Guest guest Posted March 18, 2007 Report Share Posted March 18, 2007 HI Anne, I'm not trying to be "picky" = I think that's a typo - "Amino Proteins"...they are amino acids which are the building blocks of protein?? I dunno really, I'm trying to learn about "short medium and long chain" amino acids, which as I understand relates to the degree they've been bonded to lipids, and it affects metabolic availability - how they then go on to bond to more complex proteins in the body/cells, etc... If so it's interesting that Copaxone is then essentially an amino acid "balancing" therapy. I like it, whatever the controversy. I probably have that "a little knowledge is a dangerous thing" thing... S ANNE <anne_white53@...> wrote: The page here says: *Copaxone is four Amino Acids consisting of: L-Glutamic Acid; L-Alalinine; L-Tyrosine and L-Lysine. Tyrosine: Promotes overall health L-Lysine: reduces Herpes-Simplex Viral.Lesions. Ya' know my onw personal theory on MS is: "possibly caused by The Herpes Virus from Mono. I cannot comment on on the L-Glutamic or the L-Alanine. I know both are Amino Proteins. Proteins are extremely necessary for cell-repair and cell-maintennace. Combine the Copaxone with the LDN and Vtiamins such as A and B-Compelx w/ Vit.C. IMO. Choose a color Black Blue Brown Clear Gold Gray Green Lavender Multi-colored Off-white Orange Peach Pink Purple Red Tan Turquoise White Yellow Choose a shape 3 sided 5 sided 6 sided 7 sided 8 sided Diamond Oblong Other Rectangle Round Square Close Find a Drug Advanced Search Advanced Consumer Consumer Copaxone font size A A A Copaxone® (Teva Neuroscience)(glatiramer acetate injection) DESCRIPTION Copaxone® (Teva Neuroscience)(glatiramer acetate injection) COPAXONE® is the brand name for glatiramer acetate (formerly known as copolymer-1). Glatiramer acetate, the active ingredient of COPAXONE®, consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid,L-alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons. Chemically, glatiramer acetate is designated L-glutamic acid polymer with L-alanine, L-lysine and L-tyrosine, acetate(salt). Its structural formula is: (Glu, Ala, Lys, Tyr) x.X CH3COOH (C5H9NO4. C3H7NO2. C6H14N2O2. C9H11NO3) x.x C2H4O2 CAS- 147245-92-9 COPAXONE® Injection is a clear, colorless to slightly yellow, sterile, non-pyrogenic solution for subcutaneous injection. Each 1.0 mL of solution contains 20 mg of glatiramer acetate and 40 mg of mannitol, USP. The pH range of the solution is approximately 5.5 to 7.0. The biological activity of COPAXONE® is determined by its ability to block the induction of EAE in mice. Check prices for this drug Get Started News From WebMD New FDA Warnings for Anemia Drugs Tekturna Is First in a New Class of Blood Pressure Drugs FDA Warns About Asthma Drug, Xolair FDA Highlights ADHD Drug Warnings Watch Now. Get Answers. WebMD Daily Get breaking medical news. Copaxone Description Clinical Pharmacology Indications & Dosage Side Effects & Drug Interactions Warnings & Precautions Overdosage Contraindictions Patient Information Reference Center Health Resources Prescription Medicine FDA Overview Home Pharmacy Common Health Tests Family Medical Records Doctors: Specialties and Training Search MedTerms Dictionary for Health Definitions & Medical Abbreviations Yes! You may freely link to RxListFind out how to add an RxList Search box to your website. Get RxList-trusted information when you Google! Acid Reflux Disease Allergic Asthma Info Alzheimer’s Questions? Bipolar Rx Info Bone Health Tips Cancer Treatments Cardiac Device Videos Dental Health Guide Heart Failure Solutions Hepatitis Treatment Living with Lymphoma Skin Care Quiz Take Asthma Help Test Targeting Breast Cancer Vision Problems? RxList Home| Contact RxList|About RxList|Terms & Conditions|Privacy Policy|Sponsor Policy|More Search Options|Drug Brand Name A-Z WebMD®|MedScape®|eMedicineHealth®|MedicineNet® Copyright © 2007 by RxList Inc.RxList does not provide medical advice, diagnosis or treatment. See additional information. