Guest guest Posted March 17, 2007 Report Share Posted March 17, 2007 maybe Diane would be the perfect one to use the LDN PATCH!! someone who knows more about how to procure them, please post this information!! marshirisAOL now offers free email to everyone. Find out more about what's free from AOL at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2007 Report Share Posted March 17, 2007 The sterility requirements for things going into a vein are quite strict. Parenteral things typically come from the factory with the products entire life span from raw materials, manufacturing vessels, personnel wearing " bunny " suits, and final packaging all geared towards parenteral use. > > > I'm newbie here, so hi to all, and good health to all. It's a complex > story, but a simple question: - Can LDN be formulated for IV (or IM - > intramuscular)?.......... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2007 Report Share Posted March 17, 2007 sorry, forgot the term: TRANSDERMAL!! but that's what i meant by saying LDN PATCH!! glad the group cleared that one up!! marshirisAOL now offers free email to everyone. Find out more about what's free from AOL at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2007 Report Share Posted March 17, 2007 For folks that cannot eat the Imu crea transdermal works great cyndi [low dose naltrexone] Re: LDN in IV formulation The sterility requirements for things going into a vein are quitestrict. Parenteral things typically come from the factory with theproducts entire life span from raw materials, manufacturing vessels,personnel wearing "bunny" suits, and final packaging all gearedtowards parenteral use.>> > I'm newbie here, so hi to all, and good health to all. It's a complex> story, but a simple question: - Can LDN be formulated for IV (or IM -> intramuscular)?.......... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2007 Report Share Posted March 17, 2007 Wowzer! What a FANTASTIC support group! Posted my question 6 hours ago, and the ideas/suggestions are flooding in! I never even considered transdermal! Thanks Cyndi! psychrn@... wrote: For folks that cannot eat the Imu crea transdermal works great cyndi [low dose naltrexone] Re: LDN in IV formulation The sterility requirements for things going into a vein are quitestrict. Parenteral things typically come from the factory with theproducts entire life span from raw materials, manufacturing vessels,personnel wearing "bunny" suits, and final packaging all gearedtowards parenteral use.>> > I'm newbie here, so hi to all, and good health to all. It's a complex> story, but a simple question: - Can LDN be formulated for IV (or IM -> intramuscular)?.......... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2007 Report Share Posted March 17, 2007 What does that mean " eat the imu " ? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 18, 2007 Report Share Posted March 18, 2007 This is the pharmacy that supplies the LDN cream for the autistic children. http://www.coastalcompounding.com/ Tyrus compounded it. They will share the compounding info with other compounding pharmacies. I found this info on the web at the following link http://www.autismweb.com/forum/viewtopic.php?p=30910 & sid=37ec940c98673f31176b88e\ c76bd0e55 B Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 18, 2007 Report Share Posted March 18, 2007 Great, thanks for the links. We are working steadily closer to the access and strategy we need. Some interesting questions have been raised though. The cream sound perfect, but: - does it have to be washed off each AM, so as not to continue to trickle in cutaneously throughout the day? Will it make a difference in speed of absorption if it's applied where blood vessels are close to the skin, like the neck/throat? Is this good, bad? Even if there was an IV/IM formulation, would it be TOO quick? You don't want to be having to wake people at 1-2 AM to administer the dose - and giving it at bedtime might have it in and out of the body before the peak of endorphin/metenkaphalin production in the AM hours . Plus the basic question asked by , earlier: - Do we know, with a theoretical IV/IM solution, that the amount reaching or available to opiate receptors would be equivalent to the 3-4.5 mg target range desired? Without an Endocrinologist doing frequent bloodwork, this would be as he said, dangerous. Anyway, ...just some musings. The cream sounds the way forward for us, until Diane's GI tract recovers a modicum of decent transit time, and malabsorption of nutrients and meds has been R/O'd. While Didi is apparently completely refractory to the standard prokinetics, motilin, tegaresod, etc., even IV erythromycin (didn't try po, oral - it was formerly her best tolerated antibiotic) - this may be a factor due lack of bioavailability, not true refractory. She got a lot of these IV in her various Hospital stays, but they were shorter courses than she tried at home, po, and as I understand it can take weeks even with good absorption to begin to resolve things, however much responsive, ultimately. I think though, we are on right track attributing the shut-down to the underlying metastasis: - if the nerve signaling is not getting through for normal Phase I II and III contractions, no amount of prokinetics would help much...right? Can't boost or balance that which isn't there. S. Boyles <boylesn@...> wrote: This is the pharmacy that supplies the LDN cream for the autisticchildren. http://www.coastalcompounding.com/ Tyrus compounded it.They will share the compounding info with other compoundingpharmacies. I found this info on the web at the following linkhttp://www.autismweb.com/forum/viewtopic.php?p=30910 & sid=37ec940c98673f31176b88ec76bd0e55 B Quote Link to comment Share on other sites More sharing options...
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