Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 > Lynn, $202.50 for 50 pills?!! It would be cheaper going to different docs until you find one that agrees. I paid $11.50 plus $4.95 shipping for 30. Also, how do you know if their even compounded correctly? Margie > From: " Lynn Arnett " <lynarn@...> > > Subject: [low dose naltrexone] Naltrexone > > > > $202.50 for 50 tablets,this includes shipping and a drug fee. > All we can do is stop a ton of stress and try and get better. > Good luck to all. > Lynn > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 I have received a few e-mails stating they can't get through with the address I havegiven for the Revia,50.m.g. Try this and see if this one will go through for you. www.importeddrugs.com Good Luck! ----- Original Message ----- From: Lynn Arnett low dose naltrexone Sent: Thursday, September 04, 2003 10:30 PM Subject: [low dose naltrexone] Naltrexone To all of you that are having a hard time convincing your Doctor's that our time has been cut short and we have the right to choose the drug of our choice,you may want to consider following GOODSHAPES recipe and ordering it yourself.If you have been brave enough to inject yourself with one of the 4 interferons with the side effects they create,then you should be brave enough to want to make yourself better and take it upon yourself to do just that without your doctor's adverse advise. I have searched the world over to locate the Naltrexone,aka Revia and will share with you the site you are able to order it from to your door. http.//www.freefiliate.com/cgi-bin/orderit/viewcart.cgi?importeddrugs Your supplies will be to you in 2 business days. $202.50 for 50 tablets,this includes shipping and a drug fee. All we can do is stop a ton of stress and try and get better. Good luck to all. Lynn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 awesome info. Thx, Lynn. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 After looking the imported drugs site, it appears to me that they require a prescription. Right back where we started. Trying to convince some closed-minded Doctor to give a prescription. Noland ----- Original Message ----- From: Lynn Arnett low dose naltrexone Sent: Friday, September 05, 2003 9:09 AM Subject: Fw: [low dose naltrexone] Naltrexone I have received a few e-mails stating they can't get through with the address I havegiven for the Revia,50.m.g. Try this and see if this one will go through for you. www.importeddrugs.com Good Luck! ----- Original Message ----- From: Lynn Arnett low dose naltrexone Sent: Thursday, September 04, 2003 10:30 PM Subject: [low dose naltrexone] Naltrexone To all of you that are having a hard time convincing your Doctor's that our time has been cut short and we have the right to choose the drug of our choice,you may want to consider following GOODSHAPES recipe and ordering it yourself.If you have been brave enough to inject yourself with one of the 4 interferons with the side effects they create,then you should be brave enough to want to make yourself better and take it upon yourself to do just that without your doctor's adverse advise. I have searched the world over to locate the Naltrexone,aka Revia and will share with you the site you are able to order it from to your door. http.//www.freefiliate.com/cgi-bin/orderit/viewcart.cgi?importeddrugs Your supplies will be to you in 2 business days. $202.50 for 50 tablets,this includes shipping and a drug fee. All we can do is stop a ton of stress and try and get better. Good luck to all. Lynn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 Hi Margie, I have no med. ins, so going to different docs until I find one that will prescribe the LDN could end up costing me more.(how much is a phone consult with Dr. B?) As far as compounding, these 50 mg tabs (while not pure naltrexone powder) are the ones used to also make up the 3-4.5 tabs. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 And by the way, 30 tabs lasts me almost a year, 50 would last well over a year and a half. You're cost is about $198 per year. About the same price. :0) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 5, 2003 Report Share Posted September 5, 2003 oops, I take that back. I just ordered 30, to last about a year. Cost me about $120. It IS cheaper to make your own. :0) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 6, 2003 Report Share Posted September 6, 2003 Thank you so much Lori...I'm not giving up. And good thoughts for you too. We are doing our best...thats all we can do. Hugs, Sally > I'm so sorry you're not doing good. I'm not sure this will help or > discourage you. I haven't had much luck so far either. I talked to Dr Sullivan and he > suggest taking it every other night. I'm on 4.5 . I think like you. I'll stop > and start all over