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 19, 2007 Report Share Posted March 19, 2007 Go back to school and reread the books on amino acids. Wikipedia has a decent review of amino acids: http://en.wikipedia.org/wiki/Amino_acid The four Copaxone amino acids hooked together (a polypeptide) is supposed to look a bit like myelin. Our immune system attacks the Copaxone and not our myelin. My experience with these things is the characteristics of the side chain such as if it's alaphatic, aromatic, etc. plays a little larger role than the physical size. To keep flames from being shot at me; the size does matter some when the amino acids are trying to line up and connect with other amino acids. > > HI Anne, I'm not trying to be " picky " = I think that's a typo - " Amino Proteins " ...they are amino acids which are the building blocks of protein?? I dunno really, I'm trying to learn about " short medium and long chain " amino acids, which as I understand relates to the degree they've been bonded to lipids, and it affects metabolic availability - how they then go on to bond to more complex proteins in the body/cells, etc... > If so it's interesting that Copaxone is then essentially an amino acid " balancing " therapy. I like it, whatever the controversy. > I probably have that " a little knowledge is a dangerous thing " thing........ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 19, 2007 Report Share Posted March 19, 2007 Thanks alright....I'm going to have to really understand the interplay here, at least to grade school level...() (haven't actually read ANY books, YET, on aminos), if I'm going to help Didi make decisions on her therapeutic mix. I'll definitely check out the wiki article, I'd scanned it but not in depth. If I get the general drift, though, size may be a central issue regards effective nutritional strategies (i mean in our case, where we're for now bypassing the gut), whereas if we're trying to target actual tasks, stimulating certain functions etc, then the aromatic/alaphatic thingie begins to come into play? And the Copaxone mix is effectively a small protein. It's al little oblique to our needs to know this - we're dealing with recnac, not MS - but I guess I'm naturally curious (though counting my 9 lives ) S.alrightguy123 <alrightguy123@...> wrote: Go back to school and reread the books on amino acids. Wikipedia has a decent review of amino acids:http://en.wikipedia.org/wiki/Amino_acidThe four Copaxone amino acids hooked together (a polypeptide) issupposed to look a bit like myelin. Our immune system attacks theCopaxone and not our myelin.My experience with these things is the characteristics of the sidechain such as if it's alaphatic, aromatic, etc. plays a little largerrole than the physical size. To keep flames from being shot at me;the size does matter some when the amino acids are trying to line upand connect with other amino acids.>> HI Anne, I'm not trying to be "picky" = I think that's a typo -"Amino Proteins"...they are amino acids which are the building blocksof protein?? I dunno really, I'm trying to learn about "short mediumand long chain" amino acids, which as I understand relates to thedegree they've been bonded to lipids, and it affects metabolicavailability - how they then go on to bond to more complex proteins inthe body/cells, etc...> If so it's interesting that Copaxone is then essentially an aminoacid "balancing" therapy. I like it, whatever the controversy.> I probably have that "a little knowledge is a dangerous thing"thing........> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 19, 2007 Report Share Posted March 19, 2007 The Copaxone amino acids are NOT nutritional. It's a protein by definition because there are multiple amino acids connected together. > > If I get the general drift, though, size may be a central issue regards effective nutritional strategies (i mean in our case, where we're for now bypassing the gut), whereas if we're trying to target actual tasks, stimulating certain functions etc, then the aromatic/alaphatic thingie begins to come into play? And the Copaxone mix is effectively a small protein. It's al little oblique to our needs to know this - we're dealing with recnac, not MS - but I guess I'm naturally curious (though counting my 9 lives ) > > S. > > Go back to school and reread the books on amino acids. > > Wikipedia has a decent review of amino acids: > http://en.wikipedia.org/wiki/Amino_acid > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 I think we're on the same page (though I may be only looking at the illustrations LOL). The total parenteral nutrition mix that my Diane receives ARE nutritional (hopefully), but the Copaxone protein is 'targeted' at a specific task, as I said, not simply building up metabolic resources. And my issue is, of course, whether better nutritional effect is achieved with shorter, or longer amino acid chains. This all is of interest to me because someone (not here) put in my ear that the shorter chains aren't as useful, sort of tend to just float around in serum and then get wasted. I might have that inverted - simply dunno the science - but the wonderful Dr. Fairful- who is running the TPN Program here has said he'd be open to discussion, amendments. Since we're making such effort daily with this regime, we want to optimize the effort, allrightguy.alrightguy123 <alrightguy123@...