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Top Stories

CME/CE Highlights of American Academy of Pain Medicine 23rd Annual Meeting

Lisinopril Is Safe and Effective for Hypertension After Acute Ischemic

Stroke

Pathology of Primary Central Nervous System Lymphoma

Changing the Face of Medicine

Neurological Correlates of High-Risk Behavior: A Case Study of Alphonse

Capone

Feature Articles

Conference Coverage

Highlights of American Academy of Pain Medicine 23rd Annual Meeting

Learn about highlights from the American Academy of Pain Medicine 23rd

Annual Meeting.

Stroke

Mental Practice Improves Outcomes in Chronic Stroke

A traditional rehabilitation program that incorporates mental practice of

tasks practiced during therapy significantly improves outcomes in patients

with chronic stroke, according to a study in the April 2007 issue of Stroke.

Reuters Health Information 2007

Systolic Blood Pressure Predicts Stroke Risk for All Population Groups

Systolic blood pressure is an important predictor of stroke risk among men

and women and across racial groups, according to a report in the March issue

of the American Journal of Hypertension.

Reuters Health Information 2007

Lisinopril Is Safe and Effective for Hypertension After Acute Ischemic

Stroke

Lisinopril is a safe and effective hypotensive agent and can be administered

within 24 hours after an acute ischemic stroke, UK researchers report.

Reuters Health Information 2007

EXACT/CAPTURE-2: Postmarketing Carotid Stent Registry Data

Researchers are reporting low rates of death, stroke, and MI and a trend to

better outcomes with increased operator experience in FDA-mandated

postmarketing data for carotid stent and embolic-protection systems.

Medscape Medical News 2007

Sleep Medicine

Minor Brain Injuries Associated With Circadian Rhythm Sleep Disorders

A new study suggests that minor traumatic brain injuries may contribute to

the emergence of new circadian-rhythm sleep disorders, such as delayed

sleep-phase syndrome. Patients complaining of insomnia after a minor brain

injury should be screened for these disorders to avoid misdiagnosis,

researchers say.

Medscape Medical News 2007

Nonapnea Sleep Disturbances Seen to Increase Procoagulant Activity

Concentrations of von Willebrand factor and other procoagulant molecules

increased the more sleep was disrupted in a study of generally healthy

volunteers. Apnea, the investigators contend, may not be the only " toxic "

sleep disturbance.

Heartwire 2007

Headache

Migraine Prophylaxis With Topiramate May Reduce Lost Work Productivity

Preventive treatment with topiramate is associated with a reduction in lost

productivity due to migraines, researchers report.

Reuters Health Information 2007

Parkinson's Disease

Prolonged-Release Ropinirole Effective Adjunctive Therapy in Parkinson's

Disease

Adjunctive therapy with 24-hour prolonged-release ropinirole significantly

reduces " off " time in patients with Parkinson's disease, a new study shows.

Medscape Medical News 2007

Pain

Neuropathic Pain Severity Predicts Response to Duloxetine

Patients with diabetic peripheral neuropathic pain (DPNP) who have more

severe symptoms are more likely to respond to duloxetine, according to a

report in the March issue of Diabetes Care.

Reuters Health Information 2007

Multiple Sclerosis

Fibrin Blockade Promising in Multiple Sclerosis

Blocking the interaction between the microglia integrin receptor Mac-1 and

fibrinogen may disrupt the processes associated with multiple sclerosis

(MS), according to researchers.

Reuters Health Information 2007

Magnetic Stimulation May Improve Multiple Sclerosis Spasticity

Repetitive transcranial magnetic stimulation (rTMS) appears to be a useful

treatment for the spasticity that is often seen with multiple sclerosis,

Italian researchers report.

Reuters Health Information 2007

Neurosurgical Focus

Molecular Pathogenesis of Primary Central Nervous System Lymphoma

The authors of this article discuss the current knowledge of the molecular

pathogenesis of central nervous system lymphomas and review the recent

advances in gene expression profile analysis.

Neurosurg Focus 21(5) 2006

The Role of Cadherins and Catenins in Gliomagenesis

In this review, the authors summarize all studies focusing on the role of

cadherins and catenins in glioma formation in order to devise new

therapeutic approaches.

Neurosurg Focus 21(4) 2006

Distinguishing Primary Central Nervous System Lymphoma From Other Central

Nervous System Diseases: A Neurosurgical Perspective on Diagnostic Dilemmas

and Approaches

This article reviews the cases of 8 patients with either primary central

nervous system lymphoma or multiple sclerosis at the final diagnosis stage.

Neurosurg Focus 21(5) 2006

Subdural Hematomas in Boxing: The Spectrum of Consequences

In this report the authors describe 6 boxers who were evaluated for subdural

hematoma sustained during participation in the sport, and who experienced

remarkably different outcomes.

