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Re: Anyone on TRT still having concentration, brain fog trouble / Tachyphylaxis

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I've had a lot of problems with " brain fog " and this has really

messed up my life. I finally got thyroid treatment and this has

helped, although I would say the change has been modest.

The experience of a drug treatment helping for a short time and

then having the positive effect go away is very common. I have

heard that this process has the name " tachyphylaxis " . It seems

like it happens to me with almost every new treatment I have

tried. In particular HCG seemed like a miracle drug and gave

me the libido of a teenager, for about a week.. Recently, I have

been using tamoxifen (inhibits effect of E2). This made me feel

really good for the first few weeks, but now I am not noticing the

effect anymore. Maybe some scientists know why it is that the

human body seems to adjust to eliminate the effect of new

medications but if so, I haven't heard what they have discovered.

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I totally agree with this... I have experienced the same thing with

all meds in regards to libido etc. Hcg did the same thing for me..

felt incredible for 4 weeks and then its slowly adjusted back.. the

body is just amazing how it will always adapt. We are tampering with

something that is alot more complicated than we fully understand at

this time..

Bobby.. I had the same problem as you in regards to the

testosterone, lots of fog and sexual dysfunction at 250 mgs a week

after a period of time..mine took longer to set in as I was taking

Sustanon, which I think is a superior blend of testosterone esters

rather than just the one, cypionate. My Estrogen levels were very

high like yours.

What has helped me, was stopping the testosterone for a period of 2

months and then slowly starting it again at a much lower dose... my

brain fog has gone and my sex dysfunction has improved incredibly.

I tried arimidex and felt awful on it after just a few days... it

made me feel extremely foggy, so I stopped it.

While I stopped the testosterone I took just HcG... so I still had

some testosterone in my system. I still take some HcG but just a

very small amount once or twice a week to maintain some testicular

function.

Its obvious to me that you can have the fog at either end of

estrogen extremes.

250mgs is alot of testosterone per week... I like the benifits of

taking that much for the gym... as im a gym instructor, but it

caused too many other problems.. it gave me a level of 1350ng/dl...

too high!!

I have experiemented a little recently with 250mgs again.. and sure

enough after 1 day following the injection, my problems come back

for a few days.. then It all starts to improve as the e2 must get

metabolized.

> I've had a lot of problems with " brain fog " and this has really

> messed up my life. I finally got thyroid treatment and this has

> helped, although I would say the change has been modest.

>

> The experience of a drug treatment helping for a short time and

> then having the positive effect go away is very common. I have

> heard that this process has the name " tachyphylaxis " . It seems

> like it happens to me with almost every new treatment I have

> tried. In particular HCG seemed like a miracle drug and gave

> me the libido of a teenager, for about a week.. Recently, I have

> been using tamoxifen (inhibits effect of E2). This made me feel

> really good for the first few weeks, but now I am not noticing the

> effect anymore. Maybe some scientists know why it is that the

> human body seems to adjust to eliminate the effect of new

> medications but if so, I haven't heard what they have discovered.

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