> wrote: The Copaxone amino acids are NOT nutritional. It's a protein bydefinition because there are multiple amino acids connected together.>> If I get the general drift, though, size may be a central issueregards effective nutritional strategies (i mean in our case, wherewe're for now bypassing the gut), whereas if we're trying to targetactual tasks, stimulating certain functions etc, then thearomatic/alaphatic thingie begins to come into play? And the Copaxonemix is effectively a small protein. It's al little oblique to ourneeds to know this - we're dealing with recnac, not MS - but I guessI'm naturally curious (though counting my 9 lives )> > S.> > Go back to school and reread the books on amino acids. > > Wikipedia has a decent review of amino acids:> http://en.wikipedia.org/wiki/Amino_acid> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 personal opinion: I don't think the length of the chains have much to do with how well the amino acids are used. Our bodies make quite a few amino acids on their own. There are something like 7 or 10 amino acids our bodies don't make but need. Maybe a better question is what is her body making or not making and which amino acids does she need. I don't know if there is a blood test, stool test, urine test that would answer these questions. > > I think we're on the same page (though I may be only looking at the illustrations LOL). > The total parenteral nutrition mix that my Diane receives ARE nutritional (hopefully), but > the Copaxone protein is 'targeted' at a specific task, as I said, not simply building up metabolic resources. And my issue is, of course, whether better nutritional effect is achieved with shorter, or longer amino acid chains. > This all is of interest to me because someone (not here) put in my ear that the shorter chains aren't as useful, sort of tend to just float around in serum and then get wasted. I might have that inverted - simply dunno the science - but the wonderful Dr. Fairful- who is running the TPN Program here has said he'd be open to discussion, amendments. > Since we're making such effort daily with this regime, we want to optimize the effort, alrightguy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 Yes, there are test for amino acids and really she should be tested and aminos and other nutrients added to her formula based on those tests. Find a DAN! doc or orthomolecular doc to do the testing. Metametrix is the name of one lab that does those tests. How much LDN is she on for what period of time. mjh Posted by: "alrightguy123" alrightguy123@... alrightguy123 Mon Mar 19, 2007 8:46 pm (PST) personal opinion: I don't think the length of the chains have muchto do with how well the amino acids are used. Our bodies make quite afew amino acids on their own. There are something like 7 or 10 aminoacids our bodies don't make but need. Maybe a better question is whatis her body making or not making and which amino acids does she need.I don't know if there is a blood test, stool test, urine test thatwould answer these questions. AOL now offers free email to everyone. Find out more about what's free from AOL at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 'Therein lies the rub', alrightguy. We came within a hair'sbreadth of spending upwards of $1500, and then $5000 for proprietory supplements, with a company here in Ottawa that says they do deep level HPLC analysis of amino's from blood - and therefore can identify deficiencies that they then address with their proprietory supplements. They present that there are the 'essential' amino acids, the 'non-essential' amino acids, (those made 'easily' by the body) and a class they call 'provisionally essential', (this latter with which I'm not in great disagreement with, having heard this said in various places. ) I was hearing all the right things from them in terms of their stance regards the Big Cancer Establishment (pretty hard to deny in general, but most folk are not monsters, IMHO - and chemo, rad, and especially surgery has it's place, often critical), but decided upon hearing statements from the owner that Diane would feel radically better, in days, (he said this 2X when pressed) with his proprietory program, I went to Quackwatch and found out this company, and this owner, is at the center of a very heated and bitter controversy...and folk have apparently died having declined normative or other, treatments, while on his program. I'm disinterested about getting into that controversy, AT ALL, - for me it came down to that when I requested testimonials and examples of his blood work analysis (names removed) so I could see