going with Dr B. The Druggist I went with may not have > used the right filler. He's a local Pharmacy here Indianapolis. Been trying ldn > almost 3 months. Not to be discouraged we just have to find right dosage for > us. HANG IN THERE. GOOD LUCK TO YOU. > > Lori Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2003 Report Share Posted October 23, 2003 This email would convince many doctors to give it a expirmental tril ----- Original Message ----- From: Cabbie54@... low dose naltrexone ; spotlight_ldn ; red857@... Sent: Wednesday, October 22, 2003 6:50 PM Subject: [low dose naltrexone] Naltrexone Contents: Overview Pharmacology Patient experience References OverviewNaltrexone is a commercially avaliable prescription drug, approved by the FDA since the early 1980s, which is manufactured by DuPont and made available under the trade name of ReVia. It has been used for a number of years as an adjunct to the treatment of opioid addictions, and sometimes alcoholism as well. There has been off-label experimenation with this drug for other purposes, namely in the treatment of autism, obesity, and certain types of cancer. Naltrexone blocks opioid receptors on the surface of cells. As a result, opiates will not produce euphoria and their effect on pain may be less predictable. It is thought that when very small doses are used, naltrexone will increase natural endorphins in the body which play a role not only in mood regulation but also in the level of immune functioning. Two physicians have experimented with the use of naltrexone in cancer: Dr Bihari in NYC, and Dr Margaret Lewin, an oncologist at New York Hospital-Cornell Medical Center. Dr Bihari looked for an opiod antagonist when he realized this could boost the immune functioning of his AIDS patients. When he got good results with it, he then postulated that certain cancers that have plenty of opioid receptors in their cells, could also be influenced by this drug. He suggested it in 1993 to Dr Lewin who has tried it in a few patients with lymphoma. Early research showed that heroin inhibits the growth of certain tumors, and that a certain endorphin called metenkephalin prolongs the survival of mice with leukemia, melanoma, and other cancers. Further research found that opiate receptors play a key role in the action of these endorphins. Naltrexone was used in these studies. Other studies showed that high doses of naltrexone stimulated tumor growth, and very small doses prolong survival in mice with cancer, and protect those mice at risk of developing cancer. It was noted that opiate peptides play a key role in regulating the growth of certain cancers, and then hypothesized that small daily doses of naltrexone would enhance the protective effect of endorphins by increasing the number and density of opiate receptors on tumor cells. The effects of the endorphins are thought to work against the cancer cells indirectly by inhibiting their DNA synthesis and mitosis, and other subtle changes. There is a significant body of literature that suggested to Dr Bihari that endorphins are very involved in the regulation of immune function, and led to his initial experimentation with HIV positive patients. He and his colleagues found that low dose naltrexone increases beta-endorphins in healthy volunteers within 2 hours, with a greater rise some 12-16 hours later if the dose was given in the late evening. Their 12 week placebo controlled trial in AIDS patients showed decline in the levels of alpha interferon and better protection against opportunistic infections (no patients of 22 in the active arm developed infections, while 5 of the 16 placebo arm patients did). Another placebo controlled trial showed a significant increase in NK (natural killer) cells, as well as lymphomcytes and CD4s. Dr Bihari thinks that naltrexone may work in the following ways: by increasing the endorphin levels, by increasing opiate receptors in tumor cell membranes and thus making the cells more susceptible to endorphin effects, and by increasing the levels of NK cells and their activity. The cancers thought most responsive to low dose naltrexone originate in tissues with high densities of opioid receptors, particularly lymphomas (including Hodgkin's disease, NHL, CLL, and multiple myeloma) and cancer of the pancreas. Other cancers also quite high in these receptors are colorectal cancers, metastatic melanoma, neuroblastoma, glioma, cancer of the small intestine, prostate cancer, and some endocrine cancers. Dr Bihari began to use naltrexone in cancer in 1985 in a patient with NH lymphoma that recurred and the patient refused further chemo. Her large groin tumors regressed within 12 weeks and she died 4 years later of an unrelated cause while still in remission. Dr Bihari introduced Dr Lewin to naltrexone in 1993, and she