Guest guest Posted October 4, 2006 Report Share Posted October 4, 2006 Medscape Neurology & Neurosurgery MedPulse® Neurology.Medscape.com SEARCH All Medscape MEDLINE Drug Reference Medscape Features Advertisement - Part 1: Sleep Disturbance and Depression Learn more about the recognizing and treating sleep disturbances and how they relate to managing depression. Advertisement - Treating MS Inflammatory Lesions: Learn more about achieving rapid control of inflammatory lesions in patients who suffer from relapsing forms of multiple sclerosis, click here. Patient Education Find Resources For Your Patients Member Benefits Try a 30-day No Risk trial of ACP Medicine, the reference of the American College of Physicians. Evidence-based, peer-reviewed recommendations on current best practices. Learn More. Contact Us Editorial Comments Marni Kelman, MSc neuroeditor@... Technical Support mpmailings@... Mailing Address WebMD Medscape Attn: Email Newsletters 111 Eighth Avenue, 7th Floor New York, NY 10011 Ensure delivery - add Medscape_Neuro@... to your address book. Advertisement - How Can You Help Change The Cycle Of Migraine? For many patients migraines can be a constant disruption. Learn more about how reducing migraine frequency can help, click here. Top Stories Mayo Researchers Describe New Type of Sleep Apnea Levels of Alzheimer Beta-Amyloid Precursor Protein (APP) in Children With Severely Autistic Behavior and Aggression Malignant Melanoma Increased Before Parkinson's Diagnosis U.S. OKs New Cephalon Cancer Pain Drug Prophylactic Oophorectomy in Young Women s Increased Mortality Risk Browse Neurology and Neurosurgery Content by Topic Feature Articles Psychiatry Diagnosis and Management of ADHD From Adolescence Through Adulthood Symptoms of ADHD evolve during adolescence and into adulthood. What symptoms distinguish ADHD from adolescent rebellion and adult laziness? What treatments are safe and effective in these populations? ADHD, September 2006 Stimulants and cardiovascular status, efficacy and tolerability of long-term atomoxetine, combining atomoxetine and clonidine, and more on the effectiveness of extended-release dexmethylphenidate. Medscape Psychiatry & Mental Health 10(2) 2006 The Neurobiology of ADHD The process of attention is a dance of consciousness requiring the coordination of cortical and subcortical functioning. Explore the complex steps, missteps, and major partners involved. Medscape Psychiatry & Mental Health 11(2) 2006 Stroke Elevated Factor XI Activity Levels Are Associated With an Increased Odds Ratio for Cerebrovascular Events What's the relationship between factor XI activity and cerebrovascular events? Am J Clin Pathol 126(3) 2006 Pediatrics Study of Positron Emission Tomography (PET) Brain Glucose Metabolism to Assess the Efficacy of Tongue and Body Acupuncture in Cerebral Palsy Can tongue and body acupuncture improve the visual status of children with visual disorders, both peripheral and central in origin? J Child Neurol 21(6) 2006 Levels of Alzheimer Beta-Amyloid Precursor Protein (APP) in Children With Severely Autistic Behavior and Aggression Clinical similarities exist between autism and Alzheimer disease. In this study, the authors studied children with and without autism to investigate common pathologic pathways. J Child Neurol 21(6) 2006 Other Neurology Topics FDA Adds New Warnings to Avastin Bevacizumab injection has been linked to rare cases of reversible posterior leukoencephalopathy syndrome and nasal septum perforation. Medscape Medical News 2006 Hypertensive Retinopathy Associated With Use of the Ephedra-Free Weight-Loss Herbal Supplement Hydroxycut The authors present the case of a 42-year-old, previously healthy man who developed malignant hypertension and hypertensive retinopathy while taking Hydroxycut, a caffeine-based ephedra-free supplement. Medscape General Medicine 8(3) 2006 Editorials Nothing to Hide: Transparency in Healthcare R. , MD, FACS, Executive Director of the American College of Surgeons, gives the surgeons' approach to transparency in healthcare. Medscape General Medicine 8(3) 2006 Our Patients Are Sicker -- Posting Grades on the Classroom, Office, or Hospital Door Jerod M. Loeb, PhD, Executive Vice President of the Division of Research