Guest guest Posted August 11, 2004 Report Share Posted August 11, 2004 I know Dr. recommends .25mg EOD to start. > I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 times > a week, and my E2 crashed too low to 8. > > I went off it for a month and was back at 43. > > Anyway as I'm cautiously starting back in I went to find out what I > could about dosing. Of course all the literature is about women's > doses. > > But here's what I get from the prescribing pamphlet. > > " Effect on Estradiol: Mean serum concentrations of estradiol were > evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and 10 mg > of ARIMIDEX in postmenopausal women with advanced breast cancer. > Clinically significant suppression of serum estradiol was seen with > all doses. Doses of 1 mg and higher resulted in suppression of mean > serum concentrations of estradiol to the lower limit of detection > (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced > estradiol by approximately 70% within 24 hours and by approximately > 80% after 14 days of daily dosing. Suppression of serum estradiol was > maintained for up to 6 days after cessation of daily dosing > with ARIMIDEX 1 mg. > > - - - - > Just another albino black sheep Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2004 Report Share Posted August 12, 2004 Wow.. so just after 24 hours 70% has been reduced.... thats powerfull stuff!!! > I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 times > a week, and my E2 crashed too low to 8. > > I went off it for a month and was back at 43. > > Anyway as I'm cautiously starting back in I went to find out what I > could about dosing. Of course all the literature is about women's > doses. > > But here's what I get from the prescribing pamphlet. > > " Effect on Estradiol: Mean serum concentrations of estradiol were > evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and 10 mg > of ARIMIDEX in postmenopausal women with advanced breast cancer. > Clinically significant suppression of serum estradiol was seen with > all doses. Doses of 1 mg and higher resulted in suppression of mean > serum concentrations of estradiol to the lower limit of detection > (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced > estradiol by approximately 70% within 24 hours and by approximately > 80% after 14 days of daily dosing. Suppression of serum estradiol was > maintained for up to 6 days after cessation of daily dosing > with ARIMIDEX 1 mg. > > - - - - > Just another albino black sheep Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2004 Report Share Posted August 12, 2004 On Thu, 12 Aug 2004 07:34:14 -0000, you wrote: >Wow.. so just after 24 hours 70% has been reduced.... thats >powerfull stuff!!! Yeah. I find this puzzling as it doesn't seem to comport with peoples experience here. I think perhaps the much much higher levels in women drop quicker. But its definitely worth thinking about when trying to figure out how much and how often to take it. > >> I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 >times >> a week, and my E2 crashed too low to 8. >> >> I went off it for a month and was back at 43. >> >> Anyway as I'm cautiously starting back in I went to find out what I >> could about dosing. Of course all the literature is about women's >> doses. >> >> But here's what I get from the prescribing pamphlet. >> >> " Effect on Estradiol: Mean serum concentrations of estradiol were >> evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and >10 mg >> of ARIMIDEX in postmenopausal women with advanced breast cancer. >> Clinically significant suppression of serum estradiol was seen with >> all doses. Doses of 1 mg and higher resulted in suppression of mean >> serum concentrations of estradiol to the lower limit of detection >> (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced >> estradiol by approximately 70% within 24 hours and by approximately >> 80% after 14 days of daily dosing. Suppression of serum estradiol >was >> maintained for up to 6 days after cessation of daily dosing >> with ARIMIDEX 1 mg. >> >> - - - - >> Just another albino black sheep > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2004 Report Share Posted August 12, 2004 On Thu, 12 Aug 2004 09:01:55 -0700 (PDT), you wrote: >HI Reto I am doing a half a pill .5 mgs. every 10 days now that my levels are back up I had a half a pill on Tue. and it made me feel even better. So doing it every 10 days I am finding that it is lasting a long time. I hope this works for me I did notice my nipples were acting up just before taking it and after I am ok. How are you taking yours now. I was at 43 two days ago, so I took 1 mg, then .5 the next two days with the thought of getting it down somewhat quickly. (I