Re: I want to stop chemo for LDN

[Guest guest]

Ovgu, This is only my opinion, but if you can handle Rebif and Novantrone, LDN should be a piece of cake!!! If you are going to make your own with the liquid method, changing the doseage will not be a problem. I would start at 3 mg or 4.5 mg and see what happens. You can easily go up or down. I wish you the best! Marcie Övgu CEBÝR <ovgu@...> wrote: Hello friends, This is Ovgu from Istanbul Turkey. I am a secondary progressive 32 year old MS patient with disabilities. I have been reading messages for some time and very much interested in LDN and the miracles you guys have been experiencing. First time I heard about LDN was I guess in 2003 but at that time I was on Rebif 44. I wasn’t brave enough to stop Rebif and start LDN. By the time passed MS progressed. Now I can hardly walk 20 meters. I am using wheelchair. What doctors did was putting me on mitoxantrone in 2006. Mitoxantrone helped to keep my MS stable but possible side effects of this drug like leukemia, heart disease and infertility freaks me out. I decided to make a radical change. My doctor who is a professor of

metabolic disorders and nutrition tested my urine for heavy metal toxicity. They found excessive amount of lead, arsenic and mercury. He said that it was because of leaky gut. He changed my diet to paleolitic; Gluten, diary and soy free to heal intestines. I want to stop mitoxantrone and start LDN. Naltrexone is not sold in Turkey but a friend in Germany will buy it for me and I will make a liquid LDN at home. But now I need your help on the following. Has any of you stopped mitoxantrone (novantrone) and start LDN? What changes did you experience? I took mitoxantrone 2,5 months ago. How long do I have to wait to start LDN? What is the start dose1,5 – 3 or 4,5 ? Thank you very much in advance. Ovgu

[Guest guest]

Hi Marcie, I just read your reply to Ovgu???? I never heard of "making your own". HOW do you do it??? Barbara also, as a newbie here,,can you use it along w/ these other approaches on here??barbara

Re: [low dose naltrexone] I want to stop chemo for LDN

Ovgu,

This is only my opinion, but if you can handle Rebif and Novantrone, LDN should be a piece of cake!!! If you are going to make your own with the liquid method, changing the doseage will not be a problem. I would start at 3 mg or 4.5 mg and see what happens. You can easily go up or down.

I wish you the best!

Marcie

Övgu CEBÝR <ovgudogahuzurevi> wrote:

Hello friends,

This is Ovgu from Istanbul Turkey. I am a secondary progressive 32 year old MS patient with disabilities.

I have been reading messages for some time and very much interested in LDN and the miracles you guys have been experiencing.

First time I heard about LDN was I guess in 2003 but at that time I was on Rebif 44.

I wasn’t brave enough to stop Rebif and start LDN.

By the time passed MS progressed. Now I can hardly walk 20 meters. I am using wheelchair.

What doctors did was putting me on mitoxantrone in 2006. Mitoxantrone helped to keep my MS stable but possible side effects of this drug like leukemia, heart disease and infertility freaks me out.

I decided to make a radical change.

My doctor who is a professor of metabolic disorders and nutrition tested my urine for heavy metal toxicity. They found excessive amount of lead, arsenic and mercury. He said that it was because of leaky gut. He changed my diet to paleolitic; Gluten, diary and soy free to heal intestines.

I want to stop mitoxantrone and start LDN. Naltrexone is not sold in Turkey but a friend in Germany will buy it for me and I will make a liquid LDN at home.

But now I need your help on the following.

Has any of you stopped mitoxantrone (novantrone) and start LDN?

What changes did you experience?

I took mitoxantrone 2,5 months ago. How long do I have to wait to start LDN?

What is the start dose1,5 – 3 or 4,5 ?

Thank you very much in advance.

Ovgu

[Guest guest]

