vit e

[Guest guest]

I take some but have to be careful because I am an easy bleeder which is

probably the main thing to watch out for.

Are you getting in other oils (Flax, salmon, borage or black currant)?

Is it helping?

KM

mcpherson.bg@... wrote:

I know Dr. D says that we O's shouldn't take Vitamin E, but do some of you

anyway? I stopped taking it for a year or two, but now I am trying it again,

mostly trying to reduce menopausal symptoms.

Gretchen

[Guest guest]

Upon Irene's advice i started taking Vitamin E for some scars. I take 800 UI's

per day. I also take Wild Fish Oil capsules. Have to take those with food

otherwise I end up with a constant fishy taste in my mouth (ewww).

kathy matthews <kathymatthews@...> wrote:I take some but have to be

careful because I am an easy bleeder which is probably the main thing to watch

out for.

Are you getting in other oils (Flax, salmon, borage or black currant)?

Is it helping?

KM

mcpherson.bg@... wrote:

I know Dr. D says that we O's shouldn't take Vitamin E, but do some of you

anyway? I stopped taking it for a year or two, but now I am trying it again,

mostly trying to reduce menopausal symptoms.

Gretchen

[Guest guest]

Most supplements, especially oils should always be taken with food for proper

digestion and absorption.

Just watch for easy bleeding and slow clotting.

monika <monika_vidas@...> wrote:

Upon Irene's advice i started taking Vitamin E for some scars. I take 800 UI's

per day. I also take Wild Fish Oil capsules. Have to take those with food

otherwise I end up with a constant fishy taste in my mouth (ewww).

__________________________________________________

[Guest guest]

mcpherson.bg@... wrote:

> I know Dr. D says that we O's shouldn't take Vitamin E, but do some of you

anyway?

Hi Gretchen,

I take 1000 IU per day, have doen for several years and if I do not I

know the difference within 2 days. To not take it is nuts. And not

walnuts :-)

I do not agree with Dr D there!!!

Vit E is an esential nutrient, a great antioxidant, it detoxes the

environmental toxins we breathe in daily, and any oil soluble toxins we

ingest - it keeps skin supple, improves metabolism and cell wall

flexibility to allow food in and roxins out and undoes scarring such as

kidney damage - to list a tip of the iceberg number of benefits. It

would take a book to list them all :-)

In my case it also lowers cortisol level.

Not for 2 split-seconds would I believe it is negative to take it.

:-))

Namaste,

Irene

--

Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

I read that Vit. E will heal spider veins on your skin & face. I don't

know how much you need to take for that.

I add a couple capsules of vit. E to any new bottle of cooking oil I

open as a natural preservative.

- T

> I know Dr. D says that we O's shouldn't take Vitamin E, but do some

of you anyway? I stopped taking it for a year or two, but now I am

trying it again, mostly trying to reduce menopausal symptoms.

>

> Gretchen

>

[Guest guest]

What brand of vit. E do you reccomend?

Do you think it helps with spider veins and varicose veins?

Thanks, T

> > I know Dr. D says that we O's shouldn't take Vitamin E, but do

some of you anyway?

>

> Hi Gretchen,

> I take 1000 IU per day, have doen for several years and if I do not I

> know the difference within 2 days. To not take it is nuts. And not

> walnuts :-)

> I do not agree with Dr D there!!!

> Vit E is an esential nutrient, a great antioxidant, it detoxes the

> environmental toxins we breathe in daily, and any oil soluble toxins we

> ingest - it keeps skin supple, improves metabolism and cell wall

> flexibility to allow food in and roxins out and undoes scarring such as

> kidney damage - to list a tip of the iceberg number of benefits. It

> would take a book to list them all :-)

>

> In my case it also lowers cortisol level.

>

> Not for 2 split-seconds would I believe it is negative to take it.

> :-))

>

> Namaste,

> Irene

> --

> Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

> www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

> Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

I'd be interested in knowing how much you'd have to take (or how long it would

take) to see improvement in that.

I can say that my stretch marks have started to fade since taking the Vit. E.

Tamara <tamaratornado@...> wrote:

I read that Vit. E will heal spider veins on your skin & face. I don't

know how much you need to take for that.

