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RE: Free Androgen Index

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Hi Tezac

The Free Androgen Index is a calculation based on your Total

Testosterone reading divided by your Serum testosterone Reading

multiplied by 100.

It can be misleading. Can you get the Serum testosterone number and the

SHBG number and post them please

Nick

>

> Hi this is my first time on here and already i'm confused.

> Does anybody know what is meant by free androgen index and what it

> means. example i was given a number of: 8.30am blood test 65, 12.30

> blood test 51, 16.30 blood test 69.7 the ref.range is 22 - 65 UK

> readings.

> Any help please

> thanks in advance

> tezack

>

>

>

>

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  • 2 years later...
Guest guest

Here is a link that will do this for you.

http://www.issam.ch/freetesto.htm

Phil

williamb11 <no_reply > wrote:

I see from some research that you can get a " rough " estimate of free

test by taking total T (ng/dl) multiply by 3.47 and dividing by SHBG

(nmol/L). This gives you a Free Anrogen Index, which should be

between 17 and 173 - obviously higher the better.

What do folks think about this calculation and its usefulness if you

don't have free test. read in labs yet???

Thanks,

Bill

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Rich,

I had a hard time understanding the link formula that Phil sent too!

The FAI equation that I posted is from the Mass General Hopsital in

Boston, per my blood work.

Using it, you would have an estimated free T of 42.1, on a scale of

17-173.

I think this is pretty cool. Your lab says free T is 43.7 which is

not too off from estimate 42.1. Still in 25% of the top, though. I

am at 48.

I think it is a " back of the envelope way " to save money from always

running a free T test

Blessings,

Bill

> >

> > I see from some research that you can get a " rough " estimate of

> free

> > test by taking total T (ng/dl) multiply by 3.47 and dividing by

> SHBG

> > (nmol/L). This gives you a Free Anrogen Index, which should be

> > between 17 and 173 - obviously higher the better.

> >

> > What do folks think about this calculation and its usefulness if

> you

> > don't have free test. read in labs yet???

> >

> > Thanks,

> > Bill

> >

>

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Bill,

The FAI (Free Androgen Index) is a VERY poor guide to free

testosterone, was created for use in women and should NOT be used to

determine the free testosterone level in men as it is diagnostically

unsound.

So say many endocrine sources.

I have had an FAI and then a day later an actual free test.

Results

The FAI stated 151 range 14-97- it was saying that my free

testosterone was much higher than the top of the normal range.

Whereas the actual results showed this;

Free Testosteroen 20.8pg/ml range 8.8-27- so I was actually well

within the normal range and in fact not even at the top of it.

So not only do many endocirne sources state that the FAI is an unsound

method of ascertaining a free testosterone estimate but in actual fact

I have seen in practice just how unsound it actually is.

The FAI does not take into account estradiol whatsoever something that

can have a great influence on free testosterone levels, also it is

only a theoritical estimate and a bad one at that.

STEER CLEAR OF IT!!!!!

Chris

>

> I see from some research that you can get a " rough " estimate of free

> test by taking total T (ng/dl) multiply by 3.47 and dividing by SHBG

> (nmol/L). This gives you a Free Anrogen Index, which should be

> between 17 and 173 - obviously higher the better.

>

> What do folks think about this calculation and its usefulness if you

> don't have free test. read in labs yet???

>

> Thanks,

> Bill

>

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Guest guest

Hey

I appreciate the wisdom and your clearing this up for me. Always

willing to learn and stand corrected!

Bill

> >

> > I see from some research that you can get a " rough " estimate of

free

> > test by taking total T (ng/dl) multiply by 3.47 and dividing by

SHBG

> > (nmol/L). This gives you a Free Anrogen Index, which should be

> > between 17 and 173 - obviously higher the better.

> >

> > What do folks think about this calculation and its usefulness if

you

> > don't have free test. read in labs yet???

> >

> > Thanks,

> > Bill

> >

>

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Guest guest

That first range that starts at 250 is wrong. A couple of the labs

seem to think that if your at the average Testosterone level of a 120

year old man your " ok " The problem is that most MDs and such look at

the results and think " Hormones ok he must be mentaly depressed " and

then you go on some SSRI and your don't CARE that you've got no sex

drive, your energy is shot to hell, your memory is fried and so on.

