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If your child is not talking or talking poorly, odds are his hearing is

affected.

Hearing is extremely 'tricky'. Fluid can come and go from the ears profoundly

affecting language development and motor development. He may be hearing you

some of the time but not all of the time. He may only partially be hearing some

sounds. It is a complex system. The ears are tied to balance and motor

function through the vestibular system (semi-circular canals) and the vestibular

system is also tied to the eyes. Thus any disfunction or recurring infection in

the ears drastically affects development. Even a loss of a few months can

impair a childs overall neurological development leaving you to play 'catch-up'

with him for years.

Before you do anything else, you must have your child's ears thoroughly

investigated by an ENT and explore the possibility of tubes. Look for the

possibility of milk intolerances as this is extremely common with chronic ear

issues. Whatever you do, you must ensure that he is 'physically' hearing as

soon as possible. After you know that his hearing is up to par, then you need

to stimulate his ears with sound; play music in the house, read him stories and

engage him with eye-to-eye contact and conversation as much as possible. Turn

off the TV and have him 'listening'. Stimulate, stimulate, stimulate.

Janice

[sPAM] [ ] Hi..... I need help

My sone is 14 mo and he isnt talking. the doctor says it can be because

His hearing is bad but he can hear anything we say or do. could it be

anything else? he was advanced with everything but walking and talking.

what can i do to help him along?

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" If your child is not talking or talking poorly, odds are his hearing

is affected " .

This is not necessarily true for apraxic children!

Hearing certainly needs to be addressed in speech delay, and a lower

threshhold for tubes in an apraxic child with chronic ear infections

or fluid should be considered. And true that the first part of the

eval for delayed speech should be a visit to the audiologist -

because some kids have hearing loss for a variety of reasons that

could impact speech. And regardless of hearing, sign language should

be initiated early in speech delay. (Signingtime videos are awesome).

However ear infections are one of the most common infections of

childhood, and millions of children have chronic ear infections

without speech and motor delays. It may be part of the apraxia

puzzle, because it seems chronic ear infections, sinus infections etc

are common in this group of kids, but only a piece that contributes

to these apraxic children's problems. More likely there is something

different about their immune system that leads to increased

susceptibility to infections. And undiagnosed allergies cause

inflammation of the sinuses...leading to fluid in the ears, and

rhinitis/sinusitis. So looking for allergies is a good idea in this

group since so many of the children have often undiagnosed allergies

and chronic gut issues.

But, the speech delay for childhood apraxia of speech is

neurological in origin...independent of hearing. Most apraxic kids

hear just fine. They know what they want to say...but can't do the

motor planning it takes to speak. And all the talking and stimulating

in the world is not going to get them to imitate you. THEY CAN'T

imitate, no matter how much they WANT to...which makes it so

frustrating and is classic for this disorder. It takes lots of drill

and repetition for them to train their mouths/tongue to move in a way

that will produce speech. You often have to literally move their

tongue into position...showing them physically how to motor plan, and

giving them visual cues. This is why PROMPT therapy is so helpful.

See interesting abstract below that I came across at the Toronto

pediatric meeting. Here's a neurodevelopmental pediatrician also

finding a high frequency of gluten-sensitivity in his autistic

population that does not seem to be " classic celiac disease " . He has

also identified abnormailties in the CD8 counts (the supressor cells

that keep you immune system in check, and with low CD8...the body may

over-react to things that it shouldn't (ie food and environmental

allergies), bringing us back to the leaky inflammed gut issue. All

pretty interesting. -claudia

[5880.8] Immune Dysregulation in a Cohort of Children with Autism

Spectrum

Disorders

Faber, Carolyn Kobelak, Caminos.. Medicine, The

Children's

Institute, Pittsburgh, PA.

BACKGROUND: Children with autism spectrum disorders demonstrate

increased

frequency of immunologic abnormalities including signs of elevated

innate

and humoral immunity. T and B cell subsets provide a method of

assessing T

helper (CD4) and suppressor (CD8) cell ratio, which influences B cell

antibody production. Elevated CD4/CD8 ratio can lead to excessive B

cell

antibody production, increasing the creation of cross-reactive

antibodies

that can mediate autoimmune and inflammatory reactions. About 10% of

children are sensitive to gluten, as demonstrated by increased

antigliadin

IgG and/or IgA antibody production. Only 1% of children demonstrate

elevated

tissue transglutaminase (tTGA), suggesting the presence of celiac

disease.

OBJECTIVE: This study sought to determine the frequency and pattern of

immunological abnormalities in a cohort of children with autism

spectrum

disorders, to search for a set of immunologic markers that help

define this

population.

DESIGN/METHODS: A retrospective review of data from 47 children (35

male, 12

female, mean age 5.71, SD 3.4 ) with Autistic Disorder, PDD.NOS, and

Asperger's Disorder diagnosed by structured interview, rating scales,

and

play observation was performed. T and B cell subset, serum

immunoglobulin,

antigliadin antibody, and tTGA data, obtained after the diagnostic

visit,

was reviewed.