I add a couple capsules of vit. E to any new bottle of cooking oil I

open as a natural preservative.

- T

> I know Dr. D says that we O's shouldn't take Vitamin E, but do some

of you anyway? I stopped taking it for a year or two, but now I am

trying it again, mostly trying to reduce menopausal symptoms.

>

> Gretchen

>

[Guest guest]

I know that last year when I was having all those problems with that

pregnancy, my midwife put me on 800IU's of vit. E per day. 400 at a

time. I don't recall any negative reaction to it.

I did bleed for 7 1/2 weeks miscarrying but it didn't have anything to

do with the vit. E. Because I can still take it and I'm fine. I

don't bleed any more than normal. If anything, my bleeding on my

periods have been below normal since I had this last miscarriage.

My midwife had me take vit E because it's a uterin strengthener. She

said taking 800 IU's per day would not hurt.

I also use it on my skin very regularly. I don't use any skin creams.

Your skin is the largest organ of your body - so I'm told. So I'm

very cautious at what I put on my skin. I have found that Vit. E will

clear up acne in a heartbeat! I love it! I always put it on at night

otherwise people would look at you strange with a wet, shiny, sticky face!

Leanne!

[Guest guest]

Make sure it is natural Vit E from a good company

d-(alpha,gamma..etc..) tocopherol is natural

the dl--- form is synthetic.

Tamara <tamaratornado@...> wrote:

What brand of vit. E do you reccomend?

Do you think it helps with spider veins and varicose veins?

Thanks, T

> > I know Dr. D says that we O's shouldn't take Vitamin E, but do

some of you anyway?

>

> Hi Gretchen,

> I take 1000 IU per day, have doen for several years and if I do not I

> know the difference within 2 days. To not take it is nuts. And not

> walnuts :-)

> I do not agree with Dr D there!!!

> Vit E is an esential nutrient, a great antioxidant, it detoxes the

> environmental toxins we breathe in daily, and any oil soluble toxins we

> ingest - it keeps skin supple, improves metabolism and cell wall

> flexibility to allow food in and roxins out and undoes scarring such as

> kidney damage - to list a tip of the iceberg number of benefits. It

> would take a book to list them all :-)

>

> In my case it also lowers cortisol level.

>

> Not for 2 split-seconds would I believe it is negative to take it.

> :-))

>

> Namaste,

> Irene

> --

> Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

> www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

> Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

In a message dated 4/29/2005 12:35:58 PM Eastern Daylight Time,

monika_vidas@... writes:

I can say that my stretch marks have started to fade since taking the Vit. E.

How much do you take on a daily basis and how long did it take before you

noticed a difference?

[Guest guest]

Maddviking@... wrote: (re stretch marks)

> How much do you take on a daily basis and how long did it take before you

> noticed a difference?

>

I'd be intereted too. I take 1000 IU a day and beause of that I failed

to develop stretch marks that are normal in Cushing's syndrome. In fact

one doctor says it can not be cushings, as if it was, I would have

stretch marks. The blood readings for cushings are apparerently not

relevant to this guy - he wants to *see* stretch marks :-))

I suppose I could suggest he inject 320 units a day of cortisol and

see what *his* stretch marks look like :-)

He might go buy Vit E after all :-)) I had been taking it for my

enlarged heart problem (now normal size heart).

....Irene

--

Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

I was contemplating applying it topically and seeing what happens ...

Irene de Villiers <furryboots@...> wrote:

Maddviking@... wrote: (re stretch marks)

> How much do you take on a daily basis and how long did it take before you

> noticed a difference?

>

I'd be intereted too. I take 1000 IU a day and beause of that I failed

to develop stretch marks that are normal in Cushing's syndrome. In fact

one doctor says it can not be cushings, as if it was, I would have

stretch marks. The blood readings for cushings are apparerently not

relevant to this guy - he wants to *see* stretch marks :-))

I suppose I could suggest he inject 320 units a day of cortisol and

see what *his* stretch marks look like :-)

He might go buy Vit E after all :-)) I had been taking it for my

enlarged heart problem (now normal size heart).

....Irene

--

Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

monika wrote:

> I was contemplating applying it topically and seeing what happens ...

