A cross-over study of the effect of a single oral feeding of medium chain triglyceride oil vs. canola oil on post-ingestion plasma triglyceride levels in healthy men.

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Hi All,

Here we see that post meal, olive oil resulted in an elevation of triglycerides

(three molecules of fatty acids linked

to a glycerol molecule) in the blood, while the use of a oil rich in medium

chain fatty acids (MCT) resulted in a

decrease in post meal triglycerides.

Elevated levels of peroxidized (attacked by free radicals) triglycerides are now

accepted as an independent risk factor

for heart and blood vessel disease. Remember than only mono and poly fatty

acids can be attacked and peroxidized by

free radicals. Saturated fats are stable and can't be altered to harmful forms.

Other studies suggest a MCT rich meal actually increases fatty acid oxidation

and thus should explain why triglycerides

levels fell after the MCT rich meal as the MCT has turned up the " Burn fat

furnace " .

Add in that olive oil contains double bonds which can be peroxidized (attacked

by free radicals) and thus may elevate

blood vessel plaque formation and you just gotta ask ...

Extra Virgin Olive Oil on that next salad or please pass the MCT rich

Virgin Coconut Oil?

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=9\

988780 & dopt=Abstract

Altern Med Rev 1999 Feb;4(1):23-8 Related Articles, LinkOut, Books

A cross-over study of the effect of a single oral feeding of medium chain

triglyceride oil vs. canola oil on

post-ingestion plasma triglyceride levels in healthy men.

Calabrese C, Myer S, Munson S, Turet P, Birdsall TC.

Bastyr University Research Institute, 14500 ita Dr. NE, Kenmore, WA 98028,

USA. carlo@...

Due to its unique absorption and metabolism characteristics, medium chain

triglyceride (MCT) oil, consisting of fatty

acids with 8-12 carbons, has been used therapeutically since the 1950s in the

treatment of fat malabsorption, cystic

fibrosis, epilepsy, weight control, and to increase exercise performance.

Medium chain triglycerides are easily hydrolyzed in the intestines and the fatty

acids are transported directly to the

liver via the portal venous system, in contrast to long-chain fatty acids

(LCFAs), which are incorporated into

chylomicrons for transport through the lymphatic system or peripheral

circulation.

Medium chain fatty acids (MCFAs) do not require carnitine to cross the double

mitochondrial membrane of the hepatocyte,

thus they quickly enter the mitochondria and undergo rapid beta-oxidation,

whereas most LCFAs are packaged into

triglycerides in the hepatocyte.

In this single-blind, randomized, cross-over study, 20 healthy men ingested a

single dose of either 71 g of MCT oil or

canola oil.

Blood samples were taken at baseline and at hours one through five

post-ingestion to compare the effect of a single oral

dosing of MCT oil versus canola oil on post-ingestion plasma triglyceride

levels.

Mean triglyceride values after canola oil increased 47 percent above baseline (p

<0.001), while mean triglyceride values

after MCT oil decreased 15 percent from baseline (p `0.001), which is consistent

with several other studies involving

short- and longer-term feeding with MCT oil.

The effect of long-term usage of MCT oil on triglycerides is yet to be

established.

PMID: 9988780 [PubMed - indexed for MEDLINE]

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Good Health & Long Life,

Greg , gowatson@...

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