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Re: Stool test and enzymes?

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My opinion is that if the enzymes are helping your child, keep giving

them. I believe it was who pointed out in a similar case

posted here that the test would be more helpful if you keep the child

on enzymes. I would ask what would taking the child off of something

that helps accomplish? You may get better information about what

else the child needs in addition to enzymes if you do the testing

with the child remains on enzymes.

Also, you might ask what exactly the tests would reliably indicate

with or without enzymes and what research there is to back this.

> I am currently working with Pfeiffer and have requested a

> comprehensive stool and OAT tests to be done this week. The

> instructions say to not give digestive enzymes two days before and

> during the stool collection (3 days). Has anyone had the

experience

> of stopping the enzymes for five days and then re-start? I imagine

> there is a need to ramp up again if this is necessary.

>

> Hoping that we could do this on enzymes as they are making a

positive

> difference in daughter's life.

>

> Anyone?

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> >

> Hi ,

Thank you for your reply. I really couldn't imagine what the

rationale is for this - but I'm more of a pragmatist. Don't mess

with something that is working!

Blessings,

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I would call and ask them for their rationale.

Hope everything goes well.

> > >

> > Hi ,

>

> Thank you for your reply. I really couldn't imagine what the

> rationale is for this - but I'm more of a pragmatist. Don't mess

> with something that is working!

>

> Blessings,

>

>

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Hi ,

After speaking to DDI, their rationale is that enzymes can produce

false positives/negatives. We must stay off them the entire time

(hopefully just five days). Oh well, I guess we'll just grin and

bear it! (Did I really say that!)

thanks again,

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False positives or negatives for what?

>

> Hi ,

>

> After speaking to DDI, their rationale is that enzymes can produce

> false positives/negatives. We must stay off them the entire time

> (hopefully just five days). Oh well, I guess we'll just grin and

> bear it! (Did I really say that!)

>

> thanks again,

>

>

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Just found my notes from that conversation. It's " camotrimson " that

they're worried about.

>

> Hi ,

>

> After speaking to DDI, their rationale is that enzymes can produce

> false positives/negatives. We must stay off them the entire time

> (hopefully just five days). Oh well, I guess we'll just grin and

> bear it! (Did I really say that!)

>

> thanks again,

>

>

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I certainly do not want to imply anything negative about any testing lab,

but.....

Actually, testing for chymotrypsin should not be hindered by taking enzyme

supplements.

The reason is, there are very, very specific synthetic substrates for enzymes

that are

available to any lab. In fact, that is how one is able to differentiate between

proteases

such as trypsin, pepsin, or chymotrypsin; by using these substrates that only

work with

one substrate.

I'm also not real keen on fecal testing for enzymes; there is just too much time

and other

factors going on between the duodenum and the rectum, not too mention the delay

in

shipping the materials and preparing for testing.

I developed enzyme assays all the time, if any lab needs help in developing a

better test,

I'll be glad to consult and help.

Devin Houston, Ph.D.

> I am currently working with Pfeiffer and have requested a

> comprehensive stool and OAT tests to be done this week. The

> instructions say to not give digestive enzymes two days before and

> during the stool collection (3 days). Has anyone had the experience

> of stopping the enzymes for five days and then re-start? I imagine

> there is a need to ramp up again if this is necessary.

>

> Hoping that we could do this on enzymes as they are making a positive

> difference in daughter's life.

>

> Anyone?

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Forgive me Dr. Houston,

Are you saying there should be no compromise of the comprehensive

stool test while staying on AFT-PEP, ZP, and NF?

My understanding of the stool test is to get a good reading on

bacteria, etc.

Thank you for any help you can give,

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I'm not sure what all the comp. stool test is for, but I was only addressing the

issue of

whether pancreatic enzymes, such as chymotrypsin, are affected by oral enzymes.

Since we have pancreatic enzymes in our gut anyway, I don't think additional

enzyme

supplements in the gut would have an effect on bacteria levels, either.

> Forgive me Dr. Houston,

>

> Are you saying there should be no compromise of the comprehensive

> stool test while staying on AFT-PEP, ZP, and NF?

>

> My understanding of the stool test is to get a good reading on

> bacteria, etc.

>

> Thank you for any help you can give,

>

>

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