Fwd: High Amino Acids

[Guest guest]

Hi All

Have a few queries and would certainly appreciate if the list members could

help us with it :

We recently did an amino acid screening for our 4 1/2 year old son and

found that glycine was 526; and tryptophan, ornithine and arginine were also

moderately elevated. This was done using the HPLC method with Norleucine as

the internal standard. Would be grateful if somebody could interpret this

result for us. We live in India and do not have any DAN doctor, with us

here.

At the time of the test we were giving him ISOGEST digestive enzymes.

Taurine 500 and probiotics. We had also given a dose of Flagyl that was

completed three days prior to the test.

The second question is that with such a high glycine level is it still OK to

start him on DMG. We are keen to start on DMG but do not know if the glycine

in it will further push up the levels.

The third question: how do we check if our son has over-methylation. We had

been giving him MB12 subcutanous shots for 4 months, and stopped it about a

month prior to the test. there appeared to be no significant change in his

behaviour/cognition/skills.

I am typing out the test results for you. I shall attach the graphic

representation of the tests ( organic acids and amino acids; though in

organic acid test, It may not have been done as per DAN! specifications,

mainly because we do not know what to look for!)

Here it is :

glutamic acid - 84

Aspartic acid - ND

Serine - 133

Aspargine - ==

Glycine - 526

b ALA - ==

Histadine - 99

Citrulline - 12

Norleucine - Internal std

Alanine - 297

Arginine - 123

Tryosine - 63

Methionine - 24

Cysteine - 25

Isoleucine - 49

Leucine - 86

Phenylalanine - 62

Tryptophan - == (But in the report and the graph he has said it is high)

Ornithine - 212

Lysine - 146

Please note this test was done at about 1400hours and he had had a

light lunch of rice, veggies and chicken. I do not know how it would

have affected the results. Also I am not sure if we have to take the

race issue into account (i.e. Indian genetic make up and eating habits

etc) before we can compare with control group results or standards.

Thanks in advance

Ajai