago.

There have been many speculative articles and opinion pieces in support

of the patch test, mostly from Guy Abraham and the iodine group

associated with Optimox, but not one of them ever presented a shred of

credible evidence supporting validity of the test. In the last four

years, they have withdrawn advocacy of this test in favor of another

bogus test, the so-called " loading " test. Have you taken that one?

The main problem with both tests is that they tend to indicate that

everyone that takes one needs to buy iodine from Optimox. So, my

recommendation is that if you give the iodine shills a scintilla of

credibility, just go ahead and take the stuff, preferably from a less

costly supplier. Save yourself the cost of a test that is almost

guaranteed to show you " deficient " in iodine, anyway. Just be cautious

near the threshold of anaphylactoid reactions, about 3 mg, as these can

be dangerous.

Chuck