Accoreding to Adelle that works fine :-)

.....Irene

--

Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

Irene, in response to this (old) post from you: what is the difference you

notice if you fail to take vitamin E?

--Gretchen

----- Original Message -----

From: Irene de Villiers

Sent: Thursday, April 28, 2005 6:40 PM

mcpherson.bg@... wrote:

> I know Dr. D says that we O's shouldn't take Vitamin E, but do some of you

anyway?

Hi Gretchen,

I take 1000 IU per day, have doen for several years and if I do not I know the

difference within 2 days. To not take it is nuts. And not walnuts :-) I do not

agree with Dr D there!!!

Vit E is an esential nutrient, a great antioxidant, it detoxes the

environmental toxins we breathe in daily, and any oil soluble toxins we ingest

- it keeps skin supple, improves metabolism and cell wall flexibility to allow

food in and roxins out and undoes scarring such as kidney damage - to list a tip

of the iceberg number of benefits. It would take a book to list them all :-)

In my case it also lowers cortisol level.

Not for 2 split-seconds would I believe it is negative to take it.

:-))

Namaste,

Irene

[Guest guest]

mcpherson.bg@... wrote:

> Irene, in response to this (old) post from you: what is the difference you

notice if you fail to take vitamin E?

> --Gretchen

High cortisol levels and the damage that causes; high blood pressure;

less cell healing; more edema; more toxicity in general; shortness of

breath; stretch marks, dry skin; worse lipid profiles; kidney stress;

heart palpitations; etc etc ....

A very long list of things. Vit E is the body's universal cell wall

healer and antioxidant - removes scar tissue so it can be replaced with

healthy tissue.

In MY case it counters stress hormone of which I have too much.

Namaste,

Irene

--

Irene de Villiers, B.Sc AASCA MCSSA D.I.Hom. Box 4703 Spokane WA 99220.

www.angelfire.com/fl/furryboots/clickhere.html (Veterinary Homeopath.)

Proverb:Man who say it cannot be done should not interrupt one doing it.

[Guest guest]

Dr usman recommneds this stuff - looks good, haven't tried it yet

http://www.yasoo.com/aqua-e.htm

Aqua-E4 and 8 oz. Bottles

Yasoo Health, the world's leading authority in vitamin E research and formulation, introduces Aqua-E, a new water soluble complete vitamin E with tocopherols and tocotrienols. This unique patented supplement is specially formulated under cGMP and is now available. Aqua-E is specially formulated for enhanced absorption. It was designed to help meet the needs of people who have difficulty absorbing vitamin E due to diseases associated with malabsorption such as cholestasis, cystic fibrosis, Crohn's and ulcerative colitis (IBD), alcoholic hepatitis, other liver diseases, and AIDS. It is important to note that malabsorption also occurs in the elderly and with other serious disease conditions and with some drug therapies. Please see our Aqua-E Advantage Section for more details.

Free of animal products, yeast, wheat, added colors or flavors, sweeteners, and salt. Suitable for use by vegetarians.

[Guest guest]

Mandi is this sourced from Soy, I am trying to find one aswell, but not from natural soy oil, synthetic would be fine.

Vicky

xx

[Guest guest]

Hi Vicky,

I know that Terry from Brainchild Nutritionals often visits this

message board so maybe she can clarify this further. I remember

Lang recommending to stay away from synthetic vitamins. My son

is allergic to soy so I do have the same problem. Right now, we are

giving a small dose of soy-based vitamin E which he seems to tolerate,

but I am also watching.

Not that I want to add any confusion, but I thought I should mention

this anyway.

>

> I ordered Kirkmans Vit E on the basis it's synthetic as most seem to be

> derived from Soy, anyway it's early days but appears to be

> reacting to it, is it possible if a synthetic vitamin is close enough

> to the normal source then a reaction is still possible?

> TIA

> Vicky

>

[Guest guest]

We feel very strongly that our kids really need natural vitamin E, not

synthetic. Here's some information I found about natural vs.

synthetic (this is from Carlson's website). Natural Vitamin E comes

from rice, corn and soy sources. We have spoken personally with

several of the chemists who formulate our natural vitamin E, and they

tell us that under chemical analysis, vitamin E made from one source

(say, rice) is indistinguishable from that made from other sources (like

corn or soy). This means that all the rice, corn or soy protein is

completely removed in the process of making the vitamin E, and therefore

allergy reactions (which are to proteins) should not occur.

