Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 Hi , Sorry to jump in but -- By dosing every hour, you would be increasing the overall amount of chelator OR are you saying to lower the chelator dosage and chelate more frequently? Cochran <Ladyshrink111@...> wrote: Andy, Is it appropriate to vary the dosing interval of the chelator, mostly given on 3 hours, but moved up occasionally to 2 hours or even 1 hour for dosing convenience or not to interrupt things? This is not 2 hours consistently but 3, then 2, then 3, etc. It was my understanding that it didn't matter as long as the doses were not more than three hours apart. Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 No, not saying to lower the dose, same dose, given an hour or an hour an half early for convenience purposes. Glad to hear anyone's take on this as we have done it this way from the beginning. Having trouble (me) making this clear, but not dosing every hour on the hour, just occassionally giving the chelator early so that she can go play with her friends or participate in her ballet class without interruption. Re: [ ] ANDY-Dosing Interval Hi , Sorry to jump in but -- By dosing every hour, you would be increasing the overall amount of chelator OR are you saying to lower the chelator dosage and chelate more frequently? Cochran <Ladyshrink111@...> wrote: Andy, Is it appropriate to vary the dosing interval of the chelator, mostly given on 3 hours, but moved up occasionally to 2 hours or even 1 hour for dosing convenience or not to interrupt things? This is not 2 hours consistently but 3, then 2, then 3, etc. It was my understanding that it didn't matter as long as the doses were not more than three hours apart. Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 My opinion is that if you are " averaging " close to the correct TOTAL chelator for a 24 hour period AND you are not exceeding 4 hours between doses (for ALA) you can probably get away with this. My feeling is that the more you vary the timing, the more the amount of chelator in the blood will fluctuate causing the person to " feel odd " compared to a " normal " round. Neil _____ From: [mailto: ] On Behalf Of Cochran Sent: Tuesday, January 09, 2007 10:26 AM Subject: Re: [ ] ANDY-Dosing Interval No, not saying to lower the dose, same dose, given an hour or an hour an half early for convenience purposes. Glad to hear anyone's take on this as we have done it this way from the beginning. Having trouble (me) making this clear, but not dosing every hour on the hour, just occassionally giving the chelator early so that she can go play with her friends or participate in her ballet class without interruption. Re: [ ] ANDY-Dosing Interval Hi , Sorry to jump in but -- By dosing every hour, you would be increasing the overall amount of chelator OR are you saying to lower the chelator dosage and chelate more frequently? Cochran <Ladyshrink111@ <mailto:Ladyshrink111%40peoplepc.com> peoplepc.com> wrote: Andy, Is it appropriate to vary the dosing interval of the chelator, mostly given on 3 hours, but moved up occasionally to 2 hours or even 1 hour for dosing convenience or not to interrupt things? This is not 2 hours consistently but 3, then 2, then 3, etc. It was my understanding that it didn't matter as long as the doses were not more than three hours apart. Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 10, 2007 Report Share Posted January 10, 2007 > Having trouble (me) making this clear, but not dosing every hour on the hour, just occassionally giving the chelator early so that she can go play with her friends or participate in her ballet class without interruption. Yes, exactly. I aim for every 2.5 hours but often something gets in the way and I go to 2 hrs or 3 hrs. I haven't noticed any problems doing it this way, but over on the adult list a while back people were warning against it, so I've been wondering. Nell Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 10, 2007 Report Share Posted January 10, 2007 Thanks for weighing in on this, Neil, she is fully verbal and has never complained of feeling odd or acted in anyway as if it affected her one way or another. When we increased the Ala to full dose (just a 4 mg increase) she did complain that her head felt funny but it was not a time when we were shortening the times. So I know she would say something and we're pretty good at observing her behavior aka " watching her like a hawk " during a round for any discernible differences. We do try to " split " the difference when we know that we are going to want to give a dose at 5pm when we have just given a dose at 12pm, or a 5 hour interval rather than a 6 hour, and give the next two doses at 2.5 hour intervals. We NEVER exceed 3 hours for Ala, are compulsive about this, 4 hours at night. We wouldn't shorten the time either if we thought there was any chance it was unadvisable and maybe we were too literal with Andy's comment that the only thing that mattered was not going longer than the 3 hour dosing. Re: [ ] ANDY-Dosing Interval Hi , Sorry to jump in but -- By dosing every hour, you would be increasing the overall amount of chelator OR are you saying to lower the chelator dosage and chelate more frequently? Cochran <Ladyshrink111@ <mailto:Ladyshrink111%40peoplepc.com> peoplepc.com> wrote: Andy, Is it appropriate to vary the dosing interval of the chelator, mostly given on 3 hours, but moved up occasionally to 2 hours or even 1 hour for dosing convenience or not to interrupt things? This is not 2 hours consistently but 3, then 2, then 3, etc. It was my understanding that it didn't matter as long as the doses were not more than three hours apart. Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 10, 2007 Report Share Posted January 10, 2007 We also try to split the difference to make consistent intervals when we want to bump things up. It doesn't seem to present a problem. We just make sure we never go more than 3 hours during the day, 4 at night. At some level, some of this is academic. For example, it seems to me that when the chelator is given on an empty stomach, it will likely get into the blood stream faster than when dosing coincides with meal time. So, what is perfect on paper will vary under real life conditions. Anne > Andy, > > Is it appropriate to vary the dosing interval of the chelator, mostly given > on 3 hours, but moved up occasionally to 2 hours or even 1 hour for dosing > convenience or not to interrupt things? This is not 2 hours consistently but > 3, then 2, then 3, etc. > > It was my understanding that it didn't matter as long as the doses were not > more than three hours apart. > > Thanks, > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 3, 2007 Report Share Posted February 3, 2007 > > Andy, > > Is it appropriate to vary the dosing interval of the chelator, mostly given on 3 hours, but moved up occasionally to 2 hours or even 1 hour for dosing convenience or not to interrupt things? This is not 2 hours consistently but 3, then 2, then 3, etc. > > It was my understanding that it didn't matter as long as the doses were not more than three hours apart. You are correct, this is fine. > > Thanks, > > > Quote Link to comment Share on other sites More sharing options...
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