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Top Stories

More Than 5 Million Have Alzheimer's in U.S.

CME/CE Depression in Epilepsy: A New Look at This Disorder

Post-Stroke Antidepressant Treatment May Improve Executive Function

Treatment of Parkinson's Disease

March 2007: In the Wee Small Hours of Cancer

Feature Articles

Epilepsy

Depression in Epilepsy: A New Look at This Disorder

Learn about the significance of depressive disorders and the importance of

their treatment in epilepsy patients.

Psychiatry

A Young Woman With ADHD, Bipolar Disorder, and a Heart Murmur

Psychiatric and medical comorbidities often complicate diagnosis and

management of adult ADHD. What management approach is both safe and

effective?

Medscape Psychiatry & Mental Health 2007

Live: Long-term Tolerability of Antiepileptic Drugs for Neuropsychiatric

Disorders in Women

Women on long-term therapy with antiepileptic drugs for bipolar disorder or

other neuropsychiatric disorders face significant risks and potential

adverse effects.

ALS Caregivers at Greater Risk for Depression, Poor Quality of Life, Than

Patients

Caregivers of individuals with amyotrophic lateral sclerosis are at greater

risk for depression and decreased quality of life than the patients

themselves, a new study has shown.

Medscape Medical News 2007

Efficacy and Tolerability of New and Emerging Agents for Treating ADHD

How can you improve adherence to ADHD treatments? Personalize them. Three

new stimulants and 2 nonstimulants take us a step closer to that ideal.

Medscape Psychiatry & Mental Health 2007

Emerging Trends for Monoamine Oxidase Inhibition in the Management of

Depression: A Patient-Focused, Interactive Program

What recent advances in drug delivery are bringing MAOIs to the forefront in

the treatment of depression?

Parkinson's Disease

Treatment of Parkinson's Disease

The choice between available treatment options depends on clinical

characteristics, but also on the education of the treating physician.

Clin Drug Invest 27(3) 2007

Risedronate Cuts Hip Fracture Risk in Parkinson's Disease

Combination treatment with the bisphosphonate risedronate and vitamin D2

reduces the risk of hip fractures in individuals with Parkinson disease -- a

leading cause of morbidity in this patient group.

Medscape Medical News 2007

Cognitive Decline Mild After Deep Brain Stimulation for Parkinson's Disease

Patients experience mild cognitive declines that have little impact on daily

living activities in the 5 years after subthalamic nucleus stimulation for

Parkinson's disease.

Reuters Health Information 2007

Smoking Temporally Associated With Reduced Parkinson's Disease Risk

A new study adds to evidence that cigarette smoking protects against

Parkinson's disease. Specifically, the research shows a temporal

relationship between smoking and reduced risk of PD. That is, the protective

effect wanes after smokers quit.

Reuters Health Information 2007

Phase 3 NIH Study to Test Creatine in Early Parkinson's Disease

The National Institute of Neurological Disorders and Stroke announced today

it is launching a large-scale clinical trial to determine whether the

nutritional supplement creatine can slow the progression of Parkinson's

disease.

Medscape Medical News 2007

Stroke

Post-Stroke Antidepressant Treatment May Improve Executive Function

Impaired executive function is common and often permanent following stroke.

However, new study findings suggest that treatment with antidepressants may

help patients recover their cognitive and psychosocial capacities.

Reuters Health Information 2007

Urgent Intervention to Reduce Functional Deficits After Postoperative Stroke

The authors describe a patient with acute cardioembolic stroke with minimal

infarction in Broca's area and a surrounding region of potentially

salvageable, hypoperfused cortex.