We buy the best natural vitamin E available. It's made in Germany

and costs a lot. I don't know if some of the cheaper ones might

still have protein in them. I also have no idea what is in the

synthetic vitamin E, so don't know about allergies to that. Some

synthetic vitamins are made from petrochemicals. I do know that

is vehement in his preference for natural vitamin E over

synthetic, even in kids as sensitive as his.

Here's that info:

-------------------------------------------------------------

Natural vitamin E is the single molecular configuration that occurs in

nature. Synthetic vitamin E is a mixture of 8 molecular configurations, 7

of which occur when made by man.

Dr. Graham Burton, associated with the National Research Council of

Canada, studied the body's response to natural vitamin E compared to

synthetic vitamin E. The study strongly indicates your body prefers

natural vitamin E, showing that it is retained in your body many times

longer than the synthetic vitamin E, with specific results showing:

5.3 times more natural vitamin E in the brain. .6 times more natural vitamin E in red blood cells. 2.6 times more natural vitamin E in the lungs. 2.4 times more natural vitamin E in the plasma 1.9 times more natural vitamin E in the heart 1.7 times more natural vitamin E in the muscles.

Why does your body prefer natural vitamin E? Research scientist

Maret Traber's work indicates that the liver preferentially recycles the

natural form of vitamin E (d-alpha tocopherol), causing the excretion of

synthetic forms of other tocopherols.

Some researchers have questioned whether special configurations of

tocopherol found only in synthetic vitamin E are actually a hindrance to

the body because they tie up receptor sites, stopping the naturally

occurring form of vitamin E from acting.

-------------------------------------

Here's another reference that was very informative in case you want to

get more technical:

http://www.cognis-us.com/framescout.html?/cognis/nutritionandhealth/private/productinformation/research/natsynth.htm

Terri at Brainchild

At 08:27 AM 12/13/2005, you wrote:

Hi Vicky,

I know that Terry from Brainchild Nutritionals often visits this

message board so maybe she can clarify this further. I remember

Lang recommending to stay away from synthetic vitamins. My

son

is allergic to soy so I do have the same problem. Right now, we are

giving a small dose of soy-based vitamin E which he seems to

tolerate,

but I am also watching.

Not that I want to add any confusion, but I thought I should mention

this anyway.

>

> I ordered Kirkmans Vit E on the basis it's synthetic as most seem to

be

> derived from Soy, anyway it's early days but appears to be

> reacting to it, is it possible if a synthetic vitamin is close

enough

> to the normal source then a reaction is still possible?

> TIA

> Vicky

>

[Guest guest]

I give Mark (who is 13) 400 iu in the morning and another 400 iu in the late

afternoon for optimal performance. I know that there are a lot of people giving

out much higher doses with kids who are a lot younger.

I notice good things with the vitamin E. Clearer speech, clearer thought and

better attention are a few items that I see with an older kid. The moms with

younger kids are often seeing a lot 'more' leaps in development particularly in

speech and sensory interests.

Janice

[sPAM][ ] Vit E

For those of you giving extra vit E, how much are you giving? My son

has a compounded multi-vit prescribed by Dr. Jepson at Thoughtful

House and it has 200 iu's of vit E. Not sure what would be considered

overdoing it to the point of toxic if I supplemented more? Anyone

know? Also, in our NN CLO, it says it has vit E in it. So confused

on how much to give and how much is too much. HELP!

Carla

[Guest guest]

I started my son (35 mo) on Omega Complete a week ago. Am I supposed

to give him Vit E too? If so, how much? If I read the archive

correctly, I keep him on 1 Omega complete until he plateaus and then

increase to 2?