RESULTS: CD4 number was elevated in 22 children (47 %), while CD4% was

elevated in 14 children (30 %). CD8 number was decreased in 19

children (40

%) while CD8% was low in 42 children (89 %). Elevated CD4/CD8 ratio

was

found in 24 children (51 %). Total B cell (CD19) number was elevated

in 24

(51 %) of the children while total T cell (CD3) number was increased

in 20

(43 %) of the children. Abnormalities of NK cell % or number were

present in

38 (81 %) of the children. Three, one, and 10 children displayed

elevations

of serum IgG, IgA, and IgM respectively. Twenty-five children (53 %)

demonstrated antigliadin IgG elevations, while three (6 %) had

increased

antigliadin IgA. Elevated tTGA was not seen in the cohort.

CONCLUSIONS: Children with autism spectrum disorders frequently

display high

CD4/CD8 ratios, supporting the presence of hyperreactivity of the

humoral

immune system. Low CD8% may be a sensitive marker of immune

dysregulation in

this population. Innate immune system (NK cell) dysfunction and gluten

sensitivity, without evidence of celiac disease, are commonly present.

> If your child is not talking or talking poorly, odds are his

hearing is affected.

>

> Hearing is extremely 'tricky'. Fluid can come and go from the ears

profoundly affecting language development and motor development. He

may be hearing you some of the time but not all of the time. He may

only partially be hearing some sounds. It is a complex system. The

ears are tied to balance and motor function through the vestibular

system (semi-circular canals) and the vestibular system is also tied

to the eyes. Thus any disfunction or recurring infection in the ears

drastically affects development. Even a loss of a few months can

impair a childs overall neurological development leaving you to

play 'catch-up' with him for years.

>

> Before you do anything else, you must have your child's ears

thoroughly investigated by an ENT and explore the possibility of

tubes. Look for the possibility of milk intolerances as this is

extremely common with chronic ear issues. Whatever you do, you must

ensure that he is 'physically' hearing as soon as possible. After

you know that his hearing is up to par, then you need to stimulate

his ears with sound; play music in the house, read him stories and

engage him with eye-to-eye contact and conversation as much as

possible. Turn off the TV and have him 'listening'. Stimulate,

stimulate, stimulate.

>

> Janice

>

>

> [sPAM] [ ] Hi..... I need help

>

>

> My sone is 14 mo and he isnt talking. the doctor says it can be

because

> His hearing is bad but he can hear anything we say or do. could

it be

> anything else? he was advanced with everything but walking and

talking.

> what can i do to help him along?

>

>

>

>

>

>

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Guest guest

This one is long and involved, but I wish you would read it thoroughly

when you are in the mood to!

Love, Mama

claudia.morris wrote:

>

>

> " If your child is not talking or talking poorly, odds are his hearing

> is affected " .

>

> This is not necessarily true for apraxic children!

>

> Hearing certainly needs to be addressed in speech delay, and a lower

> threshhold for tubes in an apraxic child with chronic ear infections

> or fluid should be considered. And true that the first part of the

> eval for delayed speech should be a visit to the audiologist -

> because some kids have hearing loss for a variety of reasons that

> could impact speech. And regardless of hearing, sign language should

> be initiated early in speech delay. (Signingtime videos are awesome).

> However ear infections are one of the most common infections of

> childhood, and millions of children have chronic ear infections

> without speech and motor delays. It may be part of the apraxia

> puzzle, because it seems chronic ear infections, sinus infections etc

> are common in this group of kids, but only a piece that contributes

> to these apraxic children's problems. More likely there is something

> different about their immune system that leads to increased

> susceptibility to infections. And undiagnosed allergies cause

> inflammation of the sinuses...leading to fluid in the ears, and

> rhinitis/sinusitis. So looking for allergies is a good idea in this

> group since so many of the children have often undiagnosed allergies

> and chronic gut issues.

>

> But, the speech delay for childhood apraxia of speech is

> neurological in origin...independent of hearing. Most apraxic kids

> hear just fine. They know what they want to say...but can't do the

> motor planning it takes to speak. And all the talking and stimulating

> in the world is not going to get them to imitate you. THEY CAN'T

> imitate, no matter how much they WANT to...which makes it so

> frustrating and is classic for this disorder. It takes lots of drill

> and repetition for them to train their mouths/tongue to move in a way

> that will produce speech. You often have to literally move their

> tongue into position...showing them physically how to motor plan, and

> giving them visual cues. This is why PROMPT therapy is so helpful.