just got a new job and with this high level I'm very very fuzzy. And after that I'm going to .5mg a week for a few weeks and then push for a test. - - - - Just another albino black sheep Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2004 Report Share Posted August 12, 2004 Hi all (and Phil), I started on Arimidex the other day and guess what? My first dose was a half of a 1mg pill. After 24hours, I had my first noctournal erection in years! Not only was I able to get it up to spnak it, but it felt good, too. I'm 41, normal high total T, low normal free t, way below normal free T% to total T and high estrogen. I think I finally found the problem and a cure for the problem with the low free t and high estidiol. Reducing my estridiol has returned sensitivity, drive and erections. WOW! This is big..... no pun intended! Today, I talked to a pharmocologist about arimidex. I mentioned that I know a few people who cut the pills and take it 1x or 2x per week. The Pharmo feels that we'll have a difficult time getting stable on that kind of time between doages because of the half life of arimidex. He likend it to a diebetic taking insulin twice a week. What he is suggesting is to take the medication daily and the way to do that is to have the pills ground up, dosages weighed, filler sunstance added and then the mixture put into gelatin capsules for a predetermined daily dosage. He told me that there are places tha will do this but I'll have to be the one to find where. Thought some of you arimidex users might be interested in this. Any thoughts? Chris > I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 times > a week, and my E2 crashed too low to 8. > > I went off it for a month and was back at 43. > > Anyway as I'm cautiously starting back in I went to find out what I > could about dosing. Of course all the literature is about women's > doses. > > But here's what I get from the prescribing pamphlet. > > " Effect on Estradiol: Mean serum concentrations of estradiol were > evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and 10 mg > of ARIMIDEX in postmenopausal women with advanced breast cancer. > Clinically significant suppression of serum estradiol was seen with > all doses. Doses of 1 mg and higher resulted in suppression of mean > serum concentrations of estradiol to the lower limit of detection > (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced > estradiol by approximately 70% within 24 hours and by approximately > 80% after 14 days of daily dosing. Suppression of serum estradiol was > maintained for up to 6 days after cessation of daily dosing > with ARIMIDEX 1 mg. > > - - - - > Just another albino black sheep > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2004 Report Share Posted August 12, 2004 Congrats on your improvement! I would try a compounding pharmacy - I think they do stuff like what he is talking about. Mark Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2004 Report Share Posted August 12, 2004 I curious what your E2 levels prior to taking arimidex. What are your T levels are you on any form of TRT or just on arimidex, Im interested cuz my E2 is high as well. Thanks! > > I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 > times > > a week, and my E2 crashed too low to 8. > > > > I went off it for a month and was back at 43. > > > > Anyway as I'm cautiously starting back in I went to find out what I > > could about dosing. Of course all the literature is about women's > > doses. > > > > But here's what I get from the prescribing pamphlet. > > > > " Effect on Estradiol: Mean serum concentrations of estradiol were > > evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and > 10 mg > > of ARIMIDEX in postmenopausal women with advanced breast cancer. > > Clinically significant suppression of serum estradiol was seen with > > all doses. Doses of 1 mg and higher resulted in suppression of mean > > serum concentrations of estradiol to the lower limit of detection > > (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced > > estradiol by approximately 70% within 24 hours and by approximately > > 80% after 14 days of daily dosing. Suppression of serum estradiol > was > > maintained for up to 6 days after cessation of daily dosing > > with ARIMIDEX 1 mg. > > > > - - - - > > Just another albino black sheep > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2004 Report Share Posted August 13, 2004 > Hi all (and Phil), > > I started on Arimidex the other day and guess what? My first dose > was a half of a 1mg pill. After 24hours, I had my first noctournal > erection in years! Not only was I able to get it up to spnak it, but > it felt good, too. I'm 41, normal high total T, low normal free