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DMSA Oral Chelation Schedule - Which is better 3/4 or 3/11?

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We've just started chelating our son with oral DMSA. He is 3.9 yrs

old and 33 lbs. The first week, we did 8mg every 4 hours for 3 days

and had 4 days off. But the second day into the second week of

chelation, he was kind of whiny and seemed uncomfortable so we

stopped.

Now, I want to start again, and I am going to reduce the dose to 5 mg

per every 4 hours. Since the dose is so low, I am thinking of taking

4 days off again.

My question is whether 4 days off or 11 days off is " better " . I

understand it depends on the child's tolerance, but my son is non

verbal, and has weird behaviors, so it's hard to tell if he is

experiencing discomfort.

If we do a 3 on 4 off schedule, would the chelation be " faster " in

the sense that he would respond quicker, or is 3 on 11 off better to

let his body rest a bit. However, I'm concerned that with 11 days

off, the metals will get redistributed and cause issues, whereas with

4 days off, the metals wouldn't have too much time to redistribute

before the chelator is working again.

Any opinions or experience with the dosing schedules would be

appreciated. Thank you.

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