at JCAHO, discusses whether grades in healthcare evolve as grades in school. Medscape General Medicine 8(3) 2006 Readers' Responses and Authors' Reply to " Medical Marijuana: Politics Trumps Science at the FDA " Readers respond to " Medical Marijuana: Politics Trumps Science at the FDA, " and the authors of the commentary reply. Medscape General Medicine 8(3) 2006 Does Taking Care Of A Chronically Ill Child Disrupt Sleep? According to a recent study, sleep in caregivers of children with chronic illnesses was significantly disrupted, requiring better interventions and support to improve sleep. Learn more, click here. Industry Spotlight Information from Industry Medical Comorbidities in Mental Illness- View an interactive program presented by Walter Byrd, MD, and Bush, MD, illustrating the importance of monitoring blood glucose in mentally ill patients. News Stroke Depressed Stroke Patients Do Not Receive Adequate Therapy Despite a high rate of depression, which can have a significant impact on stroke survivors' mortality, the majority of clinically depressed stroke patients do not receive antidepressant medication, a new study suggests. Medscape Medical News 2006 Negative Results Left Out of Stroke Literature? Stroke studies that report negative results are less likely to be published than those reporting positive or neutral results, a new study suggests. Medscape Medical News 2006 Alzheimer's Disease Physiologic Function of Alzheimer's Protein Clarified Researchers have determined the normal physiologic function of an enzyme that is critical for the formation of amyloid-beta-peptide in Alzheimer's disease. Reuters Health Information 2006 Headache Estrogen " Withdrawal " Triggers Migraine, Rising Levels Have Protective Effect Falling estrogen levels during the menstrual cycle can trigger migraine attacks, while rising levels of the hormone appear to have a protective effect, a new study suggests. Medscape Medical News 2006 Pain U.S. OKs New Cephalon Cancer Pain Drug The U.S. Food and Drug Administration said on Monday it had approved Cephalon Inc.'s drug Fentora to treat pain in certain cancer patients. Reuters Health Information 2006 EU Regulator to Re-Examine Safety of Old Pain Drugs Europe's drugs regulator said on Tuesday it was launching a fresh review of old pain medicines such as ibuprofen and naproxen in the light of new data suggesting a potential increased risk of heart attack or stroke. Reuters Health Information 2006 Parkinson's Disease Malignant Melanoma Increased Before Parkinson's Diagnosis Results of a study published in the September issue of Epidemiology suggest that the prevalence rates of malignant melanoma and skin carcinoma are increased before a diagnosis of Parkinson's disease. This casts doubt on the notion that levodopa therapy may contribute to the observed higher risk of malignant melanoma in such patients. Reuters Health Information 2006 Epilepsy Sleep-Deprived EEG Increases Diagnostic Yield for New Epilepsy Sleep-deprived EEG offers the best chance of identifying EEG abnormalities in young people with possible new epilepsy, according to a report in the September Journal of Neurology, Neurosurgery, and Psychiatry. Reuters Health Information 2006 Tolerance to Antiepileptic Drugs May Develop Over Time Over time, a significant minority of patients being treated for epilepsy show signs of tolerance to antiepileptic drugs (AEDs), according to a critical review of studies published in the current issue of Epilepsia. Reuters Health Information 2006 Sleep Medicine Sildenafil Worsens Obstructive Sleep Apnea Events In men with severe obstructive sleep apnea, 50 mg of sildenafil worsens bedtime respiratory and desaturation events, according to the results of a double-blind, crossover study reported in the September 18 issue of the Archives of Internal Medicine. Medscape Medical News 2006 Chronic Illness in Children May Cause Chronic Partial Sleep Deprivation in Mothers Mothers of chronically ill children have chronic partial sleep deprivation, especially if their children are dependent on ventilators, according to the results of a study reported in the September 18 issue of the Archives of Internal Medicine. Medscape Medical News 2006 Mayo Researchers Describe New Type