t, > way below normal free T% to total T and high estrogen. I think I > finally found the problem and a cure for the problem with the low > free t and high estidiol. Reducing my estridiol has returned > sensitivity, drive and erections. WOW! This is big..... no pun > intended! > > Today, I talked to a pharmocologist about arimidex. I mentioned that > I know a few people who cut the pills and take it 1x or 2x per week. > The Pharmo feels that we'll have a difficult time getting stable on > that kind of time between doages because of the half life of > arimidex. He likend it to a diebetic taking insulin twice a week. > What he is suggesting is to take the medication daily and the way to > do that is to have the pills ground up, dosages weighed, filler > sunstance added and then the mixture put into gelatin capsules for a > predetermined daily dosage. He told me that there are places tha > will do this but I'll have to be the one to find where. > > Thought some of you arimidex users might be interested in this. Any > thoughts? -------------------------------------- My compounding pharmacy told me the same thing, that I should take a 1/4 of an arimidex every day for same reason. I did and it drove my E2 so low I could not get erect or orgasm or nothing. It took three weeks for things to come back. Now I take 1/2 an arimidex every four days or so. norton Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2004 Report Share Posted August 13, 2004 Hi Great news! That confirms my opinion that Arimidex is effective and fast. It works so well that it can quickly become " too much of a good thing " . I advise taking the lowest dose that provides good results. Especially when you got results that quickly, with a single 0.5mg dose. My understanding is that taking Arimidex reduces E2 quickly, but stopping it raises E2 slowly. (I'll know more about my personal experience when I get lab results Monday.) That might mean that effects last longer than half life, and stable E2 levels can be achieved with doses far apart. That's my SWAG. Opinions anyone? Bruce > > I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 > times > > a week, and my E2 crashed too low to 8. > > > > I went off it for a month and was back at 43. > > > > Anyway as I'm cautiously starting back in I went to find out what I > > could about dosing. Of course all the literature is about women's > > doses. > > > > But here's what I get from the prescribing pamphlet. > > > > " Effect on Estradiol: Mean serum concentrations of estradiol were > > evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and > 10 mg > > of ARIMIDEX in postmenopausal women with advanced breast cancer. > > Clinically significant suppression of serum estradiol was seen with > > all doses. Doses of 1 mg and higher resulted in suppression of mean > > serum concentrations of estradiol to the lower limit of detection > > (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced > > estradiol by approximately 70% within 24 hours and by approximately > > 80% after 14 days of daily dosing. Suppression of serum estradiol > was > > maintained for up to 6 days after cessation of daily dosing > > with ARIMIDEX 1 mg. > > > > - - - - > > Just another albino black sheep > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2004 Report Share Posted August 13, 2004 I bought a jeweler's scale for $200 that allows me to fine tune my dosage to 2 mg (0.002 g). See: http://balanc.temp.veriohosting.com/paypal/diamond.html Re: Arimidex dosing > Hi all (and Phil), > > I started on Arimidex the other day and guess what? My first dose > was a half of a 1mg pill. After 24hours, I had my first noctournal > erection in years! Not only was I able to get it up to spnak it, but > it felt good, too. I'm 41, normal high total T, low normal free t, > way below normal free T% to total T and high estrogen. I think I > finally found the problem and a cure for the problem with the low > free t and high estidiol. Reducing my estridiol has returned > sensitivity, drive and erections. WOW! This is big..... no pun > intended! > > Today, I talked to a pharmocologist about arimidex. I mentioned that > I know a few people who cut the pills and take it 1x or 2x per week. > The Pharmo feels that we'll have a difficult time getting stable on > that kind of time between doages because of the half life of > arimidex. He likend it to a diebetic taking insulin twice a week. > What he is suggesting is to take the medication daily and the way to > do that is to have the pills ground up, dosages weighed, filler > sunstance added and then the mixture put into gelatin capsules for a > predetermined daily dosage. He told me that there are places tha > will do this but I'll have to