Re: subcutaneous injections

[Guest guest]

Section 2. Page3 - injecting into the thighs is intramuscular, not

subcutaneous. While it's a very interesting article, it's not specifically

regarding Testosterone.

Personally I find subcutaneous injections quite painful, while intramuscular

injections are relatively pain free.

On other matter's, Androgel became licensed in the UK on the 9th June and

the new patch (worn inside the gum) will be licensed here next summer.

Steph

----- Original Message -----

From: " patrick ritter "

Sent: Sunday, June 15, 2003 5:43 PM

> http://www.cc.nih.gov/ccc/patient_education/pepubs/subq.pdf

[Guest guest]

Here is a cut and paste from this long thread we went over this for a long time.

In this link are 3 Dr.'s posting SWALE aka Dr. , Sunkist and one other.

http://tinyurl.com/3xkr52

===================================================

Re: Injecting testosterone subcutaneously

---------------------------------

STABLE TESTOSTERONE LEVELS ACHIEVED

WITH SUBCUTANEOUS TESTOSTERONE

INJECTIONS

M.B. Greenspan, C.M. Chang

Division of Urology, Department of Surgery, McMaster University,

Hamilton, ON, Canada

Objectives: The preferred technique of androgen replacement

has been intramuscular (IM) testosterone, but wide

variations in testosterone levels are often seen. Subcutaneous

(SC) testosterone injection is a novel approach; however,

its physiological effects are unclear. We therefore investigated

the sustainability of stable testosterone levels using

SC therapy. Patients and methods: Between May and

September 2005, we conducted a small pilot study involving

10 male patients with symptomatic late-onset hypogonadism.

Every patient had been stable on TE 200 mg IM for

41 year. Patients were instructed to self-inject with

testosterone enanthate (TE) 100 mg SC (DELATESTRYL

200 mg/cc, Theramed Corp, Canada) into the anterior

abdomen once weekly. Some patients were down-titrated

to 50 mg based on their total testosterone (T) at 4 weeks.

Informed consent was obtained as SC testosterone administration

is not officially approved by Health Canada. T

levels were measured before and 24 hours after injection

during weeks 1, 2, 3, and 4, and 96 hours after injection

in week 6 and 8. At week 12, PSA, CBC, and T levels

were measured however; the week 12 data are still being

collected. Results: Prior to initiation of SC therapy, T

was 19.14+3.48 nmol/l, hemoglobin 15.8+1.3 g/dl, hematocrit

0.47+0.02, and PSA 1.05+0.65 ng/ml. During

the first 4 weeks, there was a steady increase in

pre-injection T from 19.14+3.48 to 23.89+9.15 nmol/l

(p¼0.1). However, after 8 weeks the post-injection T

(25.77+7.67 nmol/l) remained similar to that of week 1

(27.46+12.91 nmol/l). Patients tolerated this therapy with

no adverse effects. Conclusions: A once-week SC injection

of 50–100 mg of TE appears to achieve sustainable and

stable levels of physiological T. This technique offers

fewer physician visits and the use of smaller quantity of

medication, thus lower costs. However, the long term

clinical and physiological effects of this therapy need further

evaluation.

Norsworthy <norsworthy_david@...> wrote:

Subcutaneous injections are injections administered in abdominal fat.

I read in a posting that Dr. Shippen is following this method for his own

testosterone administration. I suggested this method to my doctor and he said he

will look into it because his belief is that testosterone is supposed to be

intra muscular and not into the stomach fat.

Any sources out there that support subQ injections for administering

testosterone?

---------------------------------

Be a better pen pal. Text or chat with friends inside . See how.

[Guest guest]

SubQ injections work very well. Shippen, with whom I have consulted

over several years, likes them for the smooth levels of serum T they

maintain as well as the fact that by injecting smaller amounts at one

time the possibility of excessive E2 is greatly diminished. I am

currently experimenting with dosage as I got an abnormally high reading

on the last test, but right now am using .2 cc of depo T (200mg/cc)

twice a week, so .4 x 200 mg = 80 mg T per week. I use a 25 guage

needle by pinching my abdominal skin and injecting at a 45º angle. Also

do 250 IU of HCG x2/week in between T shots.

in SF