Thanks, Janet

[Guest guest]

fyi on vitamin e    source nih.gov

 

 

Table 1: Selected Food Sources of Vitamin E [4]

FOOD

Milligrams (mg)

Alpha-tocopherol

per serving

Percent

DV*

Wheat germ oil, 1 tablespoon

20.3

100

Almonds, dry roasted, 1 ounce

7.4

40

Sunflower seed kernels, dry roasted, 1 ounce

6.0

30

Sunflower oil, over 60% linoleic, 1 tablespoon

5.6

30

Safflower oil, over 70% oleic, 1 tablespoon

4.6

25

Hazelnuts, dry roasted, 1 ounce

4.3

20

Peanut butter, smooth style, vitamin and mineral fortified, 2 Tablespoons

4.2

20

Peanuts, dry roasted, 1 oz

2.2

10

Corn oil (salad or vegetable oil), 1 tablespoon

1.9

10

Spinach, frozen, chopped, boiled, ½ cup

1.6

6

Broccoli, frozen, chopped, boiled, ½ cup

1.2

6

Soybean oil, 1 tablespoon

1.3

6

Kiwi, 1 medium fruit without skin

1.1

6

Mango, raw, without refuse, ½ cup sliced

0.9

6

Spinach, raw, 1 cup

0.6

4*DV = Daily Value. DVs are reference numbers developed by the Food and Drug

Administration (FDA) to help consumers determine if a food contains a lot or a

little of a specific nutrient. The DV for vitamin E is 30 International Units

(or about 20 mg alpha-tocopherol). Most food labels do not list a food's vitamin

E content. The percent DV (%DV) listed on the table indicates the percentage of

the DV provided in one serving. A food providing 5% of the DV or less is a low

source while a food that provides 10-19% of the DV is a good source. A food that

provides 20% or more of the DV is high in that nutrient. It is important to

remember that foods that provide lower percentages of the DV also contribute to

a healthful diet. For foods not listed in this table, please refer to the U.S.

Department of Agriculture's Nutrient Database Web site:

http://www.nal.usda.gov/fnic/foodcomp/search/.

What is the recommended intake for vitamin E?Recommendations for vitamin E are

provided in the Dietary Reference Intakes developed by the Institute of Medicine

[5]. Dietary Reference Intakes (DRIs) is the general term for a set of reference

values used for planning and assessing nutrient intake for healthy people. Three

important types of reference values included in the DRIs are Recommended Dietary

Allowances (RDA), Adequate Intakes (AI), and Tolerable Upper Intake Levels (UL).

The RDA recommends the average daily dietary intake level that is sufficient to

meet the nutrient requirements of nearly all (97-98%) healthy individuals in

each age and gender group [5]. An AI is set when there is insufficient

scientific data available to establish a RDA. AIs meet or exceed the amount

needed to maintain a nutritional state of adequacy in nearly all members of a

specific age and gender group. The UL, on the other hand, is the maximum daily

intake unlikely to

result in adverse health effects [5].

In Table 2, RDAs for vitamin E are based only on the alpha-tocopherol form of

vitamin E [5]. Table 2 also lists RDAs for vitamin E in International Units (IU)

because food and most supplement labels list vitamin E content in International

Units (1 mg alpha-tocopherol vitamin E = 1.49 IU).

Table 2: Recommended Dietary Allowances for Vitamin E for Children and Adults

[5]

Age

(years)

Children

(mg/day)

Men

(mg/day)

Women

(mg/day)

Pregnancy

(mg/day)

Lactation

(mg/day)

1-3

6 mg

(=9 IU)

4-8

7 mg

(=10.5 IU)

9-13

11 mg

(=16.5 IU)

11 mg

(=16.5 IU)

15 mg

(=22.5 IU)

19 mg

(=28.5 IU)

14 +

15 mg

(=22.5 IU)

15 mg

(=22.5 IU)

15 mg

(=22.5 IU)

19 mg

(=28.5 IU)

There is insufficient scientific data on vitamin E to establish an RDA for

infants. An Adequate Intake (AI) has been established that is based on the

amount of vitamin E consumed by healthy infants who are fed breast milk. Table 2

lists the adequate intakes for vitamin E for infants in mg alpha-tocopherol and

IUs (1 mg alpha-tocopherol = 1.49 IU) [5].