be the one to find where. > > Thought some of you arimidex users might be interested in this. Any > thoughts? > > Chris > > > > I had high E2 (46) and went on arimidex finally at .5 mg 3 to 4 > times > > a week, and my E2 crashed too low to 8. > > > > I went off it for a month and was back at 43. > > > > Anyway as I'm cautiously starting back in I went to find out what I > > could about dosing. Of course all the literature is about women's > > doses. > > > > But here's what I get from the prescribing pamphlet. > > > > " Effect on Estradiol: Mean serum concentrations of estradiol were > > evaluated in multiple daily dosing trials with 0.5, 1, 3, 5, and > 10 mg > > of ARIMIDEX in postmenopausal women with advanced breast cancer. > > Clinically significant suppression of serum estradiol was seen with > > all doses. Doses of 1 mg and higher resulted in suppression of mean > > serum concentrations of estradiol to the lower limit of detection > > (3.7 pmol/L). The recommended daily dose, ARIMIDEX 1 mg, reduced > > estradiol by approximately 70% within 24 hours and by approximately > > 80% after 14 days of daily dosing. Suppression of serum estradiol > was > > maintained for up to 6 days after cessation of daily dosing > > with ARIMIDEX 1 mg. > > > > - - - - > > Just another albino black sheep > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 4, 2009 Report Share Posted May 4, 2009 > > This was posted by someone else with no responses. I was curious too. > > Can someone who knows please tell me how to dose AI's. Arimidex in this particular case. I was kinda leaning toward it might be a drug that is dosed based on body weight and not the amount of testosterone we are dealing with. I know that the maximum suppression is about 80% (i think). SO lets use that figure. Say you want maximum effectiveness scenerio.. Anyone Please...? > > OK, bad choice of words for thread title. Manufacturer states that 1mg / day will achieve about 75% Estrogen reduction within a day. They then go on to state that you can get up to a full 80% reduction within 2 weeks or same dosing. > > I would really like to see some curves with regard to estrogen suppression as it relates to different T doses.? Could it be that you can not achieve enough E suppression with taking large amounts of T? I mean to say. Percentages are percentages, Right??? BUt a 20% effective reduction of E based on 1000 mgs test /week is still gonna leave you way high right?? So are we dealing with effective proprotions, or amounts. Obivously to be " hormonally correct " , everything must be in the correct relation to each other (Estradiol counters androgens, etc..) BUT is too much E2 simply too much E2. AND where does this supply of conversion enzymes come from and what affects the amount of those available.? Is dosing relavant to body weight or the amount hormones we are working with? FURTHER, is this the best drug to try to tweek around with? Meaning, does it have a tendency to just want to do its thing and shut down 80% of all e production even in small doses. Or is it easy to obtain the desired partial response. What I am getting at is that perhaps letro could be the better drug to try to get a 25 or 50% response from???? > Hi, In my personal experience the Arimidex was the most difficult thing to get right,took me over a year and it still varies now and then. I am about 270 and I ended up using 3 drops of the liquid version every other day along with 200mg DIM , one in the morning, one at night. I was always curious if the DIM actually did anything but for me it works in support of the arimidex. I ran out of DIM a couple weeks back and could definitely notice that things weren't right without it. I can't answer the technical questions, just adding my 2 cents what seems to be working for me... Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 5, 2009 Report Share Posted May 5, 2009 1000 mg of T is an awful lot. The normal dose would be 100 mg a week, so you are hitting it very hard. Are you doing this on a short term " cycle " or continuing it for some longer time? In any case that dosage puts you in the category of a home science experiment. The aromatase enzyme resides mostly in adipose(fat)tissue so the more of that you have the more likely you are to have conversion of T to E2. The 1 mg / day dosage is for women with cancer. A typical effective dose for a man would be 1/4 mg every other day. I've read scientific papers that indicate that increasing the dose of Arimidex beyond a certain point doesn't seem to reduce E2 any more. i.e. 1/2 mg is as effective as 1 mg. If you are taking 10 X the usual dose of T, then there certainly will be plenty of " fuel " to make more estradiol. I would think