Can SOMEONE talk to Quest Labs or whoever and suggest they get with

the program?

> >

> > I see from some research that you can get a " rough " estimate of

> free

> > test by taking total T (ng/dl) multiply by 3.47 and dividing by

> SHBG

> > (nmol/L). This gives you a Free Anrogen Index, which should be

> > between 17 and 173 - obviously higher the better.

> >

> > What do folks think about this calculation and its usefulness if

> you

> > don't have free test. read in labs yet???

> >

> > Thanks,

> > Bill

> >

>

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Guest guest

The Free Androgen index has been proved to be unreliable in men.

It depends on SHBG, which can vary man to man.

The lower the SHBG against Testosterone, the greater the FAI number, which

by definition, as far as the ignorant are concerned, would indicate T levels

are ok.

Recent studies have found the combo of low Testosterone and low SHBG to lead

to Metabolic Syndrome and possibly Type 2 Diabetes.

Hope it helps,

Nick

> Re: Free Androgen Index

>

> That first range that starts at 250 is wrong. A couple of

> the labs seem to think that if your at the average

> Testosterone level of a 120 year old man your " ok " The

> problem is that most MDs and such look at the results and

> think " Hormones ok he must be mentaly depressed " and then you

> go on some SSRI and your don't CARE that you've got no sex

> drive, your energy is shot to hell, your memory is fried and so on.

>

> Can SOMEONE talk to Quest Labs or whoever and suggest they

> get with the program?

>

> > >

> > > I see from some research that you can get a " rough " estimate of

> > free

> > > test by taking total T (ng/dl) multiply by 3.47 and dividing by

> > SHBG

> > > (nmol/L). This gives you a Free Anrogen Index, which should be

> > > between 17 and 173 - obviously higher the better.

> > >

> > > What do folks think about this calculation and its usefulness if

> > you

> > > don't have free test. read in labs yet???

> > >

> > > Thanks,

> > > Bill

> > >

> >

>

>

>

>

>

>

>

>

>

>

>

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Guest guest

Hi Nick,

According to the Endocrine Society of Australia it is unsound (which

is funny as they are an unsound organisation themselves:)

But for the US and Austalia to basically ignore the FAI in favour of

other methodologies tells me something.

What tells me that it is wrong is also the fact that I have had a

free test and had testosterone calculated by the FAI at the same

time and the free test showed that my T levels were mid range on one

and a half packets of testogel and the FAI indicated I was almost

double the free T range.

You are right about the FAI equation in that its results are almost

entirely based upon SHBG levels- certainly it is only an estimate or

as I prefer to call it a gestimate based on nothing more than the

supposed average man (having been created for use in women:).

It doesn't take the individual into account in any way, their

genetics or their other hormones that exert significant influences

on free T.

Total Testosterone / SHBG * 100

So if an individual had 5nmol/l / 6nmol/l * 100 = unit less 83 FAI

Which would basically mean that a man with 5nmol/l would be deemed

to have enough testosterone.

In fact theoretically

If an individual had 2nmol/l / 3nmol/l * 100 = 66 FAI which would

seem ok. HELLO :)

This would suggest that a testosterone level of 57.6ng/dl would be

ok!!!!!!!! HELLO :)

So the FAI becomes truly absurd when dealing with men with low SHBG

levels and is a VERY poor indicator of free testosterone in such men.

This calculation is so blatantly poor and redundant that doctors

should stop using it;

Immediately!

> > > >

> > > > I see from some research that you can get a " rough " estimate

of

> > > free

> > > > test by taking total T (ng/dl) multiply by 3.47 and dividing

by

> > > SHBG

> > > > (nmol/L). This gives you a Free Anrogen Index, which should

be

> > > > between 17 and 173 - obviously higher the better.

> > > >

> > > > What do folks think about this calculation and its

usefulness if

> > > you

> > > > don't have free test. read in labs yet???

> > > >

> > > > Thanks,

> > > > Bill

> > > >

> > >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

> >

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Guest guest

Did you guys read the Explanation and Examples that the link.

http://www.issam.ch/freetesto.htm

I never tried this but the guys that were using it said it worked.

