Re: question about DMSO in DMSA

[Guest guest]

,

We had a horrible reaction with DMSA that was compounded for us at a local

Southern CA pharmacy. We were assured that there was no corn, soy, casein or

gluten in the powder they mixed. They said they used calcium carbonate.

Leah's reaction to their DMSA was hives. She only gets hives from corn.

I ordered some DMSA capsules from VRP and Leah did not have any adverse

reactions. Maybe it is that tree-based ingredient (DMSO) or, maybe, it is

something else in the compound.

You might consider giving that a try, if you still want to use DMSA as your

chelator.

Leah is currently having rashes and some sinus congestion - which I am

attributing to the DMSA, as a known-side effect. Behavior is a bit more

oppositional than usual and activity level is higher. Life is still

manageable, however. We don't see any regression. Leah is on the higher end

of HFA.

I hope this helps.

--

Rima Regas

Mom to Leah, age 8 (AS, DSI and APD)

http://www.sensoryintegrationhelp.com

On 1/23/06, cindyroyster <cindyroyster@...> wrote:

>

> I've been posting about my son's regression after his second round of

> DMSA. I am now beginning to wonder about the DMSO in his DMSA from

> Coastal Compounding. I know that DMSO is from trees and is sulfur-

> containing which most of our kids need. However, we put my son on

> Moducare (tree product also) that was suppose to help regulate his

> immune system. He had the same type of regression which resolved

> after stopping. Has anyone else had this experience and I am now

> wondering if this could be a source of our problem. My son has NEVER

> had lasting regression and always returned to normal after stopping

> certain supplements. When my family saw him this weekend they

> couldn't believe the change. This was a boy who was so happy, asked

> so many questions, and loved to share things and stories with others.

> That has all gone away in a matter of 2 rounds...he has a flat affect

> and does not talk as much with few questions. His mood is somewhat

> improved since stopping nasal B12 with folinic (already on MB12). Any

> comments on DMSO? I am desperately searching for answers.

>

>

>

>

>

>

>

> =======================================================

>

[Guest guest]

I know using DMSO by itself, rubbed on the skin, will cause mercury to

mobilize and not be chelated in many people. It will just move mercury

around and many people that are mercury toxic get severe liver reactions

from DMSO (start waking up at 3am, liver time... emotional, angry, etc).

Since DMSO easily passes through the skin, they use it as the transdermal

agent in TD-DMSA, and I suppose they figure the DMSA must bind anything that

is mobilized, but if I had a bad reaction I sure would switch to oral DMSA.

Cheers,

_____

From: [mailto: ]

On Behalf Of cindyroyster

Sent: Monday, January 23, 2006 11:01 PM

Subject: [ ] question about DMSO in DMSA

I've been posting about my son's regression after his second round of

DMSA. I am now beginning to wonder about the DMSO in his DMSA from

Coastal Compounding. I know that DMSO is from trees and is sulfur-

containing which most of our kids need. However, we put my son on

Moducare (tree product also) that was suppose to help regulate his

immune system. He had the same type of regression which resolved

after stopping. Has anyone else had this experience and I am now

wondering if this could be a source of our problem. My son has NEVER

had lasting regression and always returned to normal after stopping

certain supplements. When my family saw him this weekend they

couldn't believe the change. This was a boy who was so happy, asked

so many questions, and loved to share things and stories with others.

That has all gone away in a matter of 2 rounds...he has a flat affect

and does not talk as much with few questions. His mood is somewhat

improved since stopping nasal B12 with folinic (already on MB12). Any

comments on DMSO? I am desperately searching for answers.

=======================================================

[Guest guest]

What was the dosing schedule you used? Every 8 hours, or every 4?

[ ] question about DMSO in DMSA

I've been posting about my son's regression after his second round of

DMSA. I am now beginning to wonder about the DMSO in his DMSA from

Coastal Compounding. I know that DMSO is from trees and is sulfur-

containing which most of our kids need. However, we put my son on

Moducare (tree product also) that was suppose to help regulate his

immune system. He had the same type of regression which resolved

after stopping. Has anyone else had this experience and I am now

wondering if this could be a source of our problem. My son has NEVER

had lasting regression and always returned to normal after stopping

certain supplements. When my family saw him this weekend they

couldn't believe the change. This was a boy who was so happy, asked

so many questions, and loved to share things and stories with others.