It is important to support glutathione when chelating. mjh

Welcome, Ovgu. We are honored to have you here.> My doctor who is a professor of metabolic disorders and nutritiontested my> urine for heavy metal toxicity. They found excessive amount of lead,arsenic> and mercury. There is a well-tolerated chelating agent which wasdesigned to help remove heavy metals from the body.It can be given orally, which is a great advantage.Many strong chelators must be given intravenously.The agent is dimercaptosuccinic acid, or DMSA.Many carefully reviewed studies have showed thesafety and effectiveness of DMSA therapy. There is aterm in medical English: "the standard of care". A therapy which is the standard of care is the best and safest available therapy for that condition.For heavy metal poisoning, DMSA is considered to be the standard of care. It is safe enough to be usedin small children without risk.DMSA is strongly specific to mercury. I had high bloodlevels of mercury, and also had dental work containingmercury amalgam. (I can not say whether the amalgamcaused the high blood levels. But I suspect that it did.)I used DMSA at the time the amalgams were removed frommy teeth. The new dental repairs are a non-metalliccomposite material.Urine tests were done to determine how much mercurywas coming out. There was a lot of it. I am now backwithin safe levels, measured by urine and blood tests.I can not speak to the connection (if any) betweenheavy metal poisoning and MS. I have no specificbackground in either one.What I will note is that if you draw two columns side by side on a piece of paper, and list MS symptoms in one column, and list heavy metal toxicity symptoms in the other column, there is much similarity.DMSA will also bind to arsenic and lead, and it willhelp those move out of the body, just as it does withmercury.However, DMSA binds with different strengths. It bindsmercury more rapidly and strongly. Until your bodyburden of mercury comes down, the arsenic and leadwill remain.Note also that DMSA is very efficient at getting heavymetals in your blood. It is less efficient at removingthose metals if the metals are in tissue. Much of yourbody burden of metals will be in tissue.If you get the metals out of the blood, some of the stored metals in the tissues will slowly migrate back out into the blood. A repeat chelation will get those.The question now is this: can you get DMSA in Turkey?DMSA is sold in the US as a prescription medicine. Trade names for it are "Succimer" or "Chemet". I have also seen DMSA sold without prescription in UShealth food stores and at chemical supply firms. This is the identical chemical, but may be of a lower grade,and might be less safe to consume.(The purity of chemicals which humans will consume isregulated by law in the US. For human use, purity mustbe high. The same chemical is sometimes sold at a less pure grade for animal or industrial use.)I am certain that DMSA is sold in the UK, and it isnow inexpensive to travel between Turkey and Britain,so perhaps a friend can bring some to you.This UK firm says that they sell DMSA. I do not knowhow pure it is. http://www.seeknatural.co.uk/product-109.htmlI strongly recommend careful testing both before andafter you take DMSA. You will want to know how muchmetal remains in your body. If your tests fall to alow level after several DMSA courses, that is a verygood sign.> What is the start dose1,5 - 3 or 4,5 ?I myself would use 4,5mg immediately. And would reduce the dose if 4,5 was too much to tolerate.Good luck to you as you search for better health.--Get a sneak peek of the all-new AOL.com.

[Guest guest]

Tis sounds like a smart doc. Your are fortunate. These metals are also an issue with autistic children and you might benefit further by reading the FILES in Autism_LDN group. mjh

Rather than starting chelation right away he prefers a softer way; hyperbaric oxygen therapy (HBOT) + paleolitic diet + detox bath with magnesium sulfate. He said he will start DMSA after another urine test. I will order DMSA via internet or from a pharmacy in Turkey which sell DMSA at a very high price. Get a sneak peek of the all-new AOL.com.

[Guest guest]

>

> Hi Marcie, I just read your reply to Ovgu???? I never heard of

" making your own " . HOW do you do it??? Barbara also, as a newbie

here,,can you use it along w/ these other approaches on here??barbara

I believe that what Marcie was referring to when she

said " making your own " was the practice of obtaining

naltrexone in the large 50mg tablets, then crushing

and dissolving them in 50ml of distilled water.

This gives a liquid preparation (which should be kept

sealed and refrigerated) at 1mg/ml concentration. The

dose can be measured out with a calibrated dropper.

Those who do not want to do this must have a competent

compounding pharmacy make up LDN for them. Note that

the stability of solid LDN in capsules is probably

going to be better than for LDN dissolved in water.

You will unavoidably lose a small amount of the aqueous

LDN due to oxidation. Thus, do not make up large batches.

Make up only one 50ml amount at at time, using only one

50mg pill. Then make more when you need it.

--

[Guest guest]

>

> Hi Marcie, I just read your reply to Ovgu???? I never heard

of " making your own " . HOW do you do it??? Barbara

========

Sometimes people cannot get their docs to prescribe LDN so they

purchase the 50mg Naltrexone tablets from an online pharmacy and

usually the medication coe from a foreign country like India, etc.

Homemade LDN from the 50mg Naltrexone tablets

Liquid LDN (Easiest): Acquire some ml measuring equipment from the

baby section of a Drug Store and a small bottle with a screw-on cap.