Table 3: Adequate Intake for Vitamin E for Infants [5]

Age

(months)

Males and Females

(mg/day)

0 to 6

4 mg

(=6 IU)

7 to 12

5 mg

(=7.5 IU)

Results of two national surveys, the National Health and Nutrition Examination

Results of two national surveys, the National Health and Nutrition Examination

Survey (NHANES III 1988-94) [6] and the Continuing Survey of Food Intakes by

Individuals (1994-96 CSFII) [7] indicated that diets of most Americans do not

provide the recommended intake for vitamin E. However, an Institute of Medicine

(IOM) report on vitamin E published in 2000 states that intake estimates of

vitamin E may be low because energy and fat intake are often underreported in

national surveys and because the kind and amount of fat added during cooking is

often not known. The IOM states that most North American adults get enough

vitamin E from their normal diets to meet current recommendations. However, they

do caution that low fat diets can result in a significant decrease in vitamin E

intake. " Low-fat diets can substantially decrease vitamin E intakes if food

choices are not carefully

made to enhance á-tocopherol intakes " [5].

Who is at risk for vitamin E deficiency?Vitamin E deficiency is rare in humans.

There are three specific situations when a vitamin E deficiency is likely to

occur.

persons who cannot absorb dietary fat due to an inability to secrete bile or

with rare disorders of fat metabolism are at risk of vitamin E deficiency [8];

individuals with rare genetic abnormalities in the alpha-tocopherol transfer

protein are at risk of vitamin E deficiency [9]; and

premature, very low birth weight infants (birth weights less than 1500 grams, or

3 pounds, 4 ounces) are at risk of vitamin E deficiency [3,10].Blood levels of

vitamin E may also be decreased with zinc deficiency [11]. Vitamin E deficiency

is usually characterized by neurological problems associated with nerve

degeneration in hands and feet [5]. These symptoms are also associated with

other medical conditions. A physician can determine if they are the result of a

vitamin E deficiency or are from another cause.

Who may need extra vitamin E to prevent a deficiency?Individuals who cannot

absorb fat require a vitamin E supplement because some dietary fat is needed for

the absorption of vitamin E from the gastrointestinal tract. Intestinal

disorders that often result in malabsorption of vitamin E and may require

vitamin E supplementation include [3]:

Crohn's Disease is an inflammatory bowel disease that affects the small

intestines. People with Crohn's disease often experience diarrhea and nutrient

malabsorption.

Cystic Fibrosis is an inherited disease that affects the lungs, gastrointestinal

tract, pancreas, and liver. Cystic fibrosis can interfere with normal digestion

and absorption of nutrients, especially of fat soluble vitamins including

vitamin E.People who cannot absorb fat often pass greasy stools or have chronic

diarrhea. People with an inability to secrete bile, a substance that helps fat

digestion, may need a special water-soluble form of vitamin E.

Abetalipoproteinemia is a rare inherited disorder of fat metabolism that results

in poor absorption of dietary fat and vitamin E [8]. The vitamin E deficiency

associated with this disease causes problems such as poor transmission of nerve

impulses, muscle weakness, and degeneration of the retina that can cause

blindness. Individuals with abetalipoproteinemia may be prescribed special

vitamin E supplements by a physician to treat this disorder [12].

Ataxia and vitamin E deficiency (AVED) is also a rare inherited disorder. It is

caused by a genetic defect in a liver protein that is responsible for

maintaining normal alpha-tocopherol concentrations in the blood. These

individuals have such severe vitamin E deficiency that without supplements they

are unable to walk (ataxia) [9].

Very low birth weight infants may be deficient in vitamin E [3,10]. Necrotizing

enterocolitits, a condition sometimes seen in very low birth weight infants that

is characterized by inflammation of the lining of the intestines, may lead to a

vitamin E deficiency [4]. These infants are usually under the care of a

neonatologist, a pediatrician specializing in the care of newborns who evaluates

and treats the exact nutritional needs of premature infants.

