Guest guest Posted July 22, 2008 Report Share Posted July 22, 2008 Not just companies -why is the AAP recommending statins to children?! I'm so tired of doctors experimenting on our growing children with drugs with known side effects that were only tested and meant for adults. Cholesterol is very important to a growing body and we won't know what this will mean for those that grow up on taking their statins with their Flintstone's multi for possibly decades. Besides outside of statins there is a clinically proven through Dr. from the Clinical Nutrition & Risk Factor Modification Center at St 's Hospital, Toronto natural way to help that works without side effect: http://nutrition.smatix.com/17478.php You want to check out the above link -I've shared this with many friends, family and doctors and it does work as well as the statin - without the side effects just like they found. Don't get me wrong -yesterday we went to Universal and for some reason there were more overweight kids than ever -two of which had trouble walking which is quite sad. But don't see how sticking a kid like that on a drug is going to be better than a change in lifestyle that the child can grow up with -and live a healthy life with Great video on this from Canada about the problem and the solution (no statins mentioned!) Instead of putting a band aid on a child to treat obesity -and a band aid that comes with it's own list of side effects at that -why not promote play, exercize, healthy foods and lifestyle? " Only 6 percent of American children aged 9 to 13 play outside, said Amy Pertschuk, managing director of the Children and Nature Network. " http://www.childrenandnature.org/index.php?/news/detail/agencies_and_organizatio\ ns_testify_before_congress_at_no_child_left_inside_/ The AAP is supposed to protect our kids and be a symbol of excellence in pediatric care. http://www.nytimes.com/2008/07/08/health/08well.html?ref=science http://www.medscape.com/viewarticle/577424 And some info about cholesterol Cholesterol homeostasis in the developing brain: a possible new target for ethanol M. Guizzetti Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, USA, marinag@... LG Costa Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, USA, Department of Human Anatomy, Pharmacology and Forensic Medicine, University of Parma, Italy Cholesterol is an essential component of cell membranes and plays an important role in signal transduction. This brief overview presents evidence from the literature that ethanol may affect cholesterol homeostasis and that, in the developing brain, this may be involved in its developmental neurotoxicity. The effects caused by inborn errors of cholesterol synthesis and by in utero ethanol exposure present several similarities in humans (eg, -Lemli-Opitz syndrome and fetal alcohol syndrome), as well as in animal models. Ethanol has a cholesterol-reducing effect on the cardiovascular system, and a protective effect against Alzheimer's disease, whose pathogenesis has been linked to altered cholesterol homeostasis in the brain. In vitro, ethanol affects several functions that are mediated by cholesterol and important for brain development, such as glial cell proliferation, synaptogenesis, neuronal survival and neurite outgrowth. The brain contains high levels of cholesterol, mostly synthesized in situ. Astrocytes produce large amounts of cholesterol that can be released by these cells and utilized by neurons to form synapses. Ethanol up-regulates the cholesterol transporter ATP binding cassette A1 and cholesterol efflux from primary astrocyte cultures without affecting cholesterol synthesis. Human & Experimental Toxicology (2007) 26, 355-360 Key Words: astrocytes • cholesterol • ethanol • fetal alcohol syndrome http://het.sagepub.com/cgi/content/abstract/26/4/355 While excess cholesterol may have deleterious consequences, as in the case of atherosclerosis, too little cholesterol may endanger the development of the brain. Different degrees of mental retardation are often observed in inborn errors of cholesterol synthesis, such as the –Lemli–Opitz syndrome or in maternal phenylketonuria, where the metabolite of accumulating phenylalanine, phenylacetate, is an inhibitor of cholesterol synthesis. Lack of cholesterol during brain development as a consequence of these genetic defects leads to severe brain damage, microencephaly and mental retardation, which are also hallmarks of the fetal alcohol syndrome (FAS). The brain relies on the in situ synthesis of cholesterol, which occurs mostly in astrocytes. http://linkinghub.elsevier.com/retrieve/pii/S0306987704004840 The next time you would like to thank somebody for a complete set of 20 digits after counting your newborn's fingers and toes, cholesterol might be all that you need to be grateful for! Cholesterol Plays An Important Role In Finger and Toe Development A new study conducted in mice has now found that cholesterol plays a very vital role in development of fingers and toes. The attachment of this pivotal chemical to a specific development protein is the key to proper digit development. Mice devoid of cholesterol developed digits in wrong places, in addition to extra digits. The results of this interesting study have been found in the online edition of the Proceedings of the National Academy of Sciences. http://www.bio-medicine.org/medicine-news/Cholesterol-Plays-An-Important-Role-In\ -Finger-and-Toe-Development-9617-1/ ===== Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 22, 2008 Report Share Posted July 22, 2008 Thank you for posting this ! Yes, high cholesterol is indeed NOT the villain it has been made out to be but very often (when not part of a true metabolic disorder which should definitely be identified and especially in children) it is a response to some inflammatory processes going on in the body, a self defense mechanism if you like, which just like with the body's natural defense the " FEVER " doctors too quickly jump to suppress without bothering to take into account its role in helping us ward of " attackers " . And the anti cholesterol drugs are with side effects that are unspeakable for something that may not even be a problem to begin with. And if reduction in cholesterol is indeed needed, natural remedies are much more effective. Very interesting reading. Thanks again! -Elena From: kiddietalk <kiddietalk@...