Neurosurg Focus 21(4) 2006

Pathology of Primary Central Nervous System Lymphoma

This article provides descriptions of the pathologic features of primary

central nervous system lymphoma and discusses the promise shown by several

molecular studies.

Neurosurg Focus 21(5) 2006

Natural Anti-inflammatory Agents for Pain Relief in Athletes

The authors of this article discuss the biochemical pathways of nonsteroidal

drugs, their potentially serious side effects, and the use of natural

supplements.

Neurosurg Focus 21(4) 2006

Concussion in Professional Football: Summary of the Research Conducted by

the National Football League's Committee on Mild Traumatic Brain Injury

In 1994 the National Football League (NFL) initiated a clinical and

biomechanical research study of mild traumatic brain injury (TBI). Read

about the findings and analysis of the Committee.

Neurosurg Focus 21(4) 2006

Sideline and Ringside Evaluation for Brain and Spinal Injuries

This article presents a guide to the sideline or ringside identification and

management of head and spinal injuries.

Neurosurg Focus 21(4) 2006

Participation in Contact or Collision Sports in Athletes With Epilepsy,

Genetic Risk Factors, Structural Brain Lesions, or History of Craniotomy

This article discusses when and if an athlete should be allowed to

participate in contact or collision sports if he or she has structural brain

lesions or a history of craniotomy.

Neurosurg Focus 21(4) 2006

Back and Neck Pain in Triathletes

Learn about this epidemiologic study designed to establish the lifetime

incidence of neck and back pain, gauge the prevalence of discogenic pain,

and identify risk factors among triathletes.

Neurosurg Focus 21(4) 2006

Other Neurology Topics

Neurological Correlates of High-Risk Behavior: A Case Study of Alphonse

Capone

This interesting case study examines the medical history of notorious

criminal Al Capone.

J Neurosci Nurs 38(6) 2006

FDA Announces Recall of 539 & Nephew RF Probes

Use of probes mislabeled as sterile may lead to patient infections.

Medscape Medical News 2007

Pergolide Withdrawn From US Market

With both branded and generic versions being pulled due to potential for

serious heart valve damage, the FDA is urging clinicians to consider

transitioning any Parkinson's disease patients to other dopamine agonists.

Medscape Medical News 2007

Personal Digital Assistants: Practical Advice for Clinicians in 2007

Today's PDA has earned its reputation as a highly useful clinical tool.

Don't miss this comprehensive article if you want to learn more about

choosing and using a PDA.

Topics in Advanced Practice Nursing eJournal 7(1) 2007

Cervical Spine Manipulation: An Alternative Medical Procedure with

Potentially Fatal Complications

A 27-year-old woman had consulted a chiropractor for the first time because

of recurrent episodes of headache and posterior neck pain.

South Med J 100(2) 2007

End-of-Life Care Decisions Must Respect Patient Autonomy, Says AAN

Life-sustaining treatment decisions in patients who have lost their

decision-making capacity must first and foremost respect the autonomy of the

patient and/or the immediate family, according to a position statement

released by the American Academy of Neurology.

Medscape Medical News 2007

Editorials

Changing the Face of Medicine

Darrell G. Kirch, MD, President of the Association of American Medical

Colleges, informs us how to help aspiring docs to actualize.

Medscape General Medicine 9(2) 2007

Improving Laboratory Testing to Save Lives in Resource-Limited Settings,

With a Particular Focus on HIV/AIDS: Humanitarian Efforts by the ASCP

S.J. , MD, FASC, President of the ASCP, describes the laboratory

efforts in African AIDS.

Medscape General Medicine 9(1) 2007

Author's Reply to " Readers Respond to 'Ban Trans Fats in 2007' "

Dansinger, MD, MS, responds to " Readers Respond to 'Ban Trans Fats

in 2007.' "

Medscape General Medicine 9(2) 2007

Readers Respond to " I Use Fingernail Surgery to Remove My Seborrheic

Keratoses "

Readers' responses to Dr. Lundberg's WVE " I Use Fingernail Surgery to

Remove my Seborrheic Keratoses. "

Medscape General Medicine 9(2) 2007

Instant Poll

Preparticipation Screening for CV Abnormalities in Athletes

Last month, the American Heart Association (AHA) reiterated its stance that

preparticipation screening for cardiovascular abnormalities in competitive

athletes is impractical and financially unfeasible. Do you agree or disagree

with the AHA's stance on this issue? To vote or view results of the poll,

click on the title above.

Insomnia: How Can You Improve Diagnosis and Management?

Despite its high prevalence, insomnia is often misunderstood and mismanaged,

which can lead to severe consequences. To learn more about this complex

problem that affects tens of millions of people, visit the Insomnia and

Sleep Health Resource Center.

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