That has all gone away in a matter of 2 rounds...he has a flat affect

and does not talk as much with few questions. His mood is somewhat

improved since stopping nasal B12 with folinic (already on MB12). Any

comments on DMSO? I am desperately searching for answers.

=======================================================

[Guest guest]

,

You can buy DMSA on your own. Is there a particular reason you're having it

compounded?

S S

<tt>

I've been posting about my son's regression after his second round of <BR>

DMSA.  I am now beginning to wonder about the DMSO in his DMSA from <BR>

Coastal Compounding.  I know that DMSO is from trees and is sulfur-<BR>

containing which most of our kids need.  However, we put my son on <BR>

Moducare (tree product also) that was suppose to help regulate his <BR>

immune system.  He had the same type of regression which resolved <BR>

after stopping.  Has anyone else had this experience and I am now <BR>

wondering if this could be a source of our problem.  My son has NEVER <BR>

had lasting regression and always returned to normal after stopping <BR>

certain supplements.  When my family saw him this weekend they <BR>

couldn't believe the change.  This was a boy who was so happy, asked <BR>

so many questions, and loved to share things and stories with others.  <BR>

That has all gone away in a matter of 2 rounds...he has a flat affect <BR>

and does not talk as much with few questions.  His mood is somewhat <BR>

improved since stopping nasal B12 with folinic (already on MB12).  Any <BR>

comments on DMSO?  I am desperately searching for answers.<BR>

<BR>

<BR>

_______________________________________________

Join Excite! - http://www.excite.com

The most personalized portal on the Web!

[Guest guest]

I wanted to use TD instead of oral because of the higher risk for

gut problems with oral. He seems sensitive to oral supplements taht

can aggravate yeast. We are continuing to fight the yeast battle.

>

> <tt>

> I've been posting about my son's regression after his second round

of <BR>

> DMSA.  I am now beginning to wonder about the DMSO in his DMSA

from <BR>

> Coastal Compounding.  I know that DMSO is from trees and is sulfur-

<BR>

> containing which most of our kids need.  However, we put my son on

<BR>

> Moducare (tree product also) that was suppose to help regulate his

<BR>

> immune system.  He had the same type of regression which resolved

<BR>

> after stopping.  Has anyone else had this experience and I am now

<BR>

> wondering if this could be a source of our problem.  My son has

NEVER <BR>

> had lasting regression and always returned to normal after

stopping <BR>

> certain supplements.  When my family saw him this weekend they <BR>

> couldn't believe the change.  This was a boy who was so happy,

asked <BR>

> so many questions, and loved to share things and stories with

others.  <BR>

> That has all gone away in a matter of 2 rounds...he has a flat

affect <BR>

> and does not talk as much with few questions.  His mood is

somewhat <BR>

> improved since stopping nasal B12 with folinic (already on MB12). 

Any <BR>

> comments on DMSO?  I am desperately searching for answers.<BR>

> <BR>

> <BR>

>

>

> _______________________________________________

> Join Excite! - http://www.excite.com

> The most personalized portal on the Web!

>

[Guest guest]

Hello , I know the last thing you want to do is start another

supplement - but what I think happed is you sons gut got thrown off

balance and does not have either the right flora in it or enough

serotonin or his pH is off... it could be alittle of all of that - it

could have nothing to do with the chelation - it just happed at the

same time ( I would not use the chelation products again there is a

fifty fifty chance it was the sulfer) - I would use ALA on a every 3

hours for 3 days 25 mg dose. My son would have his best days when on

ALA back then.

Don't get too scared you must move forwards I will leave you with

some reading about the function of the gut and the 5HTP I think you

should give your son, for his pH I suggest a tablespoon of cranberry

juice twice a day- the pH changes almost hour to hour it is when is

stays either to acid or too alkaline there is the problem. I will have

to do another post with the web pages links -there are not on the

computer. My 2 cents Ann

[Guest guest]

http://www.hosppract.com/issues/1999/07/gershon.htm

http://www.enzymestuff.com/serotonin.htm

http://www.incrediblehorizons.com/digestion%20 & %20autistic%

20children.htm

http://wiz2.pharm.wayne.edu/biochem/enz.html

in case you have not read this one.

http://puterakembara.org/rm/Dr_Jepson.pdf

[Guest guest]

> That has all gone away in a matter of 2 rounds...he has a flat affect

> and does not talk as much with few questions.