What are some current issues and controversies about vitamin E?Vitamin E and

heart disease

Preliminary research has led to a widely held belief that vitamin E may help

prevent or delay coronary heart disease [13]. Researchers have reported that

oxidative changes to LDL-cholesterol (sometimes called " bad " cholesterol)

promote blockages (atherosclerosis) in coronary arteries that may lead to heart

attacks. Vitamin E may help prevent or delay coronary heart disease by limiting

the oxidation of LDL-cholesterol [14]. Vitamin E also may help prevent the

formation of blood clots, which could lead to a heart attack. Observational

studies have associated lower rates of heart disease with higher vitamin E

intake. A study of approximately 90,000 nurses suggested that the incidence of

heart disease was 30% to 40% lower among nurses with the highest intake of

vitamin E from diet and supplements. Researchers found that the apparent benefit

was mainly associated with intake of vitamin E from dietary supplements. High

vitamin E intake from food was not

associated with significant cardiac risk reduction [15]. A 1994 review of 5,133

Finnish men and women aged 30-69 years also suggested that increased dietary

intake of vitamin E was associated with decreased mortality (death) from heart

disease [16].

Even though these observations are promising, randomized clinical trials raise

questions about the efficacy of vitamin E supplements in the prevention of heart

disease. The Heart Outcomes Prevention Evaluation (HOPE) Study followed almost

10,000 patients for 4.5 years who were at high risk for heart attack or stroke

[17]. In this intervention study the subjects who received 265 mg (400 IU) of

vitamin E daily did not experience significantly fewer cardiovascular events or

hospitalizations for heart failure or chest pain when compared to those who

received a placebo (sugar pill). The researchers suggested that it is unlikely

that the vitamin E supplement provided any protection against cardiovascular

disease in the HOPE study. This study is continuing, with the goal of

determining whether a longer duration of intervention with vitamin E supplements

will provide any protection against cardiovascular disease.

In a study sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of

the National Institutes of Health, postmenopausal women with heart disease who

took supplements providing 400 IU vitamin E and 500 mg vitamin C twice a day,

either alone or in combination with hormones, did not have fewer heart attacks

or deaths. There was also no change in progression of their coronary disease.

This study, The Women's Angiographic Vitamin and Estrogen (WAVE) trial, studied

423 postmenopausal women at seven clinical centers in the U.S. and Canada. In

postmenopausal women with coronary disease enrolled in this trial, neither

hormone replacement therapy nor antioxidant vitamin supplements provided

cardiovascular benefit [18].

Vitamin E and cancer

Antioxidants such as vitamin E are believed to help protect cell membranes

against the damaging effects of free radicals, which may contribute to the

development of chronic diseases such as cancer [4]. Vitamin E also may block the

formation of nitrosamines, which are carcinogens formed in the stomach from

nitrites consumed in the diet. It also may protect against the development of

cancers by enhancing immune function [19]. Unfortunately, human trials and

surveys that have tried to associate vitamin E intake with incidence of cancer

have been generally inconclusive.

Some evidence associates higher intake of vitamin E with a decreased incidence

of prostate cancer and breast cancer [20]. However, an examination of the effect

of dietary factors, including vitamin E, on incidence of postmenopausal breast

cancer in over 18,000 women from New York State did not associate a greater

vitamin E intake with a reduced risk of developing breast cancer [21].

A study of women in Iowa provides evidence that an increased dietary intake of

vitamin E may decrease the risk of colon cancer, especially in women under 65

years of age [22]. On the other hand, a study of 87,998 females from the Nurses'

Health Study and 47,344 males from the Health Professionals Follow-up Study

failed to support the theory that an increased dietary intake of vitamin E may

decrease the risk of colon cancer [23].

The American Cancer society recently released the results of a long-term study

that evaluated the effect of regular use of vitamin C and vitamin E supplements

on bladder cancer mortality in almost 1,000,000 adults in the U.S. The study,

conducted between the years 1982 to 1998, found that subjects who regularly

consumed a vitamin E supplement for longer than 10 years had a reduced risk of

death from bladder cancer. No benefit was seen from vitamin C supplements [24].

At this time researchers cannot confidently recommend vitamin E supplements for

the prevention of cancer because the evidence on this issue is inconsistent and

limited.

Vitamin E and cataracts

Cataracts are abnormal growths in the lens of the eye. These growths cloud

vision. They also increase the risk of disability and blindness in aging adults.

