Guest guest Posted October 10, 2004 Report Share Posted October 10, 2004 Hi Retro, I remember awhile back you asked if I had any sources which said Arimidex lowered IGF-1. At the time, I could only remember what people on the group have stated, but after re-reading the link Phil posted it does mention it. Arimidex lowered IGF-1 by 18% in this study posted by Phil. http://www.medibolics.com/ArimidexBoostsTestosterone.htm -------------------------------------------------------- However, E2 concentrations decreased 48% (P = 0.006), with no significant change in mean and peak GH concentrations, but with an 18% decrease in plasma insulin-like growth factor I concentrations. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2004 Report Share Posted October 10, 2004 On Mon, 11 Oct 2004 00:23:14 -0000, you wrote: > >Hi Retro, > >I remember awhile back you asked if I had any sources which said >Arimidex lowered IGF-1. At the time, I could only remember what >people on the group have stated, but after re-reading the link Phil >posted it does mention it. > >Arimidex lowered IGF-1 by 18% in this study posted by Phil. > >http://www.medibolics.com/ArimidexBoostsTestosterone.htm >-------------------------------------------------------- >However, E2 concentrations decreased 48% (P = 0.006), with >no significant change in mean and peak GH concentrations, but with an >18% decrease in plasma insulin-like growth factor I concentrations. Thanks! I'll have to think about what this means for a time. - - - - Just another albino black sheep Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2004 Report Share Posted October 11, 2004 The study is interesting but its implications but it is not clear that there are any real implications. First of all, it was based on a study of 16 year olds. 16 year olds are cranking out T bigtime and there are major gains to be had by stopping its conversion to T. For older men, there are gains in T from using arimidex but not as substantial. Second, usually we are concerned about IGF-1 as a measure of GH, since GH is harder to measure. However, it is th GH that really matters. In this case they measured both the GH and the IGF and there was no change in the GH so it is not clear to me why we care about the IGF. Third, tests for IGF come back all over the place and notoriously vary widely from lab to lab and even with two tests sent to the same lab. So there could be an 18% difference one time and then something different the next. On top of that, they seem to be testing a population of 16 year olds that already have some growth problems so for a number of reasons I cannot immediately translate results over to older men. It is good information though and every piece of the picture fits somewhere I think. Winter >From: retrogrouch@... >Reply- > >Subject: Re: Arimidex decreases IGF-1 >Date: Sun, 10 Oct 2004 20:45:21 -0700 > >On Mon, 11 Oct 2004 00:23:14 -0000, you wrote: > > > > >Hi Retro, > > > >I remember awhile back you asked if I had any sources which said > >Arimidex lowered IGF-1. At the time, I could only remember what > >people on the group have stated, but after re-reading the link Phil > >posted it does mention it. > > > >Arimidex lowered IGF-1 by 18% in this study posted by Phil. > > > >http://www.medibolics.com/ArimidexBoostsTestosterone.htm > >-------------------------------------------------------- > >However, E2 concentrations decreased 48% (P = 0.006), with > >no significant change in mean and peak GH concentrations, but with an > >18% decrease in plasma insulin-like growth factor I concentrations. > > >Thanks! I'll have to think about what this means for a time. > >- - - - >Just another albino black sheep > Quote Link to comment Share on other sites More sharing options...
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