Could you switch to oral DMSA? You're giving it every 4 hours or more

often? It does seem like the various additives to TD products cause a

lot of problems, whether it's the DMSO or the glut or whatever.

Nell

[Guest guest]

,

Go with Lee Silsby and see if that makes a difference. They do not

use DMSO with the TD-DMSA. It is expensive ($120 for 3 rounds of 3

on/4 off for us), but I have been very happy with their product AND

their customer service.

Sorry you are faced with this regression.

Pam

> >

> > <tt>

> > I've been posting about my son's regression after his second

round

> of <BR>

> > DMSA.  I am now beginning to wonder about the DMSO in his DMSA

> from <BR>

> > Coastal Compounding.  I know that DMSO is from trees and is

sulfur-

> <BR>

> > containing which most of our kids need.  However, we put my son

on

> <BR>

> > Moducare (tree product also) that was suppose to help regulate

his

> <BR>

> > immune system.  He had the same type of regression which

resolved

> <BR>

> > after stopping.  Has anyone else had this experience and I am

now

> <BR>

> > wondering if this could be a source of our problem.  My son has

> NEVER <BR>

> > had lasting regression and always returned to normal after

> stopping <BR>

> > certain supplements.  When my family saw him this weekend they

<BR>

> > couldn't believe the change.  This was a boy who was so happy,

> asked <BR>

> > so many questions, and loved to share things and stories with

> others.  <BR>

> > That has all gone away in a matter of 2 rounds...he has a flat

> affect <BR>

> > and does not talk as much with few questions.  His mood is

> somewhat <BR>

> > improved since stopping nasal B12 with folinic (already on

MB12). 

> Any <BR>

> > comments on DMSO?  I am desperately searching for answers.<BR>

> > <BR>

> > <BR>

> >

> >

> > _______________________________________________

> > Join Excite! - http://www.excite.com

> > The most personalized portal on the Web!

> >

>

[Guest guest]

>

> I wanted to use TD instead of oral because of the higher risk for

> gut problems with oral. He seems sensitive to oral supplements taht

> can aggravate yeast. We are continuing to fight the yeast battle.

But at least you can treat yeast, and people still get it with TD anyway.

Nell

[Guest guest]

> >

> >

> > ,

> > You can buy DMSA on your own. Is there a particular reason you're

> having it compounded?

> > S S

> >

[Guest guest]

: I agree with Pam. We started out with Coastal's TD-DMSA

every weekend. After 4 weeks, huge regression...although I dont

think the regression was due to the DMSA.

BUT...I did call Coastal to talk to them about their DMSA product and

the DMSO in it. The pharmacist said they have been having " some "

problems with their TD-DMSA and only receiving mild positive

results. However, he is receiving HUGE positive reactions from

parents regarding their TD-ALA.

We switched to Lee Silsby's TD-DMSA and have had few problems, but

yes...it is more expensive. I have Coastal's TD-ALA in the fridge

right now, and plan to use it after the 10th round!

Good luck...Kim

> > >

> > > <tt>

> > > I've been posting about my son's regression after his second

> round

> > of <BR>

> > > DMSA.  I am now beginning to wonder about the DMSO in his DMSA

> > from <BR>

> > > Coastal Compounding.  I know that DMSO is from trees and is

> sulfur-

> > <BR>

> > > containing which most of our kids need.  However, we put my son

> on

> > <BR>

> > > Moducare (tree product also) that was suppose to help regulate

> his

> > <BR>

> > > immune system.  He had the same type of regression which

> resolved

> > <BR>

> > > after stopping.  Has anyone else had this experience and I am

> now

> > <BR>

> > > wondering if this could be a source of our problem.  My son has

> > NEVER <BR>

> > > had lasting regression and always returned to normal after

> > stopping <BR>

> > > certain supplements.  When my family saw him this weekend they

> <BR>

> > > couldn't believe the change.  This was a boy who was so happy,

> > asked <BR>

> > > so many questions, and loved to share things and stories with

> > others.  <BR>

> > > That has all gone away in a matter of 2 rounds...he has a flat

> > affect <BR>

> > > and does not talk as much with few questions.  His mood is

> > somewhat <BR>

> > > improved since stopping nasal B12 with folinic (already on

> MB12). 