> Subject: [ ] Re: Newbie here with 23 NOW bishenol A Date: Tuesday, July 22, 2008, 3:41 PM Not just companies -why is the AAP recommending statins to children?! I'm so tired of doctors experimenting on our growing children with drugs with known side effects that were only tested and meant for adults. Cholesterol is very important to a growing body and we won't know what this will mean for those that grow up on taking their statins with their Flintstone's multi for possibly decades. Besides outside of statins there is a clinically proven through Dr. from the Clinical Nutrition & Risk Factor Modification Center at St 's Hospital, Toronto natural way to help that works without side effect: http://nutrition.smatix.com/17478.php You want to check out the above link -I've shared this with many friends, family and doctors and it does work as well as the statin - without the side effects just like they found. Don't get me wrong -yesterday we went to Universal and for some reason there were more overweight kids than ever -two of which had trouble walking which is quite sad. But don't see how sticking a kid like that on a drug is going to be better than a change in lifestyle that the child can grow up with -and live a healthy life with Great video on this from Canada about the problem and the solution (no statins mentioned!) Instead of putting a band aid on a child to treat obesity -and a band aid that comes with it's own list of side effects at that -why not promote play, exercize, healthy foods and lifestyle? " Only 6 percent of American children aged 9 to 13 play outside, said Amy Pertschuk, managing director of the Children and Nature Network. " http://www.childrenandnature.org/index.php?/news/detail/agencies_and_organizatio\ ns_testify_before_congress_at_no_child_left_inside_/ The AAP is supposed to protect our kids and be a symbol of excellence in pediatric care. http://www.nytimes.com/2008/07/08/health/08well.html?ref=science http://www.medscape.com/viewarticle/577424 And some info about cholesterol Cholesterol homeostasis in the developing brain: a possible new target for ethanol M. Guizzetti Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, USA, marinag@... LG Costa Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, USA, Department of Human Anatomy, Pharmacology and Forensic Medicine, University of Parma, Italy Cholesterol is an essential component of cell membranes and plays an important role in signal transduction. This brief overview presents evidence from the literature that ethanol may affect cholesterol homeostasis and that, in the developing brain, this may be involved in its developmental neurotoxicity. The effects caused by inborn errors of cholesterol synthesis and by in utero ethanol exposure present several similarities in humans (eg, -Lemli-Opitz syndrome and fetal alcohol syndrome), as well as in animal models. Ethanol has a cholesterol-reducing effect on the cardiovascular system, and a protective effect against Alzheimer's disease, whose pathogenesis has been linked to altered cholesterol homeostasis in the brain. In vitro, ethanol affects several functions that are mediated by cholesterol and important for brain development, such as glial cell proliferation, synaptogenesis, neuronal survival and neurite outgrowth. The brain contains high levels of cholesterol, mostly synthesized in situ. Astrocytes produce large amounts of cholesterol that can be released by these cells and utilized by neurons to form synapses. Ethanol up-regulates the cholesterol transporter ATP binding cassette A1 and cholesterol efflux from primary astrocyte cultures without affecting cholesterol synthesis. Human & Experimental Toxicology (2007) 26, 355-360 Key Words: astrocytes • cholesterol • ethanol • fetal alcohol syndrome http://het.sagepub.com/cgi/content/abstract/26/4/355 While excess cholesterol may have deleterious consequences, as in the case of atherosclerosis, too little cholesterol may endanger the development of the brain. Different degrees of mental retardation are often observed in inborn errors of cholesterol synthesis, such as the –Lemli–Opitz syndrome or in maternal phenylketonuria, where the metabolite of accumulating phenylalanine, phenylacetate, is an inhibitor of cholesterol synthesis. Lack of cholesterol during brain development as a consequence of these genetic defects leads to severe brain damage, microencephaly and mental retardation, which are also hallmarks of the fetal alcohol syndrome (FAS). The brain relies on the in situ synthesis of cholesterol, which occurs mostly in astrocytes. http://linkinghub.elsevier.com/retrieve/pii/S0306987704004840 The next time you would like to thank somebody for a complete set of 20 digits after counting your newborn's fingers and toes, cholesterol might be all that you need to be grateful for! Cholesterol Plays An Important Role In Finger and Toe Development A new study conducted in mice has now found that cholesterol plays a very vital role in development of fingers and toes. The attachment of this pivotal chemical to a specific development protein is the key to proper digit development. Mice devoid of cholesterol developed digits in wrong places, in addition to extra digits. The results of this interesting study have been found in the online edition of the Proceedings of the National Academy of Sciences. http://www.bio-medicine.org/medicine-news/Cholesterol-Plays-An-Important-Role-In\ -Finger-and-Toe-Development-9617-1/ ===== Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.