Put 50ml of water (distilled is best) and one 50mg " ReVia " Naltrexone

tablet in the small bottle and let it dissolve with a little time and

shaking. Now each ml of water in that small bottle contains 1 mg of

Naltrexone. At bedtime shake the bottle, take a desired dose (no more

than 4.5ml), chase it down with some water and store the small bottle

in the refrigerator. Some people have reported splitting the tablet in

half and dissolving it in 25ml of water to assure freshness every week.

[Guest guest]

>

> Hello friends,

>

> This is Ovgu from Istanbul Turkey. I am a secondary progressive 32

year old

> MS patient with disabilities.

>

Welcome, Ovgu. We are honored to have you here.

> My doctor who is a professor of metabolic disorders and nutrition

tested my

> urine for heavy metal toxicity. They found excessive amount of lead,

arsenic

> and mercury.

There is a well-tolerated chelating agent which was

designed to help remove heavy metals from the body.

It can be given orally, which is a great advantage.

Many strong chelators must be given intravenously.

The agent is dimercaptosuccinic acid, or DMSA.

Many carefully reviewed studies have showed the

safety and effectiveness of DMSA therapy. There is a

term in medical English: " the standard of care " .

A therapy which is the standard of care is the best

and safest available therapy for that condition.

For heavy metal poisoning, DMSA is considered to be

the standard of care. It is safe enough to be used

in small children without risk.

DMSA is strongly specific to mercury. I had high blood

levels of mercury, and also had dental work containing

mercury amalgam. (I can not say whether the amalgam

caused the high blood levels. But I suspect that it did.)

I used DMSA at the time the amalgams were removed from

my teeth. The new dental repairs are a non-metallic

composite material.

Urine tests were done to determine how much mercury

was coming out. There was a lot of it. I am now back

within safe levels, measured by urine and blood tests.

I can not speak to the connection (if any) between

heavy metal poisoning and MS. I have no specific

background in either one.

What I will note is that if you draw two columns side

by side on a piece of paper, and list MS symptoms in

one column, and list heavy metal toxicity symptoms in

the other column, there is much similarity.

DMSA will also bind to arsenic and lead, and it will

help those move out of the body, just as it does with

mercury.

However, DMSA binds with different strengths. It binds

mercury more rapidly and strongly. Until your body

burden of mercury comes down, the arsenic and lead

will remain.

Note also that DMSA is very efficient at getting heavy

metals in your blood. It is less efficient at removing

those metals if the metals are in tissue. Much of your

body burden of metals will be in tissue.

If you get the metals out of the blood, some of the

stored metals in the tissues will slowly migrate back

out into the blood. A repeat chelation will get those.

The question now is this: can you get DMSA in Turkey?

DMSA is sold in the US as a prescription medicine.

Trade names for it are " Succimer " or " Chemet " .

I have also seen DMSA sold without prescription in US

health food stores and at chemical supply firms. This

is the identical chemical, but may be of a lower grade,

and might be less safe to consume.

(The purity of chemicals which humans will consume is

regulated by law in the US. For human use, purity must

be high. The same chemical is sometimes sold at a less

pure grade for animal or industrial use.)

I am certain that DMSA is sold in the UK, and it is

now inexpensive to travel between Turkey and Britain,

so perhaps a friend can bring some to you.

This UK firm says that they sell DMSA. I do not know

how pure it is.

http://www.seeknatural.co.uk/product-109.html

I strongly recommend careful testing both before and

after you take DMSA. You will want to know how much

metal remains in your body. If your tests fall to a

low level after several DMSA courses, that is a very

good sign.

> What is the start dose1,5 - 3 or 4,5 ?

I myself would use 4,5mg immediately. And would reduce

the dose if 4,5 was too much to tolerate.

Good luck to you as you search for better health.

--

[Guest guest]

I’d like to thank everyone for replies.

My urine was tested in US at a company

called doctors data. So we had to mail my urine to USAJ

It was a specific test called DMSA provoked

urine test for which I had to take 18 capsules of DMSA at a time and collected

urine in 6 hours.

It is done in this way since for people

with leaky gut heavy metal is not found in blood it is kept in organs such as

brain!, liver and bones.

Heavy metals are neuro toxic and also

cause cancer as we all know. I am not sure if it causes MS either but I am sure

that it is bad for CNS.

Cure Explorer, thanks for your warm

welcome and you are right about DMSA chelation therapy. My doc thinks that

starting DMSA kind of chelation might trigger symptoms now since a lot of heavy

metal comes out of liver and cause reexposure. I mean that body can be exposed

by too much heavy metals than it can get rid of in a short time. Of course if

you keep chelation all of them will eventually leave your body.