what we would be paying for, I heard no more from them. This company has been around a decade or more, and supposedly do business 'internationally', but the more I probed the slicker it looked, and the less hard data appeared. Folks challenged with serious cancers, ourselves included, can get pretty desperate and the temptation to grasp at hope, especially given the (often) stone wall (regards viable adjunct and integrative and alternative therapies) - that is met by patients dealing with the 'cancer establishment', is very strong and present. It's pretty well Caveat Emptor, I guess. That is, you better know nearly as much as your doctors. If it IS a con, that's monstrous, but as I said, forget it. Those interested and concerned can extrapolate from Ottawa and Cancer online. that's the wonder of LDN to me. Grassroots, real folk, hundreds of testimonials, no promise of "instant cure", just a holding action, maybe, if blessed...and no possible financial gain for any one group or persons. All my instincts tell me it's going to give us the time we need to go to work on bringing Di to better health than she's ever had, and cancer or not. (oh hell, everyone has cancer, all the time - some folk just show it a little more, eh?) I buy the basic principal this guy is pushing, though - that depletion or low levels of one or other essential, or 'provisionally essential' amino could well cascade through the metabolism and bring all sorts of problems. There are a lot of other pathways, however, to helping the body along to restore that balance, without buying a 'pig in a poke sack', nor am I sure that one really has to know the minutae of which and how much - good nutritional strategies such as are discussed here, like the probiotics for example, - may get you to the same place quite quickly, along with reasonable and well defended approaches to 'detoxification', which also makes alot of sense. The chain length thingie remains an open question for me, and I know that Big Pharm DOES make different formulations for blood feeding with this in mind. Explorations will continue and I'll report (link) anything solid and peer-reviewed that I discover as time goes on. We hope Di will not be on TPN so long it will emerge an issue. I know trace vits and mineral deficiencies can emerge on longer courses, for sure. (hey, if man was meant to be fed IV,...:) ) Most sober site I've found discussing cancer therapy is www.lef.org (Life Extension Foundation)- they seem to have found the Golden Mean between allopathic and 'alternative/adjunct' medicine around all this. "Multimodal" being the Key Buzzword.alrightguy123 <alrightguy123@...> wrote: personal opinion: I don't think the length of the chains have muchto do with how well the amino acids are used. Our bodies make quite afew amino acids on their own. There are something like 7 or 10 aminoacids our bodies don't make but need. Maybe a better question is whatis her body making or not making and which amino acids does she need.I don't know if there is a blood test, stool test, urine test thatwould answer these questions. >> I think we're on the same page (though I may be only looking at theillustrations LOL). > The total parenteral nutrition mix that my Diane receives AREnutritional (hopefully), but > the Copaxone protein is 'targeted' at a specific task, as I said,not simply building up metabolic resources. And my issue is, ofcourse, whether better nutritional effect is achieved with shorter, orlonger amino acid chains. > This all is of interest to me because someone (not here) put in myear that the shorter chains aren't as useful, sort of tend to justfloat around in serum and then get wasted. I might have that inverted- simply dunno the science - but the wonderful Dr. Fairful- whois running the TPN Program here has said he'd be open to discussion,amendments. > Since we're making such effort daily with this regime, we want tooptimize the effort, alrightguy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 Supplementary to last post, re: - Life Extention Foundation www.lef.org Figured I'd take a look to see what's up recently, ... Remember that recent big headline article in February JAMA, about how antioxidants will kill you? Check out their rebuttal: - http://www.lef.org/featured-articles/consumer_alert_020307.htm Kewl.alrightguy123 <alrightguy123@...