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Aciphex and Pancrease contradictions?

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Wow, isn't there some differences in opinion on this topic. Duh ! You would

think we all would just know about these things.

To all, keep us all posted on this issue

Best Wishes, Poncho - GA

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Dear ,

My first reaction was to say that I didn't think it would hurt to take

the Aciphex with Pancrease, which is the generic name of

Pancrelipase, since the enzymes are just amylase, protease

and lipase components as would be produced by your pancreas

(if it were working correctly). BUT, I decided to research this

further before making a statement I wasn't perfectly sure about,

so I did some searching with my favorite pharmaceutical

website:

http://www.rxlist.com/

This was the statement found under the Pancrease listing:

DRUG INTERACTIONS

Antacids containing calcium carbonate and magnesium

hydroxide should not be taken concurrently with pancrelipase.

The combination of calcium carbonate and magnesium

hydroxide with pancrelipase may precipitate glycine-conjugated

bile acids and may form calcium and magnesium fatty acid

soaps, causing a decrease in fat absorption and thus an

increase in steatorrhea.

Found on the Aciphex listing were it's ingredients. Magnesium

stearate and magnesium oxide were two of the listed

ingredients, but not magnesium hydroxide. Not being a chemist,

I don't know exactly what these components are or how they

differ.

You may wish to research this further to find a clear answer. I

know several of us do take antiacids in addition to our pancreatic

enzymes. Though many of us take different antiacids, like

Prilosec or Prevacid or others, and different pancreatic enzymes,

such as Viokase, Ultrase or Creon. I am curious now myself

about this in relation to what I'm taking and plan to investigate it

further.

With hope and prayers,

Heidi

Heidi H. Griffeth

South Carolina

SE & SW Regional Rep

PAI, Intl.

Note: Comments or advice are personal opinion only, and

should not be substituted for professional medical consultation.

> i was wondering about my medicines. i take aciphex for acid

reflux and am supposed to take pancrease with my meals. do

they work against each other?

> jessica

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