of Sleep Apnea In a new paper, researchers report clinical characteristics and prevalence of what they're calling " complex sleep apnea syndrome, " a condition that appears distinct from both obstructive and central sleep apnea. Medscape Medical News 2006 Other Neurology Topics West Nile Virus Will Likely Remain Important Cause of Neurological Disease More than 900 cases of neuroinvasive West Nile virus have been reported so far this year in the United States, on track for a similar incidence to that of recent years. Medscape Medical News 2006 Herpes Zoster Vaccine Effective, but Is It Cost-effective? A new study looks at the cost-effectiveness of a vaccine to prevent shingles and suggests that although it does increase quality-adjusted life-years, it may be within the range considered cost-effective only under certain conditions. Medscape Medical News 2006 U.S. Groups Push for More FDA Funding Biotech companies, medical device makers and food manufacturers joined patient groups and three former U.S. health secretaries on Monday in calling for increased funding for the Food and Drug Administration. Reuters Health Information 2006 Pertussis and Measles Vaccines Not Tied to Encephalopathy Risk Whole-cell pertussis and measles vaccination is not associated with an increased risk for encephalopathy in children, according to a report in the September issue of The Pediatric Infectious Disease Journal. Reuters Health Information 2006 FDA Needs to Fix Post-Market Drug Safety The U.S. Food and Drug Administration needs more staff and funding to fix its monitoring of drug safety after medicines are on the market, the Institute of Medicine (IOM) said on Friday. Reuters Health Information 2006 Prophylactic Oophorectomy in Young Women s Increased Mortality Risk Women younger than 45 years who undergo bilateral oophorectomy and do not receive adequate estrogen therapy were at significantly increased mortality risk, according to researchers. Medscape Medical News 2006 Regulatory Rulings FDA Approvals: Verdeso and Lamictal The FDA has approved desonide 0.05% foam (Verdeso) and a new indication for lamotrigine tablets (Lamictal). Medscape Medical News 2006 FDA Safety Changes: Tysabri and Soma The FDA has approved revisions to the safety labeling for natalizumab intravenous infusion (Tysabri) and carisoprodol tablets (Soma). Medscape Medical News 2006 FDA Approvals: LeadCare II, ClosureFAST, Export XT The FDA has granted a clinical laboratory improvement amendment waiver for a portable lead test (LeadCare II Blood Lead Test System), and approval for a next-generation radiofrequency catheter (ClosureFAST) and a next-generation aspiration catheter (Export XT). Medscape Medical News 2006 U.S. Approves Glaxo's Seizure Drug for Broader Use GlaxoKline Plc said on Monday that U.S. regulators have approved wider use of its seizure drug Lamictal (lamotrigine) to treat grand mal seizures. Reuters Health Information 2006 ADHD, Bone Drugs Studied for FDA by Health Insurers Widely prescribed attention deficit disorder drugs will be the first subject of studies that are being undertaken for U.S. regulators to address the safety of medicines already on the market, according to a lead researcher. Reuters Health Information 2006 International Approvals: , Keppra, ATryn Germany has approved a formoterol plus beclomethasone dipropionate hydrofluoroalkane-propelled inhaler (); the EU has approved a new indication for levetiracetam (Keppra), and a transgenically-produced recombinant form of human antithrombin for infusion (ATryn). Medscape Medical News 2006 First-Time Generic Approvals: Seasonale, Imodium Advanced, and Topamax The FDA has approved first-time generic formulations of levonorgestrel plus ethinyl estradiol (Quasense; Seasonale); nonprescription loperamide HCl plus simethicone (Imodium Advanced Caplets); and topiramate (Topamax). Medscape Medical News 2006 Instant Poll Organ Donation Law Prohibits Relatives' Objections Under the UK Human Tissue Act, as of September 1, relatives are no longer able to block organ donations of loved ones in the United Kingdom. Do you approve or disapprove of this law? To vote or view results of the poll, click on the title above. 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