> wrote: personal opinion: I don't think the length of the chains have muchto do with how well the amino acids are used. Our bodies make quite afew amino acids on their own. There are something like 7 or 10 aminoacids our bodies don't make but need. Maybe a better question is whatis her body making or not making and which amino acids does she need.I don't know if there is a blood test, stool test, urine test thatwould answer these questions. >> I think we're on the same page (though I may be only looking at theillustrations LOL). > The total parenteral nutrition mix that my Diane receives AREnutritional (hopefully), but > the Copaxone protein is 'targeted' at a specific task, as I said,not simply building up metabolic resources. And my issue is, ofcourse, whether better nutritional effect is achieved with shorter, orlonger amino acid chains. > This all is of interest to me because someone (not here) put in myear that the shorter chains aren't as useful, sort of tend to justfloat around in serum and then get wasted. I might have that inverted- simply dunno the science - but the wonderful Dr. Fairful- whois running the TPN Program here has said he'd be open to discussion,amendments. > Since we're making such effort daily with this regime, we want tooptimize the effort, alrightguy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 They don't have much on LDN yet, that'll change soon you can bet, but here's something I'll post in full - as it's uplifting for those of us seeking LDN for cancer: - Remember when reading, this fellow had a round of carboplatin and gemcitabine, plus a big gun antiacid (arguably NOT good http://www.newswithviews.com/Howenstine/james21.htm - though obviously indicated sometimes, as here) My Didi had PPI's for the severe reflux that accompanied her Gastroparesis onset, and it remitted - but as we were having very high-level skill AP and EAP for this simultaneously, question remains which did what. you can guess where my vote is cast) Long-Term Survival with Alpha-Lipoic Acid (Intravenous), Multiple Antioxidants, and Low-Dose Naltrexone A recent case report describes the long-term survival (>3 years) of a 46-year-old man who was diagnosed with a very aggressive cancer of the pancreas (adenocarcinoma) which had spread to the liver (Berkson BM et al 2006). The patient had a 3.9 x 3.9 cm tumor in the head of the pancreas and 4 tumors in the liver, one of which was 5 to 6 cm in diameter. He was told there was not much that could be done for him, yet he was treated with one round of a typical chemotherapy regimen (Gemzar® (gemcitabine) and Paraplatin® (carboplatin)), which caused reduced blood cell counts but no tumor regression. He received a second opinion that any further treatment would be in vain, so he opted for an integrative medical approach (via the Integrative Medical Center of New Mexico). For his non-cancer medical conditions he was given several antacids (Prevacid® 30 mg, Rolaids®), antibiotics (Primsol™/Gantanol®), antiulcer agents (Mylanta®, Pepto-Bismol®), and the anti-anxiety drug, Xanax®, and then he started an integrative therapy program, the ALA-LDN (Intravenous Alpha-Lipoic Acid- Low-Dose Naltrexone) protocol. The ALA-LDN protocol comprised alpha-lipoic acid (ALA) (300 to 600 mg intravenously twice weekly), low-dose naltrexone (Vivitrol™)(3 to 4.5 mg at bedtime), and orally, ALA (300 mg twice daily), selenium (200 micrograms twice daily), silymarin (300 mg four times daily), and vitamin B complex (3 high-dose capsules daily). In addition, he maintained a strict dietary regimen, performed a stress-reduction and exercise program, and led a healthy lifestyle. Remarkably, after just one treatment of intravenous ALA his symptoms began to disappear, his quality of life improved, and he had no unwanted side effects. His pancreatic cancer has remained stable for more than 3-years and he is free from symptoms. Several other patients are being treated with this protocol and, to date, with success (Berkson BM et al 2006). Thus, the ALA-LDN protocol could possibly extend the lives of those pancreatic cancer patients who have been led to believe that their cancer is terminal. So How Does It Work? Alpha-lipoic acid is a potent antioxidant (Baraboi VA 2005), improves immune cells’ functions (Mantovani G et al 2000), increases homocysteine levels in cancer cells which is toxic to them (Hultberg B 2003), and prevents the activation of nuclear factor kappaB (NF-kappaB) a key regulator of tumor development and progression (Sokoloski JA et al 1997;Suzuki YJ et al 1992;Vermeulen L et al. 2006). Selenium is useful in elevating antioxidant levels (Woutersen RA et al 1999; Zhan CD et al 2004) and silymarin is a selective COX-2 inhibitor (Cuendet M et al 2000a). Low-dose naltrexone blocks opiate receptors causing the body to make large amounts of opiates in response, which in turn improve the immune response; specifically, natural killer cell cytotoxicity, B-cell and T-cell proliferation, and IFN-gamma production are maintained during times of immune suppression ( CJ et al 2000). Prevacid® is an antacid that also improves cell-mediated immunity, prevents immune suppression, and may also exert anti-inflammatory activity, all of which are important for cancer patients with impaired immune systems (Dattilo M et al 1998; Peddicord TE et al 1999). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 20, 2007 Report Share Posted March 20, 2007 Hi , I'm so sorry Diane has had to endure so much. Please tell her we're thinking of her. From what I've been reading, she has a wonderful, caring husband who is doing everything he can to help her. Now, please correct me if I'm wrong, but my understanding based on what I've read so far is that Diane has been having a great deal of difficulty emptying. If Diane isn't able to manage solid foods, I wonder if a homeopathic liver tonic could help because it's liquid and cleanses the liver. We used to have a fabulous one here in Oz but it went off the market. There are more coming into the healthfood stores now, but the quality is not as good. I admit I have no idea whether it could compromise other digestive issues or whether it would be suitable given her present health challenges, however; it may be worth researching then asking the doc if he/she thinks it could be okay. Just a thought, Cris > > > > I think we're on the same page (though I may be only looking at the > illustrations LOL). > > The total parenteral nutrition mix that my Diane receives ARE > nutritional (hopefully), but > > the Copaxone protein is 'targeted' at a specific task, as I said, > not simply building up metabolic resources. And my issue is, of > course, whether better nutritional effect is achieved with shorter, or > longer amino acid chains. > > This all is of interest to me because someone (not here) put in my > ear that the shorter chains aren't as useful, sort of tend to just > float around in serum and then get wasted. I might have that inverted > - simply dunno the science - but the wonderful Dr. Fairful- who > is running the TPN Program here has said he'd be open to discussion, > amendments. > > Since we're making such effort daily with this regime, we want to > optimize the effort, alrightguy. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2007 Report Share Posted March 27, 2007 This is the way it pans out Scientifically: Amino Acids are the foundation of ALL life and Proteins are the buidling blocks of Amino Acids. That's all I was saying. If you want to get well you have to build up your Proteins. Anne usa. > The page here says: *Copaxone is four Amino Acids consisting of: > > L-Glutamic Acid; L-Alalinine; L-Tyrosine and L-Lysine. > > Tyrosine: Promotes overall health L-Lysine: reduces Herpes- Simplex Viral.Lesions. Ya' know my onw personal theory on MS is: " possibly caused by The Herpes Virus from Mono. > > I cannot comment on on the L-Glutamic or the L-Alanine. I know both are Amino Proteins. > > Proteins are extremely necessary for cell-repair and cell- maintennace. > Combine the Copaxone with the LDN and Vtiamins such as A and B- Compelx w/ Vit.C. IMO. > > > > > > [input] [input] > [input] > Choose a color Black Blue Brown Clear Gold Gray Green Lavender Multi-colored Off-white Orange Peach Pink Purple Red Tan Turquoise White Yellow > Choose a shape 3 sided 5 sided 6 sided 7 sided 8 sided Diamond Oblong Other Rectangle Round Square [input] Close > > Find a Drug [input] [input] Advanced SearchAdvanced Search > > > > > > Advanced Consumer > > Consumer > > > > > Copaxone font size > A > A > A > > > > > Copaxone® (Teva Neuroscience) > (glatiramer acetate injection) > > DESCRIPTION Copaxone® (Teva Neuroscience) > (glatiramer acetate injection) > > COPAXONE® is the brand name for glatiramer acetate (formerly known as copolymer-1). Glatiramer acetate, the active ingredient of COPAXONE®, consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid,L- alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons. > Chemically, glatiramer acetate is designated L-glutamic acid polymer with L-alanine, L-lysine and L-tyrosine, acetate(salt). Its structural formula is: > (Glu, Ala, Lys, Tyr) x.X CH3COOH > (C5H9NO4. C3H7NO2. C6H14N2O2. C9H11NO3) x.x C2H4O2 > CAS- 147245-92-9 > COPAXONE® Injection is a clear, colorless to slightly yellow, sterile, non-pyrogenic solution for subcutaneous injection. Each 1.0 mL of solution contains 20 mg of glatiramer acetate and 40 mg of mannitol, USP. The pH range of the solution is approximately 5.5 to 7.0. The biological activity of COPAXONE® is determined by its ability to block the induction of EAE in mice. > > > > > > > > > > > > > > > --> > > > Check prices for this drug > > > > > > > Get Started > > > > > > News From WebMD > > New FDA Warnings for Anemia Drugs > Tekturna Is First in a New Class of Blood Pressure Drugs > FDA Warns About Asthma Drug, Xolair > FDA Highlights ADHD Drug Warnings > > > > > > > > > > Watch Now. Get Answers. > > > > > > > > > > > WebMD Daily Get breaking medical news. > [input] [input] [input] [input] [input] > > > > > > > > --> > > > Copaxone > > Description > Clinical Pharmacology > Indications & Dosage > Side Effects & Drug Interactions > Warnings & Precautions > Overdosage Contraindictions > Patient Information > > > > > Reference Center > > Health Resources > Prescription Medicine > FDA Overview > Home Pharmacy > Common Health Tests > Family Medical Records > Doctors: Specialties and Training > > > > > Search MedTerms Dictionary for Health Definitions & Medical Abbreviations [input] [input] [input] > > > > > > > Yes! You may freely link to RxListFind out how to add an RxList Search box to your website. > > > > > Get RxList-trusted information when you Google! > > > > > > > > > > > > > > > --> > > > > > > Acid Reflux Disease > Allergic Asthma Info > Alzheimer's Questions? > > Bipolar Rx Info > Bone Health Tips > Cancer Treatments > > Cardiac Device Videos > Dental Health Guide > Heart Failure Solutions > > Hepatitis Treatment > Living with Lymphoma > Skin Care Quiz > > Take Asthma Help Test > Targeting Breast Cancer > Vision Problems? > > > > > > > -->RxList Home| Contact RxList|About RxList|Terms & Conditions|Privacy Policy|Sponsor Policy|More Search Options|Drug Brand Name A-Z > WebMD®|MedScape®|eMedicineHealth®|MedicineNet® Copyright © 2007 by RxList Inc. > RxList does not provide medical advice, diagnosis or treatment. See additional information. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2007 Report Share Posted March 27, 2007 No time to go back to school my friend; the information is here today. See I guess my point with your article and discussion is this: You think the MS is caused by the Immune System attacking the Mylien sheath and the Copaxone acts as a decoy and the I.S. attacks Copaxone? Interesting theory it is possible. My point with the Copaxone is: " Modeled after Aminos which are Nutrtional Proteins needed from food to sustain Life. A.H. > > > > HI Anne, I'm not trying to be " picky " = I think that's a typo - > " Amino Proteins " ...they are amino acids which are the building blocks > of protein?? I dunno really, I'm trying to learn about " short medium > and long chain " amino acids, which as I understand relates to the > degree they've been bonded to lipids, and it affects metabolic > availability - how they then go on to bond to more complex proteins in > the body/cells, etc... > > If so it's interesting that Copaxone is then essentially an amino > acid " balancing " therapy. I like it, whatever the controversy. > > I probably have that " a little knowledge is a dangerous thing " > thing........ > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2007 Report Share Posted March 27, 2007 So you do not thinkg Proteins are Nutrients? or you do not think synthetic proteins are nutrients? ALL Protein is Nutritional. anne.--- In low dose naltrexone , " alrightguy123 " <alrightguy123@...> wrote: > > The Copaxone amino acids are NOT nutritional. It's a protein by > definition because there are multiple amino acids connected together. > > > > > > > If I get the general drift, though, size may be a central issue > regards effective nutritional strategies (i mean in our case, where > we're for now bypassing the gut), whereas if we're trying to target > actual tasks, stimulating certain functions etc, then the > aromatic/alaphatic thingie begins to come into play? And the Copaxone > mix is effectively a small protein. It's al little oblique to our > needs to know this - we're dealing with recnac, not MS - but I guess > I'm naturally curious (though counting my 9 lives ) > > > > S. > > > > > Go back to school and reread the books on amino acids. > > > > Wikipedia has a decent review of amino acids: > > http://en.wikipedia.org/wiki/Amino_acid > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2007 Report Share Posted March 27, 2007 The term " Essential; when referring to Eseential Proteins; Vits. etc. The term Essential means: An essential nutrient which must be obtained from food; and that is all it means. Essential Protein means; cannot be makde from body-obtained from food. > > Yes, there are test for amino acids and really she should be tested and > aminos and other nutrients added to her formula based on those tests. Find a > DAN! doc or orthomolecular doc to do the testing. Metametrix is the name of one > lab that does