Re: Oops - I goofed! What do I do now?

[Guest guest]

>

> I started a round today and messed up. I spaced and applied the full

> dose as my DAN wrote it instead of splitting it in half! If I am

> doing the four hour schedule, I need to apply again in one hour. Do I

> just apply the next dose properly

Yes.

> and go on about the round and just

> be one dose short?

Just go to the end of the round. Don't adjust length.

> Will that cause problems with redistribution

> because I am only applying 1/2 the chelator that I applied last time?

> How big of a deal is this?

Probably not too big but you'll have to wait to be sure.

> Thanks for any quick info.

>

>

[Guest guest]

> I started a round today and messed up. I spaced and applied the full

> dose as my DAN wrote it instead of splitting it in half!

I always start the chelation by taking 2 doses of the chelator at once.

Valentina

[Guest guest]

>

> I always start the chelation by taking 2 doses of the chelator at

once.

Why?

[Guest guest]

> > I always start the chelation by taking 2 doses of the chelator at

> once.

>

> Why?

You reach the desired level of chelator faster.

Somebody else do the math please if I am wrong...

Valentina

[Guest guest]

But then if you don't maintain that dose then aren't you recirculating

metals?

>

> > > I always start the chelation by taking 2 doses of the chelator at

> > once.

> >

> > Why?

>

> You reach the desired level of chelator faster.

> Somebody else do the math please if I am wrong...

>

>

> Valentina

>

[Guest guest]

> But then if you don't maintain that dose then aren't you recirculating

> metals?

No no.... it's not really like that... How do I explain this? My English is

not good enough

When you start a chelation round, it takes about 3-4 doses until the levels

of chelator in your blood become stable. And this is not to say that you

have the same amount of chelator in the blood every minute; the levels

fluctuate all the time. But the idea is to have less fluctuation, and to

try to maintain certain levels. I am sorry, I just don't know how to

explain this...

If you take into consideration the half life of the chelator, you will

realize that after 4 hours (for DMSA) for example, you will only have half

of the initial dose in your blood. You take another dose and then you will

have... do the math.... After another 4 hours, you have half of that and

you take another dose...

If you start with a double dose you reach the desired level faster.

I am sorry if this was not clear. I really am not good at explaining

this...

Valentina

> > > > I always start the chelation by taking 2 doses of the chelator at

> > > once.

> > >

> > > Why?

> >

> > You reach the desired level of chelator faster.

> > Somebody else do the math please if I am wrong...

> >

> >

> > Valentina

> >

>

> =======================================================

>

[Guest guest]

>

> But then if you don't maintain that dose then aren't you

recirculating

> metals?

>

> > > > I always start the chelation by taking 2 doses of the

chelator at

> > > once.

> > >

The is my understanding:

The first dose is increasing chelator body levels from " 0 " .

Subsequent doses are adding to a level of approximately " 1/2 " . (I

understand the half-life of DMSA to be 3+ hours) Thus, the peak

level after the first dose is lower than subsequent peaks if using

flat dosing. Valentina's double dose to start has logic behind it,

although I believe that a " 1 1/2 " dose would equalize peak levels

more precisely. I'd appreciate if Andy could comment on this.

[Guest guest]

> flat dosing. Valentina's double dose to start has logic behind it,

> although I believe that a " 1 1/2 " dose would equalize peak levels

> more precisely. I'd appreciate if Andy could comment on this.

I don't want to be stubborn about this, but I don't think taking a dose and

a half will make much of a difference. Two doses will. If you want, we can

do the math.

As I said, I have no idea if this would be an important matter or not.

Probably not, otherwise somebody would have said something by now.

Valentina