Phil

james186282 <pillow@...> wrote:

That first range that starts at 250 is wrong. A couple of the labs

seem to think that if your at the average Testosterone level of a 120

year old man your " ok " The problem is that most MDs and such look at

the results and think " Hormones ok he must be mentaly depressed " and

then you go on some SSRI and your don't CARE that you've got no sex

drive, your energy is shot to hell, your memory is fried and so on.

Can SOMEONE talk to Quest Labs or whoever and suggest they get with

the program?

> >

> > I see from some research that you can get a " rough " estimate of

> free

> > test by taking total T (ng/dl) multiply by 3.47 and dividing by

> SHBG

> > (nmol/L). This gives you a Free Anrogen Index, which should be

> > between 17 and 173 - obviously higher the better.

> >

> > What do folks think about this calculation and its usefulness if

> you

> > don't have free test. read in labs yet???

> >

> > Thanks,

> > Bill

> >

>

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Guest guest

The problem is your doctor, not the lab. It's the doctor who

interprets those numbers. The lab gives a reference range. It's not

a hard and fast rule. If your doc is taking it as such have a talk

with him. If he won't see the light get another doctor. Don't act

like a victim, take control of your life.

>

> That first range that starts at 250 is wrong. A couple of the labs

> seem to think that if your at the average Testosterone level of a 120

> year old man your " ok " The problem is that most MDs and such look at

> the results and think " Hormones ok he must be mentaly depressed " and

> then you go on some SSRI and your don't CARE that you've got no sex

> drive, your energy is shot to hell, your memory is fried and so on.

>

> Can SOMEONE talk to Quest Labs or whoever and suggest they get with

> the program?

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Guest guest

You have an excellent point. The labs my Doctor used had this same

reading but he ACCE guilines are at (uhh can't remember exactlty) 340?

Whatever. She told me that " symptoms " were just as important in a

correct diagnosis. And even tho the lab said " Normal " she prescribed

Androgel and upped the dose until I was nearer the middle of the range

and started feeling right.

My point is that some doctors without a lot of experience with

hormones will say " Lab check is normal what else can it be!? Maybe

depression since thats not testable in a lab "

<SIGH>

> >

> > That first range that starts at 250 is wrong. A couple of the labs

> > seem to think that if your at the average Testosterone level of a 120

> > year old man your " ok " The problem is that most MDs and such look at

> > the results and think " Hormones ok he must be mentaly depressed " and

> > then you go on some SSRI and your don't CARE that you've got no sex

> > drive, your energy is shot to hell, your memory is fried and so on.

> >

> > Can SOMEONE talk to Quest Labs or whoever and suggest they get with

> > the program?

>

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Guest guest

a good rule of thumb is to get your Total and Free T in the upper 1/3 of

your labs range and work from there some need to go to the top of the range.

And some do dam good just in the upper 1/3. I feel if one knew what his levels

were when he was 20 say they were 600 on meds you my need to be higher like 700

to feel the same to much of the med is lost do to stress and illness. Read this

link it is all in here a lot to read but worth it.

http://www.lef.org/protocols/prtcls-txt/t-prtcl-130.html

Phil

james186282 <pillow@...> wrote:

You have an excellent point. The labs my Doctor used had this same

reading but he ACCE guilines are at (uhh can't remember exactlty) 340?

Whatever. She told me that " symptoms " were just as important in a

correct diagnosis. And even tho the lab said " Normal " she prescribed

Androgel and upped the dose until I was nearer the middle of the range

and started feeling right.

My point is that some doctors without a lot of experience with

hormones will say " Lab check is normal what else can it be!? Maybe

depression since thats not testable in a lab "

> >

> > That first range that starts at 250 is wrong. A couple of the labs

> > seem to think that if your at the average Testosterone level of a 120

> > year old man your " ok " The problem is that most MDs and such look at

> > the results and think " Hormones ok he must be mentaly depressed " and

> > then you go on some SSRI and your don't CARE that you've got no sex

> > drive, your energy is shot to hell, your memory is fried and so on.

> >

> > Can SOMEONE talk to Quest Labs or whoever and suggest they get with

> > the program?

>

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