those tests. > > How much LDN is she on for what period of time. > > mjh > > > Posted by: " alrightguy123 " _alrightguy123@... _ > (mailto:alrightguy123@...?Subject= > Re:%20*Copaxone.....go%20to%20the%20homepage%20of%20Copaxone%20for% 20info..) _alrightguy123 _ (alrightguy123) > Mon Mar 19, 2007 8:46 pm (PST) > personal opinion: I don't think the length of the chains have much > to do with how well the amino acids are used. Our bodies make quite a > few amino acids on their own. There are something like 7 or 10 amino > acids our bodies don't make but need. Maybe a better question is what > is her body making or not making and which amino acids does she need. > I don't know if there is a blood test, stool test, urine test that > would answer these questions. > > > > > > ************************************** AOL now offers free email to everyone. > Find out more about what's free from AOL at http://www.aol.com. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2007 Report Share Posted March 27, 2007 Amino acids are the building blocks of proteins, NOT the other way around. Read up on this material and learn the definitions. If we talk with inaccurate facts to our physicians, they will shut us out and not listen to a word we have to say. I'm checking out. > > This is the way it pans out Scientifically: > > Amino Acids are the foundation of ALL life and Proteins are the > buidling blocks of Amino Acids. > > That's all I was saying. > > If you want to get well you have to build up your Proteins. Anne usa. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2007 Report Share Posted March 28, 2007 hEY ALRIGHT GUY ! (question: do you think the FDA should shut down Cherry Orchards who claim " Cherries cure Gout?) Obviously I meant to write " Amino Acids are the buidling blocks of Protein; but you know what you will realize one day; I hope..is this: One day you will realize this: ALL LIFE; ALL AMINO ACIDS; ALL PROTEINS AND VITAMINS MINERALS HERBS ETC. ARE ALL COMPRISED OUT OF THE SAME BASIC KNOWN NATURAL ELEMENTS. (this is why Natural therapies are often preferred over synthetics.) So you can call me Moe; You can call me Joe; you can call me Shmoe; but please don't call me late to the store to buy my Nutrients; such as " Amino Acids;Proteins;Vitamins;Mineral; Herbs;Protein powders etc. TIP O THE DAY: THE VIT. RIBOFLAVIN B2 IS INDICATED TO TREAT CATARATCHS In low dose naltrexone , " alrightguy123 " <alrightguy123@...> wrote: > > Amino acids are the building blocks of proteins, NOT the other way > around. Read up on this material and learn the definitions. If we > talk with inaccurate facts to our physicians, they will shut us out > and not listen to a word we have to say. > > I'm checking out. > > > > > > > This is the way it pans out Scientifically: > > > > Amino Acids are the foundation of ALL life and Proteins are the > > buidling blocks of Amino Acids. > > > > That's all I was saying. > > > > If you want to get well you have to build up your Proteins. Anne usa. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2007 Report Share Posted March 28, 2007 PS In the world I am thinking of; you won't even have to talk to your Physician;your will get your Alternative Answers from natural sources. > > > > This is the way it pans out Scientifically: > > > > Amino Acids are the foundation of ALL life and Proteins are the > > buidling blocks of Amino Acids. > > > > That's all I was saying. > > > > If you want to get well you have to build up your Proteins. Anne usa. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2007 Report Share Posted March 28, 2007 Please remember that this group is to discuss lowdose Naltrexone. mjhFive other low dose Naltrexone groupsldnsupport, LDN_Users, SpotlightLDN, Autism_LDN, NewGenLDNUsersProceedings of the 2nd LDN Conference, 2006, www.skipspharmacy.comSee what's free at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2007 Report Share Posted March 28, 2007 Please remember that this group is to discuss lowdose Naltrexone. mjhFive other low dose Naltrexone groupsldnsupport, LDN_Users, SpotlightLDN, Autism_LDN, NewGenLDNUsersProceedings of the 2nd LDN Conference, 2006, www.skipspharmacy.comSee what's free at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 28, 2007 Report Share Posted March 28, 2007 Please remember that this group is to discuss lowdose Naltrexone. mjhFive other low dose Naltrexone groupsldnsupport, LDN_Users, SpotlightLDN, Autism_LDN, NewGenLDNUsersProceedings of the 2nd LDN Conference, 2006, www.skipspharmacy.comSee what's free at AOL.com. Quote Link to comment Share on other sites More sharing options...
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