Nat Clin Pract Neurol 3(3) 2007

Composition, Not Size, of Carotid Plaques May Determine Stroke Risk

A new study suggests a higher proportion of calcification in carotid plaque

may indicate a lower risk of developing stroke symptoms, regardless of

absolute plaque volume, a finding that may signal a paradigm shift in stroke

risk assessment. (Stroke 2007)

Medscape Medical News 2007

Sleep Medicine

Sleep Apnea Linked to Silent Brain Infarction, Increased Platelet Activation

In men with moderate to severe obstructive sleep apnea, the prevalence of

silent brain infarctions is significantly higher than in obese subjects

without sleep apnea or individuals with mild sleep apnea, Japanese

investigators report. Biomarkers of inflammation and platelet activation

also tend to be present in higher concentrations in patients with moderate

to severe obstructive sleep apnea.

Reuters Health Information 2007

Alzheimer's Disease

More Than 5 Million Have Alzheimer's in U.S.

More than 5 million people in the United States have Alzheimer's disease,

and an aging population is likely to fuel a steady rise in new cases,

according to a report released by the Alzheimer's Association on Tuesday.

Reuters Health Information 2007

Some Drugs May Speed Deterioration in Alzheimer's Disease

There is considerable variation in the rate of decline associated with

various drugs prescribed for patients with Alzheimer's disease. Drugs

licensed to treat dementia tend to correlate with a slower decline, while

antipsychotics and benzodiazepines tend to speed the rate of deterioration.

Reuters Health Information 2007

Other Neurology Topics

Mechanisms of Disease: DNA Repair Defects and Neurological Disease

Learn about the current state of knowledge regarding neurological diseases

that have an etiological link with DNA repair defects in this article.

Nat Clin Pract Neurol 3(3) 2007

Effect of Intraarterial Papaverine and/or Angioplasty on the Cerebral Veins

in Patients With Vasospasm After Subarachnoid Hemorrhage Due to Ruptured

Intracranial Aneurysms

Is there a change in intracranial venous diameters after endovascular

treatment of carotid distribution vasospasm caused by subarachnoid

hemorrhage?

Neurosurg Focus 21(3) 2006

Inside the " Small World " of Pediatric Oncology

A pediatric fellow in neuro-oncology offers up thoughtful observations on

medical ethics, pop culture, and yes -- kids with brain tumors.

Medscape Med Students 2007

An Ethical Dilemma Involving a Shy-Drager Patient: A Case Study

The nurse, as patient advocate, must help bridge the gap between the

patient's wishes and the physician's decision.

J Neurosci Nurs 38(6) 2006

Narrow Eligibility Criteria Threaten Applicability of Clinical Trial Results

Randomized controlled trials are essential for effective medical policy

decisions and for maintaining up-to-date medical practice, but the

applicability of the results is threatened when eligibility criteria are too

strict, exclusive, or inadequately defined, researchers report in the

Journal of the American Medical Association for March 21.

Reuters Health Information 2007

Editorials

March 2007: In the Wee Small Hours of Cancer

After surgery for head and neck melanoma in early January of this year, I

was told that my condition was much more severe than originally envisioned.

The note below was written to some family members.

Medscape Radiology 2007

About Intercessory Prayer: The Scientific Study of Miracles

Intercessory prayer implies miracles. Miracles imply the Power of God. The

author argues that theology is not within the science or medicine domain and

suggests a startling but unambiguous experiment.

Medscape General Medicine 9(1) 2007

Carotid Screening Guidelines -- Overvalued

J. Veith, MD, Professor of Surgery at NYU Medical Center and the

Cleveland Clinic Foundation, discusses whether carotid artery screening can

prevent a stroke.

Medscape General Medicine 9(1) 2007

Instant Poll

NSAIDs in Patients at High Risk for Heart Disease

The American Heart Association recently issued new guidance discouraging the

use of both cyclooxygenase 2 (COX-2) inhibitors and other nonsteroidal

anti-inflammatory drugs (NSAIDs) in patients with heart disease or those at

high risk of developing heart disease. For patients at high risk and in

pain, how would you advise? To vote or view results of the poll, click on

the title above.

The Scope of Breakthrough Pain in Clinical Practice

Read about the diagnosis, definitions, and challenges of breakthrough pain,

as well as the latest nonpharmacologic and nonopioid treatments options.

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