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ACTOS Prescription

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> > Hello all! I took my 2 year old son to a DAN! doctor and he

> > prescribed ACTOS for him. Actos is normally for diabetics. He

said

> > he's seen remarkable changes where the children start speaking

> within

> > a week, as well as an improvement in behavior and eye contact.

> >

> > I will quote exactly what the doctor said to me about this -

> > " The current reasoning behind me wanting to use Actos is because

it

> > fixes the immune system and has been found to lower

> > neuroinflammation. There are more and more findings that

children

> > with ASD have neuroinflammation and that is a major contributing

> > factor to their symptoms. It's not like you can give the kids an

> anti-

> > inflammatory like Motrin and the get better. In this case, it is

a

> > very complicated pathway involving something known as Peroxisome

> > proliferator-activated receptors (PPARs). They are members of

the

> > nuclear hormone receptor superfamily of ligand-activated

> > transcription factors that are related to retinoid, steroid and

> > thyroid hormone receptors. PPARs play an important role in many

> > cellular functions including lipid metabolism, cell

proliferation,

> > differentiation, adipogenesis and inflammatory signaling. PPARs

> have

> > been found to interact with a number of endogenous lipids and

drugs

> > for the treatment of human metabolic diseases. "

> >

> > I was wondering if anyone knew anything about this. I'm somewhat

> > apprehensive about giving this to such a young child, especially

> when

> > this doctor has only been using " experimenting " with it for 3

> months

> > now. He said he hasn't had any complications as far as the liver

> > goes, but I'm still nervous.

> >

> > Any information would be helpful! Feel free to email me

directly.

> >

> > Thank you!

> > Patti

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