>

> See interesting abstract below that I came across at the Toronto

> pediatric meeting. Here's a neurodevelopmental pediatrician also

> finding a high frequency of gluten-sensitivity in his autistic

> population that does not seem to be " classic celiac disease " . He has

> also identified abnormailties in the CD8 counts (the supressor cells

> that keep you immune system in check, and with low CD8...the body may

> over-react to things that it shouldn't (ie food and environmental

> allergies), bringing us back to the leaky inflammed gut issue. All

> pretty interesting. -claudia

>

>

> [5880.8] Immune Dysregulation in a Cohort of Children with Autism

> Spectrum

> Disorders

>

>

> Faber, Carolyn Kobelak, Caminos.. Medicine, The

> Children's

> Institute, Pittsburgh, PA.

>

>

> BACKGROUND: Children with autism spectrum disorders demonstrate

> increased

> frequency of immunologic abnormalities including signs of elevated

> innate

> and humoral immunity. T and B cell subsets provide a method of

> assessing T

> helper (CD4) and suppressor (CD8) cell ratio, which influences B cell

> antibody production. Elevated CD4/CD8 ratio can lead to excessive B

> cell

> antibody production, increasing the creation of cross-reactive

> antibodies

> that can mediate autoimmune and inflammatory reactions. About 10% of

> children are sensitive to gluten, as demonstrated by increased

> antigliadin

> IgG and/or IgA antibody production. Only 1% of children demonstrate

> elevated

> tissue transglutaminase (tTGA), suggesting the presence of celiac

> disease.

> OBJECTIVE: This study sought to determine the frequency and pattern of

> immunological abnormalities in a cohort of children with autism

> spectrum

> disorders, to search for a set of immunologic markers that help

> define this

> population.

> DESIGN/METHODS: A retrospective review of data from 47 children (35

> male, 12

> female, mean age 5.71, SD 3.4 ) with Autistic Disorder, PDD.NOS, and

> Asperger's Disorder diagnosed by structured interview, rating scales,

> and

> play observation was performed. T and B cell subset, serum

> immunoglobulin,

> antigliadin antibody, and tTGA data, obtained after the diagnostic

> visit,

> was reviewed.

> RESULTS: CD4 number was elevated in 22 children (47 %), while CD4% was

> elevated in 14 children (30 %). CD8 number was decreased in 19

> children (40

> %) while CD8% was low in 42 children (89 %). Elevated CD4/CD8 ratio

> was

> found in 24 children (51 %). Total B cell (CD19) number was elevated

> in 24

> (51 %) of the children while total T cell (CD3) number was increased

> in 20

> (43 %) of the children. Abnormalities of NK cell % or number were

> present in

> 38 (81 %) of the children. Three, one, and 10 children displayed

> elevations

> of serum IgG, IgA, and IgM respectively. Twenty-five children (53 %)

> demonstrated antigliadin IgG elevations, while three (6 %) had

> increased

> antigliadin IgA. Elevated tTGA was not seen in the cohort.

> CONCLUSIONS: Children with autism spectrum disorders frequently

> display high

> CD4/CD8 ratios, supporting the presence of hyperreactivity of the

> humoral

> immune system. Low CD8% may be a sensitive marker of immune

> dysregulation in

> this population. Innate immune system (NK cell) dysfunction and gluten

> sensitivity, without evidence of celiac disease, are commonly present.

>

>

>

>

>

>> If your child is not talking or talking poorly, odds are his

>>

> hearing is affected.

>

>> Hearing is extremely 'tricky'. Fluid can come and go from the ears

>>

> profoundly affecting language development and motor development. He

> may be hearing you some of the time but not all of the time. He may

> only partially be hearing some sounds. It is a complex system. The

> ears are tied to balance and motor function through the vestibular

> system (semi-circular canals) and the vestibular system is also tied

> to the eyes. Thus any disfunction or recurring infection in the ears

> drastically affects development. Even a loss of a few months can

> impair a childs overall neurological development leaving you to

> play 'catch-up' with him for years.

>

>> Before you do anything else, you must have your child's ears

>>

> thoroughly investigated by an ENT and explore the possibility of

> tubes. Look for the possibility of milk intolerances as this is

> extremely common with chronic ear issues. Whatever you do, you must

> ensure that he is 'physically' hearing as soon as possible. After

> you know that his hearing is up to par, then you need to stimulate

> his ears with sound; play music in the house, read him stories and

> engage him with eye-to-eye contact and conversation as much as

> possible. Turn off the TV and have him 'listening'. Stimulate,

> stimulate, stimulate.

>

>> Janice

>>

>>

>> [sPAM] [ ] Hi..... I need help

>>

>>

>> My sone is 14 mo and he isnt talking. the doctor says it can be

>>

> because

>

>> His hearing is bad but he can hear anything we say or do. could

>>

> it be

>

>> anything else? he was advanced with everything but walking and

>>

> talking.

>

>> what can i do to help him along?

>>

>>

>>

>>

>>

>>

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