that the T:E2 ratio is the important thing, and if you have very high levels of T, you would want a fairly high level of E2, to match. All this begs the question.... What are you trying to accomplish? > > I would really like to see some curves with regard to estrogen suppression as it relates to different T doses.? Could it be that you can not achieve enough E suppression with taking large amounts of T? I mean to say. Percentages are percentages, Right??? BUt a 20% effective reduction of E based on 1000 mgs test /week is still gonna leave you way high right?? So are we dealing with effective proprotions, or amounts. Obivously to be " hormonally correct " , everything must be in the correct relation to each other (Estradiol counters androgens, etc..) BUT is too much E2 simply too much E2. AND where does this supply of conversion enzymes come from and what affects the amount of those available.? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 5, 2009 Report Share Posted May 5, 2009 > > I would really like to see some curves with regard to > > estrogen suppression as it relates to different T doses.? > > Could it be that you can not achieve enough E suppression > > with taking large amounts of T? I mean to say. Percentages > > are percentages, Right??? BUt a 20% effective reduction of E > > based on 1000 mgs test /week is still gonna leave you way > > high right?? So are we dealing with effective proprotions, > > or amounts. Hi, ok... if you're doing a gram a week of test you're in the BB world. and really... you should consider less Test and stacking with something else... deca or primo maybe... fewer sides... but this really isn't the group for that. IP China does 1/4mg tabs for example for daily use... and we both know that IP caters to the BB market. there is evidence that more than that really doesn't help any more than 1/2 or 1mg... though I've heard of NYC " leading edge " practitioners prescribing 1mg of arimidex a day with NO supplemental test. really though... a gram of test a week is to much. (unless you just messed up your math... 1000mg would be 5 full CC shots of the standard 200mg/ml testosterone depot) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 Some men don't need to control E2 others have a little to big problem with it. There is no set rule on how to take some do very good on a low dose others need a lot. Yes the more T you use that you don't need the more E2 will go up same with HCG use. Co-Moderator Phil > From: Thornton <brianee93@...> > Subject: Re: Re: Arimidex Dosing > > Date: Tuesday, May 5, 2009, 3:58 PM > I just read this on a forum and copied it over. I was just > curious if your Arimidex amounts need to increase with the > amount of Test. or if the amount that converts is pretty > consistent due to limited aromatase? > > > > > ________________________________ > From: Randy Hoops <Randy@...> > > Sent: Tuesday, May 5, 2009 8:45:58 AM > Subject: Re: Arimidex Dosing > > > > > > 1000 mg of T is an awful lot. The normal dose would be 100 > mg a week, so you are hitting it very hard. Are you doing > this on a short term " cycle " or continuing it for > some longer time? > > In any case that dosage puts you in the category of a home > science experiment. > > The aromatase enzyme resides mostly in adipose(fat) tissue > so the more of that you have the more likely you are to have > conversion of T to E2. > > The 1 mg / day dosage is for women with cancer. A typical > effective dose for a man would be 1/4 mg every other day. > > I've read scientific papers that indicate that > increasing the dose of Arimidex beyond a certain point > doesn't seem to reduce E2 any more. i.e. 1/2 mg is as > effective as 1 mg. > > If you are taking 10 X the usual dose of T, then there > certainly will be plenty of " fuel " to make more > estradiol. > > I would think that the T:E2 ratio is the important thing, > and if you have very high levels of T, you would want a > fairly high level of E2, to match. > > All this begs the question.... What are you trying to > accomplish? > > > > > > I would really like to see some curves with regard to > estrogen suppression as it relates to different T doses.? > Could it be that you can not achieve enough E suppression > with taking large amounts of T? I mean to say. Percentages > are percentages, Right??? BUt a 20% effective reduction of E > based on 1000 mgs test /week is still gonna leave you way > high right?? So are we dealing with effective proprotions, > or amounts. Obivously to be " hormonally correct " , > everything must be in the correct relation to each other > (Estradiol counters androgens, etc..) BUT is too much E2 > simply too much E2. AND where does this supply of conversion > enzymes