has apparently been using it in her practice with some cancer patients who have exhausted mainstream treatments. An indetermined percentage ("sizable minority") of these patients have had success with it, and Dr Lewin has been reported to say she considers the results "suggestive." She has not used it with untreated patients. Naltrexone for cancer is used at 3 mg per day, once a day, at bedtime. Since the drug only comes in 50 mg pills, a compounding pharmacy has to grind the pill down and make low dose pills. Dr Bihari feels that these pills are more stable than liquid made from the 50 mg pill. There are a number of pharmacies around the country that make it available. Check with your local compounding pharmacy, or try Apothecure at 1-800-969-6601, or Pharmacy at 603-539-2020. Back to top PharmacologyPharmaceutical information on naltrexone hydrochloride can be found in the Physicians' Desk Reference (also available in public libraries). It is classified as a pure opioid antagonist. It will block physical dependence on opiate drugs like heroin, morphine et al. It will cause withdrawal symptoms in people habituated to these substances. It is mostly eliminated by the kidneys. Some of it is recycled by the liver. It is rapidly absorbed after ingestion, mostly from the GI tract. Peak plasma levels occur about 1 hour after dosing, and the effect lasts 24-72 hours. While seemingly safe at low levels, it has been shown to be a hepatotoxin (liver poison) at dosages of about 300 mg per day in healthy volunteers. Its effects in pregnancy and lactation has not been studied. Studies in patients who have severely compromised liver and kidney function have not been conducted. Its safety in children has not been established. It is used at 5o mg per day for its approved use in opioid addiction. Side effects reported at these levels: GI upset in about 15 % of patients, Contraindicated in patients who are using opioid pain killers, patients with a history of sensitivity to naltrexone, patients with acute hepatitis or liver failure. It has the capacity to cause hepatocellular injury if given in excessive doses (about 5 times or less). It does not appear to be a hepatotoxin at 50 mg per day. If a patient must receive opioid analgesics while using naltrexone, the amount required may need to be adjusted upward, and careful monitoring is required. Patients are advised to look for signs of liver toxicity when using this product: white stools, dark urine, yellowing of eyes, or ongoing abdominal pain. Patients taking naltrexone may not benefit from opiate-containing medicines such as cough syrups, cold and antidiarrheal preparations, and opioid analgesics. In carcinogenesis studies on rodents, there was a small increase in mesotheliomas and vascular tumors. Other rare side effects include: tearfulness, dizziness, mild nausea, abdominal cramps, restlessness, body or muscle pains, and sinus problems. Volunteers who took 800 mg over a week showed no signs of overdose. Deaths in animals do not occur until the animal receives more than 1000 mg per kg of weight. When considering the information on the side effects and its use in cancer, please remember that in cancer, the dosage is only 3 mg per day; this is only 6% of the customary prescription dose. Back to top Patient experiencesSeveral lymphoma patients on the nhl-other list have begun to experiment with this substance, but it is too early to report any results. Please write of your experiences with lymphoma or other cancers and they will be added to the record here. Back to top ReferencesZagon, IS et al. Naltrexone prolongs the survival time of mice treated with neuroblastoma. Life Sci 28, pp 1095-1102, 1981. , PM et al. Enhancement of natural cytotoxicity by beta-endorphin. J immunol 130, 1983, pp 1658-1662. Plotnikoff, NP et al. Enkephalins and immunomodulators. Immunopharmacol 5, pp 437-441, 1983. Zagon, IS et al. Endogenous opioids and the growth regulation of a neural tumor. Life Sci 43, pp 1313-1318, 1988. White, L. Only one pill a day keeps some cancers at bay. New Horizons (newsletter of the Brewer Science Library), Spring 1999, pp 1, 2, 4, 5, 10. This is the article that has caused a stir in the cancer patient community. I am trying to get premission to post it on the site. In synopsis: Ms. White, possibly with the Brewer Library, has written a popularizing article with references upon request. She states that Dr Bihari found that the blood of AIDS and cancer patients runs very low in endorphins, and looked for some means to increase it. Naltrexone showed to increase two of them. He began to use it with his AIDS patients with what he felt were very good results (some patients have had no disease progression as long as 8 years), and reports that Dr Lewin shows a mean of 4.5 years of sustained remission