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Re: Biracial son

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Hi Danelle,

you're not alone, even not on this list, but you are right that is is

difficult to find info about black CF patients. I have copied below

one article that says, that in 1997 there were 600 black CF patients

in the CF Foundation National Patient Registry. I don't know how they

classify biracial patients.

Maybe you should contact your local CFF chapter or the CFF itself to

ask for additional info. May I ask what mutations Chas has?

Peace

Torsten, dad of Fiona 5wcf

J Pediatr 1998 Feb;132(2):255-9 Related Articles, Links

Comment in:

J Pediatr. 1998 Feb;132(2):202-3.

J Pediatr. 1999 Jan;134(1):122-3.

Comparison of the clinical manifestations of cystic fibrosis in black

and white patients.

Hamosh A, Fitz- SC, Macek M Jr, Knowles MR, Rosenstein BJ,

Cutting GR.

Department of Pediatrics and Center for Medical Genetics, s

Hopkins University School of Medicine, Baltimore, land 21287-

3914, USA.

No large-scale studies of the incidence or disease severity of cystic

fibrosis (CF) in black patients have been reported to date. In this

study, the CF Foundation National Patient Registry was used to

establish new incidence figures and to compare the clinical status of

U.S. black (n = 601) and white patients (n = 17,755) with CE Results

indicate that the incidence of CF is approximately 1 in 3,200 white

and 1 in 15,000 black live births in the United States. Black

patients with CF are currently, and were at diagnosis, younger and

have poorer nutritional status and pulmonary function than white

patients with CF. Fewer have meconium ileus, but more have distal

intestinal obstruction syndrome. To control for genotype, each black

deltaF508 homozygote (n = 47) was compared with four age- and sex-

matched white deltaF508 homozygotes. Only the difference in

nutritional status remained. The deltaF508 mutation is associated

with higher levels of meconium ileus than other genotypes,

independent of race. In conclusion, the clinical manifestations of CF

are similar in black and white patients except for poorer nutritional

status in black patients, which appears to be independent of age and

genotype.

PMID: 9506637 [PubMed - indexed for MEDLINE]

> Hi! I was wondering if anyone out there knows someone with CF who

is of another race than Caucasian. My son is mixed with black and

white and as far as I know he is the only in our are that is mixed

with another race. I have found very little research on children of

black descent that have CF. I knew nothing of the disease before his

diagnosis except that it was genetic and there is no cure. I am still

very scared about what it will mean for him as a growing child. I

guess I just try to keep educating myself.

>

> Thanks, le mom of Chas (18 moss) wcf

>

>

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In a message dated 2/3/2003 11:41:23 PM Central Standard Time,

sauerd74@... writes:

> Hi! I was wondering if anyone out there knows someone with CF who is of

> another race than Caucasian. My son is mixed with black and white and as

> far as I know he is the only in our are that is mixed with another race. I

> have found very little research on children of black descent that have CF.

> I knew nothing of the disease before his diagnosis except that it was

> genetic and there is no cure. I am still very scared about what it will

> mean for him as a growing child. I guess I just try to keep educating

> myself.

>

> Thanks, le mom of Chas (18 moss) wcf

You need to talk to ! WHERE ARE YOU??? Deb A

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Hi le,

When I was living in Oklahoma, I met a young mom and her two beautiful

daughters; the youngest had CF. This was probably around

1997--can't really remember, and the little girl was about a year

old at the time. The girls' dad is black and at that time, they

couldn't identify which CF gene he had. The mom carried the DeltaF508

gene.

I'm embarrassed to say that I can't remember the mom's name. We met a

couple times and our children used the same CF specialist (we didn't

use the CF Center at Children's Hospital).

If you want to make contact with other African American/Caucasion's

affected by CF, then email me privately and I'll send you the doctor's

name. If they're still patients of his, then perhaps he or his nurse

will pass along your name and contact info to that mom.

Kim

Mom of (23 1/2 with cf and asthma) and (20 with asthma

and CF)

Hi! I was wondering if anyone out there knows someone with CF who is

of another race than Caucasian. My son is mixed with black and white

and as far as I know he is the only in our are that is mixed with

another race. I have found very little research on children of black

descent that have CF. I knew nothing of the disease before his

diagnosis except that it was genetic and there is no cure. I am still

very scared about what it will mean for him as a growing child. I

guess I just try to keep educating myself.

Thanks, le mom of Chas (18 moss) wcf

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le,

T. from this group is black and of course has Milan. I have a

friend in Hawaii who is Caucasian (from England actually) and her

husband is black. They have two daughters, one with CF and one

without.

CHristy

> Hi! I was wondering if anyone out there knows someone with CF who

is of another race than Caucasian. My son is mixed with black and

white and as far as I know he is the only in our are that is mixed

with another race. I have found very little research on children of

black descent that have CF. I knew nothing of the disease before his

diagnosis except that it was genetic and there is no cure. I am still

very scared about what it will mean for him as a growing child. I

guess I just try to keep educating myself.

>

> Thanks, le mom of Chas (18 moss) wcf

>

>

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le,

Here in Colorado I have friends whose daughter has cf. Her mom is

white and dad is black. They have 4 kids and it worked out exactly

like to textbook genetics square: 1 with cf, 2 carriers, one no

carrier.

-Lenora

>le,

> T. from this group is black and of course has Milan. I have a

>friend in Hawaii who is Caucasian (from England actually) and her

>husband is black. They have two daughters, one with CF and one

>without.

>CHristy

>

>

>

>

>> Hi! I was wondering if anyone out there knows someone with CF who

>is of another race than Caucasian. My son is mixed with black and

>white and as far as I know he is the only in our are that is mixed

>with another race. I have found very little research on children of

>black descent that have CF. I knew nothing of the disease before his

>diagnosis except that it was genetic and there is no cure. I am still

>very scared about what it will mean for him as a growing child. I

>guess I just try to keep educating myself.

>>

>> Thanks, le mom of Chas (18 moss) wcf

>>

>>

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