come from and what affects the amount of those > available.? > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 Dr. has said that progesterone enhances estrogens effects. He also said that progesterone causes gyno. I asked him what levels of progesterone would cause this problem, and he said he was not sure. The important thing is to keep progesterone within the normal range. Ultimately, it is high progesterone that is the problem, and not " normal " progesterone. Another thing is that HCG causes an increase in estrogen and progesterone simultaneously, as well as an increase in aromatase. Perhaps it is this double action that is the problem, especially with high doses of HCG. Dr. Philip , author of the excellent book " The Life Extension Revolution " , supplements his patients with pregnenolone in order to increase progesterone, and has no problem taking progesterone to 2.5 times the normal range. Co-Moderator Phil > From: d00fu524 <calvin1564@...> > Subject: Re: Arimidex Dosing > > Date: Tuesday, May 5, 2009, 6:57 PM > > > > > > > > > This was posted by someone else with no > responses. I was curious too. > > > > > > > > Can someone who knows please tell me how to > dose AI's. Arimidex in this particular case. I was kinda > leaning toward it might be a drug that is dosed based on > body weight and not the amount of testosterone we are > dealing with. I know that the maximum suppression is about > 80% (i think). SO lets use that figure. Say you want maximum > effectiveness scenerio.. Anyone Please...? > > > > > > > > OK, bad choice of words for thread title. > Manufacturer states that 1mg / day will achieve about 75% > Estrogen reduction within a day. They then go on to state > that you can get up to a full 80% reduction within 2 weeks > or same dosing. > > > > > > > > I would really like to see some curves with > regard to estrogen suppression as it relates to different T > doses.? Could it be that you can not achieve enough E > suppression with taking large amounts of T? I mean to say. > Percentages are percentages, Right??? BUt a 20% effective > reduction of E based on 1000 mgs test /week is still gonna > leave you way high right?? So are we dealing with effective > proprotions, or amounts. Obivously to be " hormonally > correct " , everything must be in the correct relation to > each other (Estradiol counters androgens, etc..) BUT is too > much E2 simply too much E2. AND where does this supply of > conversion enzymes come from and what affects the amount of > those available.? Is dosing relavant to body weight or the > amount hormones we are working with? FURTHER, is this the > best drug to try to tweek around with? Meaning, does it have > a tendency to just want to do its thing and shut down 80% of > all e production even in small doses. Or is it easy to > obtain the desired partial response. What I am getting at is > that perhaps letro could be the better drug to try to get a > 25 or 50% response from???? > > > > > > > > > > Hi, > > > In my personal experience the Arimidex was the > most difficult thing to get right,took me over a year and > it still varies now and then. I am about 270 and I ended up > using 3 drops of the liquid version every other day along > with 200mg DIM , one in the morning, one at night. I was > always curious if the DIM actually did anything but for me > it works in support of the arimidex. I ran out of DIM a > couple weeks back and could definitely notice that things > weren't right without it. I can't answer the > technical questions, just adding my 2 cents what seems to > be working for me... > > > Jim > > > > > I have found that progesterone works the best. It can > lower E2 levels effectively and consistently. You can ask > your doctor for a prescription for compounded progesterone > cream 6 mg/day rubbed on your leg every night before bed. > Progesterone levels typically are lower than normal because > the testicles will produce less progesterone when less > testostorone is produced. When levels are brought back up to > normal, progesterone is very effective in an indirect way in > reducing the aromatase activity in the body thus reducing > estradiol to normal levels, about 25-35 pg/ml. > > > > Progesterone also just makes you feel good too. > > > > Thanks for sharing, Beth. I'm curious- does taking > progesterone modify the amount of TRT needed, since > progestins ( & perhaps progesterone by extension) can > prevent testosterone from binding to androgen receptors? Or > is this only a concern at a much higher dose of > progesterone? > (http://en.wikipedia.org/wiki/Androgen_receptor) > > ~Xian > > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
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