> > Any <BR>

> > > comments on DMSO?  I am desperately searching for answers.<BR>

> > > <BR>

> > > <BR>

> > >

> > >

> > > _______________________________________________

> > > Join Excite! - http://www.excite.com

> > > The most personalized portal on the Web!

> > >

> >

>

[Guest guest]

Thanks!

> > > >

> > > > <tt>

> > > > I've been posting about my son's regression after his second

> > round

> > > of <BR>

> > > > DMSA.  I am now beginning to wonder about the DMSO in his

DMSA

> > > from <BR>

> > > > Coastal Compounding.  I know that DMSO is from trees and is

> > sulfur-

> > > <BR>

> > > > containing which most of our kids need.  However, we put my

son

> > on

> > > <BR>

> > > > Moducare (tree product also) that was suppose to help

regulate

> > his

> > > <BR>

> > > > immune system.  He had the same type of regression which

> > resolved

> > > <BR>

> > > > after stopping.  Has anyone else had this experience and I

am

> > now

> > > <BR>

> > > > wondering if this could be a source of our problem.  My son

has

> > > NEVER <BR>

> > > > had lasting regression and always returned to normal after

> > > stopping <BR>

> > > > certain supplements.  When my family saw him this weekend

they

> > <BR>

> > > > couldn't believe the change.  This was a boy who was so

happy,

> > > asked <BR>

> > > > so many questions, and loved to share things and stories

with

> > > others.  <BR>

> > > > That has all gone away in a matter of 2 rounds...he has a

flat

> > > affect <BR>

> > > > and does not talk as much with few questions.  His mood is

> > > somewhat <BR>

> > > > improved since stopping nasal B12 with folinic (already on

> > MB12). 

> > > Any <BR>

> > > > comments on DMSO?  I am desperately searching for

answers.<BR>

> > > > <BR>

> > > > <BR>

> > > >

> > > >

> > > > _______________________________________________

> > > > Join Excite! - http://www.excite.com

> > > > The most personalized portal on the Web!

> > > >

> > >

> >

>

[Guest guest]

Will they compound it without the DMSO?

S S

<tt>

I wanted to use TD instead of oral because of the higher risk for <BR>

gut problems with oral.  He seems sensitive to oral supplements taht <BR>

can aggravate yeast.  We are continuing to fight the yeast battle.<BR>

<BR>

<BR>

<BR>

><BR>

> <BR>

> ,<BR>

> You can buy DMSA on your own.  Is there a particular reason you're <BR>

having it compounded?  <BR>

> S S<BR>

> <BR>

_______________________________________________

Join Excite! - http://www.excite.com

The most personalized portal on the Web!

[Guest guest]

Has your child done better since switching from Coastal? Did the

regression stop?

> > > > >

> > > > > <tt>

> > > > > I've been posting about my son's regression after his

second

> > > round

> > > > of <BR>

> > > > > DMSA.  I am now beginning to wonder about the DMSO in his

> DMSA

> > > > from <BR>

> > > > > Coastal Compounding.  I know that DMSO is from trees and

is

> > > sulfur-

> > > > <BR>

> > > > > containing which most of our kids need.  However, we put

my

> son

> > > on

> > > > <BR>

> > > > > Moducare (tree product also) that was suppose to help

> regulate

> > > his

> > > > <BR>

> > > > > immune system.  He had the same type of regression which

> > > resolved

> > > > <BR>

> > > > > after stopping.  Has anyone else had this experience and I

> am

> > > now

> > > > <BR>

> > > > > wondering if this could be a source of our problem.  My

son

> has

> > > > NEVER <BR>

> > > > > had lasting regression and always returned to normal after

> > > > stopping <BR>

> > > > > certain supplements.  When my family saw him this weekend

> they

> > > <BR>

> > > > > couldn't believe the change.  This was a boy who was so

> happy,

> > > > asked <BR>

> > > > > so many questions, and loved to share things and stories

> with

> > > > others.  <BR>

> > > > > That has all gone away in a matter of 2 rounds...he has a

> flat

> > > > affect <BR>

> > > > > and does not talk as much with few questions.  His mood is

> > > > somewhat <BR>

> > > > > improved since stopping nasal B12 with folinic (already on

> > > MB12). 

> > > > Any <BR>

> > > > > comments on DMSO?  I am desperately searching for

> answers.<BR>

> > > > > <BR>

> > > > > <BR>

> > > > >

> > > > >

> > > > > _______________________________________________

> > > > > Join Excite! - http://www.excite.com

> > > > > The most personalized portal on the Web!

