Re: Dental amalgam oral lesions - Is this candida?

[Guest guest]

Does anyone know if these oral lesions are the same thing as oral

thrush. I have them and they seem to read like they are the same? I

take it that chelation will eventually resolve the issue, does any

one know?

Thanks

Phil

>

> Dental amalgam is a common cause of oral and systemic cancers

>

> It has been well documented in the medical literature that immune

reactivity to mercury in dental amalgam is the most common cause of

oral lichen planus , oral lichen lesions, and other oral lesions, and

that most who have their amalgam fillings replaced recover(45).

> Oral lichen planus and oral lesions are inflammatory pre-cancerous

conditions that have been well documented in the literature to often

develop into oral squamous cell carcinoma(OSCC)(46). Infection and

chronic inflammation have been found to contribute to carcinogenesis

through inflammation-related mechanisms(47,48). Inflammatory bowel

diseases are associated with colon carcinogenesis and inflammatory

oral conditions such as oral lichen planus (OLP) and leukoplakia are

associated with OSCC.

> Previous studies have shown significant increases of NF-kappaB

dependent cytokines, Tumor Necrosis Factor-alpha(TNF-a), IL-1alpha,

IL-6, and IL-8 in different oral fluids from oral lichen planus (OLP)

patients(48). In samples of whole unstimulated saliva in this study,

for moderate and severe OLP dysplasia, the level of each cytokine was

significantly higher than in control. In moderate dysplasia, TNF-

alpha and IL-1alpha were significantly increased at a level without

difference from OSCC, but IL-6 and IL-8 was detected at a

concentration significantly lower than OSCC. In severe OLP dysplasia,

the level of TNF-alpha was not significantly different from that of

Oral Squamous Cell Carcinoma. The study confirmed preclinical data

that NF-kappaB dependent cytokines are upregulated in pre-malignant

OLP and oral carcinogenesis. Cytologic and DNA-cytometric

examination of oral lesions and oral lichen planus have also been

found to be reliable indicators of OLP cases becoming malignant(49).

Immunolabeled oncoproteins were found to b modified in the

premalignant leukoplakia, oral lichen planus and in squamous cell

cancer(49,46a).

> The evidence supports that dental amalgam is the most common cause

of oral squamous cell carcinoma, similar to the fact it is the most

common cause of OLP. The available pretreatment dental records of 133

patients with carcinoma of the tongue seen at the British Columbia

Cancer Agency between 1958 and 1992 were reviewed. The majority had

amalgam fillings on the side of the tongue involved in the

carcinoma. Of the 7 patients with amalgams on only one side of the

mouth, 6 cases of oral cancer had amalgams on the side of the cancer

and only 1 on the side without amalgams(50).

> People with oral lichen planus often develop OLP at multiple

sites(51) and also can have lichen planus in other locations such as

the esophagus(52) or genitals(53). In one study 41 women diagnosed

with OLP underwent gynecological exam and 75.6% were found to have

evidence of genital involvement, vulvar lichen planus or vulvar

lichen sclerosis(53b). Such inflammatory conditions can also become

cancerous(52,54). Two siblings with long standing cutaneous lichen

planus of the esophagus both developed squamous cell carcinoma(52).

Since immune reactivity to mercury is the most common cause of OLP

and OSCC and since immune reactivity to mercury is a systemic

condition (37,etc.), systemic immune reactivity to mercury might be

the most likely cause of lichen planus and resulting squamous cell

cancers of other organs such as the esophagus and genitals.

>

> References:

> www.home.earthlink.net/~berniew1/olp.html

>

> (I'm not aware of any credible scientists or doctors who dispute

this, yet its little known)

>