Rather than starting chelation right away

he prefers a softer way; hyperbaric oxygen therapy (HBOT) + paleolitic diet +

detox bath with magnesium sulfate. He said he will start DMSA after another urine

test. I will order DMSA via internet or from a pharmacy in Turkey which sell

DMSA at a very high price.

I’d like to give an important information to

all MS people; I met another doc in Turkey who treats autistic children with HBOT

+ paleolitic diet. Autistuc children also have heavy metal burden. He says that

people with degenerative neurologic diseases like autism and MS have opioid

instability and that’s whay he suggests the diet. When I read this info I

remembered LDN which is an oipoid antogist. I thought maybe that’s why LDN

worked for MS and started searching the net again.

Now it is time for me to get

responsibility of my own health from the hand of neurologists. I waited so

long, for 9 years to get help from neurologists.

I am committed this time. I will at least

stop progression of MS no matter what the neurologists say.

Maybe you guys might be interested in

heavy metal testing. I strongly suggest.

It was kind of long,

sorry about spellingJ

Love,

Ovgu

From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of cure_explorer

Sent: Monday, July 30, 2007 12:29

AM

low dose naltrexone

Subject: [low dose naltrexone] Re: I

want to stop chemo for LDN

>

> Hello friends,

>

> This is Ovgu from Istanbul Turkey. I am a secondary progressive 32

year old

> MS patient with disabilities.

>

Welcome, Ovgu. We are honored to have you here.

> My doctor who is a professor of metabolic disorders and nutrition

tested my

> urine for heavy metal toxicity. They found excessive amount of lead,

arsenic

> and mercury.

There is a well-tolerated chelating agent which was

designed to help remove heavy metals from the body.

It can be given orally, which is a great advantage.

Many strong chelators must be given intravenously.

The agent is dimercaptosuccinic acid, or DMSA.

Many carefully reviewed studies have showed the

safety and effectiveness of DMSA therapy. There is a

term in medical English: " the standard of care " .

A therapy which is the standard of care is the best

and safest available therapy for that condition.

For heavy metal poisoning, DMSA is considered to be

the standard of care. It is safe enough to be used

in small children without risk.

DMSA is strongly specific to mercury. I had high blood

levels of mercury, and also had dental work containing

mercury amalgam. (I can not say whether the amalgam

caused the high blood levels. But I suspect that it did.)

I used DMSA at the time the amalgams were removed from

my teeth. The new dental repairs are a non-metallic

composite material.

Urine tests were done to determine how much mercury

was coming out. There was a lot of it. I am now back

within safe levels, measured by urine and blood tests.

I can not speak to the connection (if any) between

heavy metal poisoning and MS. I have no specific

background in either one.

What I will note is that if you draw two columns side

by side on a piece of paper, and list MS symptoms in

one column, and list heavy metal toxicity symptoms in

the other column, there is much similarity.

DMSA will also bind to arsenic and lead, and it will

help those move out of the body, just as it does with

mercury.

However, DMSA binds with different strengths. It binds

mercury more rapidly and strongly. Until your body

burden of mercury comes down, the arsenic and lead

will remain.

Note also that DMSA is very efficient at getting heavy

metals in your blood. It is less efficient at removing

those metals if the metals are in tissue. Much of your

body burden of metals will be in tissue.

If you get the metals out of the blood, some of the

stored metals in the tissues will slowly migrate back

out into the blood. A repeat chelation will get those.

The question now is this: can you get DMSA in Turkey?

DMSA is sold in the US as a prescription medicine.

Trade names for it are " Succimer " or " Chemet " .

I have also seen DMSA sold without prescription in US

health food stores and at chemical supply firms. This

is the identical chemical, but may be of a lower grade,

and might be less safe to consume.

(The purity of chemicals which humans will consume is

regulated by law in the US. For human use, purity must

be high. The same chemical is sometimes sold at a less

pure grade for animal or industrial use.)

I am certain that DMSA is sold in the UK, and it is

now inexpensive to travel between Turkey and Britain,

so perhaps a friend can bring some to you.

This UK firm says that they sell DMSA. I do not know

how pure it is.

http://www.seeknatural.co.uk/product-109.html

I strongly recommend careful testing both before and

after you take DMSA. You will want to know how much

metal remains in your body. If your tests fall to a

low level after several DMSA courses, that is a very

good sign.

> What is the start dose1,5 - 3 or 4,5 ?

I myself would use 4,5mg immediately. And would reduce

the dose if 4,5 was too much to tolerate.

Good luck to you as you search for better health.

--