for her lymphoma, CLL and HD patients [plus one recurrence when the patient stopped the drug]. White says that clinical studies of large groups of patients are in the planning stage. She posts a table that seems to claim (the article is not quite clear) that of the 25 patients treated -- but does not say by whom -- (colon, pancreas, melanoma, HD, NHL, CLL, MM, prostate, neuroblastoma), 21 went into remission, two experienced partial shrinkage and added standard therapy, one did not respond, and one is too recent to evaluate. Duration of remissions is mostly not reported. She recounts the cases of two patients with NHL who came to Dr Bihari after poor response to their second chemo after a relapse, who then seemed to improve dramatically on naltrexone. White cites from Bihari's letter in which he states that the treatment has particular promise in pancreatic cancers, and that 4 cases of 5 he knows about have gone into long term remission. He also treated a patient with melanoma mets to the brain who has been in remission for 12 years. LINKS New Horizon article, corrected by Dr Bihari at www.datafork.com/naltrexo.htm Various abstracts on NTX at www.datafork.com/ntxabstracts.htm Back to top Back to alternatives menu Back to main menu Researched and written by Vera Bradova © 1999 Updated 4-30-1999 This page hosted by Get your own Free Home Page Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 17, 2004 Report Share Posted January 17, 2004 Do you mean 2.5mg????? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2005 Report Share Posted January 22, 2005 Naltrexone Hi All Can anyone tell me the price of 30 x 50mgs Naltrexone tablets in US$ or even better 100 x 50mgs tablets. you can reply on the net or to mlfraser@... Many thanks in advance Malcolm No virus found in this outgoing message.Checked by AVG Anti-Virus.Version: 7.0.300 / Virus Database: 265.6.13 - Release Date: 2005/01/16 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2005 Report Share Posted January 22, 2005 On the LDN website the quote for 30 of the low dose was US$38. locally obtained for $36 - unable to obtain a quote for 50mg due to Sat PM time. Phone call to second compunding pharmacy revealed $130 for 30 fo 50mg and $457 for 100. The pharmacy I use quoted $117.04 and $401.55 for the 30/100 of the 50mg. Naltrexone Hi All Can anyone tell me the price of 30 x 50mgs Naltrexone tablets in US$ or even better 100 x 50mgs tablets. you can reply on the net or to mlfraser@... Many thanks in advance Malcolm No virus found in this outgoing message.Checked by AVG Anti-Virus.Version: 7.0.300 / Virus Database: 265.6.13 - Release Date: 2005/01/16 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 23, 2005 Report Share Posted January 23, 2005 Naltrexone Hi All Can anyone tell me the price of 30 x 50mgs Naltrexone tablets in US$ or even better 100 x 50mgs tablets. you can reply on the net or to mlfraser@... Many thanks in advance Malcolm No virus found in this outgoing message.Checked by AVG Anti-Virus.Version: 7.0.300 / Virus Database: 265.6.13 - Release Date: 2005/01/16 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 21, 2006 Report Share Posted May 21, 2006 Hi all, I just heard about a drug called Naltrexone. It is being used in small doses (called LDN---low dose naltrexone) to treat celiac disease and autism. Also being used for AIDS patients and other auto-immune diseases. Has anyone heard of this? Anyone using it? thanx, Lori Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 23, 2006 Report Share Posted May 23, 2006 I am familiar with low dose naltrexone (LDN) and it's treatment with autoimmume diseases and AIDS and MS and parkinsons etc (I was a research pharmacologist). Naltrexone is quite an old drug which was used in higher doses for withdrawal symptoms for opioids and alcoholism. It has recently been used at much smaller doses and the results are encouraging. There have been no studies done on the use of LDN with celiac patients but there is some anecdotal evidence that it helps - through it autoimmune actions. I am trying to find out more as although I was familar with LDN, I hadn't heard of it's use with celiac disease. Only a few physicians are using it and studying it. There is currently a study of it's use with Crohn's disease. If you want more info, look at www.low dose naltrexone.org This is mainly one physician's results but it's interesting to see what he is finding. I'll post any further information I find. Ruth Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 23, 2006 Report Share Posted May 23, 2006 --- ruthebaillie <ruthebaillie@...