Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 Hi everyone does anyone if LDN has helped stabilize-prevent (or aggravate) autoimmune diabetes either Latent Autoimmune Diabetes of Adults (typically slow onset-so probably easier to intervene) & /or antibody-positive type 1 regardless of age? It appears about 10% of Westernized countries adult population presenting with pre-diabetes (particularly lean-non-obese adults between ages 30-50) may have pancreatic autoantibodies that increases their risk of insulin-dependency compared to those without such antibodies making it far more prevalent than classic onset type 1: http://www.actionlada.org/why/why.html From: http://www.low dose naltrexone.org/ldn_and_ai.htm " There exists a common notion that the immune system in a person with an autoimmune disorder is too strong and, in its exuberance, targets a body tissue for attack. Rather, the evidence is more consistent with autoimmunity resulting from immunodeficiency.1 Kukreja et al have demonstrated that multiple immunoregulatory T cell defects lie behind Type 1 diabetes both in humans and in non-obese diabetic mice.2 Sacerdote et al measured low beta-endorphin levels in two animal examples of autoimmune disease — a mouse strain with a lupus-like syndrome and a strain of chicken with an autoimmune thyroiditis.3 They had significantly lower hypothalamic concentrations of the opioid than normal controls. In each case, the low levels of beta- endorphin were found well before the expression of autoimmune disease. This adds to considerable evidence of a key role for endorphins in regulating immune responses and suggests a therapeutic pathway. Bihari et al found that a low oral dose of the opioid antagonist naltrexone, when taken at bedtime, led to a doubling or tripling of low levels of circulating beta-endorphin.4 Bihari has since treated some 100 people with autoimmune disorders. None of them has progressed further while the patient continued taking low dose naltrexone each night at bedtime. Since no side effects are apparently associated with its use, this medication might well be studied as a possible preventive for Type I diabetes in those youngsters with beta-cell autoantibodies. " Appreciate any replies, Josh Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 21, 2007 Report Share Posted March 21, 2007 Actually that was just a quote from the website. My original posts stands largely as an inquiry... Josh > > joshdeanrichards - this is the exact way i came to understand why and how > LDN works on autoimmune diseases!!!! thanx for the simple explanation that > confirmed my thought processes!! > > marshiris Quote Link to comment Share on other sites More sharing options...
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