> > > > >

> > > >

> > >

> >

>

[Guest guest]

I'm not sure but I know that I can get it from another compounding

pharmacy without the DMSO.

<BR>

> ><BR>

> > <BR>

> > ,<BR>

> > You can buy DMSA on your own.  Is there a particular reason

you're <BR>

> having it compounded?  <BR>

> > S S<BR>

> > <BR>

>

>

> _______________________________________________

> Join Excite! - http://www.excite.com

> The most personalized portal on the Web!

>

[Guest guest]

> I am now beginning to wonder about the DMSO in his DMSA

I remember a few years ago some other parents complaining about the DMSO in

transdermal stuff.

I am sorry I don't remember details, but just so you know, others had problems

with DMSO too.

Did you say that you were giving methylB12 and nasal B12? Or did I get that

wrong? (no connection with DMSO, but just curious)

Valentina

[Guest guest]

DMSO as a carrier for DMSA just seems a little scary to me. Seems you would

need to have the portions just right to make sure enough DMSA got carried

through the body to bind any mercury that was methylated by the DMSO.

DMSO by itself is not a good mercury chelator, it can just drag mercury

around, and Andy Cutler mentions this in his book.

The DM in DMSO and DMSA do not stand or the same thing. The DM in DMSA

stands for Di (2 in latin) Mercaptan (mercury capture, the name for

sulphur). 2 mercaptans is usually a good chelator. The DM in DMSO stands for

Di (2 again) Methyl, which means is has 2 methyl groups, and then sulphur

and oxygen.

If you rub 30% DMSO on your hands (like Tree of Life DMSO, 30% DMSO, 70%

distilled water), you can taste the sulphur DMSO in your mouth sometimes in

30 seconds.

If you pour DMSO on a coffee bean in your hand, sometimes you taste coffee

in your mouth, and sometimes you just taste the DMSO sulphur/garlic taste.

When you don't taste the coffee to me that means the substance you mixed it

with (coffee in this case) didn't get carried as far as the DMSO. This would

seem to me to be the same thing when you mix DMSO with DMSA, maybe the DMSA

doesn't get carried as far as the DMSO, which seems dangerous.

Without the presence of mercury, DMSO is a pretty amazing substance. There

is a good article on it at medical-library.net. We used to use it all the

time to get rid of bruises and excellerate healing, but noticed that many

people had poor reactions to it, especially those with amalgams or high

mercury levels.

Just thinking out loud.

Cheers,

_____

From: [mailto: ]

On Behalf Of Valentina Scharpf

Sent: Wednesday, January 25, 2006 12:25 PM

Subject: Re: [ ] question about DMSO in DMSA

> I am now beginning to wonder about the DMSO in his DMSA

I remember a few years ago some other parents complaining about the DMSO in

transdermal stuff.

I am sorry I don't remember details, but just so you know, others had

problems

with DMSO too.

Did you say that you were giving methylB12 and nasal B12? Or did I get that

wrong? (no connection with DMSO, but just curious)

Valentina

=======================================================

[Guest guest]

I called the pharmacy about the DMSO. They said that it is a sulfur-

containing product (which I already knew) and that they haven't

really had any problems with it. They said that the sulfur products

usually help these kids out. But it did not help my son out and I

cannot continue to give him something that has caused such severe

regression...he is improving daily since stopping but not yet to

baseline. Yes, we were giving MB12 injections and B12 nasal spray

because his last OAT test showed that he needed more B12...he

obviously has a problem absorbing or knowing what to do with B12 but

he does very, very well on it. I stopped the nasal B12 because I

think he was having problems with the folinic acid in the nasal

spray...I know of others having this problem also. If anyone has

suggestions on the sulfur issue feel free to give your 2 cents. We

had the genomic detox profile done which was normal except for GSH

was NULL...so the phasse II was normal. Thanks.

>

> > I am now beginning to wonder about the DMSO in his DMSA

>

> I remember a few years ago some other parents complaining about

the DMSO in

> transdermal stuff.

> I am sorry I don't remember details, but just so you know, others

had problems

> with DMSO too.

>

> Did you say that you were giving methylB12 and nasal B12? Or did I

get that

> wrong? (no connection with DMSO, but just curious)

>

>

> Valentina

>