> wrote: > If you want more info, look > at www.low dose naltrexone.org This is > mainly one physician's results but it's interesting > to see what he is finding. > > I'll post any further information I find. > Ruth thanx, Ruth---that would be interesting. My brother's shrink (of all people) told him about it. I actually have seen that web site. I wonder what the effect would be on CD? Wouldn't you still need to be on the diet? If so, what's the point? " I wrestled with reality for 36 years, and I'm happy to say that I finally won out over it. " ---Elwood P. Dowd Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 23, 2006 Report Share Posted May 23, 2006 I did contact someone about LDN, asking how specifically it helped celiac patients. The people I contacted only had second-hand data/anecdotal responses The response I got from them was: " Suggest you approach the decision of whether to use LDN this way: if you are over 40 years old, you know that you no longer have the strong immune system you should have had in your youth. At worst, nightly LDN will afford a degree of protection against future infections and tumor formation -- whatever relief from celiac disease that you receive will be a bonus. " It is a very safe drug with very low incidence of side effects - but I'd want to see more evidence before I take it. I will talk to my physician about it next time I see her. Let me know if you find out more. Ruth (New quotation I just found) - " Life consists not in holding good cards but in playing those you hold well " Josh Billings. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 23, 2006 Report Share Posted May 23, 2006 for the other anecdote, Epipen use as an allergy life saver is a " side effect " of its primary use... so a drug for autoimmune disease could have a " side effect " use for one specific autoimmune like CD.. who knows... As for staying on the diet: the same way allergy medications are helpful when total avoidance is not possible, if there is a " softener " for gluten that MUST be in a Celiac diet (I'm thinking medications that do not exist in a GF form.. that is many many specific and not replacable medications) Anyway, if it could help, it could be a supplemental pill to a gluten loaded medication for a celiac.???? And no, I dont believe there will ever be a " magic pill " that would let a CD eat tons of pasta everyday.. I'm not sure that was the point first hand. (you dont like rice pasta? ;-) ) Sophie > > I am familiar with low dose naltrexone (LDN) and it's treatment with autoimmume diseases > and AIDS and MS and parkinsons etc (I was a research pharmacologist). Naltrexone is > quite an old drug which was used in higher doses for withdrawal symptoms for opioids > and alcoholism. It has recently been used at much smaller doses and the results are > encouraging. > > There have been no studies done on the use of LDN with celiac patients but there is some > anecdotal evidence that it helps - through it autoimmune actions. I am trying to find out > more as although I was familar with LDN, I hadn't heard of it's use with celiac disease. > > Only a few physicians are using it and studying it. There is currently a study of it's use > with Crohn's disease. If you want more info, look at www.low dose naltrexone.org This is > mainly one physician's results but it's interesting to see what he is finding. > > I'll post any further information I find. > Ruth > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 I have also researched Naltrexone, but cannot find a doctor that will prescribe it. It has been used with much success for adults with "addiction" or obsessive difficulties, especially with eating disorders. The use in children has not been studied or reported though-if you find more information I would certainly love to hear about it. My daughter has incredibly severe addictive type food issues and it leads to both aggression toward others and toward herself. We are desperate for help. She is 13 years old. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 Dr Demio www.drdemio.com prescribes it and has studied the drug. Our ped neuro dr reed at kidslinkohio.com also does! It has been the most successful drug we have used with my son not only for it's calming but also for it's immune modulatingproperties... Call with questions 2165341231 On Jan 24, 2010, at 8:56 AM, elaynasmom@... wrote: I have also researched Naltrexone, but cannot find a doctor that will prescribe it. It has been used with much success for adults with "addiction" or obsessive difficulties, especially with eating disorders. The use in children has not been studied or reported though-if you find more information I would certainly love to hear about it. My daughter has incredibly severe addictive type food issues and it leads to both aggression toward others and toward herself. We are desperate for help. She is 13 years old. Quote Link to comment Share on other sites More sharing options...
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