Antioxidants are being studied to determine whether they can help prevent or

delay cataract growth. Observational studies have found that lens clarity, which

is used to diagnose cataracts, was better in regular users of vitamin E

supplements and in persons with higher blood levels of vitamin E [25]. A study

of middle-aged male smokers, however, did not demonstrate any effect from

vitamin E supplements on the incidence of cataract formation [26]. The effects

of smoking, a major risk factor for developing cataracts, may have overridden

any potential benefit from the vitamin E, but the conflicting results also

indicate a need for further studies before researchers can confidently recommend

extra vitamin E for the prevention of cataracts.

What is the health risk of too much vitamin E?Most studies of the safety of

vitamin E supplementation have lasted for several months or less, so there is

little evidence for the long-term safety of vitamin E supplementation.

The Food and Nutrition Board of the Institute of Medicine has set an upper

tolerable intake level (UL) for vitamin E at 1,000 mg (1,500 IU) for any form of

supplementary alpha-tocopherol per day. Based for the most part on the result of

animal studies, the Board decided that because vitamin E can act as an

anticoagulant and may increase the risk of bleeding problems this UL is the

highest dose unlikely to result in bleeding problems.

Table 4 lists the Tolerable Upper Intake Levels (UL) of vitamin E in mg

alpha-tocopherol and IUs for children and adults (1 mg alpha-tocopherol vitamin

E = 1.49 IU). A UL for vitamin E for infants up to 12 months of age has not been

established.

Table 4: Tolerable Upper Intake Levels (UL) of vitamin E for Children and Adults

[5]

Age (years)

Males

(mg/day)

Females

(mg/day)

Pregnancy

(mg/day)

Lactation

(mg/day)

1-3

200

(=300 IU)

200

(=300 IU)

N/A

N/A

4-8

300

(=450 IU)

300

(=450 IU)

N/A

N/A

9-13

600

(=900 IU)

600

(=900 IU)

N/A

N/A

14-18

800

(=1,200 IU)

800

(=1,200 IU)

800

(=1,200 IU)

800

(=1,200 IU)

19-70

1,000

(=1,500 IU)

1,000

(=1,500 IU)

1,000

(=1,500 IU)

1,000

(=1,500 IU)

> 70

1,000

(=1,500 IU)

1,000

(=1,500 IU)

N/A

(=1,500 IU)

N/A

(=1,500 IU)

Vitamin E intakes and healthful dietsMany people are concerned about their fat

intake today. Your overall diet should be moderate in fat, but it is important

to include some healthful sources of fat, including those oils and nuts that

provide vitamin E. Including these foods in your diet will help you meet your

daily need for vitamin E. Meats, grain products, dairy products, and most fruits

and vegetables are generally not good sources of vitamin E. According to the

2005 Dietary Guidelines for Americans, " Nutrient needs should be met primarily

through consuming foods. Foods provide an array of nutrients and other compounds

that may have beneficial effects on health. In certain cases, fortified foods

and dietary supplements may be useful sources of one or more nutrients that

otherwise might be consumed in less than recommended amounts. However, dietary

supplements, while recommended in some cases, cannot replace a healthful diet. "

The Dietary Guidelines for Americans describes a healthy diet as one that:

emphasizes a variety of fruits, vegetables, whole grains, and fat-free or

low-fat milk and milk products;

includes lean meats, poultry, fish, beans, eggs, and nuts;

is low in saturated fats, trans fats, cholesterol, salt (sodium), and added

sugars; and

stays within your daily calorie needs.For more information about building a

healthful diet, refer to the Dietary Guidelines for Americans

http://www.healthierus.gov/dietaryguidelines and the US Department of

Agriculture's food guidance system (My Pyramid; http://www.mypyramid.gov).

About ODS

General Safety Advisory

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Posted Date:

10/7/2004

Updated:

1/23/2007 12:32 PM

References

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Sharon Lang

From: ilizzy03 <lizlaw@...>

Subject: [ ] Re: Speak supplement ?

Date: Sunday, October 5, 2008, 7:38 PM

Vitamin E reduces inflammation and is a powerful antioxidant. I do

wonder if the " negative " stories are simply of it working too well if

you know what I am saying. I also wonder about the fish oil rancidity

issues with the posts that claim a really fishy smell. I hope this all

gets studied because for the right kids at the right doseage I bet this

could be a big help.

In the interim, great food sources of vitamin k and E are listed at

whfoods.

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